What are the cheapest airlines to fly from Ohio to St. Louis one-way?

$48 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Delta and Frontier, with prices starting from $61 and $86, respectively.

What are the most popular routes from Ohio to St. Louis?

While some choose either Cleveland Hopkins Intl - Lambert-St Louis or Pittsburgh - Lambert-St Louis, Detroit Metropolitan Wayne County - Lambert-St Louis is the most popular route from Ohio to St. Louis.

What are the most popular airlines that fly from Ohio to St. Louis?

When booking a flight from Ohio to St. Louis, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

How far in advance should I book a flight from Ohio to St. Louis?

Travelers have found it’s best to book a flight 59 days in advance to save up to 144% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 59 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Ohio to St. Louis 1-2 weeks in advance for as low as $333, or $416 for flights within the next 24 hours.

What is the cheapest month to fly from Ohio to St. Louis?

June is one of the best times of the year to fly to St. Louis from Ohio. Prices for June average $316 per person but you can even find prices for as low as $142. The most expensive prices can be found in the month of January. Opting for a June flight can save you 53% on your journey compared to booking in January

What airport do you fly into for flights to St. Louis from Ohio?

Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Ohio to St. Louis.

Can I find deals for flights from Ohio to St. Louis that include hotel bookings?

Yes. In addition to deals on Ohio to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Ohio to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to St. Louis.

Can I find deals for business class flights from Ohio to St. Louis?

Yes. Cheapflights offers flight deals from Ohio to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$48+ Flights from Ohio to St. Louis - Compare & Save Big

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Cheap flight deals from Ohio to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$178 (Frontier)
One-way from	$48 (FlightHub)
Popular in	January
Cheapest in	June
Average price	$295
Good round-trip deal	$284 or less
Good one-way deal	$146 or less

Provider with most accurate pricing for Cleveland Hopkins Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Lambert-St Louis flights.

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From Ohio to Lambert-St Louis

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One-way flight from Ohio to Lambert-St Louis

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Highest demand for flights based on searches. 14% potential increase in price ($53 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($16 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Price to beat on a round-trip flight from Ohio to Lambert-St Louis.

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Price to beat on a one-way flight from Ohio to Lambert-St Louis.

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Find flight deals from Ohio to St. Louis

Cheapest flights from Ohio to St. Louis
Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Sun 5/189:10 amCLE - STL

1 stop15h 56mFrontier

Wed 5/218:15 pmSTL - CLE

1 stop13h 48mFrontier

Deal found 4/30

$180

Wed 5/2112:57 pmCVG - STL

1 stop11h 47mFrontier

Sat 5/245:35 pmSTL - CVG

1 stop16h 24mFrontier

Deal found 4/30

$181

Wed 5/285:16 pmDTW - STL

1 stop5h 10mAmerican Airlines

Wed 6/45:12 amSTL - DTW

1 stop5h 05mAmerican Airlines

Deal found 4/30

$199

Tue 6/36:15 pmCMH - STL

1 stop6h 36mAmerican Airlines

Thu 6/55:30 amSTL - CMH

1 stop6h 12mAmerican Airlines

Deal found 4/29

$199

Wed 5/288:00 amCLE - STL

Nonstop1h 40mSouthwest

Wed 5/286:40 pmSTL - CLE

Nonstop1h 30mSouthwest

Deal found 4/30

$201

Sun 5/1812:54 pmDTW - STL

1 stop12h 12mFrontier

Sun 5/255:45 pmSTL - DTW

1 stop14h 02mFrontier

Deal found 4/30

$210

Wed 5/286:05 amCLE - STL

1 stop4h 51mUnited Airlines

Wed 5/285:27 pmSTL - CLE

1 stop3h 33mUnited Airlines

Deal found 4/30

$211

Sat 7/511:16 amDAY - STL

1 stop4h 21mDelta

Sat 8/96:00 amSTL - DAY

1 stop4h 20mDelta

Deal found 4/30

$214

Tue 7/226:05 amDTW - STL

2 stops7h 30mSouthwest

Sun 7/277:15 amSTL - DTW

1 stop8h 55mSouthwest

Deal found 4/29

$215

Fri 5/96:14 pmPIT - STL

1 stop7h 00mFrontier

Sun 5/115:45 pmSTL - PIT

1 stop22h 39mFrontier

Deal found 4/30

$216

Wed 5/284:10 pmDTW - STL

Nonstop1h 37mDelta

Wed 6/410:45 amSTL - DTW

Nonstop1h 30mDelta

Deal found 4/30

$217

Tue 5/272:25 pmCMH - STL

1 stop7h 14mDelta

Tue 6/35:40 pmSTL - CMH

1 stop5h 28mDelta

Deal found 4/29

$221

Best flights from Ohio to St. Louis
Discover carefully curated flight deals from Ohio to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Fri 5/97:29 pmCVG - STL

1 stop5h 45mFrontier

Mon 5/125:45 pmSTL - CVG

1 stop6h 14mFrontier

Deal found 4/29

$178

Wed 5/285:16 pmDTW - STL

1 stop5h 10mAmerican Airlines

Wed 6/45:12 amSTL - DTW

1 stop5h 05mAmerican Airlines

Deal found 4/30

$199

Wed 5/288:00 amCLE - STL

Nonstop1h 40mSouthwest

Wed 5/286:40 pmSTL - CLE

Nonstop1h 30mSouthwest

Deal found 4/30

$201

Wed 5/286:05 amCLE - STL

1 stop4h 51mUnited Airlines

Wed 5/285:27 pmSTL - CLE

1 stop3h 33mUnited Airlines

Deal found 4/30

$211

Sat 7/511:16 amDAY - STL

1 stop4h 21mDelta

Sat 8/96:00 amSTL - DAY

1 stop4h 20mDelta

Deal found 4/30

$214

Thu 6/127:25 amDTW - STL

3 stops28h 08mSpirit Airlines

Sun 6/156:12 pmSTL - DTW

Nonstop1h 28mSpirit Airlines

Deal found 4/30

$225

Sun 5/1810:31 amDTW - STL

2 stops9h 10mMultiple Airlines

Sun 5/2510:20 amSTL - DTW

1 stop24h 02mMultiple Airlines

Deal found 4/30

$277

Sun 5/189:10 amCLE - STL

1 stop15h 56mFrontier

Wed 5/218:15 pmSTL - CLE

1 stop13h 48mFrontier

Deal found 4/30

$180

Tue 6/36:15 pmCMH - STL

1 stop6h 36mAmerican Airlines

Thu 6/55:30 amSTL - CMH

1 stop6h 12mAmerican Airlines

Deal found 4/29

$199

Tue 7/226:05 amDTW - STL

2 stops7h 30mSouthwest

Sun 7/277:15 amSTL - DTW

1 stop8h 55mSouthwest

Deal found 4/29

$215

Wed 5/284:10 pmDTW - STL

Nonstop1h 37mDelta

Wed 6/410:45 amSTL - DTW

Nonstop1h 30mDelta

Deal found 4/30

$217

Sun 5/1812:54 pmDTW - STL

1 stop12h 12mFrontier

Sun 5/255:45 pmSTL - DTW

1 stop14h 02mFrontier

Deal found 4/30

$210

Last-minute flights from Ohio to St. Louis
Discover last-minute flight deals from Ohio to St. Louis. Data last updated May 1, 2025 and is based on user searches.

Mon 5/53:05 pmCLE - STL

1 stop10h 01mFrontier

Thu 5/85:45 pmSTL - CLE

1 stop13h 28mFrontier

Deal found 4/29

$184

Mon 5/57:18 pmCLE - STL

1 stop22h 57mSpirit Airlines

Thu 5/810:10 amSTL - CLE

2 stops29h 26mSpirit Airlines

Deal found 4/29

$447

Wed 5/73:59 pmCVG - STL

1 stop5h 40mDelta

Sat 5/1012:59 pmSTL - CVG

1 stop5h 27mDelta

Deal found 4/30

$415

Wed 5/79:38 pmDTW - STL

2 stops22h 03mMultiple Airlines

Fri 5/99:50 amSTL - DTW

3 stops22h 20mMultiple Airlines

Deal found 4/30

$432

Thu 5/85:59 pmCMH - STL

1 stop7h 07mFrontier

Sat 5/105:45 pmSTL - CMH

1 stop22h 24mFrontier

Deal found 4/30

$230

Thu 5/86:00 amDAY - STL

1 stop4h 00mDelta

Fri 5/165:40 pmSTL - DAY

1 stop4h 53mDelta

Deal found 4/30

$254

Thu 5/86:05 amCLE - STL

1 stop5h 42mDelta

Tue 5/132:15 pmSTL - CLE

1 stop3h 35mDelta

Deal found 4/30

$429

Thu 5/86:50 pmCLE - STL

1 stop4h 10mSouthwest

Tue 5/136:25 amSTL - CLE

2 stops7h 20mSouthwest

Deal found 4/30

$434

Fri 5/96:14 pmPIT - STL

1 stop7h 00mFrontier

Sun 5/115:45 pmSTL - PIT

1 stop22h 39mFrontier

Deal found 4/30

$216

Fri 5/95:28 pmDAY - STL

1 stop5h 24mAmerican Airlines

Wed 5/147:00 amSTL - DAY

1 stop5h 37mAmerican Airlines

Deal found 4/30

$314

Fri 5/96:01 pmPIT - STL

2 stops16h 14mSpirit Airlines

Sun 5/1110:10 amSTL - PIT

2 stops35h 10mSpirit Airlines

Deal found 4/30

$389

Sat 5/1012:57 pmCVG - STL

1 stop12h 09mFrontier

Sun 5/115:45 pmSTL - CVG

1 stop6h 14mFrontier

Deal found 4/30

$200

One-way flights from Ohio to St. Louis
Search for one-way flight options from Ohio to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Thu 6/124:33 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Deal found 4/30

$48

Thu 7/38:55 amDTW - STL

Nonstop1h 42mDelta

Deal found 4/30

$61

Wed 5/2112:57 pmCVG - STL

1 stop11h 47mFrontier

Deal found 4/30

$86

Mon 5/56:09 pmCLE - STL

1 stop6h 57mFrontier

Deal found 4/30

$89

Mon 5/56:14 pmPIT - STL

1 stop6h 52mFrontier

Deal found 4/30

$89

Sat 5/105:59 pmCMH - STL

1 stop7h 07mFrontier

Deal found 4/30

$89

Wed 6/47:08 amCMH - STL

1 stop3h 41mAmerican Airlines

Deal found 4/29

$95

Tue 6/178:05 amCLE - STL

Nonstop1h 35mSouthwest

Deal found 4/29

$101

Wed 6/41:48 pmCVG - STL

1 stop20h 27mMultiple Airlines

Deal found 4/30

$104

Wed 5/281:52 pmDTW - STL

1 stop10h 52mFrontier

Deal found 4/30

$105

Wed 7/26:00 pmCLE - STL

1 stop5h 45mUnited Airlines

Deal found 4/30

$106

Tue 6/108:35 pmCMH - STL

Nonstop1h 25mSouthwest

Deal found 4/29

$106

Cheapflights Fare Finder

Use the filters below to find and compare flights from Ohio to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Sun 5/18

9:10 am-12:06 am

1 stop15h 56m

Lambert-St Louis

Wed 5/21

8:15 pm-11:03 am

1 stop13h 48m

$180

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Wed 5/21

12:57 pm-11:44 pm

1 stop11h 47m

Lambert-St Louis

Sat 5/24

5:35 pm-10:59 am

1 stop16h 24m

$181

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 5/28

5:16 pm-9:26 pm

1 stop5h 10m

Lambert-St Louis

Wed 6/4

5:12 am-11:17 am

1 stop5h 05m

$199

ColumbusSt. Louis

CMH - STL

CMHSTL

Columbus

Tue 6/3

6:15 pm-11:51 pm

1 stop6h 36m

Lambert-St Louis

Thu 6/5

5:30 am-12:42 pm

1 stop6h 12m

$199

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Wed 5/28

8:00 am-8:40 am

Nonstop1h 40m

Lambert-St Louis

Wed 5/28

6:40 pm-9:10 pm

Nonstop1h 30m

$201

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sun 5/18

12:54 pm-12:06 am

1 stop12h 12m

Lambert-St Louis

Sun 5/25

5:45 pm-8:47 am

1 stop14h 02m

$210

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

Wed 5/28

6:05 am-9:56 am

1 stop4h 51m

Lambert-St Louis

Wed 5/28

5:27 pm-10:00 pm

1 stop3h 33m

$211

DaytonSt. Louis

DAY - STL

DAYSTL

Dayton

Sat 7/5

11:16 am-2:37 pm

1 stop4h 21m

Lambert-St Louis

Sat 8/9

6:00 am-11:20 am

1 stop4h 20m

$214

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Tue 7/22

6:05 am-12:35 pm

2 stops7h 30m

Lambert-St Louis

Sun 7/27

7:15 am-5:10 pm

1 stop8h 55m

$215

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Fri 5/9

6:14 pm-12:14 am

1 stop7h 00m

Lambert-St Louis

Sun 5/11

5:45 pm-5:24 pm

1 stop22h 39m

$216

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 results

...

Best time to book a flight from Ohio to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Ohio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to St. Louis

What is the cheapest month to book a flight from Ohio to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Ohio to St. Louis (average of $311). Flying from Ohio to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to STL?

When flying from Ohio to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Ohio to St. Louis, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Alaska Airlines

8.0

Very good

9,968 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Southwest

8.0

Very good

4,294 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Delta

8.0

Very good

7,934 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

United Airlines

7.4

Good

8,696 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

What airport do you fly into for flights to St. Louis from Ohio?
Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Ohio to St. Louis.
What are the cheapest airlines to fly from Ohio to St. Louis one-way?
$48 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Delta and Frontier, with prices starting from $61 and $86, respectively.
What are the most popular routes from Ohio to St. Louis?
While some choose either Cleveland Hopkins Intl - Lambert-St Louis or Pittsburgh - Lambert-St Louis, Detroit Metropolitan Wayne County - Lambert-St Louis is the most popular route from Ohio to St. Louis.
Can I find deals for flights from Ohio to St. Louis that include hotel bookings?
Yes. In addition to deals on Ohio to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Ohio to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to St. Louis.
Can I find deals for business class flights from Ohio to St. Louis?
Yes. Cheapflights offers flight deals from Ohio to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Ohio to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Ohio to St. Louis (average of $311). Flying from Ohio to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Fenton

Maryland Heights

Fairview Heights

Collinsville

Wentzville

Eureka

St. Peters

Festus

Glencoe

Alton

Farmington

O'Fallon

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Ohio to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$116	Average$170	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$162	Average$335	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$181	Average$338	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$193	Average$364	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$227	Average$332	FlexibilityNo cancel fee	On-time63%

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$48+ Cheap flights from Ohio to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Ohio to St. Louis with Cheapflights

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3. Compare prices and book

Cheap flight deals from Ohio to St. Louis

Keep the following information in mind while searching for Ohio to St. Louis flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Ohio to St. Louis

Cheapest flights from Ohio to St. LouisExplore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Ohio to St. Louis that are best for you.

Best time to book a flight from Ohio to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Ohio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Ohio to St. Louis

What is the cheapest month to book a flight from Ohio to St. Louis?

What is the cheapest time of day to fly from OH to STL?

Find hourly flight availability from Ohio to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Ohio to St. Louis, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Ohio to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Ohio?

What are the cheapest airlines to fly from Ohio to St. Louis one-way?

What are the most popular routes from Ohio to St. Louis?

Can I find deals for flights from Ohio to St. Louis that include hotel bookings?

How can I find direct flights from Ohio to St. Louis?

Can I find deals for business class flights from Ohio to St. Louis?

What is the cheapest month to book a flight from Ohio to St. Louis?

Traveling to a place near Ohio?

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Alternative routes for Ohio to St. Louis

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Top 5 airlines flying from Ohio to St. Louis

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Cheapest flights from Ohio to St. Louis
Explore the most affordable flight options available from Ohio to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.