$333+ Cheap flights from Jacksonville, NC to St. Louis (OAJ - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
OAJ — STL
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to St. LouisExplore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Jacksonville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:52 pm -
1 stop4h 51m
Mon 9/281:54 pm -
1 stop3h 56m
Deal found 9/6![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:34 pm -
1 stop6h 08m
Mon 9/286:00 am -
1 stop4h 15m
Deal found 9/9![Delta logo]()
$537
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:34 pm -
1 stop6h 08m
Sun 9/202:30 pm -
1 stop6h 52m
Deal found 9/5![Delta logo]()
$586
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:52 pm -
2 stops7h 52m
Sun 9/2012:50 pm -
1 stop6h 05m
Deal found 9/5![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:15 am -
2 stops8h 48m
Sun 9/275:00 am -
2 stops8h 24m
Deal found 9/6![American Airlines logo]()
$767
Best flights from Jacksonville to St. LouisDiscover carefully curated flight deals from Jacksonville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Jacksonville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:52 pm -
1 stop4h 51m
Mon 9/281:54 pm -
1 stop3h 56m
Deal found 9/6![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:34 pm -
1 stop6h 08m
Mon 9/286:00 am -
1 stop4h 15m
Deal found 9/9![Delta logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:52 pm -
2 stops11h 35m
Sun 9/275:15 am -
1 stop6h 01m
Deal found 9/6![American Airlines logo]()
$662
Last-minute flights from Jacksonville to St. LouisDiscover last-minute flight deals from Jacksonville to St. Louis. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to St. Louis. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:34 pm -
1 stop6h 08m
Sun 9/202:30 pm -
1 stop6h 52m
Deal found 9/5![Delta logo]()
$586
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:52 pm -
2 stops7h 52m
Sun 9/2012:50 pm -
1 stop6h 05m
Deal found 9/5![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:52 pm -
1 stop4h 51m
Mon 9/281:54 pm -
1 stop3h 56m
Deal found 9/6![American Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:34 pm -
1 stop6h 08m
Mon 9/286:00 am -
1 stop4h 15m
Deal found 9/9![Delta logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:15 am -
2 stops8h 48m
Sun 9/275:00 am -
2 stops8h 24m
Deal found 9/6![American Airlines logo]()
$767
One-way flights from Jacksonville to St. LouisSearch for one-way flight options from Jacksonville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Jacksonville to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:02 pm -
1 stop6h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:34 pm -
1 stop6h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:52 pm -
2 stops8h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$634
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
3 stops59h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$1,008
Find flight deals from Jacksonville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (OAJ) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $507 (American Airlines) |
One-way from | $333 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Jacksonville to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Fri 12/11
6:02 pm-11:58 pm
1 stop6h 56m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$333
Quickest round-trip
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Mon 9/14
6:34 pm-11:42 pm
1 stop6h 08m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$445
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Thu 9/24
1:52 pm-5:43 pm
1 stop4h 51m
Lambert-St Louis
Mon 9/28
1:54 pm-6:50 pm
1 stop3h 56m
$507
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Thu 9/24
6:34 pm-11:42 pm
1 stop6h 08m
Lambert-St Louis
Mon 9/28
6:00 am-11:15 am
1 stop4h 15m
$537
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Mon 9/14
1:52 pm-9:43 pm
2 stops8h 51m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$634
JacksonvilleSt. Louis
OAJ Jacksonville Albert J Ellis - STL Lambert-St Louis
OAJSTL
Jacksonville Albert J Ellis
Thu 9/24
1:52 pm-12:27 am
2 stops11h 35m
Lambert-St Louis
Sun 9/27
5:15 am-12:16 pm
1 stop6h 01m
$662
Sorted by cheapest first
Compare providers for flights from Jacksonville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Jacksonville, North Carolina-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville, North Carolina-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville, North Carolina-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville, North Carolina-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville, North Carolina-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Jacksonville with our price prediction graph.
OAJ-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 10, 2026.
Read reviews from past customers who have flown Delta from Jacksonville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Edwardsville
Glencoe
Chesterfield
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Jacksonville and St. Louis flights
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Top airline flying from Jacksonville to St. Louis
Discover the top airline that operate flights from Jacksonville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$314 | Average$460 | FlexibilityNo cancel fee | On-timeN/A |