$140+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Aug 22 — Aug 291
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in December or January, booked 62 days in advance, depart on a Saturday or Wednesday and return on a Saturday
Cheap flight deals from Milwaukee to Spartanburg
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Best
Last-minute
One-way
Cheapest flights from Milwaukee to SpartanburgExplore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Sat 8/159:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Mon 8/179:43 pm
CLT
- MKE
1 stop14h 30m
Frontier
Deal found 7/19![Frontier logo]()
$268
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Sat 9/198:11 pm
CLT
- MKE
1 stop24h 04m
Frontier
Deal found 7/22![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:10 pm
MKE
- CLT
1 stop15h 28m
Frontier
Mon 10/191:33 pm
CLT
- MKE
1 stop6h 42m
Frontier
Deal found 7/22![Frontier logo]()
$272
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Mon 8/109:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Sun 10/410:02 pm
CLT
- MKE
1 stop22h 13m
Frontier
Deal found 7/19![Frontier logo]()
$278
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:10 pm
MKE
- CLT
1 stop15h 28m
Frontier
Mon 10/121:33 pm
CLT
- MKE
1 stop6h 42m
Frontier
Deal found 7/22![Frontier logo]()
$280
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:10 pm
MKE
- CLT
1 stop23h 55m
Frontier
Sun 9/278:11 pm
CLT
- MKE
1 stop24h 04m
Frontier
Deal found 7/22![Frontier logo]()
$285
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:10 pm
MKE
- CLT
1 stop24h 40m
Frontier
Mon 9/79:52 pm
CLT
- MKE
1 stop14h 21m
Frontier
Deal found 7/19![Frontier logo]()
$286
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/59:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$288
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:01 am
MKE
- CLT
1 stop8h 15m
American Airlines
Wed 12/24:54 pm
CLT
- MKE
Nonstop2h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$289
Best flights from Milwaukee to SpartanburgDiscover carefully curated flight deals from Milwaukee to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Milwaukee to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:10 pm
MKE
- CLT
1 stop15h 28m
Frontier
Mon 10/121:33 pm
CLT
- MKE
1 stop6h 42m
Frontier
Deal found 7/18![Frontier logo]()
$340
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:30 pm
MKE
- CLT
1 stop3h 40m
Southwest
Sat 9/263:25 pm
CLT
- MKE
1 stop4h 35m
Southwest
Deal found 7/19![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:20 pm
MKE
- CLT
1 stop4h 30m
Southwest
Wed 9/911:10 am
CLT
- MKE
2 stops9h 45m
Southwest
Deal found 7/21![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:40 am
MKE
- CLT
1 stop4h 05m
Southwest
Fri 8/147:40 am
CLT
- MKE
1 stop5h 15m
Southwest
Deal found 7/21![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:55 am
MKE
- CLT
1 stop3h 40m
Southwest
Tue 10/66:40 am
CLT
- MKE
1 stop4h 10m
Southwest
Deal found 7/18![Southwest logo]()
$396
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:45 am
MKE
- CLT
2 stops7h 50m
Southwest
Sat 8/297:55 am
CLT
- MKE
2 stops8h 50m
Southwest
Deal found 7/20![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:20 am
MKE
- CLT
2 stops10h 10m
Southwest
Mon 10/129:00 pm
CLT
- MKE
1 stop4h 15m
Southwest
Deal found 7/18![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:45 am
MKE
- CLT
1 stop5h 00m
Southwest
Fri 8/286:30 pm
CLT
- MKE
1 stop3h 55m
Southwest
Deal found 7/20![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:45 am
MKE
- CLT
2 stops9h 40m
Southwest
Sun 8/3012:25 pm
CLT
- MKE
2 stops8h 50m
Southwest
Deal found 7/21![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:55 am
MKE
- CLT
2 stops5h 40m
Southwest
Thu 10/81:35 pm
CLT
- MKE
2 stops11h 40m
Southwest
Deal found 7/23![Southwest logo]()
$457
Last-minute flights from Milwaukee to SpartanburgDiscover last-minute flight deals from Milwaukee to Spartanburg. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to Spartanburg. Data last updated July 23, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Mon 8/109:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$273
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/59:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$288
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 8/109:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$304
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:43 am
MKE
- CLT
1 stop12h 21m
Frontier
Sat 8/89:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$319
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:43 am
MKE
- CLT
1 stop12h 21m
Frontier
Mon 8/109:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$300
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Wed 8/59:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$315
This Frontier deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/129:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/21![Frontier logo]()
$320
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Sat 8/159:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/19![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Mon 8/179:43 pm
CLT
- MKE
1 stop14h 30m
Frontier
Deal found 7/19![Frontier logo]()
$268
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
MKE
- CLT
1 stop9h 52m
American Airlines
Thu 8/138:47 pm
CLT
- MKE
Nonstop2h 00m
American Airlines
Deal found 7/22![American Airlines logo]()
$297
This CheapOair deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:43 am
MKE
- CLT
1 stop27h 10m
Frontier
Wed 8/269:52 pm
CLT
- MKE
1 stop14h 21m
Frontier
Deal found 7/23![Frontier logo]()
$314
This CheapOair deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:10 pm
MKE
- CLT
1 stop24h 40m
Frontier
Sat 8/299:52 pm
CLT
- MKE
1 stop14h 21m
Frontier
Deal found 7/20![Frontier logo]()
$278
One-way flights from Milwaukee to SpartanburgSearch for one-way flight options from Milwaukee to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Milwaukee to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:10 pm
MKE
- CLT
1 stop18h 51m
Frontier
Deal found 7/18![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Deal found 7/22![Frontier logo]()
$142
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Deal found 7/19![Frontier logo]()
$149
This CheapOair deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:10 pm
MKE
- CLT
1 stop24h 40m
Frontier
Deal found 7/21![Frontier logo]()
$150
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:30 pm
MKE
- CLT
1 stop3h 40m
Southwest
Deal found 7/23![Southwest logo]()
$161
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Deal found 7/18![Frontier logo]()
$170
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:00 am
MKE
- CLT
2 stops5h 55m
Southwest
Deal found 7/22![Southwest logo]()
$171
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:45 am
MKE
- CLT
2 stops10h 50m
Southwest
Deal found 7/21![Southwest logo]()
$172
This Frontier deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Deal found 7/20![Frontier logo]()
$175
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:43 am
MKE
- CLT
1 stop27h 10m
Frontier
Deal found 7/20![Frontier logo]()
$177
Find flight deals from Milwaukee to Spartanburg
Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (Frontier) |
One-way from | $140 (CheapOair) |
Popular in | March |
Cheapest in | December |
Average price | $470 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 10/9
8:10 pm-12:38 pm
1 stop15h 28m
Charlotte Douglas
Mon 10/12
1:33 pm-7:15 pm
1 stop6h 42m
$340
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sat 9/19
1:30 pm-6:10 pm
1 stop3h 40m
Charlotte Douglas
Sat 9/26
3:25 pm-7:00 pm
1 stop4h 35m
$355
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 9/4
4:20 pm-9:50 pm
1 stop4h 30m
Charlotte Douglas
Wed 9/9
11:10 am-7:55 pm
2 stops9h 45m
$384
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Tue 8/11
7:40 am-12:45 pm
1 stop4h 05m
Charlotte Douglas
Fri 8/14
7:40 am-11:55 am
1 stop5h 15m
$390
Quickest round-trip
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 10/2
5:55 am-10:35 am
1 stop3h 40m
Charlotte Douglas
Tue 10/6
6:40 am-9:50 am
1 stop4h 10m
$396
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sun 8/23
5:45 am-2:35 pm
2 stops7h 50m
Charlotte Douglas
Sat 8/29
7:55 am-3:45 pm
2 stops8h 50m
$406
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 10/9
10:20 am-9:30 pm
2 stops10h 10m
Charlotte Douglas
Mon 10/12
9:00 pm-12:15 am
1 stop4h 15m
$412
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sun 8/23
5:45 am-11:45 am
1 stop5h 00m
Charlotte Douglas
Fri 8/28
6:30 pm-9:25 pm
1 stop3h 55m
$437
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 8/28
5:45 am-4:25 pm
2 stops9h 40m
Charlotte Douglas
Sun 8/30
12:25 pm-8:15 pm
2 stops8h 50m
$447
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sun 10/4
5:55 am-12:35 pm
2 stops5h 40m
Charlotte Douglas
Thu 10/8
1:35 pm-12:15 am
2 stops11h 40m
$457
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
MKE-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to Spartanburg
MKE-SB1
MKE-CLT
What is the cheapest time of day to fly from MKE to SB1?
Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 23, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Milwaukee to Spartanburg as you normally would.
Weekly flight availability from Milwaukee to Spartanburg
Explore weekly flight availability from Milwaukee to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 23, 2026.
The most flights from MKE to SB1 are scheduled on a Monday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Milwaukee to Spartanburg?
Airfare is below average for this route at the moment.
Milwaukee to Spartanburg flights typically cost between $416 and $517 in August.The cheapest round-trip price found within the last 5 days was $258 on Frontier (Aug 11-Aug 15).
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated July 23, 2026.
See what other customers who have flown with Southwest and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to Spartanburg
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Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Milwaukee to Spartanburg by cabin class
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Milwaukee and Spartanburg flights
Browse other Milwaukee and Spartanburg flight options. Last updated on July 23, 2026.
Other flights from Milwaukee
Browse through other flights departing from Milwaukee. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
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Milwaukee to Spartanburg flights
Consider these flights traveling from Milwaukee to Spartanburg.
Top 4 airlines flying from Milwaukee to Spartanburg
Discover the top 4 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$227 | Average$354 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$301 | Average$432 | FlexibilityNo cancel fee | On-time63% |