$129+ Cheap flights from Milwaukee (MKE) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CLT
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Milwaukee-Mitchell to Spartanburg are usually found in July or June, booked 34 days in advance, depart on a Wednesday or Saturday and return on a Wednesday
Cheap flight deals from Milwaukee to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Milwaukee to SpartanburgExplore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Milwaukee to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Sat 7/258:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/4![Frontier logo]()
$258
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:43 am
MKE
- CLT
1 stop12h 21m
Frontier
Sat 7/188:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$263
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 7/208:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/6![Frontier logo]()
$268
This Booking.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Sat 7/412:29 pm
CLT
- MKE
1 stop20h 29m
Frontier
Deal found 6/5![Frontier logo]()
$270
This Orbitz deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Sat 7/118:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/7![Frontier logo]()
$284
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Mon 7/68:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$289
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 7/1310:59 pm
CLT
- MKE
1 stop9h 59m
Frontier
Deal found 6/5![Frontier logo]()
$294
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:20 am
MKE
- CLT
1 stop6h 30m
Southwest
Tue 8/258:05 am
CLT
- MKE
1 stop4h 00m
Southwest
Deal found 6/7![Southwest logo]()
$299
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am
MKE
- CLT
2 stops7h 50m
Southwest
Thu 10/156:45 am
CLT
- MKE
1 stop4h 00m
Southwest
Deal found 6/7![Southwest logo]()
$305
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Wed 7/88:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/8![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Wed 7/228:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$313
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Wed 7/88:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$315
Best flights from Milwaukee to SpartanburgDiscover carefully curated flight deals from Milwaukee to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Milwaukee to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am
MKE
- CLT
2 stops7h 50m
Southwest
Thu 10/156:45 am
CLT
- MKE
1 stop4h 00m
Southwest
Deal found 6/7![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:40 am
MKE
- CLT
1 stop4h 46m
Delta
Sat 7/251:17 pm
CLT
- MKE
1 stop3h 45m
Delta
Deal found 6/5![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:40 am
MKE
- CLT
2 stops10h 20m
Southwest
Sat 8/221:00 pm
CLT
- MKE
1 stop6h 25m
Southwest
Deal found 6/3![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:14 pm
MKE
- CLT
1 stop6h 44m
Delta
Tue 7/149:42 am
CLT
- MKE
1 stop4h 00m
Delta
Deal found 6/4![Delta logo]()
$412
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:00 pm
MKE
- CLT
1 stop4h 05m
Southwest
Mon 10/262:35 pm
CLT
- MKE
1 stop5h 25m
Southwest
Deal found 6/6![Southwest logo]()
$402
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:47 pm
MKE
- CLT
1 stop4h 10m
Delta
Mon 7/136:00 am
CLT
- MKE
1 stop3h 39m
Delta
Deal found 6/5![Delta logo]()
$422
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am
MKE
- CLT
2 stops10h 25m
Southwest
Tue 10/66:35 pm
CLT
- MKE
1 stop4h 35m
Southwest
Deal found 6/3![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:34 am
MKE
- CLT
1 stop4h 29m
Delta
Sun 8/237:54 pm
CLT
- MKE
1 stop4h 59m
Delta
Deal found 6/4![Delta logo]()
$427
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:15 pm
MKE
- CLT
1 stop3h 35m
Southwest
Wed 7/17:05 pm
CLT
- MKE
1 stop3h 55m
Southwest
Deal found 6/3![Southwest logo]()
$415
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:45 pm
MKE
- CLT
1 stop4h 33m
Delta
Sun 11/89:35 am
CLT
- MKE
1 stop3h 52m
Delta
Deal found 6/6![Delta logo]()
$437
Last-minute flights from Milwaukee to SpartanburgDiscover last-minute flight deals from Milwaukee to Spartanburg. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to Spartanburg. Data last updated June 8, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Sat 7/412:29 pm
CLT
- MKE
1 stop20h 29m
Frontier
Deal found 6/5![Frontier logo]()
$270
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Mon 7/68:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$289
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Wed 7/88:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$315
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Mon 7/68:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/8![Frontier logo]()
$320
This Orbitz deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Sat 7/118:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/7![Frontier logo]()
$284
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Wed 7/88:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/8![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 7/1310:59 pm
CLT
- MKE
1 stop9h 59m
Frontier
Deal found 6/5![Frontier logo]()
$294
This Frontier deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:43 am
MKE
- CLT
1 stop12h 21m
Frontier
Wed 7/158:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/8![Frontier logo]()
$334
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:43 am
MKE
- CLT
1 stop12h 21m
Frontier
Sat 7/188:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$263
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 7/208:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/6![Frontier logo]()
$268
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Wed 7/228:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/5![Frontier logo]()
$313
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:43 am
MKE
- CLT
1 stop25h 46m
Frontier
Sat 7/258:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 6/4![Frontier logo]()
$258
One-way flights from Milwaukee to SpartanburgSearch for one-way flight options from Milwaukee to Spartanburg. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Milwaukee to Spartanburg. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Deal found 6/7![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Deal found 6/7![Frontier logo]()
$134
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:43 am
MKE
- CLT
1 stop7h 00m
Frontier
Deal found 6/7![Frontier logo]()
$138
This Booking.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:43 am
MKE
- CLT
1 stop26h 34m
Frontier
Deal found 6/7![Frontier logo]()
$140
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:20 am
MKE
- CLT
1 stop4h 40m
Southwest
Deal found 6/8![Southwest logo]()
$155
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Deal found 6/7![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:43 am
MKE
- CLT
1 stop7h 00m
Frontier
Deal found 6/5![Frontier logo]()
$179
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:40 pm
MKE
- CLT
1 stop4h 30m
Southwest
Deal found 6/5![Southwest logo]()
$184
Find flight deals from Milwaukee to Spartanburg
Keep the following information in mind while searching for Milwaukee to Spartanburg flight deals. Data was last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (Expedia) |
One-way from | $129 (Frontier) |
Popular in | March |
Cheapest in | July |
Average price | $393 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Milwaukee to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Wed 10/7
5:45 am-2:35 pm
2 stops7h 50m
Charlotte Douglas
Thu 10/15
6:45 am-9:45 am
1 stop4h 00m
$305
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Wed 8/19
7:40 am-7:00 pm
2 stops10h 20m
Charlotte Douglas
Sat 8/22
1:00 pm-6:25 pm
1 stop6h 25m
$389
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Sat 10/17
2:00 pm-7:05 pm
1 stop4h 05m
Charlotte Douglas
Mon 10/26
2:35 pm-7:00 pm
1 stop5h 25m
$402
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Wed 7/22
5:40 am-11:26 am
1 stop4h 46m
Charlotte Douglas
Sat 7/25
1:17 pm-4:02 pm
1 stop3h 45m
$407
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 10/2
7:50 am-7:15 pm
2 stops10h 25m
Charlotte Douglas
Tue 10/6
6:35 pm-10:10 pm
1 stop4h 35m
$409
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Thu 7/9
4:14 pm-11:58 pm
1 stop6h 44m
Charlotte Douglas
Tue 7/14
9:42 am-12:42 pm
1 stop4h 00m
$412
Quickest round-trip
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Mon 6/29
5:15 pm-9:50 pm
1 stop3h 35m
Charlotte Douglas
Wed 7/1
7:05 pm-10:00 pm
1 stop3h 55m
$415
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Wed 7/8
4:47 pm-9:57 pm
1 stop4h 10m
Charlotte Douglas
Mon 7/13
6:00 am-8:39 am
1 stop3h 39m
$422
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 8/21
5:34 am-11:03 am
1 stop4h 29m
Charlotte Douglas
Sun 8/23
7:54 pm-11:53 pm
1 stop4h 59m
$427
MilwaukeeCharlotte
MKE - CLT
MKECLT
Milwaukee-Mitchell
Fri 11/6
2:45 pm-8:18 pm
1 stop4h 33m
Charlotte Douglas
Sun 11/8
9:35 am-12:27 pm
1 stop3h 52m
$437
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Milwaukee with our price prediction graph.
MKE-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to Spartanburg
MKE-SB1
MKE-CLT
What is the cheapest time of day to fly from MKE to SB1?
Find hourly flight availability from Milwaukee to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 8, 2026.
One of the essential ways to save on airfare from Milwaukee to Spartanburg is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.
Weekly flight availability from Milwaukee to Spartanburg
Explore weekly flight availability from Milwaukee to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 8, 2026.
The most flights from MKE to SB1 are scheduled on a Monday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Milwaukee to Spartanburg?
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated June 8, 2026.
See what other customers who have flown with Southwest and American Airlines from Milwaukee to Spartanburg have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to Spartanburg
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Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
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Milwaukee and Spartanburg flights
Browse other Milwaukee and Spartanburg flight options. Last updated on June 8, 2026.
Other flights from Milwaukee
Browse through other flights departing from Milwaukee. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
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Milwaukee to Spartanburg flights
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Top 4 airlines flying from Milwaukee to Spartanburg
Discover the top 4 airlines that operate flights from Milwaukee to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$370 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$227 | Average$332 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$294 | Average$422 | FlexibilityNo cancel fee | On-time63% |