$61+ Cheap flights from Manchester, NH (MHT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — CHS
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Manchester to South Carolina with Cheapflights
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Cheapest flights from Manchester to South CarolinaExplore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 9/269:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/169:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/239:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 9/199:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/239:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$128
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/309:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$132
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 5/2010:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/169:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$138
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 8/2610:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$144
This Breeze Airways deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Fri 10/212:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:36 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Fri 8/282:46 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Fri 11/1312:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$188
Best flights from Manchester to South CarolinaDiscover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:51 am
MHT
- CHS
1 stop11h 38m
Breeze Airways
Wed 5/1310:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$189
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:45 pm
MHT
- CHS
1 stop4h 40m
Southwest
Sat 5/167:00 am
CHS
- MHT
1 stop4h 50m
Southwest
Deal found 4/23![Southwest logo]()
$255
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:25 am
MHT
- CHS
1 stop5h 00m
United Airlines
Wed 9/237:52 pm
CHS
- MHT
1 stop4h 04m
United Airlines
Deal found 4/25![United Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:44 am
MHT
- SAV
2 stops6h 53m
American Airlines
Thu 5/287:30 pm
SAV
- MHT
1 stop4h 21m
American Airlines
Deal found 4/28![American Airlines logo]()
$332
This Breeze Airways deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:09 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Mon 5/1112:19 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$288
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:31 pm
MHT
- CHS
1 stop4h 28m
United Airlines
Sat 5/232:47 pm
CHS
- MHT
1 stop4h 15m
United Airlines
Deal found 4/25![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:10 pm
MHT
- SAV
1 stop6h 55m
Southwest
Sat 5/237:00 pm
SAV
- MHT
1 stop4h 05m
Southwest
Deal found 4/23![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:36 pm
MHT
- SAV
2 stops9h 22m
United Airlines
Sat 5/2312:10 pm
SAV
- MHT
1 stop6h 52m
United Airlines
Deal found 4/23![United Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:11 pm
MHT
- SAV
1 stop4h 33m
American Airlines
Wed 9/1611:17 am
SAV
- MHT
1 stop5h 47m
American Airlines
Deal found 4/23![American Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:25 am
MHT
- CHS
1 stop5h 00m
United Airlines
Sat 9/198:55 am
CHS
- MHT
2 stops10h 08m
United Airlines
Deal found 4/26![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:44 am
MHT
- GSP
2 stops6h 35m
American Airlines
Wed 5/205:20 am
GSP
- MHT
2 stops6h 16m
American Airlines
Deal found 4/23![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:55 pm
MHT
- MYR
1 stop5h 15m
Southwest
Tue 7/147:05 pm
MYR
- MHT
1 stop3h 40m
Southwest
Deal found 4/27![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:25 am
MHT
- CHS
1 stop5h 00m
United Airlines
Wed 9/210:00 am
CHS
- MHT
1 stop4h 08m
United Airlines
Deal found 4/23![United Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:25 am
MHT
- MYR
1 stop7h 00m
Southwest
Fri 6/128:10 pm
MYR
- MHT
1 stop3h 55m
Southwest
Deal found 4/27![Southwest logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:38 am
MHT
- HHH
1 stop5h 32m
American Airlines
Tue 6/210:57 am
HHH
- MHT
1 stop5h 42m
American Airlines
Deal found 4/26![American Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:50 am
MHT
- CHS
1 stop6h 35m
Southwest
Wed 6/101:50 pm
CHS
- MHT
2 stops7h 25m
Southwest
Deal found 4/24![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:25 am
MHT
- GSP
2 stops11h 52m
United Airlines
Tue 9/227:51 pm
GSP
- MHT
1 stop4h 05m
United Airlines
Deal found 4/26![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:50 am
MHT
- CHS
2 stops10h 35m
Southwest
Wed 9/1610:45 am
CHS
- MHT
2 stops10h 25m
Southwest
Deal found 4/25![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:37 pm
MHT
- GSP
2 stops8h 52m
United Airlines
Thu 5/286:30 am
GSP
- MHT
2 stops7h 32m
United Airlines
Deal found 4/25![United Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:38 am
MHT
- CAE
1 stop5h 06m
American Airlines
Sat 7/256:39 pm
CAE
- MHT
1 stop4h 53m
American Airlines
Deal found 4/24![American Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:30 pm
MHT
- CLT
1 stop5h 10m
Southwest
Mon 8/3110:35 am
CLT
- MHT
2 stops7h 10m
Southwest
Deal found 4/23![Southwest logo]()
$394
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:21 pm
MHT
- CAE
1 stop6h 34m
American Airlines
Wed 6/36:39 pm
CAE
- MHT
1 stop4h 55m
American Airlines
Deal found 4/23![American Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:25 am
MHT
- SAV
1 stop5h 22m
United Airlines
Wed 8/267:15 pm
SAV
- MHT
1 stop4h 41m
United Airlines
Deal found 4/27![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:40 am
MHT
- CLT
1 stop7h 15m
Southwest
Tue 6/96:30 pm
CLT
- MHT
1 stop4h 15m
Southwest
Deal found 4/27![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:38 am
MHT
- HHH
1 stop6h 48m
American Airlines
Mon 6/85:21 pm
HHH
- MHT
1 stop5h 35m
American Airlines
Deal found 4/24![American Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:25 am
MHT
- GSP
1 stop4h 54m
United Airlines
Wed 9/27:51 pm
GSP
- MHT
1 stop4h 05m
United Airlines
Deal found 4/25![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:45 am
MHT
- CLT
1 stop4h 15m
Southwest
Wed 7/13:10 pm
CLT
- MHT
1 stop6h 05m
Southwest
Deal found 4/26![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:37 pm
MHT
- CHS
2 stops9h 19m
United Airlines
Sat 5/306:00 am
CHS
- MHT
2 stops8h 02m
United Airlines
Deal found 4/27![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:25 am
MHT
- MYR
2 stops10h 20m
Southwest
Sun 6/146:30 am
MYR
- MHT
2 stops8h 30m
Southwest
Deal found 4/26![Southwest logo]()
$399
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
MHT
- HHH
2 stops9h 02m
American Airlines
Mon 6/155:21 pm
HHH
- MHT
1 stop5h 35m
American Airlines
Deal found 4/24![American Airlines logo]()
$492
Last-minute flights from Manchester to South CarolinaDiscover last-minute flight deals from Manchester to South Carolina. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to South Carolina. Data last updated April 28, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:50 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Fri 6/123:10 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:50 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Fri 5/2912:19 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:09 pm
MHT
- CLT
1 stop13h 01m
Multiple Airlines
Tue 5/127:58 pm
CLT
- MHT
2 stops16h 41m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$239
This Super.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 5/99:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$147
This Breeze Airways deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 5/1310:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 5/169:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$167
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 5/2010:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$137
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 5/239:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:09 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Mon 6/112:19 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:09 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Fri 5/2912:19 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$238
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 5/309:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$151
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 6/69:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$155
One-way flights from Manchester to South CarolinaSearch for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$61
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$64
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$74
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$81
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:09 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:09 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$89
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$93
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$94
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:13 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$94
This Super.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$95
This Booking.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$96
Find flight deals from Manchester to South Carolina
Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $77 (Kiwi.com) |
One-way from | $61 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $320 |
Good round-trip deal | $167 or less |
Good one-way deal | $91 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Sat 5/9
9:51 am-9:29 pm
1 stop11h 38m
Charleston
Wed 5/13
10:18 am-12:39 pm
Nonstop2h 21m
$189
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 5/13
3:45 pm-8:25 pm
1 stop4h 40m
Charleston
Sat 5/16
7:00 am-11:50 am
1 stop4h 50m
$255
Quickest round-trip
ManchesterMyrtle Beach
MHT - MYR
MHTMYR
Manchester
Fri 5/8
3:09 pm-5:34 pm
Nonstop2h 25m
Myrtle Beach Intl
Mon 5/11
12:19 pm-2:29 pm
Nonstop2h 10m
$288
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 9/16
9:25 am-2:25 pm
1 stop5h 00m
Charleston
Wed 9/23
7:52 pm-11:56 pm
1 stop4h 04m
$307
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Sun 5/17
7:31 pm-11:59 pm
1 stop4h 28m
Charleston
Sat 5/23
2:47 pm-7:02 pm
1 stop4h 15m
$307
ManchesterSavannah
MHT - SAV
MHTSAV
Manchester
Sat 5/16
2:36 pm-11:58 pm
2 stops9h 22m
Savannah/Hilton Head
Sat 5/23
12:10 pm-7:02 pm
1 stop6h 52m
$311
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 9/16
9:25 am-2:25 pm
1 stop5h 00m
Charleston
Sat 9/19
8:55 am-7:03 pm
2 stops10h 08m
$312
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Tue 9/1
9:25 am-2:25 pm
1 stop5h 00m
Charleston
Wed 9/2
10:00 am-2:08 pm
1 stop4h 08m
$322
ManchesterSavannah
MHT - SAV
MHTSAV
Manchester
Sat 5/16
2:10 pm-9:05 pm
1 stop6h 55m
Savannah/Hilton Head
Sat 5/23
7:00 pm-11:05 pm
1 stop4h 05m
$325
ManchesterSavannah
MHT - SAV
MHTSAV
Manchester
Wed 5/20
5:44 am-12:37 pm
2 stops6h 53m
Savannah/Hilton Head
Thu 5/28
7:30 pm-11:51 pm
1 stop4h 21m
$332
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Manchester to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
MHT-CHS
MHT-MYR
MHT-CLT
MHT-SAV
MHT-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to South Carolina
MHT-USSC
MHT-CHS
MHT-MYR
MHT-CLT
MHT-SAV
How far ahead should I book a flight from Manchester, New Hampshire to South Carolina?
To ensure you get the cheapest price possible for a flight from Manchester, New Hampshire to South Carolina, you should look to book at least 24 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Manchester, New Hampshire to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Manchester, New Hampshire to South Carolina (average of $27). Flying from Manchester, New Hampshire to South Carolina in April is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MHT to SC?
Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 28, 2026.
It’s optimal to fly from Manchester, New Hampshire to South Carolina in the evening. By choosing this option you can save up to 59% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Manchester, New Hampshire to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 28, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andAvelo Airlines from Manchester to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Avelo Airlines
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.6
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Manchester to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Manchester to South Carolina by cabin class
Find flights from Manchester to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Manchester and South Carolina flights
Browse other Manchester and South Carolina flight options. Last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Manchester to South Carolina flights
Consider these flights traveling from Manchester to South Carolina.
Top 6 airlines flying from Manchester to South Carolina
Discover the top 6 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$98 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$81 | Average$205 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$87 | Average$166 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$150 | Average$349 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$198 | Average$399 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$247 | Average$442 | FlexibilityNo cancel fee | On-time63% |