$69+ Cheap flights from Manchester, NH (MHT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — CHS
Sep 3 — Sep 101
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Manchester to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Manchester to South CarolinaExplore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:18 pm -
Nonstop2h 44m
Sat 11/149:18 am -
Nonstop2h 20m
Deal found 7/31![Breeze Airways logo]()
$112
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:29 pm -
Nonstop2h 35m
Wed 9/169:18 am -
Nonstop2h 20m
Deal found 8/3![Breeze Airways logo]()
$118
This Priceline deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:18 pm -
Nonstop2h 44m
Sat 9/269:18 am -
Nonstop2h 20m
Deal found 8/4![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:18 pm -
Nonstop2h 44m
Sat 11/79:18 am -
Nonstop2h 20m
Deal found 7/31![Breeze Airways logo]()
$127
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:18 pm -
Nonstop2h 44m
Wed 11/119:18 am -
Nonstop2h 20m
Deal found 7/30![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:18 pm -
Nonstop2h 44m
Wed 10/219:18 am -
Nonstop2h 20m
Deal found 8/3![Breeze Airways logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:18 pm -
Nonstop2h 44m
Wed 11/49:18 am -
Nonstop2h 20m
Deal found 7/30![Breeze Airways logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:49 pm -
Nonstop2h 35m
Sat 9/129:18 am -
Nonstop2h 20m
Deal found 7/30![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:18 pm -
Nonstop2h 44m
Sat 9/269:18 am -
Nonstop2h 20m
Deal found 7/31![Breeze Airways logo]()
$138
This Breeze Airways deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:36 pm -
Nonstop2h 25m
Mon 8/312:46 pm -
Nonstop2h 10m
Deal found 8/1![Breeze Airways logo]()
$228
This CheapOair deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:14 pm -
Nonstop2h 18m
Fri 11/612:24 pm -
Nonstop2h 10m
Deal found 8/1![Breeze Airways logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:36 pm -
Nonstop2h 25m
Mon 8/312:46 pm -
Nonstop2h 10m
Deal found 8/2![Breeze Airways logo]()
$247
Best flights from Manchester to South CarolinaDiscover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
Discover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:18 pm -
Nonstop2h 44m
Wed 10/79:18 am -
Nonstop2h 20m
Deal found 8/4![Breeze Airways logo]()
$178
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:25 pm -
1 stop4h 05m
Wed 10/216:10 pm -
1 stop4h 30m
Deal found 7/30![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:25 am -
1 stop4h 54m
Thu 8/277:47 pm -
1 stop4h 12m
Deal found 7/30![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:40 am -
1 stop6h 37m
Sun 10/45:00 am -
1 stop4h 31m
Deal found 7/31![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:10 pm -
1 stop5h 35m
Sat 11/78:25 am -
1 stop3h 55m
Deal found 7/30![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:50 pm -
2 stops9h 09m
Wed 10/2111:05 am -
2 stops7h 56m
Deal found 7/30![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:39 pm -
1 stop5h 13m
Wed 11/112:40 pm -
1 stop7h 05m
Deal found 7/30![American Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:45 am -
2 stops11h 25m
Tue 10/208:20 am -
1 stop3h 55m
Deal found 7/30![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:25 am -
1 stop4h 54m
Sun 9/67:00 am -
2 stops7h 08m
Deal found 8/4![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:40 am -
1 stop4h 20m
Fri 9/118:10 am -
2 stops9h 35m
Deal found 8/4![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:25 am -
2 stops10h 20m
Sat 9/57:00 am -
2 stops7h 08m
Deal found 8/1![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:33 am -
1 stop6h 53m
Tue 8/186:00 am -
1 stop5h 39m
Deal found 8/2![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:05 am -
2 stops11h 05m
Tue 9/110:45 am -
2 stops10h 25m
Deal found 8/3![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:25 am -
2 stops11h 42m
Mon 8/313:01 pm -
1 stop3h 59m
Deal found 8/4![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:45 am -
2 stops10h 40m
Tue 8/257:50 am -
2 stops9h 45m
Deal found 8/2![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:46 pm -
1 stop4h 49m
Thu 9/109:50 am -
1 stop4h 18m
Deal found 7/31![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:25 pm -
1 stop4h 00m
Mon 11/21:40 pm -
1 stop4h 15m
Deal found 7/31![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am -
1 stop4h 27m
Sun 9/611:40 am -
1 stop5h 02m
Deal found 7/30![American Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:25 am -
2 stops10h 15m
Sat 9/192:54 pm -
1 stop4h 06m
Deal found 8/1![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop4h 27m
Wed 9/92:15 pm -
1 stop7h 40m
Deal found 8/3![American Airlines logo]()
$472
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:55 am -
2 stops6h 55m
Wed 9/1610:45 am -
2 stops10h 30m
Deal found 7/31![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:20 pm -
1 stop4h 20m
Tue 11/178:05 am -
2 stops13h 10m
Deal found 7/31![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:25 am -
1 stop5h 01m
Tue 10/63:03 pm -
1 stop3h 58m
Deal found 8/3![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:50 pm -
1 stop6h 42m
Tue 9/226:00 am -
1 stop5h 32m
Deal found 7/31![American Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:25 am -
1 stop5h 01m
Sat 10/317:54 pm -
1 stop4h 05m
Deal found 8/1![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:55 am -
1 stop3h 45m
Fri 9/181:55 pm -
2 stops8h 35m
Deal found 7/30![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 25m
Mon 11/212:25 pm -
1 stop5h 20m
Deal found 8/2![American Airlines logo]()
$519
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:40 am -
1 stop5h 05m
Sat 9/128:15 am -
1 stop4h 00m
Deal found 8/3![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:25 am -
2 stops11h 37m
Mon 11/97:54 pm -
1 stop4h 05m
Deal found 8/2![United Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:44 pm -
1 stop6h 10m
Mon 9/145:10 am -
1 stop5h 34m
Deal found 7/30![American Airlines logo]()
$527
Last-minute flights from Manchester to South CarolinaDiscover last-minute flight deals from Manchester to South Carolina. Data last updated August 4, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to South Carolina. Data last updated August 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:36 pm -
Nonstop2h 25m
Mon 8/312:46 pm -
Nonstop2h 10m
Deal found 8/2![Breeze Airways logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:36 pm -
Nonstop2h 25m
Mon 8/312:46 pm -
Nonstop2h 10m
Deal found 8/4![Breeze Airways logo]()
$258
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:12 pm -
1 stop13h 12m
Thu 8/278:30 am -
Nonstop2h 20m
Deal found 7/30![American Airlines logo]()
$250
This Breeze Airways deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:36 pm -
Nonstop2h 25m
Mon 8/312:46 pm -
Nonstop2h 10m
Deal found 8/1![Breeze Airways logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:36 pm -
Nonstop2h 25m
Fri 9/42:46 pm -
Nonstop2h 10m
Deal found 7/30![Breeze Airways logo]()
$248
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:29 pm -
Nonstop2h 35m
Wed 9/169:18 am -
Nonstop2h 20m
Deal found 8/3![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:49 pm -
Nonstop2h 35m
Sat 9/129:18 am -
Nonstop2h 20m
Deal found 7/30![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm -
Nonstop2h 44m
Sat 9/199:18 am -
Nonstop2h 20m
Deal found 8/2![Breeze Airways logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm -
Nonstop2h 44m
Wed 9/239:18 am -
Nonstop2h 20m
Deal found 8/1![Breeze Airways logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:18 pm -
Nonstop2h 44m
Sat 9/269:18 am -
Nonstop2h 20m
Deal found 7/31![Breeze Airways logo]()
$138
This Priceline deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:18 pm -
Nonstop2h 44m
Sat 9/269:18 am -
Nonstop2h 20m
Deal found 8/4![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:14 pm -
Nonstop2h 18m
Fri 10/212:24 pm -
Nonstop2h 10m
Deal found 7/30![Breeze Airways logo]()
$277
One-way flights from Manchester to South CarolinaSearch for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
Search for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:18 pm -
Nonstop2h 44m
Deal found 8/4![Breeze Airways logo]()
$69
This CheapOair deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:18 pm -
Nonstop2h 44m
Deal found 8/3![Breeze Airways logo]()
$71
This CheapOair deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:18 pm -
Nonstop2h 44m
Deal found 8/4![Breeze Airways logo]()
$81
This CheapOair deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:49 pm -
Nonstop2h 35m
Deal found 8/1![Breeze Airways logo]()
$93
This CheapOair deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:23 pm -
Nonstop2h 44m
Deal found 8/3![Breeze Airways logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:14 pm -
Nonstop2h 18m
Deal found 8/1![Breeze Airways logo]()
$99
This CheapOair deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:14 pm -
Nonstop2h 18m
Deal found 8/1![Breeze Airways logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:51 am -
1 stop11h 38m
Deal found 8/1![Breeze Airways logo]()
$117
This CheapOair deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:49 pm -
Nonstop2h 35m
Deal found 8/2![Breeze Airways logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:36 pm -
Nonstop2h 25m
Deal found 8/4![Breeze Airways logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:36 pm -
Nonstop2h 25m
Deal found 8/2![Breeze Airways logo]()
$129
This CheapOair deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:18 pm -
Nonstop2h 44m
Deal found 8/1![Breeze Airways logo]()
$136
Find flight deals from Manchester to South Carolina
Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated August 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $87 (Kiwi.com) |
One-way from | $68 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $275 |
Good round-trip deal | $158 or less |
Good one-way deal | $118 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Sat 10/3
12:18 pm-3:02 pm
Nonstop2h 44m
Charleston
Wed 10/7
9:18 am-11:38 am
Nonstop2h 20m
$178
ManchesterCharlotte
MHT - CLT
MHTCLT
Manchester
Mon 10/19
5:25 pm-9:30 pm
1 stop4h 05m
Charlotte Douglas
Wed 10/21
6:10 pm-10:40 pm
1 stop4h 30m
$321
ManchesterGreenville
MHT - GSP
MHTGSP
Manchester
Thu 8/27
9:25 am-2:19 pm
1 stop4h 54m
Greenville
Thu 8/27
7:47 pm-11:59 pm
1 stop4h 12m
$325
ManchesterGreenville
MHT - GSP
MHTGSP
Manchester
Tue 11/3
2:10 pm-7:45 pm
1 stop5h 35m
Greenville
Sat 11/7
8:25 am-12:20 pm
1 stop3h 55m
$325
ManchesterCharlotte
MHT - CLT
MHTCLT
Manchester
Tue 10/13
6:45 am-6:10 pm
2 stops11h 25m
Charlotte Douglas
Tue 10/20
8:20 am-12:15 pm
1 stop3h 55m
$326
ManchesterMyrtle Beach
MHT - MYR
MHTMYR
Manchester
Sun 9/6
10:40 am-3:00 pm
1 stop4h 20m
Myrtle Beach Intl
Fri 9/11
8:10 am-5:45 pm
2 stops9h 35m
$330
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 10/14
2:50 pm-11:59 pm
2 stops9h 09m
Charleston
Wed 10/21
11:05 am-7:01 pm
2 stops7h 56m
$335
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Tue 8/25
10:05 am-9:10 pm
2 stops11h 05m
Charleston
Tue 9/1
10:45 am-9:10 pm
2 stops10h 25m
$335
ManchesterMyrtle Beach
MHT - MYR
MHTMYR
Manchester
Sat 8/22
5:45 am-4:25 pm
2 stops10h 40m
Myrtle Beach Intl
Tue 8/25
7:50 am-5:35 pm
2 stops9h 45m
$335
ManchesterColumbia
MHT - CAE
MHTCAE
Manchester
Sun 9/27
5:40 am-12:17 pm
1 stop6h 37m
Columbia Metropolitan
Sun 10/4
5:00 am-9:31 am
1 stop4h 31m
$339
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Manchester to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
MHT-CHS
MHT-MYR
MHT-CLT
MHT-GSP
MHT-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to South Carolina
MHT-USSC
MHT-CHS
MHT-MYR
MHT-CLT
MHT-GSP
What is the cheapest month to book a flight from Manchester, New Hampshire to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to South Carolina (average of $150). Flying from Manchester, New Hampshire to South Carolina in April is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MHT to SC?
Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 4, 2026.
It’s optimal to fly from Manchester, New Hampshire to South Carolina in the evening. By choosing this option you can save up to 43% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Manchester, New Hampshire to South Carolina?
Airfare is below average for this route at the moment.
Manchester, New Hampshire to South Carolina flights typically cost between $138 and $264 in January.The cheapest round-trip price found within the last 5 days was $87 on Breeze Airways (Jan 23-Jan 27).
How far ahead should I book a flight from Manchester, New Hampshire to South Carolina?
To ensure you get the cheapest price possible for a flight from Manchester, New Hampshire to South Carolina, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 4, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andAvelo Airlines from Manchester to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Avelo Airlines
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Crew
8.7
Entertainment
6.7
Food
6.7
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Manchester to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Manchester to South Carolina by cabin class
Find flights from Manchester to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Manchester and South Carolina flights
Browse other Manchester and South Carolina flight options. Last updated on August 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Manchester to South Carolina flights
Consider these flights traveling from Manchester to South Carolina.
Top 5 airlines flying from Manchester to South Carolina
Discover the top 5 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$105 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$88 | Average$226 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$150 | Average$437 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$238 | Average$423 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$261 | Average$450 | FlexibilityNo cancel fee | On-time63% |