$61+ Cheap flights from Manchester, NH (MHT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — CHS
Jul 14 — Jul 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Manchester to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Manchester to South CarolinaExplore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/179:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/179:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/109:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/109:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/179:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$147
This Breeze Airways deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 10/79:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 10/79:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Wed 9/309:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 11/149:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Sat 10/179:18 am
CHS
- MHT
Nonstop2h 20m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$167
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:51 am
MHT
- CHS
1 stop11h 38m
Breeze Airways
Wed 9/29:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Fri 12/1112:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$227
Best flights from Manchester to South CarolinaDiscover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
Discover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:51 am
MHT
- CHS
1 stop11h 38m
Breeze Airways
Sat 8/89:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$233
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:32 pm
MHT
- CAE
1 stop4h 44m
American Airlines
Wed 7/86:38 pm
CAE
- MHT
1 stop4h 59m
American Airlines
Deal found 6/12![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:45 am
MHT
- MYR
1 stop9h 55m
Southwest
Fri 9/118:10 am
MYR
- MHT
2 stops9h 35m
Southwest
Deal found 6/9![Southwest logo]()
$329
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:30 pm
MHT
- CAE
1 stop5h 19m
United Airlines
Mon 11/97:35 pm
CAE
- MHT
1 stop4h 24m
United Airlines
Deal found 6/11![United Airlines logo]()
$389
This Breeze Airways deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Mon 9/2812:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$268
This Breeze Airways deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:51 am
MHT
- CHS
1 stop11h 38m
Breeze Airways
Sat 7/119:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$282
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:32 pm
MHT
- CAE
1 stop4h 44m
American Airlines
Mon 6/296:03 pm
CAE
- MHT
1 stop4h 53m
American Airlines
Deal found 6/10![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:10 pm
MHT
- SAV
1 stop4h 35m
Southwest
Mon 10/261:15 pm
SAV
- MHT
2 stops9h 10m
Southwest
Deal found 6/9![Southwest logo]()
$350
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:46 pm
MHT
- CAE
1 stop4h 21m
United Airlines
Mon 9/217:54 pm
CAE
- MHT
1 stop4h 05m
United Airlines
Deal found 6/9![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:35 am
MHT
- CHS
1 stop4h 20m
Southwest
Wed 7/222:10 pm
CHS
- MHT
2 stops7h 10m
Southwest
Deal found 6/10![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:46 pm
MHT
- CAE
1 stop4h 21m
United Airlines
Mon 8/317:54 pm
CAE
- MHT
1 stop4h 05m
United Airlines
Deal found 6/13![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:35 am
MHT
- CLT
1 stop4h 40m
Southwest
Tue 8/181:30 pm
CLT
- MHT
1 stop4h 05m
Southwest
Deal found 6/11![Southwest logo]()
$360
This Breeze Airways deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Fri 11/2712:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$368
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:25 am
MHT
- HHH
1 stop5h 13m
American Airlines
Sun 9/65:46 pm
HHH
- MHT
1 stop5h 06m
American Airlines
Deal found 6/12![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:25 am
MHT
- CAE
1 stop4h 56m
United Airlines
Tue 9/16:25 am
CAE
- MHT
2 stops12h 35m
United Airlines
Deal found 6/9![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:05 am
MHT
- CLT
2 stops11h 05m
Southwest
Sat 8/298:25 am
CLT
- MHT
1 stop3h 50m
Southwest
Deal found 6/13![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:38 am
MHT
- HHH
1 stop5h 39m
American Airlines
Tue 8/411:47 am
HHH
- MHT
1 stop4h 59m
American Airlines
Deal found 6/11![American Airlines logo]()
$407
This Breeze Airways deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:51 am
MHT
- CHS
1 stop11h 38m
Breeze Airways
Sat 8/19:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$371
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:30 pm
MHT
- SAV
1 stop5h 42m
United Airlines
Wed 10/289:45 am
SAV
- MHT
1 stop5h 18m
United Airlines
Deal found 6/13![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:35 am
MHT
- CLT
1 stop4h 40m
Southwest
Tue 8/116:50 am
CLT
- MHT
2 stops7h 30m
Southwest
Deal found 6/8![Southwest logo]()
$365
This Breeze Airways deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:36 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Mon 8/312:46 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$373
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am
MHT
- SAV
1 stop4h 50m
Southwest
Sun 10/256:40 am
SAV
- MHT
1 stop10h 15m
Southwest
Deal found 6/11![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:25 am
MHT
- CHS
2 stops12h 09m
United Airlines
Sun 8/237:51 pm
CHS
- MHT
1 stop4h 08m
United Airlines
Deal found 6/11![United Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
MHT
- HHH
1 stop4h 27m
American Airlines
Sat 8/293:27 pm
HHH
- MHT
1 stop6h 29m
American Airlines
Deal found 6/13![American Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:10 am
MHT
- CHS
1 stop4h 20m
Southwest
Sat 7/117:30 pm
CHS
- MHT
1 stop4h 05m
Southwest
Deal found 6/12![Southwest logo]()
$367
This Breeze Airways deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Mon 10/512:24 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$408
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:37 pm
MHT
- SAV
2 stops9h 15m
United Airlines
Fri 8/1412:59 pm
SAV
- MHT
2 stops11h 00m
United Airlines
Deal found 6/10![United Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:09 pm
MHT
- CAE
1 stop11h 43m
American Airlines
Sun 11/227:06 am
CAE
- MHT
1 stop16h 50m
American Airlines
Deal found 6/9![American Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:00 am
MHT
- MYR
1 stop9h 35m
Southwest
Sun 9/277:30 am
MYR
- MHT
1 stop3h 35m
Southwest
Deal found 6/9![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:38 am
MHT
- AGS
1 stop6h 41m
American Airlines
Sat 7/256:31 pm
AGS
- MHT
1 stop4h 20m
American Airlines
Deal found 6/13![American Airlines logo]()
$473
Last-minute flights from Manchester to South CarolinaDiscover last-minute flight deals from Manchester to South Carolina. Data last updated June 14, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to South Carolina. Data last updated June 14, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Fri 6/193:10 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$302
This CheapOair deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 6/2410:18 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/159:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$179
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 7/49:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$201
This Super.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 8/89:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$184
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/159:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$190
This Super.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/229:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$198
This Priceline deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:36 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Mon 7/202:46 pm
MYR
- MHT
Nonstop2h 10m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/229:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 7/299:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Sat 7/259:28 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Wed 8/59:48 am
CHS
- MHT
Nonstop2h 21m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$183
One-way flights from Manchester to South CarolinaSearch for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
Search for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$61
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:29 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$78
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$81
This Breeze Airways deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$84
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$87
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:18 pm
MHT
- CHS
Nonstop2h 44m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$93
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:19 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$95
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:49 pm
MHT
- CHS
Nonstop2h 35m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$98
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:36 pm
MHT
- MYR
Nonstop2h 25m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:14 pm
MHT
- MYR
Nonstop2h 18m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$128
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:35 am
MHT
- MYR
1 stop4h 30m
Southwest
Deal found 6/11![Southwest logo]()
$132
Find flight deals from Manchester to South Carolina
Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated June 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Kiwi.com) |
One-way from | $61 (CheapOair) |
Popular in | December |
Cheapest in | January |
Average price | $273 |
Good round-trip deal | $154 or less |
Good one-way deal | $103 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 7/8
9:51 am-9:29 pm
1 stop11h 38m
Charleston
Sat 8/8
9:28 am-11:49 am
Nonstop2h 21m
$233
Quickest round-trip
ManchesterMyrtle Beach
MHT - MYR
MHTMYR
Manchester
Mon 9/21
3:14 pm-5:32 pm
Nonstop2h 18m
Myrtle Beach Intl
Mon 9/28
12:24 pm-2:34 pm
Nonstop2h 10m
$268
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Wed 7/1
9:51 am-9:29 pm
1 stop11h 38m
Charleston
Sat 7/11
9:28 am-11:49 am
Nonstop2h 21m
$282
ManchesterColumbia
MHT - CAE
MHTCAE
Manchester
Wed 7/1
5:32 pm-10:16 pm
1 stop4h 44m
Columbia Metropolitan
Wed 7/8
6:38 pm-11:37 pm
1 stop4h 59m
$324
ManchesterMyrtle Beach
MHT - MYR
MHTMYR
Manchester
Tue 9/8
7:45 am-5:40 pm
1 stop9h 55m
Myrtle Beach Intl
Fri 9/11
8:10 am-5:45 pm
2 stops9h 35m
$329
ManchesterColumbia
MHT - CAE
MHTCAE
Manchester
Thu 6/25
5:32 pm-10:16 pm
1 stop4h 44m
Columbia Metropolitan
Mon 6/29
6:03 pm-10:56 pm
1 stop4h 53m
$339
ManchesterSavannah
MHT - SAV
MHTSAV
Manchester
Fri 10/23
2:10 pm-6:45 pm
1 stop4h 35m
Savannah/Hilton Head
Mon 10/26
1:15 pm-10:25 pm
2 stops9h 10m
$350
ManchesterCharleston
MHT - CHS
MHTCHS
Manchester
Sat 7/18
5:35 am-9:55 am
1 stop4h 20m
Charleston
Wed 7/22
2:10 pm-9:20 pm
2 stops7h 10m
$356
ManchesterCharlotte
MHT - CLT
MHTCLT
Manchester
Tue 8/11
5:35 am-10:15 am
1 stop4h 40m
Charlotte Douglas
Tue 8/18
1:30 pm-5:35 pm
1 stop4h 05m
$360
ManchesterCharlotte
MHT - CLT
MHTCLT
Manchester
Wed 8/26
10:05 am-9:10 pm
2 stops11h 05m
Charlotte Douglas
Sat 8/29
8:25 am-12:15 pm
1 stop3h 50m
$364
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Manchester to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
MHT-CHS
MHT-MYR
MHT-CAE
MHT-SAV
MHT-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to South Carolina
MHT-USSC
MHT-CHS
MHT-MYR
MHT-CAE
MHT-SAV
What is the cheapest month to book a flight from Manchester, New Hampshire to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Manchester, New Hampshire to South Carolina (average of $27). Flying from Manchester, New Hampshire to South Carolina in April is currently the most expensive (average of $663). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MHT to SC?
Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 14, 2026.
It’s optimal to fly from Manchester, New Hampshire to South Carolina in the evening. By choosing this option you can save up to 40% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Manchester, New Hampshire to South Carolina?
How far ahead should I book a flight from Manchester, New Hampshire to South Carolina?
To ensure you get the cheapest price possible for a flight from Manchester, New Hampshire to South Carolina, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 14, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andAvelo Airlines from Manchester to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Avelo Airlines
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Entertainment
6.6
Food
6.7
Boarding
8.3
Overall
8.2
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Manchester to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Manchester to South Carolina by cabin class
Find flights from Manchester to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Manchester and South Carolina flights
Browse other Manchester and South Carolina flight options. Last updated on June 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Manchester to South Carolina flights
Consider these flights traveling from Manchester to South Carolina.
Top 5 airlines flying from Manchester to South Carolina
Discover the top 5 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$98 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$85 | Average$215 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$150 | Average$421 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$227 | Average$405 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$447 | FlexibilityNo cancel fee | On-time63% |