How long is the flight from Manchester, New Hampshire to Florence, South Carolina?

American Airlines can get you from Manchester, New Hampshire to Florence, South Carolina in just under 4h 48m. Your travel time can differ by up to . Manchester, New Hampshire and Florence, South Carolina are separated by a distance of 751 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from MHT to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Manchester, New Hampshire to Florence, South Carolina as you normally would.

Most accurate provider : When it comes to deals on Manchester, New Hampshire-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Manchester, New Hampshire-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Manchester, New Hampshire-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Manchester to Florence that include hotel bookings?

Yes. In addition to deals on Manchester to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Manchester to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Florence.

Can I find deals for business class flights from Manchester to Florence?

Yes. Cheapflights offers flight deals from Manchester to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$695+ Cheap Flights from Manchester, NH to Florence, SC

Q: E

Most trusted provider : When it comes to deals on Manchester, New Hampshire-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Q: Can I find deals for flights from Manchester to Florence that include hotel bookings?

Yes. In addition to deals on Manchester to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

Q: How can I find direct flights from Manchester to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Florence.

Q: Can I find deals for business class flights from Manchester to Florence?

Yes. Cheapflights offers flight deals from Manchester to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Manchester to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Manchester to Florence

Cheapest

Best

Cheapest flights from Manchester to Florence
Explore the most affordable flight options available from Manchester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.

Sat 12/267:09 pm -

1 stop4h 48m

Sat 1/93:58 pm -

1 stop6h 06m

Deal found 9/13

$695

Find flight deals from Manchester to Florence

Most accurate provider	Expedia 1 star
Most trusted provider	Expedia 3 stars
Round-trip from	$695 (American Airlines)
Popular in	May
Cheapest in	March
Average price	$623

Provider with most accurate pricing for Manchester-Florence flight deals.

Search Deals

Provider most trusted by Cheapflights users for Manchester-Florence flights.

Search Deals

From Manchester to Florence

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($58 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

ManchesterFlorence

MHT Manchester - FLO Florence

MHTFLO

Manchester

Sat 12/26

7:09 pm-11:57 pm

1 stop4h 48m

Florence

Sat 1/9

3:58 pm-10:04 pm

1 stop6h 06m

$695

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Sorted by cheapest first

Most accurate provider: When it comes to deals on Manchester, New Hampshire-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Manchester, New Hampshire-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Manchester, New Hampshire-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Manchester with our price prediction graph.

MHT-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Manchester, New Hampshire to Florence, South Carolina?
American Airlines can get you from Manchester, New Hampshire to Florence, South Carolina in just under 4h 48m. Your travel time can differ by up to . Manchester, New Hampshire and Florence, South Carolina are separated by a distance of 751 mi.
Can I find deals for flights from Manchester to Florence that include hotel bookings?
Yes. In addition to deals on Manchester to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Manchester to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Florence.
Can I find deals for business class flights from Manchester to Florence?
Yes. Cheapflights offers flight deals from Manchester to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Sumter

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Flights by cabin class

Florence flight routes

Other flight options

Other flights from Manchester

Popular flights

Alternative routes for Manchester to Florence

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$695+ Cheap flights from Manchester, NH to Florence, SC (MHT - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Manchester to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Manchester to Florence

Cheapest flights from Manchester to FlorenceExplore the most affordable flight options available from Manchester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.

Explore the most affordable flight options available from Manchester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.

Best flights from Manchester to FlorenceDiscover carefully curated flight deals from Manchester to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.

Discover carefully curated flight deals from Manchester to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.

Find flight deals from Manchester to Florence

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Florence that are best for you.

Best time to book a flight from Manchester to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Manchester with our price prediction graph.

Related info for your journey

How long is the flight from Manchester, New Hampshire to Florence, South Carolina?

Can I find deals for flights from Manchester to Florence that include hotel bookings?

How can I find direct flights from Manchester to Florence?

Can I find deals for business class flights from Manchester to Florence?

Traveling to a place near Florence?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Florence

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Manchester to Florence by cabin class

Find flights from Manchester to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Other flights to Florence

Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.

Manchester and Florence flights

Browse other Manchester and Florence flight options. Last updated on September 16, 2026.

Other flights from Manchester

Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Manchester to Florence
Explore the most affordable flight options available from Manchester to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.

Best flights from Manchester to Florence
Discover carefully curated flight deals from Manchester to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.