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South Carolina

$34+ Cheap flights from Cleveland (CLE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
Apr 27 — May 41
Mon 4/27
Mon 5/4
1 adult, Economy
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Cheap flight deals from Cleveland to South Carolina

Cheapest flights from Cleveland to South Carolina
Explore the most affordable flight options available from Cleveland to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2026.

This Frontier deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/193:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Thu 4/235:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/28$68
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Thu 4/235:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/25$76
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Mon 4/275:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/23$81
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Thu 4/235:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/27$83
This Priceline deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Sun 5/35:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/27$87
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Thu 4/235:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/25$88
This Priceline deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:00 pm
CLE
-
MYR
Nonstop1h 46m
Frontier
Thu 5/283:31 pm
MYR
-
CLE
Nonstop1h 52m
Frontier
Deal found 3/25$94
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Sun 4/195:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/25$95
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Fri 4/175:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/25$96
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:00 pm
CLE
-
MYR
Nonstop1h 44m
Frontier
Mon 4/205:29 pm
MYR
-
CLE
Nonstop1h 53m
Frontier
Deal found 3/27$98
This Super.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:00 pm
CLE
-
MYR
Nonstop1h 46m
Frontier
Thu 5/143:31 pm
MYR
-
CLE
Nonstop1h 52m
Frontier
Deal found 3/23$99
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:46 pm
CLE
-
CHS
1 stop25h 39m
Multiple Airlines
Sat 5/212:05 pm
CHS
-
CLE
1 stop12h 38m
Multiple Airlines
Deal found 3/27$180

Find flight deals from Cleveland to South Carolina

Keep the following information in mind while searching for Cleveland to South Carolina flight deals. Data was last updated March 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$67
(Super.com)

One-way from

$34
(CheapOair)

Popular in

January

Cheapest in

August

Average price

$350

Good round-trip deal

$103 or less

Good one-way deal

$79 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Myrtle Beach Intl flights.
Search Deals
From Cleveland Hopkins Intl to South Carolina
Search Deals
One-way flight from Cleveland Hopkins Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Cleveland Hopkins Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Cleveland Hopkins Intl to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Cleveland to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandColumbia

CLE - CAE

CLECAE

Cleveland Hopkins Intl

Wed 6/3

4:28 pm-10:47 pm

1 stop6h 19m

Columbia Metropolitan

Tue 6/9

5:35 am-11:33 am

1 stop5h 58m

$271

ClevelandColumbia

CLE - CAE

CLECAE

Cleveland Hopkins Intl

Tue 7/14

7:37 pm-11:49 pm

1 stop4h 12m

Columbia Metropolitan

Tue 7/28

7:05 am-12:14 pm

1 stop5h 09m

$271

ClevelandGreenville

CLE - GSP

CLEGSP

Cleveland Hopkins Intl

Tue 5/5

5:50 am-10:20 am

1 stop4h 30m

Greenville

Fri 5/8

6:00 am-12:16 pm

1 stop6h 16m

$272

ClevelandGreenville

CLE - GSP

CLEGSP

Cleveland Hopkins Intl

Thu 5/14

6:35 am-10:55 am

1 stop4h 20m

Greenville

Mon 5/18

3:59 pm-10:18 pm

1 stop6h 19m

$273

ClevelandSavannah

CLE - SAV

CLESAV

Cleveland Hopkins Intl

Sat 4/18

6:05 am-4:40 pm

2 stops10h 35m

Savannah/Hilton Head

Wed 4/22

6:40 am-5:25 pm

2 stops10h 45m

$274

ClevelandCharleston

CLE - CHS

CLECHS

Cleveland Hopkins Intl

Tue 5/5

9:01 am-3:37 pm

1 stop6h 36m

Charleston

Wed 5/6

5:55 pm-11:34 pm

1 stop5h 39m

$284

ClevelandCharleston

CLE - CHS

CLECHS

Cleveland Hopkins Intl

Mon 5/11

12:40 pm-8:50 pm

2 stops8h 10m

Charleston

Tue 5/12

6:20 pm-10:15 pm

1 stop3h 55m

$296

ClevelandGreenville

CLE - GSP

CLEGSP

Cleveland Hopkins Intl

Tue 5/5

2:45 pm-9:40 pm

2 stops6h 55m

Greenville

Fri 5/8

6:25 am-3:05 pm

2 stops8h 40m

$297

ClevelandCharlotte

CLE - CLT

CLECLT

Cleveland Hopkins Intl

Fri 5/29

12:55 pm-9:40 pm

2 stops8h 45m

Charlotte Douglas

Tue 6/2

7:35 am-5:00 pm

2 stops9h 25m

$301

ClevelandSavannah

CLE - SAV

CLESAV

Cleveland Hopkins Intl

Fri 5/8

4:15 pm-9:13 pm

1 stop4h 58m

Savannah/Hilton Head

Mon 5/11

8:08 am-1:19 pm

1 stop5h 11m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Cleveland to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to South Carolina

What is the cheapest month to book a flight from Cleveland to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Cleveland to South Carolina (average of $47). Flying from Cleveland to South Carolina in November is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to SC?

Find hourly flight availability from Cleveland to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2026.

A simple way to save on the total cost of your ticket is to fly from Cleveland to South Carolina in the afternoon. If you’re flexible enough to do this you can expect to save up to 56% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Cleveland to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Cleveland to South Carolina. Price data was last updated on August 3, 2025.

Travelers seeking maximum savings on their Cleveland to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Cleveland to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 28, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Cleveland to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,333 reviews
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,357 reviews
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,520 reviews
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Spirit Airlines
6.3
Okay
8,552 reviews
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Frontier
5.7
Fair
3,013 reviews
Southwest
8.0
Very good
4,333 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to South Carolina?

    Cleveland Hopkins Intl (CLE), located 10.1 mi from the city center, is the airport you fly out of when you book flights from Cleveland to South Carolina.

  • How popular is this Cleveland to South Carolina flight route?

    Within the past month, 1 users have taken a look at flights from Cleveland Hopkins Intl to South Carolina.

  • How long is the flight from Cleveland to South Carolina?

    Departing from Cleveland to South Carolina will take you 4h 48m. Cleveland and South Carolina are separated by a distance of 642 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Cleveland to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $125. Users have also found prices from $131 and $132 on Volaris and Delta, respectively.

  • What are the most popular routes from Cleveland to South Carolina?

    The most popular route from Cleveland to South Carolina is Cleveland Hopkins Intl - Charlotte Douglas. You may also consider Cleveland Hopkins Intl - Myrtle Beach Intl or Cleveland Hopkins Intl - Charleston.

  • Can I find deals for flights from Cleveland to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cleveland to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to South Carolina.

  • Can I find deals for business class flights from Cleveland to South Carolina?

    Yes. Cheapflights offers flight deals from Cleveland to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Cleveland to South Carolina (average of $47). Flying from Cleveland to South Carolina in November is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cleveland to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Cleveland to South Carolina

Discover the top 6 airlines that operate flights from Cleveland to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$57Average$135FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$65Average$124FlexibilityNo cancel feeOn-time65%
DeltaCheapest$100Average$299FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$153Average$353FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$196Average$369FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$208Average$346FlexibilityNo cancel feeOn-time71%

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