In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Jacksonville, North Carolina to South America?

Most travelers choose Jacksonville Albert J Ellis - Buenos Aires Ministro Pistarini, Jacksonville Albert J Ellis - Bogotá El Dorado or Jacksonville Albert J Ellis - Cartagena Rafael Nunez when deciding on the best route from Jacksonville, North Carolina to South America.

What is the cheapest time of day to fly from OAJ to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Jacksonville, North Carolina to South America as you normally would.

What airport do you fly from for flights from Jacksonville to South America?

Most people fly from Jacksonville Albert J Ellis (OAJ) if they book a flight from Jacksonville to South America. Jacksonville Albert J Ellis is conveniently located just 11.3 mi from Jacksonville’s city center.

Can I find deals for flights from Jacksonville to South America that include hotel bookings?

Yes. In addition to deals on Jacksonville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Jacksonville to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to South America.

Can I find deals for business class flights from Jacksonville to South America?

Yes. Cheapflights offers flight deals from Jacksonville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Flights from Jacksonville, NC to South America

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Jacksonville to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with American Airlines from Jacksonville to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

American Airlines

7.2

Good

11,054 reviews

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

What airport do you fly from for flights from Jacksonville to South America?
Most people fly from Jacksonville Albert J Ellis (OAJ) if they book a flight from Jacksonville to South America. Jacksonville Albert J Ellis is conveniently located just 11.3 mi from Jacksonville’s city center.
What are the most popular routes from Jacksonville, North Carolina to South America?
Most travelers choose Jacksonville Albert J Ellis - Buenos Aires Ministro Pistarini, Jacksonville Albert J Ellis - Bogotá El Dorado or Jacksonville Albert J Ellis - Cartagena Rafael Nunez when deciding on the best route from Jacksonville, North Carolina to South America.
Can I find deals for flights from Jacksonville to South America that include hotel bookings?
Yes. In addition to deals on Jacksonville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Jacksonville to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to South America.
Can I find deals for business class flights from Jacksonville to South America?
Yes. Cheapflights offers flight deals from Jacksonville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Jacksonville to South America

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$776	Average$2,849	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Find cheap flights from Jacksonville to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with American Airlines from Jacksonville to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Jacksonville to South America?

What are the most popular routes from Jacksonville, North Carolina to South America?

Can I find deals for flights from Jacksonville to South America that include hotel bookings?

How can I find direct flights from Jacksonville to South America?

Can I find deals for business class flights from Jacksonville to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to South America

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Jacksonville to South America by cabin class

Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Jacksonville and South America flights

Browse other Jacksonville and South America flight options. Last updated on December 24, 2025.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2025

Fly to South America countries

Consider these flights traveling to countries located in South America.

Jacksonville to South America flights

Consider these flights traveling from Jacksonville to South America.

Top airline flying from Jacksonville to South America

100% Free

Book with Flexibility

Travel Smart

Cheap flights from Jacksonville, NC (OAJ) to South America

Find cheap flights from Jacksonville to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with American Airlines from Jacksonville to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Jacksonville to South America?

What are the most popular routes from Jacksonville, North Carolina to South America?

Can I find deals for flights from Jacksonville to South America that include hotel bookings?

How can I find direct flights from Jacksonville to South America?

Can I find deals for business class flights from Jacksonville to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Jacksonville to South America

100% Free

Book with Flexibility

Travel Smart