$274+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Santo Domingo
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Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:14 pm -
3 stops23h 58m
Tue 12/13:35 pm -
3 stops22h 09m
Deal found 10/20![Multiple Airlines logo]()
$626
This Trip.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:02 am -
2 stops35h 17m
Sat 11/213:35 pm -
2 stops20h 14m
Deal found 10/18![Multiple Airlines logo]()
$639
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
2 stops24h 35m
Sun 11/156:45 pm -
2 stops45h 10m
Deal found 10/20![Avianca logo]()
$673
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:11 pm -
2 stops17h 55m
Tue 12/13:35 pm -
3 stops22h 09m
Deal found 10/20![Multiple Airlines logo]()
$676
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:15 pm -
2 stops24h 35m
Mon 11/26:45 pm -
2 stops54h 55m
Deal found 10/19![Avianca logo]()
$680
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:44 pm -
2 stops18h 35m
Sat 12/123:35 pm -
3 stops31h 56m
Deal found 10/20![Multiple Airlines logo]()
$691
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:20 pm -
3 stops30h 52m
Tue 11/173:35 pm -
3 stops23h 42m
Deal found 10/21![Multiple Airlines logo]()
$702
This SmartFares deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
2 stops24h 35m
Tue 11/1712:45 pm -
2 stops27h 10m
Deal found 10/21![Avianca logo]()
$704
This Travelocity deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:50 am -
1 stop10h 09m
Fri 12/1112:15 pm -
1 stop13h 18m
Deal found 10/19![Multiple Airlines logo]()
$705
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/217:36 pm -
1 stop26h 28m
Wed 3/38:48 am -
1 stop18h 17m
Deal found 10/22![Copa Airlines logo]()
$554
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:34 am -
3 stops30h 45m
Sat 12/123:35 pm -
3 stops31h 56m
Deal found 10/20![Multiple Airlines logo]()
$699
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:35 pm -
1 stop8h 30m
Sat 12/126:00 am -
1 stop17h 20m
Deal found 10/18![American Airlines logo]()
$742
This JetBlue deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1511:59 pm -
1 stop13h 21m
Tue 2/236:01 am -
1 stop12h 39m
Deal found 10/17![JetBlue logo]()
$837
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/237:55 pm -
1 stop23h 27m
Sat 3/278:40 am -
1 stop12h 48m
Deal found 10/18![Copa Airlines logo]()
$581
This Orbitz deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:50 am -
1 stop10h 09m
Wed 11/2512:45 pm -
2 stops38h 10m
Deal found 10/21![Multiple Airlines logo]()
$810
This JetBlue deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:25 pm -
1 stop9h 57m
Thu 11/52:32 pm -
1 stop12h 02m
Deal found 10/17![JetBlue logo]()
$847
This JetBlue deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/58:00 am -
1 stop12h 47m
Wed 2/174:20 am -
1 stop13h 53m
Deal found 10/19![JetBlue logo]()
$877
This JetBlue deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/318:00 am -
1 stop12h 47m
Sat 2/202:45 pm -
1 stop13h 34m
Deal found 10/19![JetBlue logo]()
$882
This JetBlue deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/28:00 am -
1 stop12h 47m
Mon 2/1511:15 pm -
1 stop14h 53m
Deal found 10/19![JetBlue logo]()
$907
This JetBlue deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/138:10 am -
1 stop12h 47m
Fri 2/196:01 am -
1 stop11h 02m
Deal found 10/17![JetBlue logo]()
$907
This JetBlue deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:00 am -
1 stop12h 47m
Mon 2/1511:15 pm -
1 stop14h 53m
Deal found 10/19![JetBlue logo]()
$907
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated October 22, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:15 pm -
2 stops24h 35m
Mon 11/26:45 pm -
2 stops54h 55m
Deal found 10/19![Avianca logo]()
$680
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:20 pm -
2 stops19h 25m
Sun 11/156:45 pm -
2 stops45h 10m
Deal found 10/21![Multiple Airlines logo]()
$717
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
2 stops24h 35m
Sun 11/156:45 pm -
2 stops45h 10m
Deal found 10/20![Avianca logo]()
$673
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:20 pm -
3 stops30h 52m
Tue 11/173:35 pm -
3 stops23h 42m
Deal found 10/21![Multiple Airlines logo]()
$702
This SmartFares deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
2 stops24h 35m
Tue 11/1712:45 pm -
2 stops27h 10m
Deal found 10/21![Avianca logo]()
$704
This Trip.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:02 am -
2 stops35h 17m
Sat 11/213:35 pm -
2 stops20h 14m
Deal found 10/18![Multiple Airlines logo]()
$639
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:14 pm -
3 stops23h 58m
Tue 12/13:35 pm -
3 stops22h 09m
Deal found 10/20![Multiple Airlines logo]()
$626
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:11 pm -
2 stops17h 55m
Tue 12/13:35 pm -
3 stops22h 09m
Deal found 10/20![Multiple Airlines logo]()
$676
This Travelocity deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:50 am -
1 stop10h 09m
Fri 12/1112:15 pm -
1 stop13h 18m
Deal found 10/19![Multiple Airlines logo]()
$705
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:39 am -
3 stops25h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
3 stops44h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm -
3 stops24h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:57 pm -
3 stops43h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:20 pm -
2 stops14h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:20 pm -
2 stops28h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:15 am -
2 stops35h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:20 pm -
2 stops30h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$324
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $536 (Copa Airlines) |
One-way from | $274 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $805 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 12/1
6:30 pm-11:12 pm
3 stops48h 42m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$305
Quickest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sat 1/23
11:23 pm-3:16 pm
2 stops11h 53m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$340
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Fri 11/27
11:52 am-10:05 am
1 stop18h 13m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$344
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Thu 12/3
9:00 pm-4:20 pm
1 stop15h 20m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$364
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Thu 2/11
12:54 pm-5:49 am
3 stops36h 55m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$425
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sat 10/31
12:20 pm-9:19 pm
2 stops29h 59m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$426
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sun 2/21
7:36 pm-2:04 am
1 stop26h 28m
Santo Domingo Las Americas
Wed 3/3
8:48 am-11:05 pm
1 stop18h 17m
$554
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 3/23
7:55 pm-10:22 pm
1 stop23h 27m
Santo Domingo Las Americas
Sat 3/27
8:40 am-6:28 pm
1 stop12h 48m
$581
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sat 12/5
10:34 am-9:19 pm
3 stops30h 45m
Santo Domingo Las Americas
Sat 12/12
3:35 pm-7:31 pm
3 stops31h 56m
$699
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sat 12/5
9:35 pm-10:05 am
1 stop8h 30m
Santo Domingo Las Americas
Sat 12/12
6:00 am-7:20 pm
1 stop17h 20m
$742
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
Prices
More
How far ahead should I book a flight from San Francisco to Santo Domingo?
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $550). Flying from San Francisco to Santo Domingo in July is currently the most expensive (average of $898). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santo Domingo?
Airfare is below average for this route at the moment.
San Francisco to Santo Domingo flights typically cost between $580 and $849 in January.The cheapest round-trip price found within the last 5 days was $536 on Copa Airlines (Jan 19-Jan 26).
What’s the top layover airport for flights from San Francisco to Santo Domingo?
Share of 1-stop round-trip flights from San Francisco to Santo Domingo chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 60% of 1-stop itineraries from San Francisco to Santo Domingo on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Santo Domingo?
Average round-trip fare for 1-stop flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $524.
What’s the fastest layover option from San Francisco to Santo Domingo?
Shortest average travel time for 1-stop one-way flights from San Francisco to Santo Domingo, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via New York (JFK) have the shortest average one-way travel time for 1-stop routes: 11h 21m.
Which airport typically offers the quickest layover for flights from San Francisco to Santo Domingo?
Average layover duration for 1-stop one-way flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 2h 28m.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 22, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$420 | Average$551 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$433 | Average$634 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$542 | Average$576 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$587 | Average$863 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$682 | Average$943 | FlexibilityNo cancel fee | On-time71% |