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Santo Domingo

$215+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights

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Cheapflights Tip: The best prices from San Francisco to Santo Domingo Las Americas are usually found in October or September, booked 27 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from San Francisco to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$438
(SmartFares)

One-way from

$215
(JetBlue)

Popular in

December

Cheapest in

October

Average price

$694
Provider with most accurate pricing for San Francisco-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Santo Domingo Las Americas flights.
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From San Francisco to Santo Domingo Las Americas
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One-way flight from San Francisco to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Francisco to Santo Domingo

Cheapest flights from San Francisco to Santo Domingo
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Gotogate deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/712:36 amSFO - SDQ
1 stop21h 50mCopa Airlines
Wed 12/2412:40 pmSDQ - SFO
1 stop14h 37mCopa Airlines
Deal found 11/11$456
This Expedia deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:00 amSFO - SDQ
2 stops21h 34mJetBlue
Wed 12/173:32 pmSDQ - SFO
1 stop12h 03mJetBlue
Deal found 11/10$506
This JetBlue deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:44 pmSFO - SDQ
1 stop12h 34mJetBlue
Tue 12/163:28 pmSDQ - SFO
1 stop12h 07mJetBlue
Deal found 11/12$508
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:38 pmSFO - SDQ
2 stops18h 07mMultiple Airlines
Mon 12/156:10 amSDQ - SFO
1 stop33h 14mMultiple Airlines
Deal found 11/12$517
This Expedia deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:16 pmSFO - SDQ
2 stops17h 44mJetBlue
Mon 12/153:32 pmSDQ - SFO
1 stop21h 46mJetBlue
Deal found 11/12$526
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:00 amSFO - SDQ
1 stop13h 45mMultiple Airlines
Tue 12/164:21 pmSDQ - SFO
2 stops25h 42mMultiple Airlines
Deal found 11/12$533
This JetBlue deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:44 pmSFO - SDQ
1 stop12h 34mJetBlue
Tue 12/163:28 pmSDQ - SFO
1 stop12h 07mJetBlue
Deal found 11/12$551
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:49 amSFO - SDQ
2 stops21h 02mMultiple Airlines
Fri 12/192:53 pmSDQ - SFO
1 stop12h 17mMultiple Airlines
Deal found 11/12$554
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/233:12 pmSFO - SDQ
2 stops50h 33mMultiple Airlines
Sun 12/144:39 pmSDQ - SFO
1 stop24h 49mMultiple Airlines
Deal found 11/11$556
This Copa Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:36 amSFO - SDQ
1 stop11h 39mCopa Airlines
Mon 12/88:55 amSDQ - SFO
1 stop18h 22mCopa Airlines
Deal found 11/11$582

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

San Francisco

Fly to

Santo Domingo

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 1/23

7:00 am-2:32 am

1 stop15h 32m

Santo Domingo Las Americas

Tue 2/10

6:00 am-7:15 pm

1 stop17h 15m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 1/22

7:00 am-1:23 am

1 stop14h 23m

Santo Domingo Las Americas

Mon 2/9

6:00 am-7:15 pm

1 stop17h 15m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 1/23

8:26 am-4:34 am

1 stop16h 08m

Santo Domingo Las Americas

Mon 2/9

6:00 am-7:15 pm

1 stop17h 15m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 12/8

9:44 pm-2:18 pm

1 stop12h 34m

Santo Domingo Las Americas

Mon 12/15

3:32 pm-11:35 pm

1 stop12h 03m

$508

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 1/22

7:00 am-2:32 am

1 stop15h 32m

$215

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 11/30

6:00 am-9:45 pm

3 stops59h 45m

$285

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 11/19

8:55 pm-12:25 pm

3 stops59h 30m

$316

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 11/22

6:00 pm-3:30 pm

3 stops41h 30m

$331

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 11/18

12:36 am-2:26 am

1 stop21h 50m

$419

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 11/30

7:00 am-2:57 am

1 stop15h 57m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 14 results
1
2

Compare providers for flights from San Francisco to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santo Domingo

How far ahead should I book a flight from San Francisco to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santo Domingo. Price data was last updated on November 7, 2025.

The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Francisco to Santo Domingo?

Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SDQ?

Find hourly flight availability from San Francisco to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s typically best to fly out from San Francisco to Santo Domingo in the afternoon. Doing so could potentially save you 17% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from San Francisco to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Santo Domingo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta, Copa Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,565 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
JetBlue
7.2
Good
2,907 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,476 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santo Domingo?

    There are many flights that can get you from San Francisco to Santo Domingo in 15h 32m. Fly via JetBlue to get the fastest option. Airlines will cover a distance of 3424 mi.

  • What are the cheapest airlines flying from San Francisco to Santo Domingo round-trip?

    Currently priced at $378, Aeromexico will fly you from San Francisco to Santo Domingo and back. In addition to Aeromexico, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetBlue and Avianca - these airlines can fly you to your destination from $453 and $487, respectively. Aeromexico is 42% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from San Francisco to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santo Domingo.

  • Can I find deals for business class flights from San Francisco to Santo Domingo?

    Yes. Cheapflights offers flight deals from San Francisco to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santo Domingo?

    Currently, July is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $281). Flying from San Francisco to Santo Domingo in May is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 6 airlines flying from San Francisco to Santo Domingo

Discover the top 6 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$378Average$735FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$453Average$647FlexibilityNo cancel feeOn-time62%
AviancaCheapest$487Average$584FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$497Average$598FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$619Average$746FlexibilityNo cancel feeOn-time71%
DeltaCheapest$637Average$939FlexibilityNo cancel feeOn-timeN/A

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