$248+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Santo Domingo
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One-way
Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:14 pm -
1 stop18h 40m
Wed 11/117:00 am -
1 stop16h 16m
Deal found 8/6![American Airlines logo]()
$540
This Cheapflightsfares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:59 am -
1 stop10h 00m
Wed 9/910:10 am -
1 stop16h 07m
Deal found 8/6![JetBlue logo]()
$543
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:58 pm -
1 stop10h 56m
Mon 11/96:00 am -
2 stops16h 04m
Deal found 8/5![American Airlines logo]()
$545
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
1 stop15h 56m
Wed 9/233:59 pm -
1 stop10h 18m
Deal found 8/9![JetBlue logo]()
$549
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:36 pm -
1 stop16h 36m
Sun 11/158:55 am -
1 stop12h 30m
Deal found 8/10![Copa Airlines logo]()
$551
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:15 pm -
2 stops18h 35m
Tue 9/156:50 pm -
2 stops21h 00m
Deal found 8/10![Avianca logo]()
$552
This JetBlue deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:44 pm -
1 stop14h 41m
Fri 9/253:59 pm -
1 stop10h 18m
Deal found 8/6![JetBlue logo]()
$557
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:57 pm -
2 stops14h 36m
Sun 11/14:59 pm -
1 stop11h 13m
Deal found 8/7![American Airlines logo]()
$558
This Cheapflightsfares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
1 stop12h 51m
Fri 12/112:50 am -
1 stop13h 01m
Deal found 8/9![JetBlue logo]()
$561
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:03 pm -
1 stop18h 57m
Wed 2/177:00 am -
1 stop20h 43m
Deal found 8/7![American Airlines logo]()
$564
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:10 pm -
1 stop11h 09m
Tue 10/131:32 pm -
1 stop12h 45m
Deal found 8/5![JetBlue logo]()
$543
This Copa Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:36 pm -
1 stop23h 22m
Tue 11/1012:10 pm -
1 stop15h 02m
Deal found 8/9![Copa Airlines logo]()
$549
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:20 pm -
2 stops18h 05m
Tue 11/1712:20 pm -
2 stops27h 40m
Deal found 8/6![Avianca logo]()
$581
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:07 pm -
2 stops14h 15m
Tue 10/132:33 pm -
1 stop12h 26m
Deal found 8/5![American Airlines logo]()
$583
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:10 pm -
1 stop12h 39m
Fri 9/252:29 pm -
1 stop11h 48m
Deal found 8/5![JetBlue logo]()
$548
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:36 pm -
1 stop16h 36m
Sun 11/158:55 am -
1 stop12h 30m
Deal found 8/10![Copa Airlines logo]()
$551
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:30 am -
1 stop10h 29m
Tue 10/271:28 pm -
1 stop13h 02m
Deal found 8/5![JetBlue logo]()
$548
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:36 pm -
1 stop26h 32m
Mon 12/77:03 pm -
1 stop26h 22m
Deal found 8/6![Copa Airlines logo]()
$570
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1712:40 am -
1 stop21h 24m
Mon 2/18:54 am -
1 stop12h 31m
Deal found 8/6![Copa Airlines logo]()
$570
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated August 10, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:15 pm -
2 stops42h 35m
Fri 8/216:50 pm -
2 stops32h 05m
Deal found 8/6![Avianca logo]()
$597
This oojo deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:45 am -
3 stops25h 40m
Tue 8/256:50 pm -
3 stops38h 35m
Deal found 8/9![Avianca logo]()
$599
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:45 am -
3 stops49h 05m
Sat 8/226:50 pm -
3 stops38h 35m
Deal found 8/7![Avianca logo]()
$604
This Cheapflightsfares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:59 am -
1 stop10h 00m
Wed 9/910:10 am -
1 stop16h 07m
Deal found 8/6![JetBlue logo]()
$543
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:55 pm -
2 stops15h 00m
Tue 9/86:50 pm -
2 stops21h 00m
Deal found 8/9![Avianca logo]()
$553
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
1 stop15h 56m
Wed 9/233:59 pm -
1 stop10h 18m
Deal found 8/9![JetBlue logo]()
$549
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:15 pm -
2 stops18h 35m
Tue 9/156:50 pm -
2 stops21h 00m
Deal found 8/10![Avianca logo]()
$552
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:15 pm -
2 stops24h 40m
Mon 9/146:50 pm -
2 stops21h 00m
Deal found 8/10![Avianca logo]()
$581
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:10 pm -
1 stop12h 39m
Mon 9/212:29 pm -
1 stop11h 48m
Deal found 8/5![JetBlue logo]()
$619
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:10 pm -
1 stop12h 39m
Fri 9/252:29 pm -
1 stop11h 48m
Deal found 8/5![JetBlue logo]()
$548
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:17 pm -
2 stops23h 28m
Deal found 8/5![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:48 pm -
2 stops14h 41m
Deal found 8/7![Multiple Airlines logo]()
$249
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:30 am -
1 stop10h 29m
Deal found 8/7![JetBlue logo]()
$255
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:44 pm -
1 stop15h 11m
Deal found 8/7![JetBlue logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am -
3 stops55h 29m
Deal found 8/8![Multiple Airlines logo]()
$345
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm -
2 stops18h 35m
Deal found 8/7![Avianca logo]()
$351
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:15 pm -
2 stops18h 35m
Deal found 8/5![Avianca logo]()
$352
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:55 pm -
1 stop27h 52m
Deal found 8/6![Aeromexico logo]()
$357
This oojo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:15 pm -
2 stops24h 40m
Deal found 8/7![Avianca logo]()
$364
This oojo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3011:10 pm -
2 stops13h 40m
Deal found 8/8![Avianca logo]()
$365
This oojo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:55 pm -
1 stop27h 51m
Deal found 8/8![Aeromexico logo]()
$367
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $540 (American Airlines) |
One-way from | $248 (Kiwi.com) |
Popular in | July |
Cheapest in | October |
Average price | $668 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 10/6
11:10 pm-1:19 pm
1 stop11h 09m
Santo Domingo Las Americas
Tue 10/13
1:32 pm-11:17 pm
1 stop12h 45m
$543
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 9/22
11:10 pm-2:49 pm
1 stop12h 39m
Santo Domingo Las Americas
Fri 9/25
2:29 pm-11:17 pm
1 stop11h 48m
$548
Quickest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 10/20
10:30 am-11:59 pm
1 stop10h 29m
Santo Domingo Las Americas
Tue 10/27
1:28 pm-11:30 pm
1 stop13h 02m
$548
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 11/4
7:36 pm-10:58 pm
1 stop23h 22m
Santo Domingo Las Americas
Tue 11/10
12:10 pm-11:12 pm
1 stop15h 02m
$549
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 11/11
7:36 pm-4:12 pm
1 stop16h 36m
Santo Domingo Las Americas
Sun 11/15
8:55 am-5:25 pm
1 stop12h 30m
$551
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sun 11/29
7:36 pm-2:08 am
1 stop26h 32m
Santo Domingo Las Americas
Mon 12/7
7:03 pm-5:25 pm
1 stop26h 22m
$570
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sun 1/17
12:40 am-2:04 am
1 stop21h 24m
Santo Domingo Las Americas
Mon 2/1
8:54 am-5:25 pm
1 stop12h 31m
$570
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 11/11
1:20 pm-11:25 am
2 stops18h 05m
Santo Domingo Las Americas
Tue 11/17
12:20 pm-12:00 pm
2 stops27h 40m
$581
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Tue 10/6
4:07 pm-9:22 am
2 stops14h 15m
Santo Domingo Las Americas
Tue 10/13
2:33 pm-11:59 pm
1 stop12h 26m
$583
Cheapest one-way
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Fri 10/23
7:17 pm-9:45 pm
2 stops23h 28m
$248
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
Prices
More
How far ahead should I book a flight from San Francisco to Santo Domingo?
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 23 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $532). Flying from San Francisco to Santo Domingo in July is currently the most expensive (average of $898). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santo Domingo?
Airfare is typical for this route at the moment.
San Francisco to Santo Domingo flights typically cost between $535 and $774 in November.The cheapest round-trip price found within the last 5 days was $540 on American Airlines (Nov 6-Nov 11).
What’s the top layover airport for flights from San Francisco to Santo Domingo?
Share of 1-stop round-trip flights from San Francisco to Santo Domingo chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 60% of 1-stop itineraries from San Francisco to Santo Domingo on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Santo Domingo?
Average round-trip fare for 1-stop flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $524.
What’s the fastest layover option from San Francisco to Santo Domingo?
Shortest average travel time for 1-stop one-way flights from San Francisco to Santo Domingo, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via New York (JFK) have the shortest average one-way travel time for 1-stop routes: 11h 21m.
Which airport typically offers the quickest layover for flights from San Francisco to Santo Domingo?
Average layover duration for 1-stop one-way flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 2h 28m.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$313 | Average$575 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$420 | Average$539 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$432 | Average$614 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$828 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$679 | Average$893 | FlexibilityNo cancel fee | On-time71% |