$225+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
May 25 — Jun 11
Round-trip
1 adult, Economy
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Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:12 am
SFO
- SDQ
1 stop12h 03m
Copa Airlines
Tue 9/1512:12 pm
SDQ
- SFO
1 stop14h 28m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$500
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:52 pm
SFO
- SDQ
2 stops19h 13m
Frontier
Sun 6/1411:55 am
SDQ
- SFO
2 stops23h 56m
Frontier
Deal found 4/21![Frontier logo]()
$509
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
SFO
- SDQ
1 stop16h 11m
JetBlue
Tue 9/152:30 pm
SDQ
- SFO
1 stop11h 38m
JetBlue
Deal found 4/21![JetBlue logo]()
$519
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:21 pm
SFO
- SDQ
1 stop11h 40m
Copa Airlines
Sun 11/158:50 am
SDQ
- SFO
1 stop18h 30m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$523
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:41 pm
SFO
- SDQ
2 stops13h 12m
Frontier
Thu 5/2810:58 am
SDQ
- SFO
2 stops24h 03m
Frontier
Deal found 4/20![Frontier logo]()
$530
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:16 pm
SFO
- SDQ
1 stop13h 57m
Copa Airlines
Thu 8/208:48 am
SDQ
- SFO
1 stop17h 52m
Copa Airlines
Deal found 4/23![Copa Airlines logo]()
$540
This Avianca deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Fri 5/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/24![Avianca logo]()
$541
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 5/136:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/22![Avianca logo]()
$542
This Travelocity deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1710:45 pm
SFO
- SDQ
1 stop10h 43m
JetBlue
Fri 5/221:26 pm
SDQ
- SFO
1 stop14h 40m
JetBlue
Deal found 4/21![JetBlue logo]()
$565
This JetBlue deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:33 pm
SFO
- SDQ
1 stop11h 55m
JetBlue
Fri 5/229:20 am
SDQ
- SFO
1 stop18h 13m
JetBlue
Deal found 4/24![JetBlue logo]()
$566
This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Sun 5/246:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/23![Avianca logo]()
$572
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Thu 5/1412:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Deal found 4/23![Avianca logo]()
$577
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:12 am
SFO
- SDQ
1 stop12h 03m
Copa Airlines
Tue 9/1512:12 pm
SDQ
- SFO
1 stop14h 28m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$500
This Avianca deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Fri 5/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/24![Avianca logo]()
$541
This JetBlue deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:44 pm
SFO
- SDQ
1 stop15h 11m
JetBlue
Fri 5/151:40 pm
SDQ
- SFO
1 stop13h 11m
JetBlue
Deal found 4/20![JetBlue logo]()
$608
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:21 pm
SFO
- SDQ
1 stop16h 54m
Copa Airlines
Wed 9/302:16 pm
SDQ
- SFO
1 stop12h 24m
Copa Airlines
Deal found 4/22![Copa Airlines logo]()
$523
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:16 pm
SFO
- SDQ
1 stop13h 57m
Copa Airlines
Thu 8/208:48 am
SDQ
- SFO
1 stop17h 52m
Copa Airlines
Deal found 4/23![Copa Airlines logo]()
$540
This SmartFares deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 6/312:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Deal found 4/20![Avianca logo]()
$601
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:37 am
SFO
- SDQ
1 stop17h 32m
JetBlue
Sun 5/316:47 pm
SDQ
- SFO
1 stop18h 25m
JetBlue
Deal found 4/24![JetBlue logo]()
$681
This FlightHub deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/212:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Fri 7/3112:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 4/24![Avianca logo]()
$630
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:12 am
SFO
- SDQ
1 stop12h 03m
Copa Airlines
Tue 8/116:07 am
SDQ
- SFO
1 stop20h 33m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$600
This Copa Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:12 am
SFO
- SDQ
1 stop12h 03m
Copa Airlines
Sat 9/1212:42 pm
SDQ
- SFO
1 stop13h 58m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$702
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated April 25, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Thu 5/1412:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Deal found 4/23![Avianca logo]()
$577
This Avianca deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Fri 5/226:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/24![Avianca logo]()
$541
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Wed 5/136:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/22![Avianca logo]()
$542
This JetBlue deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:33 pm
SFO
- SDQ
1 stop11h 55m
JetBlue
Fri 5/229:20 am
SDQ
- SFO
1 stop18h 13m
JetBlue
Deal found 4/24![JetBlue logo]()
$566
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:33 pm
SFO
- SDQ
1 stop11h 55m
JetBlue
Wed 5/135:01 am
SDQ
- SFO
1 stop21h 58m
JetBlue
Deal found 4/22![JetBlue logo]()
$604
This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Sun 5/246:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/23![Avianca logo]()
$572
This Travelocity deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1710:45 pm
SFO
- SDQ
1 stop10h 43m
JetBlue
Fri 5/221:26 pm
SDQ
- SFO
1 stop14h 40m
JetBlue
Deal found 4/21![JetBlue logo]()
$565
This FlightHub deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:30 am
SFO
- SDQ
2 stops30h 20m
Multiple Airlines
Thu 5/284:14 pm
SDQ
- SFO
1 stop12h 22m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$582
This Justfly.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:15 pm
SFO
- SDQ
2 stops48h 40m
Avianca
Mon 5/256:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 4/20![Avianca logo]()
$602
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:41 pm
SFO
- SDQ
2 stops13h 12m
Frontier
Thu 5/2810:58 am
SDQ
- SFO
2 stops24h 03m
Frontier
Deal found 4/20![Frontier logo]()
$530
This Travelocity deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:00 pm
SFO
- SDQ
1 stop25h 44m
JetBlue
Thu 5/284:14 pm
SDQ
- SFO
1 stop12h 22m
JetBlue
Deal found 4/20![JetBlue logo]()
$590
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:45 pm
SFO
- SDQ
3 stops42h 44m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:56 pm
SFO
- SDQ
3 stops39h 33m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:26 pm
SFO
- SDQ
2 stops20h 03m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:33 pm
SFO
- SDQ
2 stops21h 56m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$258
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Deal found 4/21![Avianca logo]()
$261
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:55 pm
SFO
- SDQ
2 stops15h 00m
Avianca
Deal found 4/20![Avianca logo]()
$262
This Avianca deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Deal found 4/19![Avianca logo]()
$270
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $500 (Copa Airlines) |
One-way from | $225 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $750 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 8/31
1:12 am-4:15 pm
1 stop12h 03m
Santo Domingo Las Americas
Tue 9/15
12:12 pm-11:40 pm
1 stop14h 28m
$500
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 9/27
8:21 pm-4:15 pm
1 stop16h 54m
Santo Domingo Las Americas
Wed 9/30
2:16 pm-11:40 pm
1 stop12h 24m
$523
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 7/29
8:16 pm-1:13 pm
1 stop13h 57m
Santo Domingo Las Americas
Thu 8/20
8:48 am-11:40 pm
1 stop17h 52m
$540
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sat 5/9
2:15 pm-11:50 am
2 stops18h 35m
Santo Domingo Las Americas
Fri 5/22
6:50 pm-12:50 pm
2 stops21h 00m
$541
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 8/5
1:12 am-4:15 pm
1 stop12h 03m
Santo Domingo Las Americas
Tue 8/11
6:07 am-11:40 pm
1 stop20h 33m
$600
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 6/1
2:15 pm-11:50 am
2 stops18h 35m
Santo Domingo Las Americas
Wed 6/3
12:45 pm-12:50 pm
2 stops27h 05m
$601
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 5/11
8:44 pm-2:55 pm
1 stop15h 11m
Santo Domingo Las Americas
Fri 5/15
1:40 pm-11:51 pm
1 stop13h 11m
$608
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 7/21
2:30 am-5:55 pm
2 stops36h 25m
Santo Domingo Las Americas
Fri 7/31
12:45 pm-11:55 pm
2 stops38h 10m
$630
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 5/27
11:37 am-8:09 am
1 stop17h 32m
Santo Domingo Las Americas
Sun 5/31
6:47 pm-10:12 am
1 stop18h 25m
$681
Quickest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Fri 9/4
1:12 am-4:15 pm
1 stop12h 03m
Santo Domingo Las Americas
Sat 9/12
12:42 pm-11:40 pm
1 stop13h 58m
$702
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
How far ahead should I book a flight from San Francisco to Santo Domingo?
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 5 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $536). Flying from San Francisco to Santo Domingo in March is currently the most expensive (average of $868). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santo Domingo?
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated April 25, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Alternative routes for San Francisco to Santo Domingo
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Complete your trip
Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Santo Domingo by cabin class
Find flights from San Francisco to Santo Domingo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Santo Domingo flights
Browse other San Francisco and Santo Domingo flight options. Last updated on April 25, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$313 | Average$584 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$420 | Average$539 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$433 | Average$604 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$818 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$617 | Average$749 | FlexibilityNo cancel fee | On-time71% |