$257+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Santo Domingo
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Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:10 pm -
1 stop12h 30m
Fri 10/301:32 pm -
1 stop12h 02m
Deal found 9/8![JetBlue logo]()
$536
This Cheapflightsfares deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:30 am -
1 stop15h 35m
Wed 11/112:32 pm -
1 stop11h 58m
Deal found 9/4![JetBlue logo]()
$545
This JetBlue deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:30 am -
1 stop9h 21m
Fri 11/62:32 pm -
1 stop11h 58m
Deal found 9/6![JetBlue logo]()
$548
This JetBlue deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop16h 57m
Thu 12/32:42 pm -
1 stop11h 34m
Deal found 9/6![JetBlue logo]()
$557
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:04 pm -
1 stop18h 05m
Thu 11/126:00 am -
2 stops13h 09m
Deal found 9/4![American Airlines logo]()
$558
This Avianca deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:15 pm -
2 stops18h 35m
Wed 11/46:45 pm -
2 stops21h 10m
Deal found 9/3![Avianca logo]()
$562
This JetBlue deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop16h 57m
Wed 12/26:01 am -
1 stop13h 30m
Deal found 9/6![JetBlue logo]()
$566
This Avianca deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:15 pm -
2 stops18h 35m
Sat 9/266:50 pm -
2 stops21h 00m
Deal found 9/3![Avianca logo]()
$570
This Cheapflightsfares deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:50 am -
1 stop12h 44m
Sat 12/126:30 am -
1 stop18h 10m
Deal found 9/4![JetBlue logo]()
$572
This JetBlue deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop16h 57m
Sun 12/611:11 am -
1 stop15h 11m
Deal found 9/6![JetBlue logo]()
$575
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:55 pm -
2 stops32h 55m
Sat 10/1712:45 pm -
2 stops27h 05m
Deal found 9/4![Avianca logo]()
$597
This Justfly.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:55 pm -
2 stops39h 00m
Tue 10/1312:45 pm -
2 stops36h 50m
Deal found 9/3![Avianca logo]()
$605
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 pm -
1 stop12h 33m
Tue 11/32:32 pm -
1 stop12h 02m
Deal found 9/8![JetBlue logo]()
$548
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:36 pm -
1 stop11h 25m
Mon 2/17:02 pm -
1 stop26h 23m
Deal found 9/6![Copa Airlines logo]()
$570
This Avianca deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:15 pm -
2 stops18h 35m
Mon 11/26:45 pm -
2 stops21h 10m
Deal found 9/3![Avianca logo]()
$625
This Justfly.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:55 pm -
1 stop27h 47m
Thu 10/81:32 pm -
1 stop13h 35m
Deal found 9/3![Multiple Airlines logo]()
$684
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:54 pm -
1 stop17h 40m
Thu 10/87:00 am -
2 stops12h 10m
Deal found 9/3![American Airlines logo]()
$735
This JetBlue deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:30 am -
1 stop9h 21m
Fri 11/62:32 pm -
1 stop11h 58m
Deal found 9/5![JetBlue logo]()
$548
This JetBlue deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:50 am -
1 stop10h 09m
Tue 12/82:42 pm -
1 stop11h 34m
Deal found 9/6![JetBlue logo]()
$548
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:21 pm -
1 stop16h 53m
Fri 11/612:45 pm -
1 stop14h 27m
Deal found 9/4![Copa Airlines logo]()
$694
This JetBlue deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:40 am -
1 stop12h 24m
Thu 10/291:32 pm -
1 stop12h 02m
Deal found 9/7![JetBlue logo]()
$624
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:36 pm -
1 stop12h 09m
Mon 12/78:55 am -
1 stop18h 22m
Deal found 9/8![Copa Airlines logo]()
$734
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated September 8, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:15 pm -
2 stops18h 35m
Sat 9/266:50 pm -
2 stops21h 00m
Deal found 9/3![Avianca logo]()
$570
This Justfly.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:55 pm -
2 stops39h 00m
Tue 10/1312:45 pm -
2 stops36h 50m
Deal found 9/3![Avianca logo]()
$605
This Cheapflightsfares deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:10 pm -
1 stop12h 30m
Wed 10/143:50 pm -
1 stop11h 17m
Deal found 9/7![JetBlue logo]()
$612
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:55 pm -
2 stops32h 55m
Sat 10/1712:45 pm -
2 stops27h 05m
Deal found 9/4![Avianca logo]()
$597
This Avianca deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:15 pm -
2 stops18h 35m
Wed 11/46:45 pm -
2 stops21h 10m
Deal found 9/3![Avianca logo]()
$562
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:13 pm -
2 stops47h 32m
Fri 11/66:10 am -
1 stop21h 49m
Deal found 9/4![Multiple Airlines logo]()
$617
This JetBlue deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:40 am -
1 stop12h 24m
Thu 10/291:32 pm -
1 stop12h 02m
Deal found 9/7![JetBlue logo]()
$624
This Cheapflightsfares deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:10 pm -
1 stop12h 30m
Fri 10/301:32 pm -
1 stop12h 02m
Deal found 9/8![JetBlue logo]()
$536
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:55 pm -
2 stops14h 55m
Mon 11/26:45 pm -
2 stops21h 10m
Deal found 9/4![Avianca logo]()
$625
This Cheapflightsfares deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 pm -
1 stop9h 37m
Mon 11/26:39 pm -
1 stop19h 01m
Deal found 9/3![JetBlue logo]()
$545
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 pm -
1 stop12h 33m
Tue 11/32:32 pm -
1 stop12h 02m
Deal found 9/8![JetBlue logo]()
$548
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:25 pm -
1 stop9h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![JetBlue logo]()
$257
This Cheapflightsfares deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:18 pm -
1 stop16h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![JetBlue logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:57 pm -
2 stops13h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/106:35 am -
2 stops11h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:19 pm -
3 stops41h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:14 pm -
3 stops22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$320
This Cheapflightsfares deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:40 am -
1 stop12h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![JetBlue logo]()
$324
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/108:00 am -
1 stop12h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![JetBlue logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/106:18 am -
3 stops19h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:05 pm -
2 stops18h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$347
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $536 (Cheapflightsfares) |
One-way from | $257 (Expedia) |
Popular in | July |
Cheapest in | January |
Average price | $676 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Mon 9/28
11:10 pm-2:49 pm
1 stop12h 39m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$257
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 11/18
10:44 am-4:05 am
1 stop13h 21m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$266
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Thu 10/22
2:18 pm-9:54 am
1 stop16h 36m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$266
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Sat 11/7
12:20 pm-9:19 pm
2 stops28h 59m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$273
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Fri 10/9
10:19 pm-7:18 pm
3 stops41h 59m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$302
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Thu 10/22
7:57 pm-12:35 pm
2 stops13h 38m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$339
Quickest round-trip
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Thu 11/19
11:07 pm-1:50 pm
1 stop10h 43m
Santo Domingo Las Americas
Wed 12/31
12:00 am-8:30 pm
Nonstop0h 00m
$339
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 10/28
11:45 pm-3:18 pm
1 stop12h 33m
Santo Domingo Las Americas
Tue 11/3
2:32 pm-10:34 pm
1 stop12h 02m
$548
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Mon 11/2
11:30 am-12:51 am
1 stop9h 21m
Santo Domingo Las Americas
Fri 11/6
2:32 pm-10:30 pm
1 stop11h 58m
$548
San FranciscoSanto Domingo
SFO San Francisco - SDQ Santo Domingo Las Americas
SFOSDQ
San Francisco
Wed 11/25
10:50 am-12:59 am
1 stop10h 09m
Santo Domingo Las Americas
Tue 12/8
2:42 pm-10:16 pm
1 stop11h 34m
$548
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
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How far ahead should I book a flight from San Francisco to Santo Domingo?
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 23 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $550). Flying from San Francisco to Santo Domingo in July is currently the most expensive (average of $898). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santo Domingo?
Airfare is below average for this route at the moment.
San Francisco to Santo Domingo flights typically cost between $549 and $718 in October.The cheapest round-trip price found within the last 5 days was $536 on JetBlue (Oct 6-Oct 8).
What’s the top layover airport for flights from San Francisco to Santo Domingo?
Share of 1-stop round-trip flights from San Francisco to Santo Domingo chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 60% of 1-stop itineraries from San Francisco to Santo Domingo on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Santo Domingo?
Average round-trip fare for 1-stop flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $524.
What’s the fastest layover option from San Francisco to Santo Domingo?
Shortest average travel time for 1-stop one-way flights from San Francisco to Santo Domingo, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via New York (JFK) have the shortest average one-way travel time for 1-stop routes: 11h 21m.
Which airport typically offers the quickest layover for flights from San Francisco to Santo Domingo?
Average layover duration for 1-stop one-way flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 2h 28m.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 8, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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San Francisco and Santo Domingo flights
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Top 5 airlines flying from San Francisco to Santo Domingo
Discover the top 5 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$313 | Average$575 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$420 | Average$551 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$432 | Average$627 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$828 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$634 | Average$895 | FlexibilityNo cancel fee | On-time71% |