$281+ Cheap flights from San Francisco (SFO) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SDQ
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Santo Domingo
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Cheapest flights from San Francisco to Santo DomingoExplore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from San Francisco to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:36 pm
SFO
- SDQ
1 stop23h 22m
Copa Airlines
Sun 11/155:55 am
SDQ
- SFO
1 stop15h 30m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$533
This Avianca deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Sun 7/196:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 6/9![Avianca logo]()
$542
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:33 am
SFO
- SDQ
1 stop21h 35m
Copa Airlines
Wed 11/257:06 pm
SDQ
- SFO
1 stop26h 19m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$547
This oojo deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:15 pm
SFO
- SDQ
2 stops24h 40m
Avianca
Wed 7/1512:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/8![Avianca logo]()
$551
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Tue 7/1412:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Deal found 6/5![Avianca logo]()
$559
This Copa Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:36 pm
SFO
- SDQ
1 stop13h 34m
Copa Airlines
Wed 11/2512:45 pm
SDQ
- SFO
1 stop14h 27m
Copa Airlines
Deal found 6/8![Copa Airlines logo]()
$560
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Sun 8/912:45 pm
SDQ
- SFO
2 stops36h 50m
Avianca
Deal found 6/5![Avianca logo]()
$561
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:45 am
SFO
- SDQ
3 stops31h 10m
Avianca
Wed 8/126:50 pm
SDQ
- SFO
2 stops30h 45m
Avianca
Deal found 6/5![Avianca logo]()
$568
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Fri 8/712:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/5![Avianca logo]()
$569
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:10 pm
SFO
- SDQ
2 stops13h 40m
Avianca
Mon 11/95:45 pm
SDQ
- SFO
2 stops32h 55m
Avianca
Deal found 6/5![Avianca logo]()
$577
Best flights from San Francisco to Santo DomingoDiscover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from San Francisco to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:33 am
SFO
- SDQ
1 stop21h 35m
Copa Airlines
Wed 11/257:06 pm
SDQ
- SFO
1 stop26h 19m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$547
This oojo deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:15 pm
SFO
- SDQ
2 stops24h 40m
Avianca
Wed 7/1512:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/8![Avianca logo]()
$551
This JetBlue deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:57 am
SFO
- SDQ
1 stop10h 02m
JetBlue
Wed 9/21:34 pm
SDQ
- SFO
1 stop13h 16m
JetBlue
Deal found 6/8![JetBlue logo]()
$662
This FlightHub deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:55 pm
SFO
- SDQ
2 stops32h 55m
Avianca
Fri 8/712:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/4![Avianca logo]()
$577
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:36 pm
SFO
- SDQ
1 stop23h 22m
Copa Airlines
Sun 11/152:24 pm
SDQ
- SFO
1 stop12h 48m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$580
This Avianca deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:45 am
SFO
- SDQ
3 stops31h 10m
Avianca
Wed 9/26:50 pm
SDQ
- SFO
2 stops32h 05m
Avianca
Deal found 6/7![Avianca logo]()
$614
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:33 am
SFO
- SDQ
1 stop11h 39m
Copa Airlines
Wed 11/118:55 am
SDQ
- SFO
1 stop18h 17m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$628
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:33 am
SFO
- SDQ
1 stop18h 25m
Copa Airlines
Sun 11/152:24 pm
SDQ
- SFO
1 stop12h 48m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$651
Last-minute flights from San Francisco to Santo DomingoDiscover last-minute flight deals from San Francisco to Santo Domingo. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santo Domingo. Data last updated June 9, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Tue 7/1412:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Deal found 6/5![Avianca logo]()
$559
This Justfly.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:15 pm
SFO
- SDQ
2 stops42h 35m
Avianca
Sat 7/1112:45 pm
SDQ
- SFO
3 stops44h 40m
Avianca
Deal found 6/5![Avianca logo]()
$602
This Avianca deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Sun 7/196:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Deal found 6/9![Avianca logo]()
$542
This oojo deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:15 pm
SFO
- SDQ
2 stops24h 40m
Avianca
Wed 7/1512:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/8![Avianca logo]()
$551
This oojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Fri 7/1712:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/9![Avianca logo]()
$569
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:45 am
SFO
- SDQ
3 stops31h 10m
Avianca
Fri 7/1712:45 pm
SDQ
- SFO
2 stops38h 10m
Avianca
Deal found 6/9![Avianca logo]()
$595
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:15 pm
SFO
- SDQ
2 stops24h 40m
Avianca
Tue 7/216:50 pm
SDQ
- SFO
2 stops45h 00m
Avianca
Deal found 6/9![Avianca logo]()
$612
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:30 am
SFO
- SDQ
2 stops36h 25m
Avianca
Sun 8/912:45 pm
SDQ
- SFO
2 stops36h 50m
Avianca
Deal found 6/5![Avianca logo]()
$561
One-way flights from San Francisco to Santo DomingoSearch for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from San Francisco to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Faresmojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:40 pm
SFO
- SDQ
1 stop22h 19m
JetBlue
Deal found 6/9![JetBlue logo]()
$281
This Cheapflightsfares deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:40 pm
SFO
- SDQ
1 stop10h 44m
JetBlue
Deal found 6/5![JetBlue logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:43 pm
SFO
- SDQ
2 stops27h 02m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$316
This SmartFares deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:40 pm
SFO
- SDQ
1 stop13h 43m
JetBlue
Deal found 6/8![JetBlue logo]()
$349
This Avianca deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/212:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Deal found 6/9![Avianca logo]()
$351
This Avianca deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:55 pm
SFO
- SDQ
2 stops15h 00m
Avianca
Deal found 6/8![Avianca logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:45 am
SFO
- SDQ
3 stops31h 10m
Avianca
Deal found 6/8![Avianca logo]()
$372
This oojo deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/132:30 am
SFO
- SDQ
2 stops30h 20m
Avianca
Deal found 6/5![Avianca logo]()
$390
This Cheapflightsfares deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:57 am
SFO
- SDQ
1 stop10h 02m
JetBlue
Deal found 6/6![JetBlue logo]()
$405
Find flight deals from San Francisco to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $533 (Copa Airlines) |
One-way from | $281 (Faresmojo) |
Popular in | March |
Cheapest in | October |
Average price | $698 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 11/10
12:33 am-2:08 am
1 stop21h 35m
Santo Domingo Las Americas
Wed 11/25
7:06 pm-5:25 pm
1 stop26h 19m
$547
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 7/8
2:15 pm-5:55 pm
2 stops24h 40m
Santo Domingo Las Americas
Wed 7/15
12:45 pm-11:55 pm
2 stops38h 10m
$551
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 8/3
11:55 pm-11:50 am
2 stops32h 55m
Santo Domingo Las Americas
Fri 8/7
12:45 pm-11:55 pm
2 stops38h 10m
$577
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Sun 11/1
7:36 pm-10:58 pm
1 stop23h 22m
Santo Domingo Las Americas
Sun 11/15
2:24 pm-11:12 pm
1 stop12h 48m
$580
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 8/31
7:45 am-5:55 pm
3 stops31h 10m
Santo Domingo Las Americas
Wed 9/2
6:50 pm-11:55 pm
2 stops32h 05m
$614
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Thu 11/5
12:33 am-4:12 pm
1 stop11h 39m
Santo Domingo Las Americas
Wed 11/11
8:55 am-11:12 pm
1 stop18h 17m
$628
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Wed 11/11
12:33 am-10:58 pm
1 stop18h 25m
Santo Domingo Las Americas
Sun 11/15
2:24 pm-11:12 pm
1 stop12h 48m
$651
Quickest round-trip
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 8/31
10:57 am-11:59 pm
1 stop10h 02m
Santo Domingo Las Americas
Wed 9/2
1:34 pm-11:50 pm
1 stop13h 16m
$662
Cheapest one-way
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Tue 7/21
10:40 pm-11:59 pm
1 stop22h 19m
$281
San FranciscoSanto Domingo
SFO - SDQ
SFOSDQ
San Francisco
Mon 7/20
3:43 pm-9:45 pm
2 stops27h 02m
$316
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santo Domingo in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from San Francisco with our price prediction graph.
SFO-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santo Domingo
Prices
More
How far ahead should I book a flight from San Francisco to Santo Domingo?
The price you pay for your flight from San Francisco to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 23 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Francisco to Santo Domingo?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Santo Domingo (average of $532). Flying from San Francisco to Santo Domingo in March is currently the most expensive (average of $868). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santo Domingo?
What’s the top layover airport for flights from San Francisco to Santo Domingo?
Share of 1-stop round-trip flights from San Francisco to Santo Domingo chosen by Cheapflights users in the past 12 months, using the same layover each way.
New York (JFK) – chosen by Cheapflights users on 67% of 1-stop itineraries from San Francisco to Santo Domingo on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Santo Domingo?
Average round-trip fare for 1-stop flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $532.
What’s the fastest layover option from San Francisco to Santo Domingo?
Shortest average travel time for 1-stop one-way flights from San Francisco to Santo Domingo, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via New York (JFK) have the shortest average one-way travel time for 1-stop routes: 11h 21m.
Which airport typically offers the quickest layover for flights from San Francisco to Santo Domingo?
Average layover duration for 1-stop one-way flights from San Francisco to Santo Domingo, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 2h 22m.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated June 9, 2026.
Read through reviews of airlines operating flights from San Francisco to Santo Domingo, such as Delta,Copa Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.9
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Top 4 airlines flying from San Francisco to Santo Domingo
Discover the top 4 airlines that operate flights from San Francisco to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$420 | Average$539 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$432 | Average$597 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$828 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$679 | Average$893 | FlexibilityNo cancel fee | On-time71% |