$280+ Cheap flights from Santo Domingo (SDQ) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SFO
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to San Francisco
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Cheapest flights from Santo Domingo to San FranciscoExplore the most affordable flight options available from Santo Domingo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Santo Domingo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:19 am
SDQ
- SFO
2 stops41h 04m
Multiple Airlines
Tue 5/123:26 pm
SFO
- SDQ
3 stops64h 39m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$526
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/712:10 pm
SDQ
- SFO
2 stops22h 51m
Frontier
Sun 6/143:59 pm
SFO
- SDQ
2 stops16h 07m
Frontier
Deal found 4/23![Frontier logo]()
$600
This Frontier deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:58 am
SDQ
- SFO
2 stops24h 03m
Frontier
Mon 6/83:33 pm
SFO
- SDQ
2 stops16h 33m
Frontier
Deal found 4/25![Frontier logo]()
$604
This Copa Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:42 pm
SDQ
- SFO
1 stop13h 58m
Copa Airlines
Fri 10/21:12 am
SFO
- SDQ
1 stop18h 44m
Copa Airlines
Deal found 4/27![Copa Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:35 pm
SDQ
- SFO
2 stops23h 12m
Multiple Airlines
Sat 5/309:25 pm
SFO
- SDQ
1 stop29h 04m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$643
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:10 pm
SDQ
- SFO
1 stop19h 48m
Multiple Airlines
Mon 6/1510:58 pm
SFO
- SDQ
2 stops38h 31m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$647
This Orbitz deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:45 am
SDQ
- SFO
1 stop19h 46m
Multiple Airlines
Sat 9/262:30 am
SFO
- SDQ
2 stops30h 20m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$674
This eDestinos deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/712:10 pm
SDQ
- SFO
3 stops49h 24m
Multiple Airlines
Thu 6/112:30 am
SFO
- SDQ
2 stops36h 25m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$678
Best flights from Santo Domingo to San FranciscoDiscover carefully curated flight deals from Santo Domingo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Santo Domingo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:12 pm
SDQ
- SFO
1 stop14h 28m
Copa Airlines
Fri 10/21:12 am
SFO
- SDQ
1 stop18h 44m
Copa Airlines
Deal found 4/25![Copa Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:35 pm
SDQ
- SFO
2 stops23h 12m
Multiple Airlines
Sat 5/309:25 pm
SFO
- SDQ
1 stop29h 04m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$643
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:50 pm
SDQ
- SFO
2 stops30h 45m
Avianca
Sat 5/3011:55 pm
SFO
- SDQ
2 stops32h 55m
Avianca
Deal found 4/23![Avianca logo]()
$745
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:45 pm
SDQ
- SFO
1 stop14h 39m
Delta
Sun 9/2710:45 pm
SFO
- SDQ
1 stop10h 35m
Delta
Deal found 4/26![Delta logo]()
$783
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:01 am
SDQ
- SFO
1 stop21h 35m
JetBlue
Tue 7/1410:40 pm
SFO
- SDQ
1 stop13h 41m
JetBlue
Deal found 4/24![JetBlue logo]()
$794
This Travelocity deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:01 am
SDQ
- SFO
1 stop32h 52m
Multiple Airlines
Thu 6/112:30 am
SFO
- SDQ
2 stops30h 20m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$725
This Orbitz deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:01 am
SDQ
- SFO
1 stop21h 35m
Multiple Airlines
Tue 7/147:45 am
SFO
- SDQ
3 stops31h 10m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$747
Last-minute flights from Santo Domingo to San FranciscoDiscover last-minute flight deals from Santo Domingo to San Francisco. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to San Francisco. Data last updated April 28, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:50 pm
SDQ
- SFO
2 stops21h 00m
Avianca
Thu 5/72:15 pm
SFO
- SDQ
2 stops18h 35m
Avianca
Deal found 4/25![Avianca logo]()
$767
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:19 am
SDQ
- SFO
2 stops41h 04m
Multiple Airlines
Tue 5/123:26 pm
SFO
- SDQ
3 stops64h 39m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$526
This SmartFares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:01 am
SDQ
- SFO
1 stop21h 58m
JetBlue
Tue 5/128:00 am
SFO
- SDQ
1 stop25h 28m
JetBlue
Deal found 4/23![JetBlue logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:35 pm
SDQ
- SFO
2 stops23h 12m
Multiple Airlines
Sat 5/309:25 pm
SFO
- SDQ
1 stop29h 04m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$643
This Travelocity deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:10 am
SDQ
- SFO
1 stop13h 45m
Multiple Airlines
Sun 5/312:15 pm
SFO
- SDQ
2 stops24h 40m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$700
This SmartFares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:01 am
SDQ
- SFO
1 stop23h 05m
JetBlue
Sat 5/308:40 pm
SFO
- SDQ
1 stop8h 29m
JetBlue
Deal found 4/23![JetBlue logo]()
$716
This SmartFares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:10 am
SDQ
- SFO
1 stop13h 45m
JetBlue
Sun 5/318:40 pm
SFO
- SDQ
1 stop8h 29m
JetBlue
Deal found 4/24![JetBlue logo]()
$742
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:50 pm
SDQ
- SFO
2 stops30h 45m
Avianca
Sat 5/3011:55 pm
SFO
- SDQ
2 stops32h 55m
Avianca
Deal found 4/23![Avianca logo]()
$745
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:45 pm
SDQ
- SFO
2 stops27h 05m
Avianca
Sun 5/3111:55 pm
SFO
- SDQ
2 stops32h 55m
Avianca
Deal found 4/24![Avianca logo]()
$734
One-way flights from Santo Domingo to San FranciscoSearch for one-way flight options from Santo Domingo to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Santo Domingo to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:19 am
SDQ
- SFO
2 stops39h 45m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:35 pm
SDQ
- SFO
2 stops35h 48m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:41 pm
SDQ
- SFO
3 stops33h 53m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/313:35 pm
SDQ
- SFO
3 stops57h 20m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:19 am
SDQ
- SFO
2 stops40h 59m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:19 am
SDQ
- SFO
2 stops48h 42m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:19 am
SDQ
- SFO
2 stops28h 28m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:19 am
SDQ
- SFO
2 stops41h 04m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:19 am
SDQ
- SFO
3 stops38h 36m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:35 pm
SDQ
- SFO
2 stops21h 55m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$320
Find flight deals from Santo Domingo to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $526 (eDestinos) |
One-way from | $280 (Kiwi.com) |
Popular in | April |
Cheapest in | June |
Average price | $783 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Thu 9/24
12:12 pm-11:40 pm
1 stop14h 28m
San Francisco
Fri 10/2
1:12 am-10:56 pm
1 stop18h 44m
$627
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Sat 5/23
3:35 pm-11:47 am
2 stops23h 12m
San Francisco
Sat 5/30
9:25 pm-5:29 am
1 stop29h 04m
$643
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Sun 6/7
5:01 am-10:53 am
1 stop32h 52m
San Francisco
Thu 6/11
2:30 am-11:50 am
2 stops30h 20m
$725
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Sat 5/23
6:50 pm-10:35 pm
2 stops30h 45m
San Francisco
Sat 5/30
11:55 pm-11:50 am
2 stops32h 55m
$745
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Wed 7/8
6:01 am-12:36 am
1 stop21h 35m
San Francisco
Tue 7/14
7:45 am-5:55 pm
3 stops31h 10m
$747
Quickest round-trip
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Fri 9/18
1:45 pm-1:24 am
1 stop14h 39m
San Francisco
Sun 9/27
10:45 pm-12:20 pm
1 stop10h 35m
$783
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Wed 7/8
6:01 am-12:36 am
1 stop21h 35m
San Francisco
Tue 7/14
10:40 pm-3:21 pm
1 stop13h 41m
$794
Cheapest one-way
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Mon 7/13
10:19 am-12:18 am
2 stops40h 59m
$305
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Wed 5/13
10:19 am-9:55 pm
3 stops38h 36m
$317
Quickest one-way
Santo DomingoSan Francisco
SDQ - SFO
SDQSFO
Santo Domingo Las Americas
Wed 8/26
4:44 pm-11:50 pm
1 stop10h 06m
$373
Showing 1-10 of 16 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santo Domingo with our price prediction graph.
SDQ-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to San Francisco
What is the cheapest month to book a flight from Santo Domingo to San Francisco?
Currently, June is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $498). Flying from Santo Domingo to San Francisco in April is currently the most expensive (average of $783). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santo Domingo to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 28, 2026.
Peruse reviews from past customers who have flown with JetBlue from Santo Domingo to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.3
Crew
7.9
Overall
7.2
Comfort
7.5
Entertainment
7.2
Food
6.6
Reviews
1 / 20
6.0
GoodAnonymous,Mar 2026
FLL - ORH
Boarding
7.3
Crew
7.9
Overall
7.2
Comfort
7.5
Entertainment
7.2
Food
6.6
Reviews
1 / 20
6.0
GoodAnonymous,Mar 2026
FLL - ORH
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
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Santo Domingo and San Francisco flights
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Browse through other flights departing from Santo Domingo. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
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Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Top airline flying from Santo Domingo to San Francisco
Discover the top airline that operate flights from Santo Domingo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$458 | Average$564 | FlexibilityNo cancel fee | On-time62% |