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$292+ Cheap flights from North Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SCL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from North Carolina to Santiago

Keep the following information in mind while searching for North Carolina to Santiago flight deals. Data was last updated September 15, 2025.

Round-trip from

$567
(Kiwi.com)

One-way from

$292
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$753
From North Carolina to Santiago Arturo Merino Benitez
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One-way flight from North Carolina to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 3% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from North Carolina to Santiago

Cheapest flights from North Carolina to Santiago
Explore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/131:51 pmRDU - SCL
2 stops23h 54mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$567
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:51 pmRDU - SCL
2 stops23h 54mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$570
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/91:51 pmRDU - SCL
2 stops31h 24mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$611
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:32 amCLT - SCL
2 stops26h 08mMultiple Airlines
Tue 12/29:10 pmSCL - CLT
2 stops20h 51mMultiple Airlines
Deal found 9/13$612
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:30 amRDU - SCL
2 stops21h 45mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$618
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/101:51 pmRDU - SCL
2 stops23h 54mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$633
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/131:51 pmRDU - SCL
2 stops31h 24mMultiple Airlines
Sat 10/1810:55 pmSCL - RDU
1 stop15h 01mMultiple Airlines
Deal found 9/12$639
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:51 pmRDU - SCL
2 stops23h 54mMultiple Airlines
Sat 10/1810:55 pmSCL - RDU
1 stop15h 01mMultiple Airlines
Deal found 9/12$643
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/41:50 pmCLT - SCL
2 stops31h 25mMultiple Airlines
Wed 10/811:00 amSCL - CLT
1 stop26h 39mMultiple Airlines
Deal found 9/14$645
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:07 pmRDU - SCL
2 stops37h 08mMultiple Airlines
Wed 10/2211:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$654
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:30 amRDU - SCL
2 stops23h 30mMultiple Airlines
Thu 10/2311:00 amSCL - RDU
1 stop26h 56mMultiple Airlines
Deal found 9/12$658
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:11 pmCLT - SCL
1 stop17h 34mLATAM Airlines
Tue 10/1410:55 pmSCL - CLT
1 stop15h 28mLATAM Airlines
Deal found 9/13$684

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from North Carolina to Santiago that are best for you.

Fly from

North Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 11/24

10:32 am-12:15 pm

3 stops23h 43m

Santiago Arturo Merino Benitez

Tue 12/2

9:10 pm-4:01 pm

2 stops20h 51m

$612

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 10/4

5:45 am-5:01 am

3 stops22h 16m

Santiago Arturo Merino Benitez

Wed 10/8

5:55 am-12:39 pm

2 stops31h 44m

$646

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 10/14

2:27 pm-6:00 am

2 stops14h 33m

Santiago Arturo Merino Benitez

Tue 10/21

10:55 pm-1:23 pm

1 stop15h 28m

$688

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 10/14

5:45 am-9:55 pm

3 stops39h 10m

Santiago Arturo Merino Benitez

Mon 10/20

12:55 am-11:28 pm

2 stops23h 33m

$692

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/3

1:22 pm-6:55 am

1 stop15h 33m

Santiago Arturo Merino Benitez

Tue 12/9

11:40 pm-1:28 pm

1 stop15h 48m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 12/4

1:22 pm-6:55 am

1 stop15h 33m

Santiago Arturo Merino Benitez

Tue 12/9

8:50 pm-1:28 pm

2 stops18h 38m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/3

11:38 am-4:30 am

2 stops14h 52m

Santiago Arturo Merino Benitez

Thu 12/11

11:40 pm-1:28 pm

1 stop15h 48m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 10/28

1:15 pm-5:55 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Tue 11/4

11:10 pm-11:00 am

1 stop13h 50m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 11/24

2:12 pm-7:00 am

2 stops14h 48m

Santiago Arturo Merino Benitez

Mon 12/1

12:25 am-6:26 pm

2 stops20h 01m

$703

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 11/26

2:12 pm-7:00 am

2 stops14h 48m

Santiago Arturo Merino Benitez

Mon 12/1

11:25 pm-6:26 pm

2 stops21h 01m

$703

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 54 results
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Best time to book a flight from North Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santiago

What is the cheapest month to book a flight from North Carolina to Santiago?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $752). Flying from North Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SCL?

Find hourly flight availability from North Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from North Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from North Carolina?

    If you book a flight to Santiago from North Carolina, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from North Carolina to Santiago?

    There are many flights that can get you from North Carolina to Santiago in 14h 10m. Fly via LATAM Airlines, Delta, or United Airlines to get the fastest option. North Carolina and Santiago are separated by a distance of 4811 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Santiago one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $524. United Airlines flights start at $524 while deals on American Airlines start at $558 one-way.

  • What are the most popular routes from North Carolina to Santiago?

    The most popular route from North Carolina to Santiago is Charlotte Douglas - Santiago Arturo Merino Benitez. You may also consider Raleigh-Durham - Santiago Arturo Merino Benitez or Norfolk - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from North Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santiago.

  • Can I find deals for business class flights from North Carolina to Santiago?

    Yes. Cheapflights offers flight deals from North Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santiago?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $752). Flying from North Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Santiago

Discover the top 4 airlines that operate flights from North Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$418Average$575FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$505Average$938FlexibilityNo cancel feeOn-time71%
DeltaCheapest$608Average$990FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$683Average$935FlexibilityNo cancel feeOn-time81%

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