Santiago

$263+ Cheap flights from North Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SCL
Oct 16 — Oct 231
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Santiago

Keep the following information in mind while searching for North Carolina to Santiago flight deals. Data was last updated September 16, 2025.

Round-trip from

$591
(Mytrip)

One-way from

$263
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$753
From North Carolina to Santiago Arturo Merino Benitez
One-way flight from North Carolina to Santiago Arturo Merino Benitez
Highest demand for flights based on searches. 3% potential increase in price ($34 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from North Carolina to Santiago

Cheapest flights from North Carolina to Santiago
Explore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/291:50 pmCLT - SCL
2 stops23h 55mMultiple Airlines
Thu 10/23:30 pmSCL - CLT
3 stops32h 29mMultiple Airlines
Deal found 9/15$591
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:22 pmCLT - SCL
3 stops26h 53mMultiple Airlines
Tue 11/1812:30 pmSCL - CLT
2 stops29h 31mMultiple Airlines
Deal found 9/16$610
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:51 pmRDU - SCL
2 stops39h 09mMultiple Airlines
Sun 10/2610:50 amSCL - RDU
1 stop27h 06mMultiple Airlines
Deal found 9/15$632
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/131:51 pmRDU - SCL
3 stops21h 29mMultiple Airlines
Sun 10/2610:50 amSCL - RDU
1 stop27h 06mMultiple Airlines
Deal found 9/15$634
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:42 pmCLT - SCL
2 stops21h 33mMultiple Airlines
Sun 11/2310:50 amSCL - CLT
1 stop31h 11mMultiple Airlines
Deal found 9/15$637
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:42 pmCLT - SCL
2 stops21h 33mMultiple Airlines
Sun 11/1611:25 pmSCL - CLT
1 stop24h 32mMultiple Airlines
Deal found 9/15$644
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/41:50 pmCLT - SCL
2 stops31h 25mMultiple Airlines
Wed 10/811:00 amSCL - CLT
1 stop26h 39mMultiple Airlines
Deal found 9/14$645
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:11 pmCLT - SCL
2 stops29h 19mMultiple Airlines
Sat 12/610:35 amSCL - CLT
1 stop23h 40mMultiple Airlines
Deal found 9/15$661
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:25 pmRDU - SCL
1 stop16h 20mLATAM Airlines
Wed 10/1510:55 pmSCL - RDU
1 stop16h 15mLATAM Airlines
Deal found 9/15$684
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:50 pmRDU - SCL
1 stop14h 05mLATAM Airlines
Sun 12/1410:35 amSCL - RDU
2 stops15h 44mLATAM Airlines
Deal found 9/14$698
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:35 pmRDU - SCL
1 stop14h 10mLATAM Airlines
Tue 10/214:40 amSCL - RDU
2 stops16h 45mLATAM Airlines
Deal found 9/16$699
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1210:00 amRDU - SCL
1 stop18h 45mLATAM Airlines
Sun 10/2610:30 pmSCL - RDU
1 stop16h 40mLATAM Airlines
Deal found 9/16$703

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from North Carolina to Santiago that are best for you.

Fly from

North Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/29

1:50 pm-2:45 pm

2 stops23h 55m

Santiago Arturo Merino Benitez

Thu 10/2

3:30 pm-10:59 pm

3 stops32h 29m

$591

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Fri 11/14

5:22 pm-10:15 pm

3 stops26h 53m

Santiago Arturo Merino Benitez

Tue 11/18

12:30 pm-4:01 pm

2 stops29h 31m

$610

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Fri 11/14

10:42 pm-10:15 pm

2 stops21h 33m

Santiago Arturo Merino Benitez

Sun 11/23

10:50 am-9:09 am

1 stop24h 19m

$652

RaleighSantiago

RDU - SCL

RDUSCL

Raleigh-Durham

Tue 10/14

2:35 pm-5:45 am

1 stop14h 10m

Santiago Arturo Merino Benitez

Tue 10/21

10:55 pm-2:10 pm

1 stop16h 15m

$684

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 10/14

2:27 pm-6:00 am

2 stops14h 33m

Santiago Arturo Merino Benitez

Tue 10/21

10:55 pm-1:23 pm

1 stop15h 28m

$688

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 10/14

5:45 am-9:55 pm

3 stops39h 10m

Santiago Arturo Merino Benitez

Mon 10/20

12:55 am-11:28 pm

2 stops23h 33m

$692

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 12/1

2:12 pm-7:00 am

2 stops14h 48m

Santiago Arturo Merino Benitez

Mon 12/15

10:35 am-11:48 pm

2 stops15h 13m

$693

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 12/4

1:22 pm-6:55 am

1 stop15h 33m

Santiago Arturo Merino Benitez

Tue 12/9

8:50 pm-1:28 pm

2 stops18h 38m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/3

1:22 pm-6:55 am

1 stop15h 33m

Santiago Arturo Merino Benitez

Thu 12/11

8:10 am-11:48 pm

2 stops17h 38m

$699

RaleighSantiago

RDU - SCL

RDUSCL

Raleigh-Durham

Wed 10/15

8:10 am-6:00 am

1 stop20h 50m

Santiago Arturo Merino Benitez

Wed 10/22

10:55 pm-2:10 pm

1 stop16h 15m

$699

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 51 results
1
2
3
...
6

Best time to book a flight from North Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santiago

What is the cheapest month to book a flight from North Carolina to Santiago?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $752). Flying from North Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SCL?

Find hourly flight availability from North Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from North Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from North Carolina to Santiago?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santiago from North Carolina?

    If you book a flight to Santiago from North Carolina, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from North Carolina to Santiago?

    There are many flights that can get you from North Carolina to Santiago in 12h 39m. Fly via LATAM Airlines, Copa Airlines, or Delta to get the fastest option. North Carolina and Santiago are separated by a distance of 4811 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Santiago one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $503. American Airlines flights start at $518 while deals on United Airlines start at $524 one-way.

  • What are the most popular routes from North Carolina to Santiago?

  • Can I find deals for flights from North Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santiago.

  • Can I find deals for business class flights from North Carolina to Santiago?

    Yes. Cheapflights offers flight deals from North Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santiago?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $752). Flying from North Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from North Carolina to Santiago

Discover the top 4 airlines that operate flights from North Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$418Average$575FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$505Average$937FlexibilityNo cancel feeOn-time71%
DeltaCheapest$608Average$989FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$683Average$934FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.