$294+ Cheap flights from North Carolina to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SCL
Aug 4 — Aug 111
1 adult, Economy
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Find cheap flights from North Carolina to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to Santiago
Keep the following information in mind while searching for North Carolina to Santiago flight deals. Data was last updated July 30, 2025.
Round-trip from | $508 (Mytrip) |
|---|---|
One-way from | $243 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $858 |
Find flight deals from North Carolina to Santiago
Cheapest flights from North Carolina to SantiagoExplore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.
Explore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/111:28 pmCLT - SCL
2 stops23h 57mMultiple Airlines
Thu 9/183:30 pmSCL - CLT
2 stops21h 53mMultiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$508
This LATAM Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:06 pmRDU - SCL
1 stop16h 44mLATAM Airlines
Tue 9/2311:55 pmSCL - RDU
1 stop15h 22mLATAM Airlines
Deal found 7/30![LATAM Airlines logo]()
$646
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:30 pmRDU - SCL
1 stop34h 30mDelta
Tue 12/26:30 pmSCL - RDU
2 stops24h 31mDelta
Deal found 7/29![Delta logo]()
$681
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:01 amORF - SCL
2 stops19h 09mMultiple Airlines
Wed 11/2612:45 amSCL - ORF
2 stops23h 58mMultiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$706
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/202:00 pmCLT - SCL
2 stops16h 00mLATAM Airlines
Wed 8/2711:05 pmSCL - CLT
2 stops18h 43mLATAM Airlines
Deal found 7/30![LATAM Airlines logo]()
$719
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/299:43 pmRDU - SCL
2 stops23h 32mMultiple Airlines
Thu 9/43:20 amSCL - RDU
2 stops15h 14mMultiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$738
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:23 pmORF - SCL
1 stop14h 27mAmerican Airlines
Wed 12/1011:15 pmSCL - ORF
1 stop16h 49mAmerican Airlines
Deal found 7/28![American Airlines logo]()
$754
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:37 pmRDU - SCL
2 stops15h 13mAmerican Airlines
Tue 1/1310:15 pmSCL - RDU
1 stop19h 36mAmerican Airlines
Deal found 7/29![American Airlines logo]()
$766
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/269:45 amORF - SCL
3 stops23h 20mLATAM Airlines
Wed 12/105:15 amSCL - ORF
2 stops20h 46mLATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:05 pmORF - SCL
2 stops34h 45mUnited Airlines
Thu 11/2710:45 pmSCL - ORF
2 stops22h 03mUnited Airlines
Deal found 7/29![United Airlines logo]()
$828
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/187:16 pmTYS - SCL
1 stop11h 44mLATAM Airlines
Fri 8/224:55 pmSCL - TYS
2 stops17h 32mLATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$834
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1812:03 pmTYS - SCL
2 stops18h 52mAmerican Airlines
Fri 8/229:55 pmSCL - TYS
2 stops21h 50mAmerican Airlines
Deal found 7/30![American Airlines logo]()
$848
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from North Carolina to Santiago that are best for you.
Fly from
North Carolina
Fly to
Santiago
Route
Depart
Return
Price
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Thu 9/11
1:28 pm-2:25 pm
2 stops23h 57m
Santiago Arturo Merino Benitez
Thu 9/18
3:30 pm-12:23 pm
2 stops21h 53m
$508
RaleighSantiago
RDU - SCL
RDUSCL
Raleigh-Durham
Wed 9/10
2:06 pm-7:50 am
1 stop16h 44m
Santiago Arturo Merino Benitez
Tue 9/23
11:55 pm-2:17 pm
1 stop15h 22m
$646
RaleighSantiago
RDU - SCL
RDUSCL
Raleigh-Durham
Sun 11/23
6:30 pm-7:00 am
1 stop34h 30m
Santiago Arturo Merino Benitez
Mon 12/1
6:30 pm-12:49 pm
2 stops20h 19m
$681
NorfolkSantiago
ORF - SCL
ORFSCL
Norfolk
Mon 11/17
8:01 am-5:10 am
2 stops19h 09m
Santiago Arturo Merino Benitez
Wed 11/26
12:45 am-10:43 pm
2 stops23h 58m
$706
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Wed 8/20
2:00 pm-6:00 am
2 stops16h 00m
Santiago Arturo Merino Benitez
Wed 8/27
11:05 pm-5:48 pm
2 stops18h 43m
$719
RaleighSantiago
RDU - SCL
RDUSCL
Raleigh-Durham
Fri 8/29
9:43 pm-9:15 pm
2 stops23h 32m
Santiago Arturo Merino Benitez
Thu 9/4
3:20 am-6:34 pm
2 stops15h 14m
$738
NorfolkSantiago
ORF - SCL
ORFSCL
Norfolk
Wed 11/26
3:23 pm-7:50 am
1 stop14h 27m
Santiago Arturo Merino Benitez
Wed 12/10
11:15 pm-2:04 pm
1 stop16h 49m
$754
RaleighSantiago
RDU - SCL
RDUSCL
Raleigh-Durham
Tue 12/9
2:37 pm-7:50 am
2 stops15h 13m
Santiago Arturo Merino Benitez
Tue 1/13
10:15 pm-3:51 pm
1 stop19h 36m
$766
WilmingtonSantiago
ILM - SCL
ILMSCL
Wilmington New Hanover County
Sun 1/18
6:43 am-7:50 am
1 stop23h 07m
Santiago Arturo Merino Benitez
Thu 2/5
11:15 pm-3:57 pm
1 stop18h 42m
$794
NorfolkSantiago
ORF - SCL
ORFSCL
Norfolk
Wed 11/26
9:45 am-11:05 am
3 stops23h 20m
Santiago Arturo Merino Benitez
Wed 12/10
5:15 am-12:01 am
2 stops20h 46m
$794
Showing 1-10 of 50 results
Best time to book a flight from North Carolina to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Santiago
What is the cheapest month to book a flight from North Carolina to Santiago?
Currently, April is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $752). Flying from North Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to SCL?
Find hourly flight availability from North Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.
When flying from North Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 30, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and Qantas Airways from North Carolina to Santiago by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Comfort
7.9
Overall
8.0
Entertainment
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for North Carolina to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from North Carolina to Santiago
Discover the top 4 airlines that operate flights from North Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$418 | Average$641 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$640 | Average$1,006 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$683 | Average$953 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$726 | Average$974 | FlexibilityNo cancel fee | On-time71% |