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$262+ Cheap flights from North Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SCL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from North Carolina to Santiago

Cheapest flights from North Carolina to Santiago
Explore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:14 pmRDU - SCL
2 stops31h 16mMultiple Airlines
Wed 12/1011:25 pmSCL - RDU
1 stop16h 56mMultiple Airlines
Deal found 12/2$614
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:48 pmRDU - SCL
1 stop14h 02mUnited Airlines
Tue 12/2310:45 pmSCL - RDU
1 stop14h 36mUnited Airlines
Deal found 12/3$706
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:22 pmRDU - SCL
2 stops30h 39mMultiple Airlines
Wed 2/2511:25 pmSCL - RDU
1 stop23h 05mMultiple Airlines
Deal found 12/3$710
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:12 pmRDU - SCL
1 stop15h 28mDelta
Sat 2/2811:10 pmSCL - RDU
1 stop12h 43mDelta
Deal found 12/3$714
This LATAM Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:05 amRDU - SCL
1 stop20h 55mLATAM Airlines
Mon 12/229:30 pmSCL - RDU
1 stop16h 26mLATAM Airlines
Deal found 12/3$716
This KAYAK deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:33 amCLT - SCL
2 stops22h 27mLATAM Airlines
Thu 12/2511:10 pmSCL - CLT
1 stop13h 43mLATAM Airlines
Deal found 12/1$719
This LATAM Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:30 amORF - SCL
2 stops21h 05mLATAM Airlines
Mon 12/1511:25 pmSCL - ORF
2 stops21h 09mLATAM Airlines
Deal found 12/2$719
This KAYAK deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amRDU - SCL
2 stops21h 35mLATAM Airlines
Thu 2/266:40 amSCL - RDU
2 stops17h 54mLATAM Airlines
Deal found 12/3$719
This LATAM Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:32 pmRDU - SCL
2 stops16h 28mLATAM Airlines
Sun 12/2111:10 pmSCL - RDU
1 stop13h 05mLATAM Airlines
Deal found 12/3$720
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:45 pmRDU - SCL
2 stops35h 05mUnited Airlines
Sat 12/2010:45 pmSCL - RDU
1 stop25h 14mUnited Airlines
Deal found 12/2$728
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:22 pmRDU - SCL
2 stops30h 39mMultiple Airlines
Sat 2/2811:25 pmSCL - RDU
1 stop23h 05mMultiple Airlines
Deal found 12/3$737
This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:32 pmRDU - SCL
3 stops23h 58mLATAM Airlines
Wed 12/177:15 amSCL - RDU
3 stops35h 32mLATAM Airlines
Deal found 12/2$763

Find flight deals from North Carolina to Santiago

Keep the following information in mind while searching for North Carolina to Santiago flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$593
(Mytrip)

One-way from

$262
(Mytrip)

Popular in

August

Cheapest in

October

Average price

$878
Provider with most accurate pricing for Raleigh-Durham-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santiago Arturo Merino Benitez flights.
Search Deals
From North Carolina to Santiago Arturo Merino Benitez
Search Deals
One-way flight from North Carolina to Santiago Arturo Merino Benitez
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from North Carolina to Santiago that are best for you.

Fly from

North Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 1/22

3:15 pm-10:15 pm

3 stops29h 00m

Santiago Arturo Merino Benitez

Mon 1/26

12:35 pm-10:55 am

2 stops24h 20m

$696

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

2:10 pm-6:55 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Mon 3/16

4:35 am-11:50 pm

2 stops20h 15m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 1/22

6:00 am-6:55 am

1 stop22h 55m

Santiago Arturo Merino Benitez

Mon 1/26

6:30 pm-10:50 am

2 stops18h 20m

$714

GreensboroSantiago

GSO - SCL

GSOSCL

Greensboro/H. Point

Mon 1/19

7:05 am-8:15 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Wed 2/11

10:30 pm-4:17 pm

1 stop19h 47m

$714

RaleighSantiago

RDU - SCL

RDUSCL

Raleigh-Durham

Thu 1/22

4:44 pm-8:50 am

1 stop14h 06m

Santiago Arturo Merino Benitez

Mon 1/26

10:45 pm-3:40 pm

1 stop18h 55m

$714

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/23

7:00 am-10:39 am

2 stops25h 39m

Santiago Arturo Merino Benitez

Sun 3/8

1:35 am-12:22 pm

3 stops35h 47m

$714

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 2/23

6:59 pm-3:30 pm

2 stops18h 31m

Santiago Arturo Merino Benitez

Mon 3/9

6:30 pm-4:24 pm

2 stops22h 54m

$714

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Mon 3/9

6:58 pm-2:05 pm

2 stops18h 07m

Santiago Arturo Merino Benitez

Mon 3/16

5:15 am-11:59 pm

2 stops19h 44m

$714

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Thu 3/19

12:28 pm-5:55 am

1 stop16h 27m

Santiago Arturo Merino Benitez

Wed 3/25

10:10 pm-9:38 am

1 stop12h 28m

$714

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Thu 3/19

2:19 pm-7:40 am

1 stop16h 21m

Santiago Arturo Merino Benitez

Mon 3/23

3:00 pm-1:32 pm

2 stops23h 32m

$714

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 49 results
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Best time to book a flight from North Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santiago

What is the cheapest month to book a flight from North Carolina to Santiago?

Currently, July is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $400). Flying from North Carolina to Santiago in June is currently the most expensive (average of $752). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SCL?

Find hourly flight availability from North Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

When flying from North Carolina to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the afternoon.

What is the cheapest day to fly from North Carolina to Santiago?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Santiago flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from North Carolina?

    If you book a flight to Santiago from North Carolina, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from North Carolina to Santiago?

    There are many flights that can get you from North Carolina to Santiago in 14h 45m. Fly via LATAM Airlines, Delta, or American Airlines to get the fastest option. North Carolina and Santiago are separated by a distance of 4783 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Santiago one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $492. American Airlines flights start at $518 while deals on Delta start at $518 one-way.

  • What are the most popular routes from North Carolina to Santiago?

    The most popular route from North Carolina to Santiago is Raleigh-Durham - Santiago Arturo Merino Benitez. You may also consider Charlotte Douglas - Santiago Arturo Merino Benitez or Myrtle Beach Intl - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from North Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santiago.

  • Can I find deals for business class flights from North Carolina to Santiago?

    Yes. Cheapflights offers flight deals from North Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santiago?

    Currently, July is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $400). Flying from North Carolina to Santiago in June is currently the most expensive (average of $752). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Santiago

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Top 4 airlines flying from North Carolina to Santiago

Discover the top 4 airlines that operate flights from North Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$505Average$898FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$523Average$910FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$569Average$905FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$992FlexibilityNo cancel feeOn-timeN/A

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