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$277+ Cheap flights from North Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SCL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from North Carolina to Santiago

Keep the following information in mind while searching for North Carolina to Santiago flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$541
(Kiwi.com)

One-way from

$277
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$929
Provider with most accurate pricing for Raleigh-Durham-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Santiago Arturo Merino Benitez flights.
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From North Carolina to Santiago Arturo Merino Benitez
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One-way flight from North Carolina to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from North Carolina to Santiago

Cheapest flights from North Carolina to Santiago
Explore the most affordable flight options available from North Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:21 pmRDU - SCL
2 stops28h 54mMultiple Airlines
Thu 12/1111:25 pmSCL - RDU
1 stop16h 56mMultiple Airlines
Deal found 11/4$541
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/99:38 pmCLT - SCL
2 stops30h 12mMultiple Airlines
Tue 11/119:05 pmSCL - CLT
2 stops17h 55mMultiple Airlines
Deal found 11/5$569
This FlightHub deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:50 pmRDU - SCL
1 stop14h 05mLATAM Airlines
Thu 12/1111:30 pmSCL - RDU
1 stop16h 39mLATAM Airlines
Deal found 11/5$670
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:25 pmRDU - SCL
2 stops17h 15mMultiple Airlines
Mon 11/2411:25 pmSCL - RDU
1 stop23h 25mMultiple Airlines
Deal found 11/4$672
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:22 pmCLT - SCL
1 stop15h 33mLATAM Airlines
Tue 12/911:30 pmSCL - CLT
1 stop15h 58mLATAM Airlines
Deal found 11/4$684
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:47 pmRDU - SCL
1 stop14h 08mLATAM Airlines
Mon 11/2411:30 pmSCL - RDU
1 stop16h 37mLATAM Airlines
Deal found 11/4$685
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:53 pmRDU - SCL
1 stop13h 07mAmerican Airlines
Tue 12/910:30 pmSCL - RDU
2 stops16h 08mAmerican Airlines
Deal found 11/5$704
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:23 amILM - SCL
1 stop19h 17mDelta
Mon 11/178:15 amSCL - ILM
2 stops17h 00mDelta
Deal found 11/4$714
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:48 pmCLT - SCL
1 stop14h 02mUnited Airlines
Mon 12/110:45 pmSCL - CLT
1 stop19h 04mUnited Airlines
Deal found 11/6$714
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:24 amORF - SCL
2 stops18h 11mDelta
Wed 12/105:25 pmSCL - ORF
2 stops20h 07mDelta
Deal found 11/5$714
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:25 amILM - SCL
2 stops24h 25mUnited Airlines
Mon 11/1710:45 pmSCL - ILM
2 stops27h 05mUnited Airlines
Deal found 11/5$719
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:43 pmORF - SCL
2 stops35h 17mLATAM Airlines
Thu 11/2711:10 pmSCL - ORF
1 stop14h 07mLATAM Airlines
Deal found 11/5$719

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from North Carolina to Santiago that are best for you.

Fly from

North Carolina

Fly to

Santiago

Route

Depart

Return

Price

RaleighSantiago

RDU - SCL

RDUSCL

Raleigh-Durham

Thu 12/4

2:50 pm-6:55 am

1 stop14h 05m

Santiago Arturo Merino Benitez

Thu 12/11

10:35 am-12:18 am

2 stops15h 43m

$674

RaleighSantiago

RDU - SCL

RDUSCL

Raleigh-Durham

Thu 12/4

3:21 pm-7:00 am

1 stop13h 39m

Santiago Arturo Merino Benitez

Wed 12/10

4:35 am-2:21 pm

2 stops35h 46m

$691

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Tue 11/18

2:23 pm-7:40 am

1 stop15h 17m

Santiago Arturo Merino Benitez

Wed 11/26

6:35 pm-12:35 pm

2 stops20h 00m

$714

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 12/9

4:51 pm-8:50 am

1 stop13h 59m

Santiago Arturo Merino Benitez

Wed 12/17

10:45 pm-10:41 am

1 stop13h 56m

$714

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Thu 1/15

2:32 pm-7:40 am

1 stop15h 08m

Santiago Arturo Merino Benitez

Thu 1/22

9:30 pm-9:42 am

1 stop14h 12m

$714

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 11/26

4:48 pm-8:50 am

1 stop14h 02m

Santiago Arturo Merino Benitez

Mon 12/1

10:45 pm-3:49 pm

1 stop19h 04m

$714

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

12:57 pm-7:00 am

1 stop16h 03m

Santiago Arturo Merino Benitez

Mon 3/16

6:30 pm-1:35 pm

2 stops20h 05m

$714

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Tue 11/18

2:23 pm-7:40 am

1 stop15h 17m

Santiago Arturo Merino Benitez

Wed 11/26

11:10 pm-12:35 pm

1 stop15h 25m

$714

NorfolkSantiago

ORF - SCL

ORFSCL

Norfolk

Wed 11/26

8:30 am-6:35 am

2 stops20h 05m

Santiago Arturo Merino Benitez

Wed 12/10

11:30 pm-11:33 am

1 stop14h 03m

$714

NorfolkSantiago

ORF - SCL

ORFSCL

Norfolk

Wed 11/26

10:24 am-6:35 am

2 stops18h 11m

Santiago Arturo Merino Benitez

Tue 12/9

4:35 am-12:32 am

2 stops21h 57m

$714

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 45 results
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Best time to book a flight from North Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santiago

What is the cheapest month to book a flight from North Carolina to Santiago?

Currently, July is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $400). Flying from North Carolina to Santiago in June is currently the most expensive (average of $752). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SCL?

Find hourly flight availability from North Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

When flying from North Carolina to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the afternoon.

What is the cheapest day to fly from North Carolina to Santiago?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Santiago flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from North Carolina?

    If you book a flight to Santiago from North Carolina, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from North Carolina to Santiago?

    There are many flights that can get you from North Carolina to Santiago in 13h 59m. Fly via LATAM Airlines, Delta, or United Airlines to get the fastest option. North Carolina and Santiago are separated by a distance of 4783 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to Santiago one-way?

    To fly one-way, consider booking your trip with Air Canada, which is currently one of the cheapest options available, starting at $465. LATAM Airlines flights start at $494 while deals on Delta start at $518 one-way.

  • What are the most popular routes from North Carolina to Santiago?

    The most popular route from North Carolina to Santiago is Charlotte Douglas - Santiago Arturo Merino Benitez. You may also consider Raleigh-Durham - Santiago Arturo Merino Benitez or Norfolk - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from North Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santiago.

  • Can I find deals for business class flights from North Carolina to Santiago?

    Yes. Cheapflights offers flight deals from North Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santiago?

    Currently, July is the cheapest month in which you can book a flight from North Carolina to Santiago (average of $400). Flying from North Carolina to Santiago in June is currently the most expensive (average of $752). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Santiago

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Top 4 airlines flying from North Carolina to Santiago

Discover the top 4 airlines that operate flights from North Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$459Average$795FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$505Average$913FlexibilityNo cancel feeOn-time71%
DeltaCheapest$608Average$995FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$634Average$926FlexibilityNo cancel feeOn-time81%

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