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$406+ Cheap flights from Iowa to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Iowa to Santiago

Keep the following information in mind while searching for Iowa to Santiago flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$825
(United Airlines)

One-way from

$406
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$914
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
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From Iowa to Santiago Arturo Merino Benitez
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One-way flight from Iowa to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($63 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Iowa to Santiago

Cheapest flights from Iowa to Santiago
Explore the most affordable flight options available from Iowa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Orbitz deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:55 pmOMA - SCL
1 stop34h 45mLATAM Airlines
Sun 11/3011:10 pmSCL - OMA
1 stop28h 04mLATAM Airlines
Deal found 11/5$842
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:20 pmOMA - SCL
2 stops35h 30mUnited Airlines
Sun 12/2810:45 pmSCL - OMA
1 stop26h 37mUnited Airlines
Deal found 11/6$966
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:45 pmOMA - SCL
2 stops35h 05mUnited Airlines
Sun 11/3010:45 pmSCL - OMA
2 stops38h 46mUnited Airlines
Deal found 11/5$973
This Ovago deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:00 amOMA - SCL
1 stop21h 40mLATAM Airlines
Sun 12/289:30 pmSCL - OMA
1 stop16h 24mLATAM Airlines
Deal found 11/6$1,073
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:39 pmDSM - SCL
1 stop13h 16mAmerican Airlines
Mon 11/1711:15 pmSCL - DSM
1 stop20h 36mAmerican Airlines
Deal found 11/6$1,084
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:50 pmDSM - SCL
2 stops35h 00mUnited Airlines
Mon 11/1710:45 pmSCL - DSM
2 stops21h 40mUnited Airlines
Deal found 11/6$1,089
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:46 pmDSM - SCL
2 stops59h 04mUnited Airlines
Sun 12/2810:45 pmSCL - DSM
2 stops18h 48mUnited Airlines
Deal found 11/5$1,106
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:33 pmMLI - SCL
2 stops36h 17mUnited Airlines
Thu 1/810:45 pmSCL - MLI
2 stops38h 27mUnited Airlines
Deal found 11/4$1,152
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:08 pmMLI - SCL
2 stops19h 07mDelta
Fri 12/128:55 amSCL - MLI
2 stops34h 24mDelta
Deal found 11/4$1,164
This LATAM Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:50 amCID - SCL
2 stops21h 35mLATAM Airlines
Fri 12/1210:25 pmSCL - CID
2 stops26h 54mLATAM Airlines
Deal found 11/5$1,164
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:46 pmDSM - SCL
2 stops59h 04mUnited Airlines
Sat 12/2710:45 pmSCL - DSM
1 stop18h 34mUnited Airlines
Deal found 11/5$1,200
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/221:00 pmMLI - SCL
2 stops40h 50mUnited Airlines
Thu 1/810:45 pmSCL - MLI
2 stops38h 27mUnited Airlines
Deal found 11/4$1,218

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Iowa

Fly to

Santiago

Route

Depart

Return

Price

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 1/4

5:15 pm-8:50 am

2 stops36h 35m

Santiago Arturo Merino Benitez

Fri 1/23

10:45 pm-2:25 pm

2 stops18h 40m

$825

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 11/16

5:55 pm-7:40 am

1 stop34h 45m

Santiago Arturo Merino Benitez

Sun 11/30

11:10 pm-12:14 am

1 stop28h 04m

$842

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 1/4

3:08 pm-4:30 am

2 stops34h 22m

Santiago Arturo Merino Benitez

Thu 1/22

4:35 am-11:02 am

2 stops33h 27m

$899

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 12/21

6:20 pm-8:50 am

2 stops35h 30m

Santiago Arturo Merino Benitez

Sun 12/28

10:45 pm-10:22 pm

1 stop26h 37m

$966

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 11/16

6:45 pm-8:50 am

2 stops35h 05m

Santiago Arturo Merino Benitez

Sun 11/30

10:45 pm-10:31 am

2 stops38h 46m

$973

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 12/21

7:00 am-7:40 am

1 stop21h 40m

Santiago Arturo Merino Benitez

Sun 12/28

9:30 pm-10:54 am

1 stop16h 24m

$1,073

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 1/4

7:00 am-2:05 pm

2 stops28h 05m

Santiago Arturo Merino Benitez

Thu 1/22

12:20 am-10:21 pm

3 stops25h 01m

$1,104

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 12/21

6:46 pm-8:50 am

2 stops59h 04m

Santiago Arturo Merino Benitez

Sun 12/28

10:45 pm-2:33 pm

2 stops18h 48m

$1,106

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Tue 12/23

5:33 pm-8:50 am

2 stops36h 17m

Santiago Arturo Merino Benitez

Wed 1/7

10:45 pm-10:12 am

2 stops38h 27m

$1,152

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Mon 12/8

6:00 am-7:40 am

1 stop22h 40m

Santiago Arturo Merino Benitez

Thu 12/11

4:35 am-10:33 pm

2 stops20h 58m

$1,164

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 24 results
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Best time to book a flight from Iowa to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Santiago
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Iowa?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Iowa. Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • How long is the flight from Iowa to Santiago?

    Airlines like United Airlines, LATAM Airlines, and Delta fly from Iowa to Santiago in about 22h 40m. The time it takes to get you to your destination can typically vary by up to 13h 55m. The distance between Iowa and Santiago is about 5317 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Iowa to Santiago one-way?

    The cheapest airlines for a one-way flight from Iowa to Santiago are Delta ($583), United Airlines ($587), and LATAM Airlines ($591).

  • What are the most popular routes from Iowa to Santiago?

    The most popular flight routes from Iowa to Santiago are Cedar Rapids - Santiago Arturo Merino Benitez, Des Moines - Santiago Arturo Merino Benitez and Omaha Eppley Airfield - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Iowa to Santiago that include hotel bookings?

    Yes. In addition to deals on Iowa to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Santiago.

  • Can I find deals for business class flights from Iowa to Santiago?

    Yes. Cheapflights offers flight deals from Iowa to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Iowa to Santiago

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Top airline flying from Iowa to Santiago

Discover the top airline that operate flights from Iowa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$814Average$1,241FlexibilityNo cancel feeOn-time81%

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