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$539+ Cheap flights from Iowa to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Iowa to Santiago

Keep the following information in mind while searching for Iowa to Santiago flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$811
(American Airlines)

One-way from

$539
(Kiwi.com)
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
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From Iowa to Santiago Arturo Merino Benitez
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One-way flight from Iowa to Santiago Arturo Merino Benitez
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Find flight deals from Iowa to Santiago

Cheapest flights from Iowa to Santiago
Explore the most affordable flight options available from Iowa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:55 amOMA - SCL
2 stops23h 10mAmerican Airlines
Mon 11/311:45 pmSCL - OMA
1 stop21h 39mAmerican Airlines
Deal found 4/30$811
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1410:01 amCID - SCL
2 stops20h 04mAmerican Airlines
Sat 9/279:55 pmSCL - CID
2 stops22h 41mAmerican Airlines
Deal found 4/28$888
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:05 amOMA - SCL
1 stop18h 55mDelta
Sun 11/212:30 amSCL - OMA
2 stops23h 46mDelta
Deal found 4/29$914
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:45 amCID - SCL
2 stops22h 55mDelta
Thu 9/251:40 amSCL - CID
2 stops22h 11mDelta
Deal found 4/28$914
This Netflights deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Netflights is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:30 pmOMA - SCL
2 stops20h 55mLATAM Airlines
Sun 11/212:30 amSCL - OMA
3 stops26h 26mLATAM Airlines
Deal found 4/30$1,000
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/123:48 pmDSM - SCL
3 stops28h 27mMultiple Airlines
Thu 6/196:10 amSCL - DSM
3 stops38h 30mMultiple Airlines
Deal found 4/30$1,080
This LATAM Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/122:20 pmDSM - SCL
1 stop15h 40mLATAM Airlines
Thu 6/195:35 amSCL - DSM
2 stops18h 28mLATAM Airlines
Deal found 4/30$1,104
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1410:18 amDSM - SCL
2 stops19h 12mDelta
Sat 6/2111:05 pmSCL - DSM
2 stops23h 03mDelta
Deal found 4/29$1,188
This Air Canada deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:00 amOMA - SCL
2 stops20h 00mAir Canada
Mon 1/58:50 pmSCL - OMA
2 stops20h 36mAir Canada
Deal found 4/29$1,953
This Gotogate deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/148:00 amDSM - SCL
2 stops20h 04mCopa Airlines
Fri 6/2012:13 amSCL - DSM
2 stops18h 46mCopa Airlines
Deal found 4/29$2,351

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Iowa

Fly to

Santiago

Route

Depart

Return

Price

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

6:55 am-8:05 am

2 stops23h 10m

Santiago Arturo Merino Benitez

Mon 11/3

11:45 pm-6:24 pm

1 stop21h 39m

$811

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Sun 9/14

10:01 am-8:05 am

2 stops20h 04m

Santiago Arturo Merino Benitez

Sat 9/27

9:55 pm-6:36 pm

2 stops22h 41m

$888

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

11:05 am-8:00 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sun 11/2

12:30 am-9:16 pm

2 stops23h 46m

$914

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Fri 9/12

5:45 am-6:40 am

2 stops22h 55m

Santiago Arturo Merino Benitez

Thu 9/25

1:40 am-9:51 pm

2 stops22h 11m

$914

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

6:30 pm-5:25 pm

2 stops20h 55m

Santiago Arturo Merino Benitez

Sun 11/2

12:30 am-11:56 pm

3 stops26h 26m

$1,000

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/12

3:48 pm-9:15 pm

3 stops28h 27m

Santiago Arturo Merino Benitez

Thu 6/19

6:10 am-7:40 pm

3 stops38h 30m

$1,080

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/12

2:20 pm-7:00 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Thu 6/19

5:35 am-11:03 pm

2 stops18h 28m

$1,104

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sat 6/14

2:20 pm-7:00 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Sat 6/21

11:05 pm-11:03 pm

2 stops24h 58m

$1,188

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sat 6/14

8:00 am-5:04 am

2 stops20h 04m

Santiago Arturo Merino Benitez

Fri 6/20

12:13 am-5:59 pm

2 stops18h 46m

$2,351

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Fri 6/13

11:36 am-1:25 pm

3 stops24h 49m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 14 results
1
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Best time to book a flight from Iowa to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Santiago

What is the cheapest time of day to fly from IA to SCL?

Find hourly flight availability from Iowa to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Iowa to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 1, 2025.
See what other customers who have flown with Delta, KLM and LATAM Airlines from Iowa to Santiago have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,414 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Iowa?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Iowa. Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • What are the cheapest airlines to fly from Iowa to Santiago one-way?

    The cheapest airlines for a one-way flight from Iowa to Santiago are LATAM Airlines ($583), Delta ($743), and KLM ($4,705).

  • What are the most popular routes from Iowa to Santiago?

    The most popular flight routes from Iowa to Santiago are Des Moines - Santiago Arturo Merino Benitez, Cedar Rapids - Santiago Arturo Merino Benitez and Omaha Eppley Airfield - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Iowa to Santiago that include hotel bookings?

    Yes. In addition to deals on Iowa to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Santiago.

  • Can I find deals for business class flights from Iowa to Santiago?

    Yes. Cheapflights offers flight deals from Iowa to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Iowa to Santiago (average of $752). Flying from Iowa to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Santiago

Discover the top 2 airlines that operate flights from Iowa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$735Average$1,277FlexibilityNo cancel feeOn-time71%
DeltaCheapest$782Average$958FlexibilityNo cancel feeOn-timeN/A

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