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$661+ Cheap flights from Iowa to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
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Cheap flight deals from Iowa to Santiago

Cheapest flights from Iowa to Santiago
Explore the most affordable flight options available from Iowa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This KAYAK deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:50 pm
OMA
-
SCL
1 stop13h 50m
LATAM Airlines
Tue 12/229:30 pm
SCL
-
OMA
1 stop15h 31m
LATAM Airlines
Deal found 4/8$935
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:00 am
CID
-
SCL
2 stops41h 50m
Delta
Sun 11/811:25 pm
SCL
-
CID
2 stops25h 26m
Delta
Deal found 4/6$956
This BusinessClass deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:54 pm
OMA
-
SCL
2 stops34h 41m
LATAM Airlines
Mon 7/68:40 pm
SCL
-
OMA
1 stop14h 01m
LATAM Airlines
Deal found 4/8$1,012
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am
DSM
-
SCL
1 stop21h 50m
United Airlines
Sat 11/1410:45 pm
SCL
-
DSM
1 stop18h 35m
United Airlines
Deal found 4/8$1,025
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:00 am
OMA
-
SCL
2 stops23h 05m
American Airlines
Sat 6/139:00 pm
SCL
-
OMA
2 stops16h 57m
American Airlines
Deal found 4/7$1,040
This KAYAK deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:45 am
CID
-
SCL
1 stop22h 55m
LATAM Airlines
Sun 11/811:10 pm
SCL
-
CID
1 stop25h 41m
LATAM Airlines
Deal found 4/6$1,045
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:43 am
CID
-
SCL
2 stops18h 22m
American Airlines
Thu 5/289:00 pm
SCL
-
CID
2 stops26h 03m
American Airlines
Deal found 4/6$1,075
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:04 am
DSM
-
SCL
2 stops22h 46m
American Airlines
Mon 7/208:30 pm
SCL
-
DSM
2 stops23h 03m
American Airlines
Deal found 4/10$1,080
This Travelocity deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:15 pm
DSM
-
SCL
1 stop14h 25m
LATAM Airlines
Sat 11/1412:10 am
SCL
-
DSM
1 stop20h 32m
LATAM Airlines
Deal found 4/8$1,086
This Expedia deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:15 pm
OMA
-
SCL
3 stops31h 30m
LATAM Airlines
Sat 6/138:30 am
SCL
-
OMA
3 stops64h 20m
LATAM Airlines
Deal found 4/7$1,099
This LATAM Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:25 am
DSM
-
SCL
2 stops23h 10m
LATAM Airlines
Mon 7/208:40 pm
SCL
-
DSM
1 stop22h 13m
LATAM Airlines
Deal found 4/10$1,144
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:50 am
DSM
-
SCL
1 stop24h 15m
American Airlines
Mon 6/19:00 pm
SCL
-
DSM
1 stop27h 08m
American Airlines
Deal found 4/10$1,175

Find flight deals from Iowa to Santiago

Keep the following information in mind while searching for Iowa to Santiago flight deals. Data was last updated April 10, 2026.

Round-trip from

$1,012
(BusinessClass)

One-way from

$661
(SmartFares)

Popular in

December

Cheapest in

October

Average price

$1,169
From Iowa to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Iowa to Santiago Arturo Merino Benitez
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 6/28

5:54 pm-5:35 am

2 stops34h 41m

Santiago Arturo Merino Benitez

Mon 7/6

8:40 pm-9:41 am

1 stop14h 01m

$1,012

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Sun 6/28

6:19 am-7:05 am

2 stops23h 46m

Santiago Arturo Merino Benitez

Mon 7/6

8:30 pm-12:54 pm

2 stops17h 24m

$1,040

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Mon 6/1

1:15 pm-9:45 pm

3 stops31h 30m

Santiago Arturo Merino Benitez

Sat 6/13

8:30 am-11:50 pm

3 stops64h 20m

$1,099

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 5/25

5:50 am-7:05 am

1 stop24h 15m

Santiago Arturo Merino Benitez

Mon 6/1

9:00 pm-12:52 pm

2 stops16h 52m

$1,180

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Thu 5/21

5:45 am-7:15 am

1 stop24h 30m

Santiago Arturo Merino Benitez

Thu 5/28

8:40 pm-9:14 pm

1 stop25h 34m

$1,186

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Sat 5/23

5:47 am-7:15 am

1 stop24h 28m

Santiago Arturo Merino Benitez

Sat 5/30

8:40 pm-9:14 pm

1 stop25h 34m

$1,239

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 5/21

11:57 am-7:15 am

1 stop18h 18m

Santiago Arturo Merino Benitez

Thu 5/28

8:40 pm-11:08 am

1 stop15h 28m

$1,245
Quickest round-trip

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 5/21

2:33 pm-7:15 am

1 stop15h 42m

Santiago Arturo Merino Benitez

Thu 5/28

8:40 pm-1:37 pm

1 stop17h 57m

$1,265

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 5/7

11:57 am-7:15 am

1 stop18h 18m

Santiago Arturo Merino Benitez

Sun 5/10

7:55 pm-11:08 am

2 stops16h 13m

$1,267

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 5/25

11:57 am-10:49 am

3 stops21h 52m

Santiago Arturo Merino Benitez

Mon 6/1

11:00 pm-5:53 pm

2 stops19h 53m

$1,270

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/9

Showing 1-10 of 22 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Santiago
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Iowa?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Iowa. Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • How long is the flight from Iowa to Santiago?

    Airlines like LATAM Airlines, American Airlines, and Delta fly from Iowa to Santiago in about 15h 42m. The time it takes to get you to your destination can typically vary by up to 18h 59m. The distance between Iowa and Santiago is about 5374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Santiago?

    The most popular flight routes from Iowa to Santiago are Des Moines - Santiago Arturo Merino Benitez, Omaha Eppley Airfield - Santiago Arturo Merino Benitez and Cedar Rapids - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Iowa to Santiago that include hotel bookings?

    Yes. In addition to deals on Iowa to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Santiago.

  • Can I find deals for business class flights from Iowa to Santiago?

    Yes. Cheapflights offers flight deals from Iowa to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Iowa to Santiago

Discover the top airline that operate flights from Iowa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$814Average$1,203FlexibilityNo cancel feeOn-time81%

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