What are the cheapest airlines to fly from South Carolina to Santa Ana one-way?

One-way options have recently been found by users for as low as $51 on United Airlines. Other airlines that offer cheap prices include Spirit Airlines from $84 and Frontier from $90 one-way.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from South Carolina to Santa Ana?

The most popular flight routes from South Carolina to Santa Ana are Charlotte Douglas - Santa Ana J. Wayne/Orange Cnty, Greenville - Santa Ana J. Wayne/Orange Cnty and Charleston - Santa Ana J. Wayne/Orange Cnty.

What are the most popular airlines that fly from South Carolina to Santa Ana?

Before booking your flight from South Carolina to Santa Ana check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

How far in advance should I book a flight from South Carolina to Santa Ana?

To save on the cost of your flight from South Carolina to Santa Ana, book at least 13 days before your planned departure. Booking around this time can save you about 75% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $287 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $698.

What is the cheapest month to fly from South Carolina to Santa Ana?

Our data shows that September tends to be the cheapest month to fly to Santa Ana from South Carolina. Users have commonly found prices around $435 for the month, but tickets can be as low as $201. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to Santa Ana from South Carolina?

Most people fly into Santa Ana J. Wayne/Orange Cnty (SNA) if they book a flight to Santa Ana from South Carolina. J. Wayne/Orange Cnty is conveniently located just 4.8 mi from Santa Ana’s city center.

Can I find deals for flights from South Carolina to Santa Ana that include hotel bookings?

Yes. In addition to deals on South Carolina to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santa Ana.

Can I find deals for business class flights from South Carolina to Santa Ana?

Yes. Cheapflights offers flight deals from South Carolina to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$51+ Flights from South Carolina to Santa Ana

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Cheap flight deals from South Carolina to Santa Ana

Round-trip from	$111 (United Airlines)
One-way from	$51 (United Airlines)
Popular in	December
Cheapest in	September
Average price	$422

From South Carolina to Santa Ana J. Wayne/Orange Cnty

Search Deals

One-way flight from South Carolina to Santa Ana J. Wayne/Orange Cnty

Search Deals

Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Find flight deals from South Carolina to Santa Ana

Cheapest flights from South Carolina to Santa Ana
Explore the most affordable flight options available from South Carolina to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Tue 7/295:00 pmCLT - SNA

1 stop8h 00mUnited Airlines

Tue 8/56:45 amSNA - CLT

1 stop7h 27mUnited Airlines

Deal found 7/1

$111

Tue 7/299:21 amCLT - SNA

2 stops12h 42mSpirit Airlines

Mon 8/47:58 pmSNA - CLT

1 stop14h 42mSpirit Airlines

Deal found 7/1

$186

Sun 8/178:48 pmMYR - SNA

1 stop17h 41mSpirit Airlines

Sat 8/238:30 pmSNA - MYR

2 stops13h 43mSpirit Airlines

Deal found 7/1

$239

Fri 8/1510:38 amCHS - SNA

1 stop27h 51mSpirit Airlines

Fri 8/226:45 amSNA - CHS

2 stops10h 50mSpirit Airlines

Deal found 7/1

$314

Tue 8/126:03 pmCHS - SNA

1 stop19h 12mAlaska Airlines

Tue 8/199:15 pmSNA - CHS

1 stop17h 02mAlaska Airlines

Deal found 7/2

$318

Wed 7/303:25 pmCHS - SNA

1 stop9h 44mAmerican Airlines

Wed 8/612:28 pmSNA - CHS

1 stop6h 34mAmerican Airlines

Deal found 7/1

$319

Tue 8/126:20 amCHS - SNA

1 stop7h 33mDelta

Tue 8/197:12 pmSNA - CHS

2 stops13h 58mDelta

Deal found 7/2

$324

Wed 10/297:29 amGSP - SNA

1 stop9h 15mAmerican Airlines

Tue 11/412:44 pmSNA - GSP

1 stop8h 09mAmerican Airlines

Deal found 7/3

$351

Wed 8/65:23 amSAV - SNA

1 stop8h 27mDelta

Wed 8/136:45 amSNA - SAV

1 stop6h 15mDelta

Deal found 7/2

$351

Thu 9/45:20 pmGSP - SNA

1 stop7h 52mDelta

Sat 9/1312:13 pmSNA - GSP

1 stop8h 21mDelta

Deal found 7/2

$354

Wed 8/131:19 pmSAV - SNA

1 stop8h 54mAmerican Airlines

Sat 8/1611:26 amSNA - SAV

1 stop8h 32mAmerican Airlines

Deal found 7/1

$354

Mon 9/1511:40 amCAE - SNA

2 stops26h 58mSpirit Airlines

Fri 9/196:45 amSNA - CAE

3 stops25h 00mSpirit Airlines

Deal found 7/1

$363

Best flights from South Carolina to Santa Ana
Discover carefully curated flight deals from South Carolina to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Tue 7/295:00 pmCLT - SNA

1 stop8h 00mUnited Airlines

Tue 8/56:45 amSNA - CLT

1 stop7h 27mUnited Airlines

Deal found 7/1

$111

Tue 7/299:21 amCLT - SNA

2 stops12h 42mSpirit Airlines

Mon 8/47:58 pmSNA - CLT

1 stop14h 42mSpirit Airlines

Deal found 7/1

$186

Tue 8/126:03 pmCHS - SNA

1 stop19h 12mAlaska Airlines

Tue 8/199:15 pmSNA - CHS

1 stop17h 02mAlaska Airlines

Deal found 7/2

$318

Wed 7/303:25 pmCHS - SNA

1 stop9h 44mAmerican Airlines

Wed 8/612:28 pmSNA - CHS

1 stop6h 34mAmerican Airlines

Deal found 7/1

$319

Tue 8/126:20 amCHS - SNA

1 stop7h 33mDelta

Tue 8/197:12 pmSNA - CHS

2 stops13h 58mDelta

Deal found 7/2

$324

Sun 9/77:30 amSAV - SNA

2 stops17h 30mMultiple Airlines

Sat 9/136:45 amSNA - SAV

3 stops26h 19mMultiple Airlines

Deal found 7/2

$375

Thu 11/206:00 amCHS - SNA

2 stops9h 10mSouthwest

Sun 11/237:45 amSNA - CHS

2 stops8h 55mSouthwest

Deal found 7/1

$428

Sun 8/178:48 pmMYR - SNA

1 stop17h 41mSpirit Airlines

Sat 8/238:30 pmSNA - MYR

2 stops13h 43mSpirit Airlines

Deal found 7/1

$239

Fri 8/1510:38 amCHS - SNA

1 stop27h 51mSpirit Airlines

Fri 8/226:45 amSNA - CHS

2 stops10h 50mSpirit Airlines

Deal found 7/1

$314

Wed 10/297:29 amGSP - SNA

1 stop9h 15mAmerican Airlines

Tue 11/412:44 pmSNA - GSP

1 stop8h 09mAmerican Airlines

Deal found 7/3

$351

Wed 8/66:40 amSAV - SNA

1 stop7h 10mDelta

Tue 8/122:00 pmSNA - SAV

1 stop6h 59mDelta

Deal found 7/2

$351

Fri 8/154:25 pmGSP - SNA

1 stop7h 42mUnited Airlines

Mon 8/189:05 pmSNA - GSP

1 stop8h 46mUnited Airlines

Deal found 7/2

$378

Last-minute flights from South Carolina to Santa Ana
Discover last-minute flight deals from South Carolina to Santa Ana. Data last updated July 3, 2025 and is based on user searches.

Wed 7/97:29 amSAV - SNA

1 stop11h 18mAmerican Airlines

Sun 7/136:53 pmSNA - SAV

1 stop15h 30mAmerican Airlines

Deal found 7/3

$706

Wed 7/92:45 pmCHS - SNA

1 stop9h 10mSouthwest

Fri 7/118:30 amSNA - CHS

1 stop8h 55mSouthwest

Deal found 7/2

$752

Wed 7/912:10 pmSAV - SNA

2 stops13h 08mMultiple Airlines

Sun 7/133:32 pmSNA - SAV

2 stops19h 42mMultiple Airlines

Deal found 7/1

$776

Wed 7/910:50 amSAV - SNA

1 stop9h 15mSouthwest

Fri 7/117:00 amSNA - SAV

1 stop9h 10mSouthwest

Deal found 7/1

$782

Fri 7/119:28 pmCLT - SNA

1 stop16h 58mSpirit Airlines

Fri 7/187:58 pmSNA - CLT

1 stop14h 42mSpirit Airlines

Deal found 7/1

$323

Fri 7/1110:56 pmCLT - SNA

2 stops15h 15mMultiple Airlines

Sat 7/194:52 pmSNA - CLT

2 stops14h 10mMultiple Airlines

Deal found 7/1

$470

Fri 7/114:05 pmGSP - SNA

2 stops22h 21mMultiple Airlines

Sun 7/137:45 amSNA - GSP

3 stops22h 03mMultiple Airlines

Deal found 7/2

$627

Fri 7/117:00 amGSP - SNA

1 stop9h 46mAmerican Airlines

Sun 7/132:47 pmSNA - GSP

1 stop6h 32mAmerican Airlines

Deal found 7/2

$837

Sat 7/127:32 pmCLT - SNA

Nonstop4h 52mAmerican Airlines

Wed 7/1610:14 amSNA - CLT

1 stop9h 19mAmerican Airlines

Deal found 7/3

$519

Sat 7/123:48 pmCLT - SNA

1 stop7h 16mDelta

Wed 7/162:20 pmSNA - CLT

1 stop6h 38mDelta

Deal found 7/3

$529

Sun 7/133:26 pmCHS - SNA

2 stops23h 00mMultiple Airlines

Sat 8/96:45 amSNA - CHS

2 stops24h 00mMultiple Airlines

Deal found 7/3

$388

Sun 7/137:00 amCHS - SNA

1 stop6h 59mUnited Airlines

Sat 8/99:05 pmSNA - CHS

1 stop8h 42mUnited Airlines

Deal found 7/3

$566

One-way flights from South Carolina to Santa Ana
Search for one-way flight options from South Carolina to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

Tue 10/284:17 pmCLT - SNA

1 stop7h 36mUnited Airlines

Deal found 7/1

$51

Fri 8/221:08 pmCLT - SNA

2 stops11h 13mSpirit Airlines

Deal found 7/2

$84

Fri 10/245:34 pmCLT - SNA

1 stop23h 01mFrontier

Deal found 7/2

$90

Mon 9/2210:00 amSAV - SNA

2 stops15h 00mMultiple Airlines

Deal found 7/3

$120

Thu 8/712:11 pmMYR - SNA

2 stops26h 15mMultiple Airlines

Deal found 7/1

$127

Wed 8/204:49 pmSAV - SNA

2 stops29h 46mSpirit Airlines

Deal found 7/3

$133

Wed 9/242:59 pmCHS - SNA

1 stop7h 52mAmerican Airlines

Deal found 7/1

$160

Thu 8/74:22 pmMYR - SNA

1 stop6h 38mAmerican Airlines

Deal found 7/1

$176

Thu 9/47:15 amSAV - SNA

1 stop9h 38mAmerican Airlines

Deal found 7/3

$176

Sat 8/166:50 amSAV - SNA

1 stop7h 03mDelta

Deal found 7/1

$179

Thu 9/412:11 pmHHH - SNA

1 stop8h 02mDelta

Deal found 7/1

$206

Fri 8/2910:55 amSAV - SNA

2 stops9h 50mSouthwest

Deal found 7/1

$208

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Tue 7/29

5:00 pm-10:00 pm

1 stop8h 00m

Santa Ana J. Wayne/Orange Cnty

Tue 8/5

6:45 am-5:12 pm

1 stop7h 27m

$111

CharlotteSanta Ana

CLT - SNA

CLTSNA

Charlotte Douglas

Tue 7/29

9:21 am-7:03 pm

2 stops12h 42m

Santa Ana J. Wayne/Orange Cnty

Mon 8/4

7:58 pm-1:40 pm

1 stop14h 42m

$186

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sun 8/17

8:48 pm-11:29 am

1 stop17h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 8/23

8:30 pm-1:13 pm

2 stops13h 43m

$239

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Fri 8/15

10:38 am-11:29 am

1 stop27h 51m

Santa Ana J. Wayne/Orange Cnty

Fri 8/22

6:45 am-8:35 pm

2 stops10h 50m

$314

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 8/12

6:03 pm-10:15 am

1 stop19h 12m

Santa Ana J. Wayne/Orange Cnty

Tue 8/19

9:15 pm-5:17 pm

1 stop17h 02m

$318

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 7/30

3:25 pm-10:09 pm

1 stop9h 44m

Santa Ana J. Wayne/Orange Cnty

Wed 8/6

12:28 pm-10:02 pm

1 stop6h 34m

$319

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Tue 8/12

6:20 am-10:53 am

1 stop7h 33m

Santa Ana J. Wayne/Orange Cnty

Tue 8/19

7:12 pm-12:10 pm

2 stops13h 58m

$324

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 10/29

7:29 am-1:44 pm

1 stop9h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

12:44 pm-11:53 pm

1 stop8h 09m

$351

SavannahSanta Ana

SAV - SNA

SAVSNA

Savannah/Hilton Head

Wed 8/6

6:40 am-10:50 am

1 stop7h 10m

Santa Ana J. Wayne/Orange Cnty

Tue 8/12

2:00 pm-11:59 pm

1 stop6h 59m

$351

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Thu 9/4

5:20 pm-10:12 pm

1 stop7h 52m

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

12:13 pm-11:34 pm

1 stop8h 21m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 60 results

...

Best time to book a flight from South Carolina to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santa Ana

What is the cheapest month to book a flight from South Carolina to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Ana (average of $298). Flying from South Carolina to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SNA?

When flying from South Carolina to Santa Ana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santa Ana

Read through reviews of airlines operating flights from South Carolina to Santa Ana, such as Breeze Airways, Alaska Airlines, and Southwest. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Breeze Airways

8.1

Very good

183 reviews

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Alaska Airlines

8.0

Very good

10,000 reviews

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Southwest

8.0

Very good

4,266 reviews

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Delta

8.0

Very good

7,982 reviews

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

United Airlines

7.4

Good

8,861 reviews

Breeze Airways

8.1

Very good

183 reviews

Reviews

1 / 11

10.0

Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

What airport do you fly into for flights to Santa Ana from South Carolina?
Most people fly into Santa Ana J. Wayne/Orange Cnty (SNA) if they book a flight to Santa Ana from South Carolina. J. Wayne/Orange Cnty is conveniently located just 4.8 mi from Santa Ana’s city center.
What are the cheapest airlines to fly from South Carolina to Santa Ana one-way?
One-way options have recently been found by users for as low as $51 on United Airlines. Other airlines that offer cheap prices include Spirit Airlines from $84 and Frontier from $90 one-way.
What are the most popular routes from South Carolina to Santa Ana?
The most popular flight routes from South Carolina to Santa Ana are Charlotte Douglas - Santa Ana J. Wayne/Orange Cnty, Greenville - Santa Ana J. Wayne/Orange Cnty and Charleston - Santa Ana J. Wayne/Orange Cnty.
Can I find deals for flights from South Carolina to Santa Ana that include hotel bookings?
Yes. In addition to deals on South Carolina to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santa Ana.
Can I find deals for business class flights from South Carolina to Santa Ana?
Yes. Cheapflights offers flight deals from South Carolina to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Santa Ana?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Ana (average of $298). Flying from South Carolina to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Tustin

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from South Carolina to Santa Ana

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$270	Average$526	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$277	Average$494	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$296	Average$517	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$437	Average$526	FlexibilityNo cancel fee	On-time63%

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$51+ Cheap flights from South Carolina to Santa Ana (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Santa Ana

Keep the following information in mind while searching for South Carolina to Santa Ana flight deals. Data was last updated July 3, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from South Carolina to Santa Ana

Cheapest flights from South Carolina to Santa AnaExplore the most affordable flight options available from South Carolina to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from South Carolina to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santa Ana that are best for you.

Best time to book a flight from South Carolina to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santa Ana

What is the cheapest month to book a flight from South Carolina to Santa Ana?

What is the cheapest time of day to fly from SC to SNA?

Find hourly flight availability from South Carolina to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Reviews of airlines servicing Santa Ana

Read through reviews of airlines operating flights from South Carolina to Santa Ana, such as Breeze Airways, Alaska Airlines, and Southwest. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Ana from South Carolina?

What are the cheapest airlines to fly from South Carolina to Santa Ana one-way?

What are the most popular routes from South Carolina to Santa Ana?

Can I find deals for flights from South Carolina to Santa Ana that include hotel bookings?

How can I find direct flights from South Carolina to Santa Ana?

Can I find deals for business class flights from South Carolina to Santa Ana?

What is the cheapest month to book a flight from South Carolina to Santa Ana?

Traveling to a place near South Carolina?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South Carolina to Santa Ana

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Cheapest flights from South Carolina to Santa Ana
Explore the most affordable flight options available from South Carolina to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.