HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Ana

$89+ Cheap flights from South Carolina to Santa Ana, CA (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SNA
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Santa Ana

Cheapest flights from South Carolina to Santa Ana
Explore the most affordable flight options available from South Carolina to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:17 pmCLT - SNA
1 stop25h 51mFrontier
Thu 1/811:37 amSNA - CLT
1 stop27h 18mFrontier
Deal found 12/16$283
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:05 pmCHS - SNA
1 stop9h 25mUnited Airlines
Wed 12/316:45 amSNA - CHS
1 stop9h 33mUnited Airlines
Deal found 12/16$427
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amCLT - SNA
1 stop7h 54mDelta
Tue 12/3011:45 amSNA - CLT
1 stop7h 05mDelta
Deal found 12/17$436
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:39 pmCLT - SNA
Nonstop5h 12mAmerican Airlines
Thu 12/257:45 amSNA - CLT
Nonstop4h 43mAmerican Airlines
Deal found 12/17$437
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:39 pmCLT - SNA
Nonstop5h 12mAmerican Airlines
Tue 12/306:45 amSNA - CLT
1 stop7h 30mAmerican Airlines
Deal found 12/17$451
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amCLT - SNA
1 stop7h 54mDelta
Wed 12/317:00 amSNA - CLT
1 stop7h 02mDelta
Deal found 12/17$461
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:39 pmCLT - SNA
Nonstop5h 12mAmerican Airlines
Wed 12/317:45 amSNA - CLT
Nonstop4h 43mAmerican Airlines
Deal found 12/16$462
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:05 pmCHS - SNA
1 stop7h 41mUnited Airlines
Wed 12/316:45 amSNA - CHS
1 stop9h 33mUnited Airlines
Deal found 12/16$463
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amCLT - SNA
1 stop7h 54mDelta
Wed 12/316:45 amSNA - CLT
1 stop9h 25mDelta
Deal found 12/15$470
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amCLT - SNA
1 stop7h 54mDelta
Fri 12/2612:05 pmSNA - CLT
1 stop7h 06mDelta
Deal found 12/17$474
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:34 pmCLT - SNA
Nonstop5h 18mAmerican Airlines
Mon 12/297:45 amSNA - CLT
Nonstop4h 43mAmerican Airlines
Deal found 12/16$479
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:05 pmCHS - SNA
1 stop9h 25mUnited Airlines
Thu 1/16:45 amSNA - CHS
1 stop9h 33mUnited Airlines
Deal found 12/16$507

Find flight deals from South Carolina to Santa Ana

Keep the following information in mind while searching for South Carolina to Santa Ana flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$183
(CheapOair)

One-way from

$89
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$522
Provider with most accurate pricing for Myrtle Beach Intl-Los Angeles flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Los Angeles flights.
Search Deals
From South Carolina to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from South Carolina to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Santa Ana that are best for you.

Fly from

South Carolina

Fly to

Santa Ana

Route

Depart

Return

Price

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Fri 1/16

8:15 pm-8:57 pm

3 stops27h 42m

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

4:37 pm-7:20 pm

3 stops23h 43m

$331

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 1/7

2:15 pm-3:42 pm

3 stops28h 27m

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

4:37 pm-5:36 pm

3 stops21h 59m

$334

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 1/21

7:22 pm-10:27 pm

1 stop30h 05m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

5:00 pm-6:22 pm

1 stop22h 22m

$344

SavannahSanta Ana

SAV - SNA

SAVSNA

Savannah/Hilton Head

Sat 2/14

3:28 pm-9:45 pm

1 stop9h 17m

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

6:45 am-7:55 pm

1 stop10h 10m

$350

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 1/21

5:25 am-4:34 pm

2 stops14h 09m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

12:59 pm-11:55 pm

1 stop7h 56m

$351

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Wed 1/21

5:57 pm-10:56 pm

1 stop7h 59m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

7:00 am-7:02 pm

2 stops9h 02m

$354

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Mon 2/9

2:37 pm-10:56 pm

2 stops11h 19m

Santa Ana J. Wayne/Orange Cnty

Thu 2/12

11:41 am-10:52 pm

1 stop8h 11m

$376

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 1/10

1:53 pm-8:02 pm

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

7:00 am-5:04 pm

1 stop7h 04m

$377

Myrtle BeachSanta Ana

MYR - SNA

MYRSNA

Myrtle Beach Intl

Sat 1/10

1:13 pm-8:17 pm

1 stop10h 04m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

6:25 pm-12:41 pm

2 stops15h 16m

$382

CharlestonSanta Ana

CHS - SNA

CHSSNA

Charleston

Thu 2/26

6:32 pm-10:30 pm

1 stop30h 58m

Santa Ana J. Wayne/Orange Cnty

Sun 3/1

7:45 am-5:32 pm

1 stop30h 47m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santa Ana

What is the cheapest month to book a flight from South Carolina to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Santa Ana, California (average of $91). Flying from South Carolina to Santa Ana, California in January is currently the most expensive (average of $221). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SNA?

Find hourly flight availability from South Carolina to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

When flying from South Carolina to Santa Ana, California, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 36% versus a flight at noon.

What is the cheapest day to fly from South Carolina to Santa Ana, California?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Santa Ana. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Santa Ana, California flight should consider departing on Saturday afternoons when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Ana from South Carolina?

    Most people fly into Santa Ana J. Wayne/Orange Cnty (SNA) if they book a flight to Santa Ana from South Carolina. J. Wayne/Orange Cnty is conveniently located just 4.8 mi from Santa Ana’s city center.

  • How long is the flight from South Carolina to Santa Ana, California?

    Departing from South Carolina to Santa Ana, California will take you 9h 17m. The distance from South Carolina to Santa Ana, California is about 2117 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Santa Ana, California one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $160. Users have also found prices from $230 and $251 on Southwest and American Airlines, respectively.

  • What are the most popular routes from South Carolina to Santa Ana, California?

    The most popular flight routes from South Carolina to Santa Ana, California are Charlotte Douglas - Santa Ana J. Wayne/Orange Cnty, Charleston - Santa Ana J. Wayne/Orange Cnty and Greenville - Santa Ana J. Wayne/Orange Cnty.

  • Can I find deals for flights from South Carolina to Santa Ana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santa Ana.

  • Can I find deals for business class flights from South Carolina to Santa Ana?

    Yes. Cheapflights offers flight deals from South Carolina to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Santa Ana, California (average of $91). Flying from South Carolina to Santa Ana, California in January is currently the most expensive (average of $221). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Newark to Las Vegas flights
Newark to Los Angeles flights
Dallas/Fort Worth to Las Vegas flights
O'Hare Intl to Las Vegas flights
Seattle to Los Angeles flights
San Francisco to Las Vegas flights
Seattle to Las Vegas flights
John F Kennedy Intl to San Francisco flights
O'Hare Intl to Los Angeles flights
Atlanta to Las Vegas flights
Dulles Intl to Las Vegas flights
Dallas/Fort Worth to Los Angeles flights
LaGuardia to Los Angeles flights
Los Angeles to Las Vegas flights
LaGuardia to Las Vegas flights
Boston to Los Angeles flights
Los Angeles to San Francisco flights
Dulles Intl to Los Angeles flights
Denver to Las Vegas flights
Hobby to Las Vegas flights
Reagan-National to Los Angeles flights
Newark to San Francisco flights
Boston to Las Vegas flights
Baltimore to Los Angeles flights
Reagan-National to Las Vegas flights
Dallas/Fort Worth to San Francisco flights
Burbank to Las Vegas flights
Baltimore to Las Vegas flights
Santa Ana to Las Vegas flights
San Francisco to Los Angeles flights
Seattle to San Diego flights
Minneapolis to Las Vegas flights
O'Hare Intl to San Francisco flights
Detroit to Las Vegas flights
San Jose to Las Vegas flights
Orlando to Las Vegas flights
Atlanta to Los Angeles flights
Seattle to Ontario flights
Hobby to Los Angeles flights
Ontario to San Francisco flights
George Bush Intcntl to Las Vegas flights
Philadelphia to Las Vegas flights
San Jose to Los Angeles flights
San Francisco to Ontario flights
John F Kennedy Intl to San Diego flights
Austin to Las Vegas flights
Midway to Los Angeles flights
Denver to Los Angeles flights

Top 4 airlines flying from South Carolina to Santa Ana

Discover the top 4 airlines that operate flights from South Carolina to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$270Average$482FlexibilityNo cancel feeOn-time69%
DeltaCheapest$296Average$499FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$300Average$520FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$336Average$536FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.