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$224+ Cheap flights from Greenville to Santa Ana, CA (GSP - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SNA
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Greenville to Santa Ana

Cheapest flights from Greenville to Santa Ana
Explore the most affordable flight options available from Greenville to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:50 am
GSP
-
SNA
1 stop7h 37m
United Airlines
Tue 2/2410:51 am
SNA
-
GSP
1 stop6h 50m
United Airlines
Deal found 1/25$377
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:40 am
GSP
-
SNA
1 stop9h 09m
Delta
Tue 2/245:04 pm
SNA
-
GSP
2 stops13h 01m
Delta
Deal found 1/25$382
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:40 am
GSP
-
SNA
1 stop9h 09m
Delta
Mon 2/239:20 pm
SNA
-
GSP
1 stop8h 45m
Delta
Deal found 1/25$385
This Southwest deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/212:10 pm
GSP
-
SNA
2 stops11h 15m
Southwest
Tue 2/246:45 am
SNA
-
GSP
2 stops7h 55m
Southwest
Deal found 1/24$387
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:18 pm
GSP
-
SNA
1 stop8h 04m
Delta
Tue 2/245:04 pm
SNA
-
GSP
2 stops13h 01m
Delta
Deal found 1/25$390
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:18 pm
GSP
-
SNA
1 stop8h 04m
Delta
Thu 2/269:20 pm
SNA
-
GSP
1 stop8h 45m
Delta
Deal found 1/25$393
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
GSP
-
SNA
2 stops11h 33m
United Airlines
Tue 4/1410:50 am
SNA
-
GSP
1 stop6h 57m
United Airlines
Deal found 1/26$398
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:50 pm
GSP
-
SNA
2 stops9h 15m
Southwest
Tue 4/147:20 am
SNA
-
GSP
2 stops11h 20m
Southwest
Deal found 1/26$403
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:40 am
GSP
-
SNA
1 stop9h 09m
Delta
Fri 2/279:20 pm
SNA
-
GSP
1 stop8h 45m
Delta
Deal found 1/25$412
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:18 pm
GSP
-
SNA
1 stop8h 04m
Delta
Fri 2/279:20 pm
SNA
-
GSP
1 stop8h 45m
Delta
Deal found 1/25$420

Find flight deals from Greenville to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$377
(United Airlines)

One-way from

$224
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$506
Provider with most accurate pricing for Greenville-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Greenville to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Greenville to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Greenville to Santa Ana that are best for you.

Fly from

Greenville

Fly to

Santa Ana

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 2/21

6:50 am-11:27 am

1 stop7h 37m

Santa Ana J. Wayne/Orange Cnty

Tue 2/24

10:51 am-8:41 pm

1 stop6h 50m

$377

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 2/21

5:40 am-11:49 am

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Tue 2/24

5:04 pm-9:05 am

2 stops13h 01m

$382

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 2/21

5:40 am-11:49 am

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

9:20 pm-9:05 am

1 stop8h 45m

$385

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 2/21

5:40 am-11:49 am

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

9:20 pm-9:05 am

1 stop8h 45m

$385

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 4/7

12:50 pm-7:05 pm

2 stops9h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

7:20 am-9:40 pm

2 stops11h 20m

$403

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sat 2/21

5:40 am-11:49 am

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

7:10 pm-9:05 am

2 stops10h 55m

$417

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 2/24

5:40 am-4:14 pm

2 stops13h 34m

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

7:10 pm-9:05 am

2 stops10h 55m

$423

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 2/24

5:40 am-4:14 pm

2 stops13h 34m

Santa Ana J. Wayne/Orange Cnty

Wed 2/25

6:45 am-10:24 pm

2 stops12h 39m

$439

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sun 3/8

7:20 am-2:23 pm

1 stop10h 03m

$224

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Sun 3/8

5:32 pm-8:50 pm

3 stops30h 18m

$564

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from Greenville to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santa Ana in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santa Ana

How far ahead should I book a flight from Greenville to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Santa Ana. Price data was last updated on January 23, 2026.

The best time to book flights from Greenville to Santa Ana, California is 38 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Santa Ana, California?

Currently, March is the cheapest month in which you can book a flight from Greenville to Santa Ana, California (average of $96). Flying from Greenville to Santa Ana, California in December is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Santa Ana, California?

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated January 26, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Greenville to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santa Ana, California?

    Airlines like United Airlines and Delta fly from Greenville to Santa Ana, California in about 7h 37m. The time it takes to get you to your destination can typically vary by up to 1h 32m. The distance between Greenville and Santa Ana, California is about 2025 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Greenville to Santa Ana, California round-trip?

    Delta, at $296, was found to be the cheapest airline from Greenville to Santa Ana, California. An alternate airline flying to your destination would be American Airlines. Delta is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Greenville to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Greenville to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santa Ana.

  • Can I find deals for business class flights from Greenville to Santa Ana?

    Yes. Cheapflights offers flight deals from Greenville to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santa Ana, California?

    Currently, March is the cheapest month in which you can book a flight from Greenville to Santa Ana, California (average of $96). Flying from Greenville to Santa Ana, California in December is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Top 2 airlines flying from Greenville to Santa Ana

Discover the top 2 airlines that operate flights from Greenville to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$446FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$312Average$486FlexibilityNo cancel feeOn-time71%

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