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$274+ Cheap flights from Greenville to Santa Ana, CA (GSP - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SNA
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find cheap flights from Greenville to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Greenville to Santa Ana J. Wayne/Orange Cnty are usually found in September or August, booked 38 days in advance, depart on a Tuesday or Wednesday and return on a Saturday

Cheap flight deals from Greenville to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$352
(Mytrip)

One-way from

$274
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$446
Provider with most accurate pricing for Greenville-Santa Ana J. Wayne/Orange Cnty flight deals.
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Provider most trusted by Cheapflights users for Greenville-Santa Ana J. Wayne/Orange Cnty flights.
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From Greenville to Santa Ana J. Wayne/Orange Cnty
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One-way flight from Greenville to Santa Ana J. Wayne/Orange Cnty
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Highest demand for flights based on searches. 7% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Greenville to Santa Ana

Cheapest flights from Greenville to Santa Ana
Explore the most affordable flight options available from Greenville to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:00 pmGSP - SNA
3 stops31h 24mMultiple Airlines
Mon 12/88:19 pmSNA - GSP
3 stops17h 29mMultiple Airlines
Deal found 10/27$352
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amGSP - SNA
1 stop7h 51mAmerican Airlines
Wed 12/1712:38 pmSNA - GSP
1 stop8h 40mAmerican Airlines
Deal found 10/25$359
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:25 amGSP - SNA
2 stops13h 45mDelta
Wed 12/1712:45 pmSNA - GSP
1 stop7h 55mDelta
Deal found 10/27$364
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:40 amGSP - SNA
2 stops12h 28mDelta
Mon 12/1512:45 pmSNA - GSP
1 stop7h 55mDelta
Deal found 10/27$373
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:50 amGSP - SNA
1 stop7h 23mUnited Airlines
Sat 12/1310:40 amSNA - GSP
1 stop7h 09mUnited Airlines
Deal found 10/27$377
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:35 amGSP - SNA
2 stops13h 33mDelta
Thu 12/119:49 amSNA - GSP
2 stops10h 51mDelta
Deal found 10/27$378
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:35 amGSP - SNA
2 stops13h 33mDelta
Sat 12/138:00 amSNA - GSP
2 stops12h 41mDelta
Deal found 10/28$387
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:23 pmGSP - SNA
1 stop7h 13mDelta
Mon 12/159:20 pmSNA - GSP
1 stop8h 42mDelta
Deal found 10/27$399
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:17 pmGSP - SNA
1 stop8h 13mDelta
Thu 12/1112:45 pmSNA - GSP
1 stop6h 48mDelta
Deal found 10/27$403
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:08 amGSP - SNA
2 stops13h 10mDelta
Mon 12/1512:45 pmSNA - GSP
1 stop7h 55mDelta
Deal found 10/27$408

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Greenville to Santa Ana that are best for you.

Fly from

Greenville

Fly to

Santa Ana

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Fri 12/5

3:00 pm-7:24 pm

3 stops31h 24m

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

8:19 pm-4:48 pm

3 stops17h 29m

$352

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 12/9

6:00 am-11:48 am

1 stop8h 48m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

3:01 pm-12:18 am

1 stop6h 17m

$359

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 12/10

6:00 am-10:51 am

1 stop7h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

3:01 pm-12:18 am

1 stop6h 17m

$359

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Mon 12/8

5:35 am-2:15 pm

2 stops11h 40m

Santa Ana J. Wayne/Orange Cnty

Mon 12/15

9:20 pm-9:02 am

1 stop8h 42m

$364

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Tue 12/9

10:00 am-5:38 pm

2 stops10h 38m

Santa Ana J. Wayne/Orange Cnty

Tue 12/16

12:44 pm-11:59 pm

1 stop8h 15m

$364

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Thu 12/4

5:35 am-1:00 pm

2 stops10h 25m

Santa Ana J. Wayne/Orange Cnty

Mon 12/15

12:45 pm-11:40 pm

1 stop7h 55m

$364

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Wed 12/10

7:25 am-6:10 pm

2 stops13h 45m

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

12:45 pm-11:40 pm

1 stop7h 55m

$364

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Mon 11/10

6:12 am-10:42 am

1 stop7h 30m

$274

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

Mon 11/10

2:55 pm-10:13 pm

2 stops10h 18m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Compare providers for flights from Greenville to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santa Ana in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santa Ana

How far ahead should I book a flight from Greenville to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Santa Ana. Price data was last updated on October 24, 2025.

The best time to book flights from Greenville to Santa Ana, California is 38 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Santa Ana, California?

Currently, June is the cheapest month in which you can book a flight from Greenville to Santa Ana, California (average of $105). Flying from Greenville to Santa Ana, California in April is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Greenville to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santa Ana, California?

    Airlines like American Airlines and Delta fly from Greenville to Santa Ana, California in about 8h 48m. The time it takes to get you to your destination can typically vary by up to 2h 52m. The distance between Greenville and Santa Ana, California is about 2025 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Greenville to Santa Ana, California round-trip?

    Delta, at $296, was found to be the cheapest airline from Greenville to Santa Ana, California. An alternate airline flying to your destination would be American Airlines. Delta is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Greenville to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Greenville to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santa Ana.

  • Can I find deals for business class flights from Greenville to Santa Ana?

    Yes. Cheapflights offers flight deals from Greenville to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santa Ana, California?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Santa Ana, California (average of $105). Flying from Greenville to Santa Ana, California in April is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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Top 2 airlines flying from Greenville to Santa Ana

Discover the top 2 airlines that operate flights from Greenville to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$421FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$318Average$481FlexibilityNo cancel feeOn-time71%

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