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$223+ Cheap flights from Greenville to Santa Ana (GSP - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SNA
oct. 11 — oct. 181
sam. 10/11
sam. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Greenville to Santa Ana J. Wayne/Orange Cnty are usually found in November or October, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Saturday

Cheap flight deals from Greenville to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 11, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$223
(United Airlines)

Popular in

March

Cheapest in

November

Average price

$498
From Greenville to Santa Ana J. Wayne/Orange Cnty
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One-way flight from Greenville to Santa Ana J. Wayne/Orange Cnty
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Highest demand for flights based on searches. 5% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Greenville to Santa Ana

Cheapest flights from Greenville to Santa Ana
Explore the most affordable flight options available from Greenville to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 11/17:20 amGSP - SNA
1 stop9h 49mAmerican Airlines
mar. 11/43:03 pmSNA - GSP
1 stop6h 12mAmerican Airlines
Deal found 9/11$249
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/75:00 pmGSP - SNA
1 stop7h 40mUnited Airlines
mar. 10/149:05 pmSNA - GSP
1 stop8h 46mUnited Airlines
Deal found 9/9$297
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 11/110:30 amGSP - SNA
2 stops10h 35mSouthwest
mar. 11/47:25 pmSNA - GSP
2 stops11h 35mSouthwest
Deal found 9/11$306
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/1412:21 pmGSP - SNA
1 stop9h 25mUnited Airlines
sam. 10/186:45 amSNA - GSP
1 stop7h 08mUnited Airlines
Deal found 9/10$349
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/710:20 amGSP - SNA
2 stops9h 50mSouthwest
lun. 11/108:25 pmSNA - GSP
2 stops10h 35mSouthwest
Deal found 9/9$364
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/711:04 amGSP - SNA
2 stops14h 13mDelta
sam. 10/118:00 amSNA - GSP
2 stops12h 55mDelta
Deal found 9/9$378
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/76:00 amGSP - SNA
1 stop8h 37mAmerican Airlines
lun. 11/1012:27 pmSNA - GSP
1 stop8h 48mAmerican Airlines
Deal found 9/9$379
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/76:00 amGSP - SNA
2 stops10h 44mAmerican Airlines
sam. 10/1110:35 amSNA - GSP
1 stop9h 03mAmerican Airlines
Deal found 9/9$383
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/267:00 amGSP - SNA
1 stop7h 06mUnited Airlines
sam. 10/46:45 amSNA - GSP
1 stop7h 08mUnited Airlines
Deal found 9/9$398

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
Use the filters below to find and compare flights from Greenville to Santa Ana that are best for you.

Fly from

Greenville

Fly to

Santa Ana

Route

Depart

Return

Price

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

sam. 11/1

7:20 am-2:09 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

mar. 11/4

3:03 pm-12:15 am

1 stop6h 12m

$249

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

sam. 11/1

10:30 am-6:05 pm

2 stops10h 35m

Santa Ana J. Wayne/Orange Cnty

mar. 11/4

7:25 pm-10:00 am

2 stops11h 35m

$306

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

ven. 9/26

7:34 am-2:20 pm

1 stop9h 46m

Santa Ana J. Wayne/Orange Cnty

mar. 9/30

10:28 am-10:30 pm

1 stop9h 02m

$398

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

dim. 9/28

4:27 pm-10:12 pm

1 stop8h 45m

Santa Ana J. Wayne/Orange Cnty

sam. 10/4

12:13 pm-9:07 pm

1 stop5h 54m

$422

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

mer. 9/24

6:35 am-11:03 am

1 stop7h 28m

Santa Ana J. Wayne/Orange Cnty

sam. 10/4

8:00 am-11:34 pm

2 stops12h 34m

$427

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

sam. 9/27

6:35 am-3:56 pm

2 stops12h 21m

Santa Ana J. Wayne/Orange Cnty

sam. 10/4

11:30 am-11:34 pm

2 stops9h 04m

$432

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

sam. 9/27

7:35 am-11:03 am

1 stop6h 28m

Santa Ana J. Wayne/Orange Cnty

ven. 10/3

11:30 am-9:34 pm

1 stop7h 04m

$446

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

dim. 9/28

4:27 pm-10:12 pm

1 stop8h 45m

Santa Ana J. Wayne/Orange Cnty

lun. 10/6

9:20 pm-8:59 am

1 stop8h 39m

$446

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

ven. 9/26

5:30 am-11:03 am

1 stop8h 33m

Santa Ana J. Wayne/Orange Cnty

ven. 10/3

11:30 am-9:34 pm

1 stop7h 04m

$446

GreenvilleSanta Ana

GSP - SNA

GSPSNA

Greenville

sam. 9/27

7:35 am-11:03 am

1 stop6h 28m

Santa Ana J. Wayne/Orange Cnty

lun. 10/6

9:20 pm-8:59 am

1 stop8h 39m

$446

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 19 results
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Best time to book a flight from Greenville to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santa Ana

How far ahead should I book a flight from Greenville to Santa Ana?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Santa Ana. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Greenville to Santa Ana, you should look to book at least 38 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Greenville to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Greenville to Santa Ana (average of $298). Flying from Greenville to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated septembre 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santa Ana?

    For as low as $422, American Airlines can have you in Santa Ana from Greenville in 8h 45m. Airlines will cover a distance of 2025 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Greenville to Santa Ana round-trip?

    Currently priced at $296, Delta will fly you from Greenville to Santa Ana and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Southwest - these airlines can fly you to your destination from $321 and $391, respectively. Delta is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Greenville to Santa Ana one-way?

    $223 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $279 and $370, respectively.

  • Can I find deals for flights from Greenville to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Greenville to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santa Ana.

  • Can I find deals for business class flights from Greenville to Santa Ana?

    Yes. Cheapflights offers flight deals from Greenville to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Santa Ana (average of $298). Flying from Greenville to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Top 3 airlines flying from Greenville to Santa Ana

Discover the top 3 airlines that operate flights from Greenville to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$426FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$321Average$487FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$391Average$466FlexibilityNo cancel feeOn-time63%

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