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$390+ Cheap flights from Columbia, MO to Santa Ana (COU - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$421
(American Airlines)

One-way from

$390
(American Airlines)

Popular in

March

Cheapest in

June

Average price

$370
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
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One-way flight from Columbia Regional to Santa Ana J. Wayne/Orange Cnty
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Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/115:15 pmCOU - SNA
1 stop6h 54mAmerican Airlines
mar. 7/1510:19 amSNA - COU
1 stop8h 26mAmerican Airlines
Deal found 6/11$421

Cheapflights Fare Finder

Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Columbia

Fly to

Santa Ana

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

vie. 7/11

5:15 pm-10:09 pm

1 stop6h 54m

Santa Ana J. Wayne/Orange Cnty

mar. 7/15

10:19 am-8:45 pm

1 stop8h 26m

$421

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

mar. 7/1

4:40 pm-9:20 pm

1 stop6h 40m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Santa Ana

Rainfall in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

Temperature in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated junio 12, 2025.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Overall

7.2

Food

6.5

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Overall

7.2

Food

6.5

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Douglas,Sep 2023

RNO - LAX

There was a maintenance issue that caused us to depart over 1 hour late.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Columbia, Missouri to Santa Ana round-trip?

    Flying on American Airlines is currently your cheapest option to Santa Ana, with prices starting at $421.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Santa Ana (average of $298). Flying from Columbia, Missouri to Santa Ana in March is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Columbia?

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Tustin

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Top airline flying from Columbia to Santa Ana

Discover the top airline that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$418Average$529FlexibilityNo cancel feeOn-time71%

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