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$392+ Cheap flights from Columbia, MO to Santa Ana (COU - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$392
(American Airlines)
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
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Find flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/267:27 amCOU - SNA
1 stop8h 18mAmerican Airlines
Sat 8/306:45 amSNA - COU
1 stop7h 53mAmerican Airlines
Deal found 8/14$462
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:57 amCOU - SNA
1 stop6h 41mAmerican Airlines
Sat 12/1312:43 pmSNA - COU
1 stop7h 35mAmerican Airlines
Deal found 8/13$472
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:15 amCOU - SNA
1 stop6h 29mAmerican Airlines
Fri 8/2211:34 amSNA - COU
1 stop7h 59mAmerican Airlines
Deal found 8/14$540

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Columbia

Fly to

Santa Ana

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 10/25

7:10 am-2:01 pm

1 stop8h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 10/29

12:44 pm-10:40 pm

1 stop7h 56m

$392

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

7:20 am-11:32 am

1 stop6h 12m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

6:45 am-4:27 pm

1 stop7h 42m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated August 14, 2025.
See what other customers who have flown with American Airlines from Columbia to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Columbia, Missouri to Santa Ana round-trip?

    Flying on American Airlines is currently your cheapest option to Santa Ana, with prices starting at $418.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Santa Ana (average of $298). Flying from Columbia, Missouri to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Top airline flying from Columbia to Santa Ana

Discover the top airline that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$418Average$529FlexibilityNo cancel feeOn-time71%

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