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$472+ Cheap flights from Columbia, MO to Santa Ana (COU - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$472
(American Airlines)
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
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Find flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:09 pmCOU - SNA
1 stop5h 53mAmerican Airlines
Sat 12/1312:38 pmSNA - COU
1 stop7h 57mAmerican Airlines
Deal found 9/13$472
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/239:01 amCOU - SNA
1 stop26h 16mUnited Airlines
Mon 10/276:41 pmSNA - COU
1 stop24h 10mUnited Airlines
Deal found 9/13$525
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/241:49 pmCOU - SNA
1 stop9h 37mAmerican Airlines
Mon 10/2710:23 amSNA - COU
1 stop9h 08mAmerican Airlines
Deal found 9/13$530
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:01 amCOU - SNA
1 stop6h 47mAmerican Airlines
Sun 10/268:45 amSNA - COU
1 stop8h 34mAmerican Airlines
Deal found 9/13$604
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:01 amCOU - SNA
2 stops11h 08mAmerican Airlines
Mon 10/276:45 amSNA - COU
2 stops9h 58mAmerican Airlines
Deal found 9/13$660
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/279:00 amCOU - SNA
1 stop15h 19mUnited Airlines
Thu 10/308:50 amSNA - COU
1 stop10h 01mUnited Airlines
Deal found 9/15$693
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:00 amCOU - SNA
2 stops27h 17mUnited Airlines
Sun 10/266:41 pmSNA - COU
1 stop24h 10mUnited Airlines
Deal found 9/13$706

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Columbia

Fly to

Santa Ana

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 12/10

12:09 pm-4:02 pm

1 stop5h 53m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

12:38 pm-10:35 pm

1 stop7h 57m

$472

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 10/23

9:01 am-9:17 am

1 stop26h 16m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

6:41 pm-8:51 pm

1 stop24h 10m

$525

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 10/24

1:49 pm-9:26 pm

1 stop9h 37m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

10:23 am-9:31 pm

1 stop9h 08m

$530

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 10/24

8:00 am-9:17 am

2 stops27h 17m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

6:41 pm-8:51 pm

1 stop24h 10m

$561

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 10/24

1:49 pm-9:26 pm

1 stop9h 37m

Santa Ana J. Wayne/Orange Cnty

Sun 10/26

10:23 am-7:19 pm

1 stop6h 56m

$604

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 10/23

6:01 am-3:09 pm

2 stops11h 08m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

6:45 am-6:43 pm

2 stops9h 58m

$660

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated September 15, 2025.
See what other customers who have flown with American Airlines from Columbia to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to Santa Ana?

    Departing from Columbia, Missouri to Santa Ana will take you 5h 53m. The distance between Columbia, Missouri and Santa Ana is about 1466 mi.

  • What is the cheapest airline to fly from Columbia, Missouri to Santa Ana round-trip?

    Flying on American Airlines is currently your cheapest option to Santa Ana, with prices starting at $421.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Santa Ana (average of $298). Flying from Columbia, Missouri to Santa Ana in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Top airline flying from Columbia to Santa Ana

Discover the top airline that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$421Average$559FlexibilityNo cancel feeOn-time71%

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