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$299+ Cheap flights from Columbia, MO to Santa Ana, CA (COU - SNA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Find flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:05 pmCOU - SNA
1 stop9h 23mUnited Airlines
Sat 12/137:00 amSNA - COU
2 stops12h 22mUnited Airlines
Deal found 11/24$334
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:11 amCOU - SNA
1 stop6h 37mAmerican Airlines
Sat 12/133:01 pmSNA - COU
1 stop5h 34mAmerican Airlines
Deal found 11/24$502
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:05 pmCOU - SNA
1 stop6h 35mAmerican Airlines
Sun 12/287:45 amSNA - COU
1 stop7h 50mAmerican Airlines
Deal found 11/25$816
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:34 pmCOU - SNA
1 stop29h 56mUnited Airlines
Sat 1/36:45 amSNA - COU
1 stop11h 43mUnited Airlines
Deal found 11/24$837
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:45 amCOU - SNA
1 stop26h 53mUnited Airlines
Sun 1/46:40 pmSNA - COU
1 stop23h 48mUnited Airlines
Deal found 11/23$872
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/12:05 pmCOU - SNA
1 stop9h 34mAmerican Airlines
Wed 12/39:30 amSNA - COU
1 stop6h 13mAmerican Airlines
Deal found 11/24$876
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:05 amCOU - SNA
1 stop16h 25mUnited Airlines
Sun 1/46:40 pmSNA - COU
1 stop23h 48mUnited Airlines
Deal found 11/25$897
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:34 pmCOU - SNA
1 stop29h 56mUnited Airlines
Sun 1/47:05 pmSNA - COU
2 stops17h 30mUnited Airlines
Deal found 11/23$926

Cheap flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$299
(United Airlines)

Popular in

March

Cheapest in

January

Average price

$571
Provider with most accurate pricing for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($133 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Columbia

Fly to

Santa Ana

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 1/30

3:10 pm-10:24 pm

1 stop9h 14m

Santa Ana J. Wayne/Orange Cnty

Mon 2/2

6:25 pm-10:42 am

2 stops14h 17m

$299

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 12/9

3:05 pm-10:28 pm

1 stop9h 23m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

7:00 am-9:22 pm

2 stops12h 22m

$334

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Tue 1/27

11:17 am-6:41 pm

1 stop9h 24m

Santa Ana J. Wayne/Orange Cnty

Sat 1/31

1:17 pm-8:33 pm

1 stop5h 16m

$338

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 12/27

6:34 pm-10:30 pm

1 stop29h 56m

$657

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Compare providers for flights from Columbia to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Santa Ana in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated November 26, 2025.
See what other customers who have flown with American Airlines from Columbia to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to Santa Ana, California?

    There are many flights that can get you from Columbia, Missouri to Santa Ana, California in 9h 14m. Fly via United Airlines to get the fastest option. The distance from Columbia, Missouri to Santa Ana, California is about 1466 mi.

  • What is the cheapest airline to fly from Columbia, Missouri to Santa Ana, California round-trip?

    Our cheapest airline available from Columbia, Missouri to Santa Ana, California is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

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Top airline flying from Columbia to Santa Ana

Discover the top airline that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$392Average$566FlexibilityNo cancel feeOn-time71%

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