HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Ana

$316+ Cheap flights from Columbia, MO to Santa Ana, CA (COU - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SNA
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$408
(United Airlines)

One-way from

$316
(American Airlines)

Popular in

December

Cheapest in

January

Average price

$355
Provider with most accurate pricing for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Columbia Regional to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Columbia Regional to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($137 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease ($86 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from Columbia to Santa Ana

Cheapest flights from Columbia to Santa Ana
Explore the most affordable flight options available from Columbia to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This United Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:16 pmCOU - SNA
1 stop8h 34mUnited Airlines
Sat 8/298:40 amSNA - COU
2 stops10h 30mUnited Airlines
Deal found 1/10$334
This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/248:45 amCOU - SNA
1 stop6h 26mUnited Airlines
Wed 1/2811:05 amSNA - COU
1 stop7h 28mUnited Airlines
Deal found 1/9$408
This American Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 amCOU - SNA
1 stop6h 51mAmerican Airlines
Sun 3/87:45 amSNA - COU
1 stop7h 22mAmerican Airlines
Deal found 1/9$515
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2611:17 amCOU - SNA
1 stop9h 24mUnited Airlines
Fri 1/302:16 pmSNA - COU
1 stop22h 19mUnited Airlines
Deal found 1/11$548

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Columbia to Santa Ana that are best for you.

Fly from

Columbia

Fly to

Santa Ana

Route

Depart

Return

Price

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 1/24

8:45 am-1:11 pm

1 stop6h 26m

Santa Ana J. Wayne/Orange Cnty

Wed 1/28

11:05 am-8:33 pm

1 stop7h 28m

$408

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 3/6

6:00 am-10:51 am

1 stop6h 51m

Santa Ana J. Wayne/Orange Cnty

Sun 3/8

7:45 am-5:07 pm

1 stop7h 22m

$515

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Mon 1/26

11:17 am-6:41 pm

1 stop9h 24m

Santa Ana J. Wayne/Orange Cnty

Fri 1/30

2:16 pm-2:35 pm

1 stop22h 19m

$548

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 3/14

5:39 pm-10:45 pm

1 stop7h 06m

$316

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 3/12

12:27 pm-6:27 pm

1 stop8h 00m

$321

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 3/12

9:05 am-10:15 pm

1 stop15h 10m

$327

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 3/13

5:39 pm-10:45 pm

1 stop7h 06m

$349

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 3/13

11:15 am-10:15 pm

2 stops13h 00m

$360

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Thu 2/12

6:00 am-10:51 am

1 stop6h 51m

$380

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Fri 2/13

3:10 pm-9:27 pm

3 stops32h 17m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/11

Showing 1-10 of 11 results
1
2

Compare providers for flights from Columbia to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Santa Ana in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-Santa Ana, California flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Santa Ana

What is the cheapest month to book a flight from Columbia, Missouri to Santa Ana, California?

Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Santa Ana, California (average of $258). Flying from Columbia, Missouri to Santa Ana, California in March is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated January 12, 2026.
See what other customers who have flown with American Airlines from Columbia to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,111 reviews

Crew

8.0

Entertainment

6.9

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
11,111 reviews
American Airlines
7.2
Good
11,111 reviews

Crew

8.0

Entertainment

6.9

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to Santa Ana, California?

    There are many flights that can get you from Columbia, Missouri to Santa Ana, California in 6h 26m. Fly via United Airlines to get the fastest option. The distance from Columbia, Missouri to Santa Ana, California is about 1466 mi.

  • What is the cheapest airline to fly from Columbia, Missouri to Santa Ana, California round-trip?

    Our cheapest airline available from Columbia, Missouri to Santa Ana, California is American Airlines. Our recent data shows that you can find tickets from as low as $392 on this airline. You may be able to fly from Columbia, Missouri to Santa Ana, California for 35% less than the average price by searching for this airline.

  • Can I find deals for flights from Columbia to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Columbia to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Santa Ana.

  • Can I find deals for business class flights from Columbia to Santa Ana?

    Yes. Cheapflights offers flight deals from Columbia to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Santa Ana, California?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Santa Ana, California (average of $258). Flying from Columbia, Missouri to Santa Ana, California in March is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Las Vegas flights
Kansas City to Los Angeles flights
Kansas City to Las Vegas flights
St. Louis to Los Angeles flights
Kansas City to San Diego flights
Kansas City to San Francisco flights
St. Louis to San Diego flights
Kansas City to Ontario flights
St. Louis to San Francisco flights
Kansas City to Burbank flights
Kansas City to Santa Ana flights
St. Louis to Ontario flights
St. Louis to Sacramento flights
Kansas City to Sacramento flights
Springfield to Los Angeles flights
St. Louis to Santa Ana flights
Springfield to Las Vegas flights
St. Louis to Reno flights
St. Louis to Palm Springs flights
Kansas City to Palm Springs flights
St. Louis to Burbank flights
St. Louis to Medford flights
Springfield to Ontario flights
Kansas City to Oakland flights
Kansas City to San Jose flights
St. Louis to Long Beach flights
Kansas City to Reno flights
St. Louis to San Jose flights
Springfield to San Diego flights
St. Louis to Santa Barbara flights
Columbia to Las Vegas flights
Kansas City to Fresno flights
St. Louis to Fresno flights
Springfield to Sacramento flights
Kansas City to Long Beach flights
St. Louis to Oakland flights
Kansas City to Medford flights
Springfield to San Jose flights
Springfield to Burbank flights
Springfield to Reno flights
Joplin to Los Angeles flights
St. Louis to San Luis Obispo flights
Springfield to Santa Ana flights
Columbia to San Diego flights
St. Louis to Arcata flights
Columbia to San Francisco flights
Kansas City to Santa Barbara flights
St. Louis to Monterey flights
Springfield to Palm Springs flights
Joplin to Las Vegas flights

Top airline flying from Columbia to Santa Ana

Discover the top airline that operate flights from Columbia to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$392Average$566FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.