$350+ Cheap flights from Panama City (PTY) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
Aug 6 — Aug 131
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Francisco are usually found in September or April, booked 37 days in advance, depart on a Friday or Saturday and return on a Monday
Cheap flight deals from Panama City to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
This Trip.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 am
PTY
- SFO
3 stops29h 13m
Multiple Airlines
Wed 8/195:35 pm
SFO
- PTY
3 stops29h 00m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$635
This Trip.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:10 pm
PTY
- SFO
3 stops22h 24m
Multiple Airlines
Tue 9/15:35 pm
SFO
- PTY
3 stops37h 40m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$637
This Trip.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:10 pm
PTY
- SFO
3 stops45h 20m
Multiple Airlines
Sun 8/97:04 pm
SFO
- PTY
3 stops28h 51m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$645
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Wed 7/2911:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$685
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Thu 7/3011:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$686
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/2![Avianca logo]()
$691
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Fri 9/252:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 7/2![Avianca logo]()
$693
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Sat 8/222:30 am
SFO
- PTY
1 stop21h 25m
Avianca
Deal found 7/4![Avianca logo]()
$695
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Fri 9/411:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/2![Avianca logo]()
$703
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sat 7/2511:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$704
Best flights from Panama City to San FranciscoDiscover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/133:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Mon 7/2011:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/6![Avianca logo]()
$693
This Copa Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:39 pm
PTY
- SFO
Nonstop7h 21m
Copa Airlines
Mon 8/311:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Deal found 7/6![Copa Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:30 pm
PTY
- SFO
1 stop17h 52m
United Airlines
Thu 8/204:40 pm
SFO
- PTY
1 stop19h 34m
United Airlines
Deal found 7/3![United Airlines logo]()
$815
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/4![Avianca logo]()
$695
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Tue 7/282:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 7/6![Avianca logo]()
$704
This Copa Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:38 pm
PTY
- SFO
Nonstop7h 21m
Copa Airlines
Sun 8/238:21 pm
SFO
- PTY
Nonstop7h 14m
Copa Airlines
Deal found 7/4![Copa Airlines logo]()
$802
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:55 am
PTY
- SFO
1 stop25h 27m
United Airlines
Fri 8/74:40 pm
SFO
- PTY
1 stop23h 57m
United Airlines
Deal found 7/5![United Airlines logo]()
$815
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:53 pm
PTY
- SFO
Nonstop7h 47m
Copa Airlines
Tue 8/181:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:55 am
PTY
- SFO
1 stop25h 27m
United Airlines
Sun 8/95:00 am
SFO
- PTY
1 stop11h 37m
United Airlines
Deal found 7/3![United Airlines logo]()
$815
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:30 pm
PTY
- SFO
1 stop10h 35m
United Airlines
Wed 8/124:40 pm
SFO
- PTY
1 stop23h 57m
United Airlines
Deal found 7/6![United Airlines logo]()
$815
Last-minute flights from Panama City to San FranciscoDiscover last-minute flight deals from Panama City to San Francisco. Data last updated July 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Francisco. Data last updated July 7, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sat 7/2511:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$704
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Wed 7/2911:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$685
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Thu 7/3011:55 pm
SFO
- PTY
2 stops15h 05m
Avianca
Deal found 7/2![Avianca logo]()
$686
This Trip.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:10 pm
PTY
- SFO
3 stops45h 20m
Multiple Airlines
Sun 8/97:04 pm
SFO
- PTY
3 stops28h 51m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$645
This Trip.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 am
PTY
- SFO
3 stops29h 13m
Multiple Airlines
Wed 8/195:35 pm
SFO
- PTY
3 stops29h 00m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$635
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Sat 8/222:30 am
SFO
- PTY
1 stop21h 25m
Avianca
Deal found 7/4![Avianca logo]()
$695
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/2![Avianca logo]()
$691
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Fri 9/411:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 7/2![Avianca logo]()
$693
This Trip.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:10 pm
PTY
- SFO
3 stops22h 24m
Multiple Airlines
Tue 9/15:35 pm
SFO
- PTY
3 stops37h 40m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$637
One-way flights from Panama City to San FranciscoSearch for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:10 pm
PTY
- SFO
3 stops22h 17m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:10 pm
PTY
- SFO
3 stops29h 53m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:10 pm
PTY
- SFO
3 stops30h 08m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:10 pm
PTY
- SFO
3 stops43h 38m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:10 pm
PTY
- SFO
3 stops35h 13m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:30 am
PTY
- SFO
3 stops31h 00m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$363
This Super.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Deal found 7/2![Avianca logo]()
$374
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Deal found 7/2![Avianca logo]()
$377
This Kissandfly.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Deal found 7/5![Avianca logo]()
$379
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Deal found 7/6![Avianca logo]()
$388
Find flight deals from Panama City to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $637 (Trip.com) |
One-way from | $350 (Kiwi.com) |
Popular in | February |
Cheapest in | September |
Average price | $756 |
Good round-trip deal | $791 or less |
Good one-way deal | $1,810 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Mon 7/13
3:50 pm-6:25 am
2 stops16h 35m
San Francisco
Mon 7/20
11:55 pm-10:30 am
1 stop8h 35m
$693
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Thu 8/13
5:30 am-12:50 pm
1 stop9h 20m
San Francisco
Sun 8/23
11:55 pm-10:30 am
1 stop8h 35m
$695
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Thu 7/16
3:50 pm-11:55 pm
1 stop10h 05m
San Francisco
Tue 7/28
2:15 pm-1:55 am
1 stop9h 40m
$704
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Tue 8/25
12:39 pm-6:00 pm
Nonstop7h 21m
San Francisco
Mon 8/31
1:12 am-10:27 am
Nonstop7h 15m
$795
Quickest round-trip
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Thu 8/13
12:38 pm-5:59 pm
Nonstop7h 21m
San Francisco
Sun 8/23
8:21 pm-5:35 am
Nonstop7h 14m
$802
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Wed 8/12
5:53 pm-11:40 pm
Nonstop7h 47m
San Francisco
Tue 8/18
1:12 am-10:27 am
Nonstop7h 15m
$810
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Sat 8/1
3:30 pm-7:22 am
1 stop17h 52m
San Francisco
Thu 8/20
4:40 pm-2:14 pm
1 stop19h 34m
$815
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Sun 8/2
7:55 am-7:22 am
1 stop25h 27m
San Francisco
Fri 8/7
4:40 pm-6:37 pm
1 stop23h 57m
$815
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Sun 8/2
7:55 am-7:22 am
1 stop25h 27m
San Francisco
Sun 8/9
5:00 am-6:37 pm
1 stop11h 37m
$815
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Wed 8/5
3:30 pm-12:05 am
1 stop10h 35m
San Francisco
Wed 8/12
4:40 pm-6:37 pm
1 stop23h 57m
$815
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.
PTY-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
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Everything you need to know about your flight from Panama City to San Francisco
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How far ahead should I book a flight from Panama City to San Francisco?
The price you pay for your flight from Panama City to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Panama City to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Panama City to San Francisco (average of $609). Flying from Panama City to San Francisco in February is currently the most expensive (average of $793). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to SFO?
Find hourly flight availability from Panama City to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 7, 2026.
When flying from Panama City to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
The best insider tips for Panama City to San Francisco flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Panama City to San Francisco trip
Our travel experts
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 7, 2026.
Read through reviews of airlines operating flights from Panama City to San Francisco, such as Copa Airlines,United Airlines, andAvianca. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Crew
8.1
Boarding
7.8
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Overall
7.6
Entertainment
6.8
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Redwood City
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
Hayward
San Ramon
San Carlos
Daly City
Turlock
Vallejo
San Lorenzo
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Panama City and San Francisco flights
Browse other Panama City and San Francisco flight options. Last updated on July 7, 2026.
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Top 3 airlines flying from Panama City to San Francisco
Discover the top 3 airlines that operate flights from Panama City to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$153 | Average$565 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$742 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$539 | Average$733 | FlexibilityNo cancel fee | On-time69% |