San Francisco

$142+ Cheap flights from Maine to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SFO
May 3 — May 101
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Cheap flight deals from Maine to San Francisco

Cheapest flights from Maine to San Francisco
Explore the most affordable flight options available from Maine to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.

This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
BOS
-
SFO
1 stop14h 34m
Multiple Airlines
Wed 4/298:45 pm
SFO
-
BOS
Nonstop5h 42m
Multiple Airlines
Deal found 3/30$264
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:07 am
BOS
-
SFO
1 stop27h 34m
Multiple Airlines
Wed 5/273:10 pm
SFO
-
BOS
Nonstop5h 48m
Multiple Airlines
Deal found 3/30$266
This Priceline deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
BOS
-
SFO
1 stop14h 34m
Multiple Airlines
Fri 5/110:50 pm
SFO
-
BOS
1 stop8h 39m
Multiple Airlines
Deal found 3/31$267
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:01 pm
BOS
-
SFO
1 stop10h 33m
Multiple Airlines
Sat 5/239:00 pm
SFO
-
BOS
Nonstop5h 44m
Multiple Airlines
Deal found 3/31$269
This Frontier deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
BOS
-
SFO
1 stop14h 34m
Frontier
Sun 5/310:38 pm
SFO
-
BOS
1 stop9h 47m
Frontier
Deal found 3/29$270
This Cheapflightsfares deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:55 pm
BOS
-
SFO
Nonstop6h 36m
JetBlue
Wed 7/2910:17 pm
SFO
-
BOS
Nonstop5h 43m
JetBlue
Deal found 4/1$272
This Super.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:19 pm
BOS
-
SFO
Nonstop6h 40m
JetBlue
Sat 5/911:10 pm
SFO
-
BOS
Nonstop5h 45m
JetBlue
Deal found 4/2$273
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:01 pm
BOS
-
SFO
1 stop10h 33m
Multiple Airlines
Sun 5/108:44 pm
SFO
-
BOS
Nonstop5h 44m
Multiple Airlines
Deal found 3/31$274
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
BOS
-
SFO
1 stop16h 34m
Multiple Airlines
Sun 5/176:16 am
SFO
-
BOS
1 stop20h 28m
Multiple Airlines
Deal found 3/30$275
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
BOS
-
SFO
1 stop14h 34m
Frontier
Thu 4/3010:38 pm
SFO
-
BOS
1 stop10h 09m
Frontier
Deal found 3/31$276
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:40 am
BOS
-
SFO
Nonstop6h 49m
Delta
Sat 5/91:00 pm
SFO
-
BOS
Nonstop5h 50m
Delta
Deal found 4/1$277
This JetBlue deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:19 pm
BOS
-
SFO
Nonstop6h 40m
JetBlue
Sat 5/28:25 pm
SFO
-
BOS
Nonstop5h 42m
JetBlue
Deal found 4/2$278

Find flight deals from Maine to San Francisco

Keep the following information in mind while searching for Maine to San Francisco flight deals. Data was last updated April 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$264
(CheapOair)

One-way from

$142
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$432
Provider with most accurate pricing for Portland-San Francisco flight deals.
Provider most trusted by Cheapflights users for Portland-San Francisco flights.
From Maine to San Francisco
One-way flight from Maine to San Francisco
Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Maine to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSan Francisco

PWM - SFO

PWMSFO

Portland

Tue 8/18

5:45 am-2:40 pm

2 stops11h 55m

San Francisco

Tue 8/25

11:05 pm-2:15 pm

1 stop12h 10m

$302

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Thu 4/23

2:30 pm-11:20 pm

1 stop11h 50m

San Francisco

Wed 4/29

7:15 pm-8:05 am

2 stops9h 50m

$322

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Thu 4/23

1:09 pm-11:56 pm

1 stop13h 47m

San Francisco

Wed 4/29

2:00 pm-10:45 pm

Nonstop5h 45m

$329

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Wed 5/6

2:25 pm-11:15 pm

2 stops11h 50m

San Francisco

Mon 5/11

11:25 pm-12:15 pm

2 stops9h 50m

$332

PortlandSan Francisco

PWM - SFO

PWMSFO

Portland

Fri 5/22

6:25 pm-12:30 am

1 stop9h 05m

San Francisco

Wed 5/27

10:35 pm-10:07 am

1 stop8h 32m

$340

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Fri 5/15

8:25 pm-1:50 am

1 stop8h 25m

San Francisco

Sun 5/17

9:25 pm-6:27 am

Nonstop6h 02m

$353

PortlandSan Francisco

PWM - SFO

PWMSFO

Portland

Wed 4/29

6:33 pm-12:39 am

1 stop9h 06m

San Francisco

Wed 5/6

11:56 pm-10:23 am

1 stop7h 27m

$356

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Sat 5/2

7:00 am-2:21 pm

1 stop10h 21m

San Francisco

Tue 5/12

9:00 am-11:59 pm

1 stop11h 59m

$363

BostonSan Francisco

BOS - SFO

BOSSFO

Boston Logan Intl

Tue 5/5

2:25 pm-11:15 pm

2 stops11h 50m

San Francisco

Wed 5/13

5:40 am-6:35 pm

2 stops9h 55m

$369

PortlandSan Francisco

PWM - SFO

PWMSFO

Portland

Thu 5/7

12:55 pm-5:49 pm

1 stop7h 54m

San Francisco

Sat 5/16

11:25 am-11:09 pm

1 stop8h 44m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/29

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Maine to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to San Francisco

What is the cheapest month to book a flight from Maine to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Maine to San Francisco (average of $209). Flying from Maine to San Francisco in December is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Maine to San Francisco?

Related info for your journey

Find useful and relevant information for your journey from Maine to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from Maine?

    For a flight from Maine to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.0 mi from the center of the city.

  • How long is the flight from Maine to San Francisco?

    For as low as $311, Southwest can have you in San Francisco from Maine in 8h 24m. Airlines will cover a distance of 2715 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Maine to San Francisco one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $125. United Airlines flights start at $128 while deals on Delta start at $138 one-way.

  • What are the most popular routes from Maine to San Francisco?

  • Can I find deals for flights from Maine to San Francisco that include hotel bookings?

    Yes. In addition to deals on Maine to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to San Francisco.

  • Can I find deals for business class flights from Maine to San Francisco?

    Yes. Cheapflights offers flight deals from Maine to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Maine to San Francisco (average of $209). Flying from Maine to San Francisco in December is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Rancho Cordova
San Bruno
Watsonville
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Foster City

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Maine to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Maine to San Francisco

Discover the top 5 airlines that operate flights from Maine to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$236Average$358FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$243Average$467FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$543FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$272Average$498FlexibilityNo cancel feeOn-time63%
DeltaCheapest$276Average$407FlexibilityNo cancel feeOn-timeN/A

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