$122+ Cheap flights from Knoxville to San Francisco (TYS - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SFO
Aug 7 — Aug 141
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to San Francisco with Cheapflights
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Cheapest flights from Knoxville to San FranciscoExplore the most affordable flight options available from Knoxville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from Knoxville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Wed 8/126:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/3![Frontier logo]()
$244
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:46 pm
TYS
- SFO
1 stop8h 19m
American Airlines
Mon 8/2411:40 pm
SFO
- TYS
1 stop9h 04m
American Airlines
Deal found 7/7![American Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:20 pm
TYS
- SFO
1 stop8h 33m
Delta
Sat 10/1011:45 pm
SFO
- TYS
1 stop8h 16m
Delta
Deal found 7/7![Delta logo]()
$257
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- SFO
1 stop7h 04m
Frontier
Tue 8/1112:38 pm
SFO
- TYS
1 stop27h 46m
Frontier
Deal found 7/4![Frontier logo]()
$271
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:55 pm
TYS
- SFO
2 stops10h 15m
Southwest
Mon 8/246:20 am
SFO
- TYS
1 stop6h 35m
Southwest
Deal found 7/6![Southwest logo]()
$278
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Mon 8/176:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/3![Frontier logo]()
$279
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
TYS
- SFO
2 stops9h 15m
Southwest
Mon 8/2411:40 pm
SFO
- TYS
2 stops9h 25m
Southwest
Deal found 7/7![Southwest logo]()
$283
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:45 pm
TYS
- SFO
1 stop9h 12m
Delta
Fri 10/211:35 pm
SFO
- TYS
1 stop8h 09m
Delta
Deal found 7/8![Delta logo]()
$286
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:50 pm
TYS
- SFO
1 stop9h 00m
Southwest
Mon 9/2111:40 pm
SFO
- TYS
2 stops9h 25m
Southwest
Deal found 7/7![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:15 am
TYS
- SFO
1 stop9h 13m
American Airlines
Tue 8/186:30 am
SFO
- TYS
1 stop8h 04m
American Airlines
Deal found 7/7![American Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
TYS
- SFO
1 stop7h 30m
United Airlines
Fri 10/211:10 pm
SFO
- TYS
1 stop8h 27m
United Airlines
Deal found 7/7![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:20 pm
TYS
- SFO
1 stop9h 00m
Southwest
Fri 10/239:35 am
SFO
- TYS
1 stop6h 15m
Southwest
Deal found 7/7![Southwest logo]()
$313
Best flights from Knoxville to San FranciscoDiscover carefully curated flight deals from Knoxville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from Knoxville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:15 am
TYS
- SFO
1 stop10h 12m
Delta
Sat 8/1510:00 pm
SFO
- TYS
1 stop8h 44m
Delta
Deal found 7/7![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am
TYS
- SFO
2 stops8h 35m
Southwest
Wed 9/1611:40 pm
SFO
- TYS
2 stops9h 40m
Southwest
Deal found 7/4![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:00 am
TYS
- SFO
2 stops8h 35m
Southwest
Wed 8/125:40 am
SFO
- TYS
2 stops10h 15m
Southwest
Deal found 7/3![Southwest logo]()
$411
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:25 pm
TYS
- SFO
1 stop8h 22m
Delta
Sat 9/510:00 pm
SFO
- TYS
1 stop8h 44m
Delta
Deal found 7/3![Delta logo]()
$418
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:55 am
TYS
- SFO
1 stop8h 55m
Southwest
Sun 11/156:50 am
SFO
- TYS
2 stops10h 40m
Southwest
Deal found 7/3![Southwest logo]()
$423
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:55 pm
TYS
- SFO
2 stops10h 46m
Delta
Sun 11/1511:45 pm
SFO
- TYS
1 stop8h 21m
Delta
Deal found 7/7![Delta logo]()
$433
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:13 pm
TYS
- SFO
1 stop8h 44m
Delta
Mon 10/510:00 pm
SFO
- TYS
1 stop8h 40m
Delta
Deal found 7/4![Delta logo]()
$441
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am
TYS
- SFO
2 stops8h 50m
Southwest
Mon 12/215:20 am
SFO
- TYS
2 stops10h 20m
Southwest
Deal found 7/6![Southwest logo]()
$450
Last-minute flights from Knoxville to San FranciscoDiscover last-minute flight deals from Knoxville to San Francisco. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Francisco. Data last updated July 8, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- SFO
1 stop7h 04m
Frontier
Tue 8/1112:38 pm
SFO
- TYS
1 stop27h 46m
Frontier
Deal found 7/4![Frontier logo]()
$271
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:38 am
TYS
- SFO
1 stop9h 35m
Delta
Tue 8/1111:35 am
SFO
- TYS
1 stop6h 59m
Delta
Deal found 7/7![Delta logo]()
$257
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Wed 8/126:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/3![Frontier logo]()
$244
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Fri 8/76:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/4![Frontier logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:19 pm
TYS
- SFO
2 stops24h 59m
Multiple Airlines
Wed 8/127:08 pm
SFO
- TYS
1 stop25h 29m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:15 am
TYS
- SFO
1 stop9h 13m
American Airlines
Tue 8/186:30 am
SFO
- TYS
1 stop8h 04m
American Airlines
Deal found 7/7![American Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- SFO
2 stops8h 35m
Southwest
Tue 8/1811:05 pm
SFO
- TYS
1 stop10h 00m
Southwest
Deal found 7/7![Southwest logo]()
$327
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Mon 8/176:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/3![Frontier logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:46 pm
TYS
- SFO
1 stop8h 19m
American Airlines
Mon 8/2411:40 pm
SFO
- TYS
1 stop9h 04m
American Airlines
Deal found 7/7![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
TYS
- SFO
2 stops9h 15m
Southwest
Mon 8/2411:40 pm
SFO
- TYS
2 stops9h 25m
Southwest
Deal found 7/7![Southwest logo]()
$283
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:55 pm
TYS
- SFO
2 stops10h 15m
Southwest
Mon 8/246:20 am
SFO
- TYS
1 stop6h 35m
Southwest
Deal found 7/6![Southwest logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- SFO
1 stop28h 17m
Multiple Airlines
Sun 8/3010:35 pm
SFO
- TYS
2 stops16h 30m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$328
One-way flights from Knoxville to San FranciscoSearch for one-way flight options from Knoxville to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from Knoxville to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Deal found 7/4![Frontier logo]()
$122
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:50 pm
TYS
- SFO
1 stop9h 00m
Southwest
Deal found 7/7![Southwest logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:51 pm
TYS
- SFO
2 stops33h 41m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:47 pm
TYS
- SFO
1 stop22h 38m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$146
This Priceline deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Deal found 7/5![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:49 pm
TYS
- SFO
2 stops32h 07m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:47 pm
TYS
- SFO
2 stops33h 31m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:00 am
TYS
- SFO
2 stops38h 18m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$166
Find flight deals from Knoxville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $244 (Expedia) |
One-way from | $122 (Frontier) |
Popular in | June |
Cheapest in | February |
Average price | $498 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Knoxville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 8/5
7:15 am-2:27 pm
1 stop10h 12m
San Francisco
Sat 8/15
10:00 pm-9:44 am
1 stop8h 44m
$378
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 9/9
7:00 am-12:35 pm
2 stops8h 35m
San Francisco
Wed 9/16
11:40 pm-12:20 pm
2 stops9h 40m
$393
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 8/5
7:00 am-12:35 pm
2 stops8h 35m
San Francisco
Wed 8/12
5:40 am-6:55 pm
2 stops10h 15m
$411
Quickest round-trip
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Fri 8/28
6:25 pm-11:47 pm
1 stop8h 22m
San Francisco
Sat 9/5
10:00 pm-9:44 am
1 stop8h 44m
$418
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 11/11
7:55 am-1:50 pm
1 stop8h 55m
San Francisco
Sun 11/15
6:50 am-8:30 pm
2 stops10h 40m
$423
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Thu 11/12
3:55 pm-11:41 pm
2 stops10h 46m
San Francisco
Sun 11/15
11:45 pm-11:06 am
1 stop8h 21m
$433
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Tue 9/29
6:13 pm-11:57 pm
1 stop8h 44m
San Francisco
Mon 10/5
10:00 pm-9:40 am
1 stop8h 40m
$441
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 12/16
7:00 am-12:50 pm
2 stops8h 50m
San Francisco
Mon 12/21
5:20 am-6:40 pm
2 stops10h 20m
$450
Cheapest one-way
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Wed 10/14
8:20 am-2:35 pm
1 stop9h 15m
$125
Quickest one-way
KnoxvilleSan Francisco
TYS - SFO
TYSSFO
Knoxville McGhee Tyson
Mon 8/31
5:45 pm-9:55 pm
1 stop7h 10m
$147
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Francisco in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Knoxville with our price prediction graph.
TYS-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Francisco
How far ahead should I book a flight from Knoxville to San Francisco?
The best time to book flights from Knoxville to San Francisco is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Knoxville to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Knoxville to San Francisco (average of $329). Flying from Knoxville to San Francisco in June is currently the most expensive (average of $702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 8, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
6.0
GoodJames,Aug 2023
SEA - SFO
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Redwood City
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
Hayward
San Ramon
San Carlos
Turlock
Vallejo
San Lorenzo
Davis
Browse thousands of different options on Cheapflights for your next trip
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Knoxville and San Francisco flights
Browse other Knoxville and San Francisco flight options. Last updated on July 8, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on July 8, 2026.
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Other flights to San Francisco
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Top 4 airlines flying from Knoxville to San Francisco
Discover the top 4 airlines that operate flights from Knoxville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$157 | Average$254 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$308 | Average$468 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$468 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$500 | FlexibilityNo cancel fee | On-time69% |