What is the cheapest airline to fly from Greenville, North Carolina to San Francisco round-trip?

Currently priced at $417, American Airlines will fly you from Greenville, North Carolina to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

What is the cheapest day to fly from Greenville, North Carolina to San Francisco?

Travelers seeking maximum savings on their Greenville, North Carolina to San Francisco flight should consider departing on Saturday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What is the cheapest day to fly round-trip from Greenville, North Carolina to San Francisco?

Users have found that leaving on a Friday can be a cost-effective option. It’s possible to save up to 60% on your flight compared to booking on days when demand is much higher.

What is the cheapest time of day to fly from PGV to SFO?

It’s optimal to fly from Greenville, North Carolina to San Francisco at noon. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the morning.

Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Greenville to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

Can I find deals for business class flights from Greenville to San Francisco?

Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$417+ Flights from Greenville, NC to San Francisco

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Cheap flight deals from Greenville to San Francisco

Round-trip from	$417 (American Airlines)

From Pitt-Greenville to San Francisco

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Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Fri 9/1912:51 pmPGV - SFO

1 stop8h 45mAmerican Airlines

Sat 10/412:38 pmSFO - PGV

1 stop7h 48mAmerican Airlines

Deal found 6/30

$417

Best flights from Greenville to San Francisco
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 30, 2025.

Fri 9/1912:51 pmPGV - SFO

1 stop8h 45mAmerican Airlines

Sat 10/412:38 pmSFO - PGV

1 stop7h 48mAmerican Airlines

Deal found 6/30

$417

Last-minute flights from Greenville to San Francisco
Discover last-minute flight deals from Greenville to San Francisco. Data last updated June 30, 2025 and is based on user searches.

Tue 7/155:10 amPGV - SFO

1 stop10h 04mAmerican Airlines

Sat 7/191:16 pmSFO - PGV

1 stop7h 41mAmerican Airlines

Deal found 6/30

$517

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Francisco

PGV - SFO

PGVSFO

Pitt-Greenville

Fri 9/19

12:51 pm-6:36 pm

1 stop8h 45m

San Francisco

Sat 10/4

12:38 pm-11:26 pm

1 stop7h 48m

$417

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $276). Flying from Greenville, North Carolina to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with American Airlines from Greenville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

8.0

Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

8.0

Excellent

Aaron,Sep 2023

CLT - ORD

The extra cost of first class was not worth it.

Related info for your journey

What is the cheapest airline to fly from Greenville, North Carolina to San Francisco round-trip?
Currently priced at $417, American Airlines will fly you from Greenville, North Carolina to San Francisco and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.
Can I find deals for flights from Greenville to San Francisco that include hotel bookings?
Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Greenville to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.
Can I find deals for business class flights from Greenville to San Francisco?
Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Greenville, North Carolina to San Francisco (average of $276). Flying from Greenville, North Carolina to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Foster City

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Top airline flying from Greenville to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$248	Average$418	FlexibilityNo cancel fee	On-time71%

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$417+ Cheap flights from Greenville, NC to San Francisco (PGV - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Greenville to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Greenville to San Francisco

Round-trip from

Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with American Airlines from Greenville to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Greenville, North Carolina to San Francisco round-trip?

Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

How can I find direct flights from Greenville to San Francisco?

Can I find deals for business class flights from Greenville to San Francisco?

What is the cheapest month to book a flight from Greenville, North Carolina to San Francisco?

Traveling to a place near Greenville?

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Alternative routes for Greenville to San Francisco

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Top airline flying from Greenville to San Francisco

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Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.