HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco Bay Area

$124+ Cheap flights from Des Moines (DSM) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SFO
dic. 19 — dic. 261
vie. 12/19
vie. 12/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to San Francisco Bay Area with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Des Moines to San Francisco Bay Area

Cheapest flights from Des Moines to San Francisco Bay Area
Explore the most affordable flight options available from Des Moines to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:28 pmDSM - SFO
1 stop14h 20mMultiple Airlines
lun. 12/156:30 amSFO - DSM
1 stop10h 33mMultiple Airlines
Deal found 11/19$216
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/57:58 pmDSM - SFO
1 stop6h 26mFrontier
jue. 12/116:00 amSFO - DSM
2 stops35h 03mFrontier
Deal found 11/18$229
This CheapOair deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:58 pmDSM - SFO
1 stop6h 26mFrontier
lun. 12/156:30 amSFO - DSM
1 stop10h 33mFrontier
Deal found 11/19$230
This Frontier deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/87:58 pmDSM - SFO
1 stop6h 26mFrontier
vie. 12/126:30 amSFO - DSM
1 stop10h 33mFrontier
Deal found 11/17$242
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:58 pmDSM - SFO
2 stops51h 13mFrontier
jue. 12/254:07 pmSFO - DSM
1 stop25h 37mFrontier
Deal found 11/16$250
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/57:58 pmDSM - SFO
1 stop6h 26mMultiple Airlines
jue. 12/116:00 amSFO - DSM
1 stop7h 31mMultiple Airlines
Deal found 11/18$258
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/47:00 amDSM - SFO
1 stop10h 17mMultiple Airlines
lun. 12/88:48 amSFO - DSM
1 stop8h 15mMultiple Airlines
Deal found 11/19$277
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:58 pmDSM - SFO
1 stop6h 26mFrontier
vie. 12/2610:44 pmSFO - DSM
2 stops19h 00mFrontier
Deal found 11/16$280
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/133:38 pmDSM - SJC
1 stop6h 50mAmerican Airlines
mié. 1/76:00 amSJC - DSM
1 stop5h 48mAmerican Airlines
Deal found 11/18$317
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:00 amDSM - SJC
2 stops38h 13mMultiple Airlines
jue. 12/183:27 pmSJC - DSM
1 stop25h 37mMultiple Airlines
Deal found 11/18$356
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:20 pmDSM - SJC
1 stop5h 57mAmerican Airlines
jue. 12/186:00 amSJC - DSM
1 stop9h 09mAmerican Airlines
Deal found 11/19$393
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:05 pmDSM - OAK
1 stop5h 40mSouthwest
mié. 12/1012:35 pmOAK - DSM
1 stop5h 20mSouthwest
Deal found 11/19$412

Cheap flight deals from Des Moines to San Francisco Bay Area

Keep the following information in mind while searching for Des Moines to San Francisco Bay Area flight deals. Data was last updated noviembre 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$216
(Kiwi.com)

One-way from

$124
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$481
Provider with most accurate pricing for Des Moines-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-San Francisco flights.
Search Deals
From Des Moines to San Francisco Bay Area
Search Deals
One-way flight from Des Moines to San Francisco Bay Area
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 19, 2025.
Use the filters below to find and compare flights from Des Moines to San Francisco Bay Area that are best for you.

Fly from

Des Moines

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

vie. 1/9

8:17 pm-8:47 pm

1 stop26h 30m

San Francisco

dom. 1/11

11:35 pm-7:22 pm

2 stops17h 47m

$292

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

mar. 1/13

4:21 pm-9:28 pm

1 stop7h 07m

San Jose

mié. 1/14

6:20 am-3:41 pm

1 stop7h 21m

$317

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

jue. 1/22

2:34 pm-6:43 pm

1 stop6h 09m

San Jose

mar. 1/27

6:00 am-1:48 pm

1 stop5h 48m

$355

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

jue. 1/15

5:35 am-12:56 pm

1 stop9h 21m

San Jose

mar. 1/20

10:45 pm-10:38 am

1 stop9h 53m

$355

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

jue. 1/22

5:35 am-12:56 pm

1 stop9h 21m

San Jose

mar. 1/27

9:46 am-9:24 pm

2 stops9h 38m

$360

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

vie. 1/2

8:29 pm-8:23 am

1 stop13h 54m

San Francisco

vie. 1/9

8:58 am-7:22 pm

1 stop8h 24m

$369

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

mar. 1/6

6:54 am-1:47 pm

1 stop8h 53m

San Francisco

vie. 1/9

12:40 am-10:19 am

1 stop7h 39m

$372

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

mié. 2/11

8:35 am-2:20 pm

2 stops7h 45m

San Francisco

mar. 2/17

9:10 am-9:20 pm

2 stops10h 10m

$373

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

jue. 1/15

3:04 pm-11:59 pm

1 stop10h 55m

San Francisco

dom. 1/18

1:19 pm-10:30 pm

1 stop7h 11m

$376

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

jue. 1/15

5:21 am-10:57 am

1 stop7h 36m

San Jose

dom. 1/18

2:18 pm-11:58 pm

1 stop7h 40m

$376

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 47 results
1
2
3
...
5

Best time to book a flight from Des Moines to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to San Francisco Bay Area

What is the cheapest month to book a flight from Des Moines to San Francisco Bay Area?

Currently, December is the cheapest month in which you can book a flight from Des Moines to San Francisco Bay Area (average of $144). Flying from Des Moines to San Francisco Bay Area in November is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to XIH?

Find hourly flight availability from Des Moines to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 19, 2025.

When flying from Des Moines to San Francisco Bay Area, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 51% versus a flight in the morning.

What is the cheapest day to fly from Des Moines to San Francisco Bay Area?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to San Francisco Bay Area. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to San Francisco Bay Area flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated noviembre 19, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to San Francisco Bay Area. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,249 reviews
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,004 reviews
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,025 reviews
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,046 reviews
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,106 reviews
Southwest
8.0
Very good
4,249 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to San Francisco Bay Area?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to San Francisco Bay Area. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • How long is the flight from Des Moines to San Francisco Bay Area?

    Airlines like Frontier, Delta, and Southwest fly from Des Moines to San Francisco Bay Area in about 7h 07m. The time it takes to get you to your destination can typically vary by up to 19h 23m. The distance from Des Moines to San Francisco Bay Area is about 1527 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to San Francisco Bay Area one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $132. Delta flights start at $159 while deals on American Airlines start at $197 one-way.

  • What are the most popular routes from Des Moines to San Francisco Bay Area?

    Most travelers choose Des Moines - San Francisco, Des Moines - San Jose or Des Moines - Oakland when deciding on the best route from Des Moines to San Francisco Bay Area.

  • Can I find deals for flights from Des Moines to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Francisco Bay Area.

  • Can I find deals for business class flights from Des Moines to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Des Moines to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to San Francisco Bay Area?

    Currently, December is the cheapest month in which you can book a flight from Des Moines to San Francisco Bay Area (average of $144). Flying from Des Moines to San Francisco Bay Area in November is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to San Francisco Bay Area

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Las Vegas flights
Omaha to Las Vegas flights
Omaha to Los Angeles flights
Cedar Rapids to Las Vegas flights
Des Moines to Los Angeles flights
Cedar Rapids to San Diego flights
Omaha to San Francisco flights
Omaha to San Diego flights
Des Moines to San Diego flights
Cedar Rapids to Los Angeles flights
Des Moines to San Francisco flights
Cedar Rapids to San Francisco flights
Moline to Las Vegas flights
Cedar Rapids to Ontario flights
Moline to Los Angeles flights
Des Moines to Ontario flights
Omaha to Ontario flights
Des Moines to Sacramento flights
Omaha to Palm Springs flights
Des Moines to San Jose flights
Cedar Rapids to Santa Ana flights
Omaha to Santa Ana flights
Cedar Rapids to San Jose flights
Moline to Santa Ana flights
Des Moines to Palm Springs flights
Des Moines to Reno flights
Moline to San Diego flights
Moline to Ontario flights
Omaha to Burbank flights
Omaha to Sacramento flights
Cedar Rapids to Palm Springs flights
Omaha to San Jose flights
Omaha to Monterey flights
Des Moines to Santa Barbara flights
Cedar Rapids to Reno flights
Omaha to Oakland flights
Cedar Rapids to Long Beach flights
Des Moines to Santa Ana flights
Omaha to Reno flights
Cedar Rapids to Sacramento flights
Des Moines to San Luis Obispo flights
Moline to San Francisco flights
Moline to Palm Springs flights
Omaha to Fresno flights
Omaha to Long Beach flights
Des Moines to Oakland flights
Des Moines to Long Beach flights
Omaha to Santa Barbara flights
Cedar Rapids to Burbank flights
La Crosse to Las Vegas flights

Top 5 airlines flying from Des Moines to San Francisco Bay Area

Discover the top 5 airlines that operate flights from Des Moines to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$144Average$252FlexibilityNo cancel feeOn-time62%
DeltaCheapest$265Average$371FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$296Average$512FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$296Average$579FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$344Average$474FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.