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San Francisco Bay Area

$130+ Cheap flights from Des Moines (DSM) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SFO
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to San Francisco Bay Area

Keep the following information in mind while searching for Des Moines to San Francisco Bay Area flight deals. Data was last updated junio 12, 2025.

Round-trip from

$257
(Mytrip)

One-way from

$130
(Frontier)

Popular in

March

Cheapest in

September

Average price

$438
From Des Moines to San Francisco Bay Area
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One-way flight from Des Moines to San Francisco Bay Area
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Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to San Francisco Bay Area

Cheapest flights from Des Moines to San Francisco Bay Area
Explore the most affordable flight options available from Des Moines to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/307:30 amDSM - OAK
1 stop18h 03mMultiple Airlines
lun. 8/116:00 amOAK - DSM
2 stops14h 38mMultiple Airlines
Deal found 6/12$257
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/147:33 pmDSM - SFO
1 stop6h 46mFrontier
vie. 7/186:37 amSFO - DSM
1 stop10h 11mFrontier
Deal found 6/9$260
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/52:21 pmDSM - SJC
2 stops35h 33mMultiple Airlines
dom. 8/106:30 amSJC - DSM
1 stop28h 05mMultiple Airlines
Deal found 6/11$279
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/12:20 pmDSM - SJC
1 stop10h 35mDelta
sáb. 7/56:35 amSJC - DSM
1 stop9h 27mDelta
Deal found 6/12$297
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/46:09 pmDSM - SFO
1 stop7h 00mAmerican Airlines
mar. 9/912:47 amSFO - DSM
1 stop6h 52mAmerican Airlines
Deal found 6/11$297
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/165:44 amDSM - SFO
1 stop10h 40mDelta
mar. 8/1912:35 amSFO - DSM
1 stop7h 43mDelta
Deal found 6/12$306
This WAYA deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/237:30 amDSM - SFO
1 stop6h 45mMultiple Airlines
lun. 7/2810:37 amSFO - DSM
1 stop9h 58mMultiple Airlines
Deal found 6/11$316
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/912:15 pmDSM - SFO
2 stops9h 35mSouthwest
sáb. 9/136:50 amSFO - DSM
2 stops11h 30mSouthwest
Deal found 6/10$325
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/166:35 amDSM - SJC
1 stop7h 20mSouthwest
mié. 10/226:55 amSJC - DSM
1 stop5h 20mSouthwest
Deal found 6/10$348
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/11:45 pmDSM - OAK
1 stop7h 30mSouthwest
sáb. 7/55:10 amOAK - DSM
1 stop5h 00mSouthwest
Deal found 6/12$357
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/55:35 amDSM - SJC
1 stop5h 35mAmerican Airlines
dom. 8/106:00 amSJC - DSM
1 stop5h 43mAmerican Airlines
Deal found 6/11$388
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/148:00 amDSM - SFO
2 stops13h 24mUnited Airlines
lun. 8/1811:25 pmSFO - DSM
1 stop9h 14mUnited Airlines
Deal found 6/12$388

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Des Moines to San Francisco Bay Area that are best for you.

Fly from

Des Moines

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

Des MoinesOakland

DSM - OAK

DSMOAK

Des Moines

mié. 7/30

7:30 am-11:33 pm

1 stop18h 03m

Oakland

lun. 8/11

6:00 am-10:38 pm

2 stops14h 38m

$257

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

lun. 7/14

7:33 pm-12:19 am

1 stop6h 46m

San Francisco

vie. 7/18

6:37 am-6:48 pm

1 stop10h 11m

$260

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

mar. 8/5

2:21 pm-11:54 pm

2 stops35h 33m

San Jose

dom. 8/10

6:30 am-12:35 pm

1 stop28h 05m

$279

Des MoinesSan Jose

DSM - SJC

DSMSJC

Des Moines

mar. 7/1

2:20 pm-10:55 pm

1 stop10h 35m

San Jose

sáb. 7/5

6:35 am-6:02 pm

1 stop9h 27m

$297

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

jue. 9/4

6:09 pm-11:09 pm

1 stop7h 00m

San Francisco

mar. 9/9

12:47 am-9:39 am

1 stop6h 52m

$297

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

sáb. 8/16

5:44 am-2:24 pm

1 stop10h 40m

San Francisco

mar. 8/19

12:35 am-10:18 am

1 stop7h 43m

$306

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

mié. 7/23

7:30 am-12:15 pm

1 stop6h 45m

San Francisco

lun. 7/28

10:37 am-10:35 pm

1 stop9h 58m

$316

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

mar. 9/9

12:15 pm-7:50 pm

2 stops9h 35m

San Francisco

sáb. 9/13

6:50 am-8:20 pm

2 stops11h 30m

$325

Des MoinesOakland

DSM - OAK

DSMOAK

Des Moines

mar. 7/1

1:45 pm-7:15 pm

1 stop7h 30m

Oakland

sáb. 7/5

5:10 am-12:10 pm

1 stop5h 00m

$357

Des MoinesSan Francisco

DSM - SFO

DSMSFO

Des Moines

jue. 8/14

8:00 am-7:24 pm

2 stops13h 24m

San Francisco

lun. 8/18

11:25 pm-10:39 am

1 stop9h 14m

$388

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 30 results
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Best time to book a flight from Des Moines to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to San Francisco Bay Area

What is the cheapest month to book a flight from Des Moines to San Francisco Bay Area?

Currently, January is the cheapest month in which you can book a flight from Des Moines to San Francisco Bay Area (average of $276). Flying from Des Moines to San Francisco Bay Area in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to XIH?

Find hourly flight availability from Des Moines to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Des Moines to San Francisco Bay Area, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco Bay Area ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco Bay Area when rainfall is around 0.0 in.

Temperature in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco Bay Area, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Des Moines to San Francisco Bay Area, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Overall

8.0

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to San Francisco Bay Area?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to San Francisco Bay Area. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to San Francisco Bay Area one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $130. American Airlines flights start at $149 while deals on Delta start at $154 one-way.

  • What are the most popular routes from Des Moines to San Francisco Bay Area?

    Most travelers choose Des Moines - San Francisco, Des Moines - San Jose or Des Moines - Oakland when deciding on the best route from Des Moines to San Francisco Bay Area.

  • Can I find deals for flights from Des Moines to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Francisco Bay Area.

  • Can I find deals for business class flights from Des Moines to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Des Moines to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to San Francisco Bay Area?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to San Francisco Bay Area (average of $276). Flying from Des Moines to San Francisco Bay Area in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to San Francisco Bay Area

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to San Francisco Bay Area

Discover the top 5 airlines that operate flights from Des Moines to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$110Average$224FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$250Average$512FlexibilityNo cancel feeOn-time71%
DeltaCheapest$296Average$415FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$296Average$488FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$356Average$458FlexibilityNo cancel feeOn-time63%

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