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$131+ Cheap flights from Panama City, FL to San Diego (ECP - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAN
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amECP - SAN
1 stop8h 03mDelta
Thu 1/18:00 amSAN - ECP
1 stop8h 15mDelta
Deal found 12/10$261
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:15 pmECP - SAN
2 stops7h 55mSouthwest
Thu 1/17:35 amSAN - ECP
1 stop6h 15mSouthwest
Deal found 12/10$425
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:55 pmECP - SAN
1 stop7h 30mSouthwest
Fri 1/26:35 amSAN - ECP
2 stops9h 20mSouthwest
Deal found 12/10$742
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:15 amECP - SAN
2 stops10h 46mUnited Airlines
Sun 12/287:55 pmSAN - ECP
2 stops11h 22mUnited Airlines
Deal found 12/11$782
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/191:30 pmECP - SAN
1 stop9h 05mSouthwest
Sat 1/37:05 amSAN - ECP
2 stops9h 15mSouthwest
Deal found 12/10$792
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:22 amECP - SAN
1 stop7h 59mDelta
Sun 12/2810:30 pmSAN - ECP
1 stop8h 07mDelta
Deal found 12/11$808
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:40 pmECP - SAN
1 stop7h 30mAmerican Airlines
Sat 1/31:36 pmSAN - ECP
1 stop8h 22mAmerican Airlines
Deal found 12/10$827
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:04 pmECP - SAN
1 stop6h 56mDelta
Sat 12/276:15 amSAN - ECP
1 stop7h 09mDelta
Deal found 12/10$888

Find flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$261
(Delta)

One-way from

$131
(Delta)

Popular in

March

Cheapest in

May

Average price

$445
Provider with most accurate pricing for Panama City NW Florida Beaches-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-San Diego flights.
Search Deals
From Panama City NW Florida Beaches to San Diego
Search Deals
One-way flight from Panama City NW Florida Beaches to San Diego
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($110 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 12/25

6:00 am-12:03 pm

1 stop8h 03m

San Diego

Thu 1/1

8:00 am-6:15 pm

1 stop8h 15m

$261

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 2/19

5:00 pm-10:00 pm

1 stop7h 00m

San Diego

Tue 2/24

12:16 pm-7:51 pm

1 stop5h 35m

$372

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 2/14

6:30 am-1:47 pm

1 stop9h 17m

San Diego

Tue 2/17

8:00 am-4:11 pm

1 stop6h 11m

$400

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 2/11

10:30 am-6:30 pm

2 stops10h 00m

San Diego

Mon 2/16

9:10 pm-9:35 am

2 stops10h 25m

$408

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 2/18

2:14 pm-8:37 pm

1 stop8h 23m

$131

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 2/17

3:32 pm-8:25 pm

1 stop6h 53m

$180

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 2/19

2:14 pm-8:37 pm

1 stop8h 23m

$193

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Tue 2/17

12:35 pm-8:00 pm

2 stops9h 25m

$194

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 2/20

10:25 am-7:21 pm

1 stop10h 56m

$219

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 2/15

2:14 pm-8:37 pm

1 stop8h 23m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 15 results
1
2

Compare providers for flights from Panama City to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Diego

What is the cheapest month to book a flight from Panama City, Florida to San Diego?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $122). Flying from Panama City, Florida to San Diego in July is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Panama City, Florida to San Diego is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 7% on airfare.

How much does it cost to fly round-trip from Panama City, Florida to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Panama City to San Diego, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to San Diego?

    Delta and United Airlines can get you from Panama City, Florida to San Diego in just under 7h. Your travel time can differ by up to 1h 03m. There are 1848 mi between Panama City, Florida and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Panama City, Florida to San Diego round-trip?

    Cheapflights users have booked flights from Panama City, Florida to San Diego round-trip from $209. Other airlines that can offer you cheap pricing are United Airlines, from $256, and Southwest, from $260. Delta is 54% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $122). Flying from Panama City, Florida to San Diego in July is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Julian
National City

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Top 4 airlines flying from Panama City to San Diego

Discover the top 4 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$256Average$472FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$260Average$457FlexibilityNo cancel feeOn-time63%
DeltaCheapest$296Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$326Average$416FlexibilityNo cancel feeOn-time71%

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