HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$239+ Cheap flights from Panama City, FL to San Diego (ECP - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$239
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$356
From Panama City NW Florida Beaches to San Diego
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:11 pmECP - SAN
1 stop9h 09mAmerican Airlines
Mon 11/106:46 amSAN - ECP
1 stop8h 29mAmerican Airlines
Deal found 9/10$239
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:08 pmECP - SAN
1 stop6h 37mUnited Airlines
Wed 10/2212:00 pmSAN - ECP
1 stop7h 48mUnited Airlines
Deal found 9/10$297
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:00 amECP - SAN
1 stop10h 45mSouthwest
Mon 11/106:30 amSAN - ECP
2 stops9h 05mSouthwest
Deal found 9/10$301
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/81:55 pmECP - SAN
1 stop10h 19mUnited Airlines
Wed 10/156:15 amSAN - ECP
1 stop8h 01mUnited Airlines
Deal found 9/10$341
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:20 pmECP - SAN
1 stop6h 25mSouthwest
Sat 11/156:25 amSAN - ECP
1 stop8h 35mSouthwest
Deal found 9/9$348
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:00 pmECP - SAN
1 stop6h 53mUnited Airlines
Sun 11/91:47 pmSAN - ECP
1 stop6h 02mUnited Airlines
Deal found 9/10$357

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 11/5

1:11 pm-8:20 pm

1 stop9h 09m

San Diego

Mon 11/10

6:46 am-5:15 pm

1 stop8h 29m

$239

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Thu 10/16

5:08 pm-9:45 pm

1 stop6h 37m

San Diego

Wed 10/22

12:00 pm-9:48 pm

1 stop7h 48m

$297

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 11/5

10:00 am-6:45 pm

1 stop10h 45m

San Diego

Mon 11/10

6:30 am-5:35 pm

2 stops9h 05m

$301

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Wed 10/8

1:55 pm-10:14 pm

1 stop10h 19m

San Diego

Wed 10/15

6:15 am-4:16 pm

1 stop8h 01m

$341

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Mon 11/10

3:20 pm-7:45 pm

1 stop6h 25m

San Diego

Sat 11/15

6:25 am-5:00 pm

1 stop8h 35m

$348

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 11/7

5:00 pm-9:53 pm

1 stop6h 53m

San Diego

Sun 11/9

1:47 pm-9:49 pm

1 stop6h 02m

$357

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Fri 11/28

7:02 am-1:03 pm

1 stop8h 01m

$300

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Mon 12/1

6:40 pm-11:43 pm

1 stop7h 03m

$330

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sat 11/29

4:56 pm-11:43 pm

1 stop8h 47m

$430

Panama CitySan Diego

ECP - SAN

ECPSAN

Panama City NW Florida Beaches

Sun 9/14

6:54 pm-11:24 pm

1 stop6h 30m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Diego

What is the cheapest month to book a flight from Panama City, Florida to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $286). Flying from Panama City, Florida to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Panama City, Florida to San Diego is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 8% on airfare.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Panama City to San Diego, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to San Diego?

    American Airlines, United Airlines, and Southwest can get you from Panama City, Florida to San Diego in just under 6h 37m. Your travel time can differ by up to 4h 08m. There are 1848 mi between Panama City, Florida and San Diego. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Panama City, Florida to San Diego round-trip?

    Cheapflights users have booked flights from Panama City, Florida to San Diego round-trip from $296. Other airlines that can offer you cheap pricing are American Airlines, from $306, and Southwest, from $316. Delta is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $286). Flying from Panama City, Florida to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Las Vegas flights
Fort Lauderdale to Las Vegas flights
Tampa to Las Vegas flights
Miami to Los Angeles flights
Miami to Las Vegas flights
Orlando to Los Angeles flights
Fort Lauderdale to Los Angeles flights
Tampa to Los Angeles flights
Orlando to San Francisco flights
Fort Lauderdale to San Francisco flights
Miami to San Francisco flights
Tampa to San Diego flights
Tampa to San Francisco flights
Miami to Ontario flights
West Palm Beach to Las Vegas flights
Jacksonville to Las Vegas flights
Fort Lauderdale to Burbank flights
Orlando to San Diego flights
Fort Lauderdale to Santa Ana flights
Orlando to Ontario flights
Orlando to Santa Ana flights
Miami to San Diego flights
Tampa to Ontario flights
Tampa to Santa Ana flights
Miami to Santa Ana flights
Fort Lauderdale to Ontario flights
Miami to Burbank flights
Fort Myers to Las Vegas flights
Pensacola to Las Vegas flights
Fort Lauderdale to San Diego flights
Orlando to Burbank flights
Jacksonville to Los Angeles flights
Jacksonville to San Francisco flights
Sarasota to Las Vegas flights
West Palm Beach to Los Angeles flights
Fort Myers to Los Angeles flights
Jacksonville to Ontario flights
Valparaiso to Las Vegas flights
West Palm Beach to San Francisco flights
Pensacola to Los Angeles flights
Gainesville to Las Vegas flights
Orlando to Sacramento flights
Tampa to Burbank flights
Orlando to Oakland flights
Panama City to Las Vegas flights
Pensacola to Ontario flights
Orlando Sanford Intl to Las Vegas flights
Jacksonville to San Diego flights
Miami to San Jose flights
Gainesville to Ontario flights

Top 4 airlines flying from Panama City to San Diego

Discover the top 4 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$434FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$306Average$416FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$316Average$515FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$375Average$486FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.