$229+ Cheap flights from San Diego to Panama City, FL (SAN - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — ECP
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Panama City
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Best
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Cheapest flights from San Diego to Panama CityExplore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:25 pm
SAN
- ECP
1 stop8h 05m
Delta
Mon 6/85:08 pm
ECP
- SAN
1 stop7h 52m
Delta
Deal found 4/25![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:40 pm
SAN
- ECP
1 stop8h 50m
Southwest
Mon 6/86:55 am
ECP
- SAN
2 stops8h 20m
Southwest
Deal found 4/25![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:05 am
SAN
- ECP
1 stop12h 05m
Southwest
Tue 7/710:25 am
ECP
- SAN
2 stops9h 55m
Southwest
Deal found 4/25![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:20 pm
SAN
- ECP
1 stop6h 40m
Southwest
Tue 6/3012:50 pm
ECP
- SAN
2 stops9h 30m
Southwest
Deal found 4/26![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:40 am
SAN
- ECP
1 stop8h 55m
Southwest
Mon 10/196:30 am
ECP
- SAN
1 stop8h 30m
Southwest
Deal found 4/28![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:00 pm
SAN
- ECP
1 stop7h 40m
Southwest
Sun 6/77:10 pm
ECP
- SAN
1 stop6h 05m
Southwest
Deal found 4/25![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:20 pm
SAN
- ECP
1 stop6h 40m
Southwest
Tue 7/710:25 am
ECP
- SAN
2 stops9h 55m
Southwest
Deal found 4/24![Southwest logo]()
$432
Best flights from San Diego to Panama CityDiscover carefully curated flight deals from San Diego to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from San Diego to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:50 am
SAN
- ECP
2 stops11h 00m
Southwest
Mon 6/86:55 am
ECP
- SAN
2 stops8h 20m
Southwest
Deal found 4/25![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:30 pm
SAN
- ECP
1 stop7h 50m
Delta
Thu 7/162:43 pm
ECP
- SAN
1 stop8h 29m
Delta
Deal found 4/24![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:40 pm
SAN
- ECP
1 stop9h 13m
United Airlines
Tue 5/196:30 am
ECP
- SAN
1 stop9h 20m
United Airlines
Deal found 4/26![United Airlines logo]()
$476
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:20 pm
SAN
- ECP
1 stop6h 40m
Southwest
Tue 6/3012:50 pm
ECP
- SAN
2 stops9h 30m
Southwest
Deal found 4/26![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:15 am
SAN
- ECP
1 stop8h 15m
Southwest
Sun 6/75:40 am
ECP
- SAN
2 stops9h 10m
Southwest
Deal found 4/25![Southwest logo]()
$433
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:15 am
SAN
- ECP
2 stops10h 25m
Southwest
Tue 7/710:25 am
ECP
- SAN
2 stops9h 55m
Southwest
Deal found 4/24![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:55 pm
SAN
- ECP
1 stop5h 45m
Southwest
Mon 7/132:55 pm
ECP
- SAN
1 stop6h 10m
Southwest
Deal found 4/27![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:40 pm
SAN
- ECP
1 stop8h 50m
Southwest
Fri 5/225:00 pm
ECP
- SAN
1 stop8h 10m
Southwest
Deal found 4/27![Southwest logo]()
$458
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:35 am
SAN
- ECP
1 stop9h 25m
Southwest
Sun 6/285:35 am
ECP
- SAN
2 stops9h 15m
Southwest
Deal found 4/26![Southwest logo]()
$462
Last-minute flights from San Diego to Panama CityDiscover last-minute flight deals from San Diego to Panama City. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Panama City. Data last updated April 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:15 am
SAN
- ECP
1 stop8h 03m
United Airlines
Wed 5/136:30 am
ECP
- SAN
1 stop6h 33m
United Airlines
Deal found 4/24![United Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:40 pm
SAN
- ECP
1 stop9h 13m
United Airlines
Tue 5/196:30 am
ECP
- SAN
1 stop9h 20m
United Airlines
Deal found 4/26![United Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:04 pm
SAN
- ECP
1 stop6h 09m
American Airlines
Tue 5/1911:43 am
ECP
- SAN
2 stops10h 50m
American Airlines
Deal found 4/26![American Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:35 am
SAN
- ECP
2 stops9h 50m
Southwest
Tue 5/197:55 am
ECP
- SAN
2 stops8h 25m
Southwest
Deal found 4/26![Southwest logo]()
$498
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:40 pm
SAN
- ECP
1 stop8h 50m
Southwest
Fri 5/225:00 pm
ECP
- SAN
1 stop8h 10m
Southwest
Deal found 4/27![Southwest logo]()
$458
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:10 am
SAN
- ECP
1 stop7h 05m
Southwest
Sun 5/246:35 am
ECP
- SAN
1 stop6h 20m
Southwest
Deal found 4/28![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:55 am
SAN
- ECP
2 stops7h 55m
Southwest
Sun 5/246:35 am
ECP
- SAN
1 stop6h 20m
Southwest
Deal found 4/25![Southwest logo]()
$562
One-way flights from San Diego to Panama CitySearch for one-way flight options from San Diego to Panama City. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from San Diego to Panama City. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:15 am
SAN
- ECP
1 stop6h 07m
American Airlines
Deal found 4/28![American Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:00 am
SAN
- ECP
2 stops11h 40m
Southwest
Deal found 4/26![Southwest logo]()
$240
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:20 pm
SAN
- ECP
1 stop8h 13m
American Airlines
Deal found 4/24![American Airlines logo]()
$270
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:28 pm
SAN
- ECP
2 stops14h 35m
United Airlines
Deal found 4/28![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
SAN
- ECP
1 stop9h 09m
Delta
Deal found 4/26![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:45 am
SAN
- ECP
2 stops7h 40m
Southwest
Deal found 4/26![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:27 pm
SAN
- ECP
3 stops25h 31m
United Airlines
Deal found 4/26![United Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:27 pm
SAN
- ECP
3 stops25h 31m
United Airlines
Deal found 4/26![United Airlines logo]()
$594
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:15 am
SAN
- ECP
2 stops8h 39m
Delta
Deal found 4/26![Delta logo]()
$828
Find flight deals from San Diego to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (Delta) |
One-way from | $229 (American Airlines) |
Popular in | July |
Cheapest in | January |
Average price | $517 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Mon 6/1
6:50 am-7:50 pm
2 stops11h 00m
Panama City NW Florida Beaches
Mon 6/8
6:55 am-1:15 pm
2 stops8h 20m
$409
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Thu 6/25
1:20 pm-10:00 pm
1 stop6h 40m
Panama City NW Florida Beaches
Tue 6/30
12:50 pm-8:20 pm
2 stops9h 30m
$421
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Mon 6/1
11:15 am-9:30 pm
1 stop8h 15m
Panama City NW Florida Beaches
Sun 6/7
5:40 am-12:50 pm
2 stops9h 10m
$433
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Fri 7/3
9:15 am-9:40 pm
2 stops10h 25m
Panama City NW Florida Beaches
Tue 7/7
10:25 am-6:20 pm
2 stops9h 55m
$443
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Fri 7/10
10:30 pm-8:20 am
1 stop7h 50m
Panama City NW Florida Beaches
Thu 7/16
2:43 pm-9:12 pm
1 stop8h 29m
$457
Quickest round-trip
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Fri 7/10
1:55 pm-9:40 pm
1 stop5h 45m
Panama City NW Florida Beaches
Mon 7/13
2:55 pm-7:05 pm
1 stop6h 10m
$457
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Mon 5/18
10:40 pm-9:30 am
1 stop8h 50m
Panama City NW Florida Beaches
Fri 5/22
5:00 pm-11:10 pm
1 stop8h 10m
$458
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Thu 6/25
10:35 am-10:00 pm
1 stop9h 25m
Panama City NW Florida Beaches
Sun 6/28
5:35 am-12:50 pm
2 stops9h 15m
$462
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Sat 5/16
10:40 pm-9:53 am
1 stop9h 13m
Panama City NW Florida Beaches
Tue 5/19
6:30 am-1:50 pm
1 stop9h 20m
$476
Cheapest one-way
Quickest one-way
San DiegoPanama City
SAN - ECP
SANECP
San Diego
Sat 8/15
6:15 am-2:22 pm
1 stop6h 07m
$229
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from San Diego to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Panama City in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Diego with our price prediction graph.
SAN-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Panama City
What is the cheapest month to book a flight from San Diego to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Diego to Panama City, Florida (average of $290). Flying from San Diego to Panama City, Florida in July is currently the most expensive (average of $758). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 29, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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San Diego and Panama City flights
Browse other San Diego and Panama City flight options. Last updated on April 29, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Diego to Panama City
Discover the top 4 airlines that operate flights from San Diego to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$200 | Average$578 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$404 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$562 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$375 | Average$486 | FlexibilityNo cancel fee | On-time63% |