$169+ Cheap flights from San Diego to Panama City, FL (SAN - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — ECP
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Panama City
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Cheapest flights from San Diego to Panama CityExplore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Mon 10/196:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:25 pm -
1 stop7h 49m
Thu 10/226:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$352
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:15 am -
1 stop9h 12m
Thu 11/193:56 pm -
1 stop7h 59m
Deal found 9/5![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:36 pm -
2 stops16h 38m
Thu 10/224:30 pm -
1 stop8h 54m
Deal found 9/9![Delta logo]()
$418
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:40 am -
2 stops8h 55m
Thu 11/1910:05 am -
1 stop8h 35m
Deal found 9/5![Southwest logo]()
$419
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Wed 10/219:19 am -
1 stop9h 06m
Deal found 9/9![Delta logo]()
$432
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:15 am -
2 stops15h 03m
Mon 10/196:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:25 pm -
1 stop7h 49m
Wed 10/219:19 am -
1 stop9h 06m
Deal found 9/9![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 pm -
1 stop8h 29m
Mon 10/266:20 pm -
1 stop7h 04m
Deal found 9/5![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:58 am -
1 stop9h 55m
Tue 10/207:12 pm -
1 stop6h 26m
Deal found 9/9![American Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Thu 10/226:20 pm -
2 stops22h 59m
Deal found 9/9![Delta logo]()
$464
Best flights from San Diego to Panama CityDiscover carefully curated flight deals from San Diego to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from San Diego to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:40 am -
2 stops8h 55m
Thu 11/197:30 am -
2 stops9h 50m
Deal found 9/5![Southwest logo]()
$424
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:15 am -
1 stop9h 30m
Wed 12/309:55 am -
1 stop8h 55m
Deal found 9/7![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:15 am -
1 stop9h 30m
Mon 11/308:00 pm -
1 stop5h 55m
Deal found 9/6![Southwest logo]()
$492
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:20 pm -
1 stop6h 15m
Fri 9/256:00 am -
1 stop7h 10m
Deal found 9/8![Southwest logo]()
$513
Last-minute flights from San Diego to Panama CityDiscover last-minute flight deals from San Diego to Panama City. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Panama City. Data last updated September 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:55 am -
1 stop5h 55m
Sat 9/265:15 pm -
1 stop5h 45m
Deal found 9/9![Southwest logo]()
$474
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:15 am -
2 stops15h 03m
Thu 10/226:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:36 pm -
2 stops16h 38m
Thu 10/224:30 pm -
1 stop8h 54m
Deal found 9/9![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Mon 10/196:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Wed 10/219:19 am -
1 stop9h 06m
Deal found 9/9![Delta logo]()
$432
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Thu 10/226:20 pm -
2 stops22h 59m
Deal found 9/9![Delta logo]()
$464
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:25 pm -
1 stop7h 49m
Thu 10/226:20 pm -
1 stop7h 04m
Deal found 9/9![Delta logo]()
$352
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:25 pm -
1 stop7h 49m
Wed 10/219:19 am -
1 stop9h 06m
Deal found 9/9![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:58 am -
1 stop9h 55m
Tue 10/207:12 pm -
1 stop6h 26m
Deal found 9/9![American Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 pm -
1 stop8h 29m
Mon 10/266:20 pm -
1 stop7h 04m
Deal found 9/5![Delta logo]()
$448
One-way flights from San Diego to Panama CitySearch for one-way flight options from San Diego to Panama City. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from San Diego to Panama City. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:25 pm -
1 stop7h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$169
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:25 pm -
1 stop7h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$184
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:30 pm -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$204
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:20 pm -
1 stop6h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$225
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:57 pm -
2 stops11h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:15 am -
1 stop9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$239
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:58 am -
1 stop9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$256
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:15 am -
1 stop6h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:15 am -
2 stops15h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$276
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:40 pm -
1 stop8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Southwest logo]()
$314
Find flight deals from San Diego to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Delta) |
One-way from | $169 (Delta) |
Popular in | February |
Cheapest in | January |
Average price | $486 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Tue 12/22
10:30 pm-8:43 am
1 stop8h 13m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$204
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Tue 9/22
12:20 pm-8:35 pm
1 stop6h 15m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Wed 12/23
6:15 am-5:45 pm
1 stop9h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$239
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Fri 10/16
3:59 pm-8:14 am
2 stops14h 15m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$252
Quickest round-trip
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Wed 9/30
6:15 am-2:22 pm
1 stop6h 07m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$264
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Mon 9/21
10:30 pm-8:16 am
1 stop7h 46m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$371
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Mon 9/21
6:40 am-7:05 pm
2 stops10h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$376
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Sat 11/14
6:40 am-5:35 pm
2 stops8h 55m
Panama City NW Florida Beaches
Thu 11/19
7:30 am-3:20 pm
2 stops9h 50m
$424
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Wed 12/23
6:15 am-5:45 pm
1 stop9h 30m
Panama City NW Florida Beaches
Wed 12/30
9:55 am-4:50 pm
1 stop8h 55m
$472
San DiegoPanama City
SAN San Diego - ECP Panama City NW Florida Beaches
SANECP
San Diego
Wed 11/25
6:15 am-5:45 pm
1 stop9h 30m
Panama City NW Florida Beaches
Mon 11/30
8:00 pm-11:55 pm
1 stop5h 55m
$492
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from San Diego to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Diego with our price prediction graph.
SAN-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 10, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from San Diego to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Food
7.0
Entertainment
7.5
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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San Diego and Panama City flights
Browse other San Diego and Panama City flight options. Last updated on September 10, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Diego to Panama City
Discover the top 3 airlines that operate flights from San Diego to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$200 | Average$458 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$210 | Average$537 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$310 | Average$486 | FlexibilityNo cancel fee | On-time63% |