$163+ Cheap flights from Panama City, FL to San Diego (ECP - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAN
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Panama City to San DiegoExplore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:38 pm -
1 stop9h 41m
Wed 12/166:20 am -
1 stop6h 41m
Deal found 10/29![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:06 pm -
1 stop9h 32m
Tue 12/156:20 am -
1 stop6h 41m
Deal found 10/29![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:05 pm -
1 stop8h 21m
Wed 11/186:20 am -
2 stops7h 58m
Deal found 10/26![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop7h 38m
Sat 11/142:33 pm -
1 stop6h 51m
Deal found 10/26![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:04 am -
1 stop6h 50m
Mon 12/146:20 am -
1 stop6h 41m
Deal found 10/29![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:55 pm -
1 stop6h 31m
Sat 11/146:20 am -
2 stops7h 58m
Deal found 10/26![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:06 pm -
1 stop9h 32m
Sun 12/139:50 pm -
1 stop8h 48m
Deal found 10/29![Delta logo]()
$363
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:30 pm -
2 stops12h 49m
Sun 12/138:00 am -
1 stop6h 13m
Deal found 10/26![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:55 am -
2 stops9h 25m
Wed 11/1810:55 am -
2 stops7h 40m
Deal found 10/26![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:22 am -
2 stops13h 30m
Thu 12/179:50 pm -
1 stop8h 48m
Deal found 10/29![Delta logo]()
$380
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:55 pm -
1 stop8h 30m
Tue 12/2210:35 pm -
1 stop8h 45m
Deal found 10/29![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/141:38 pm -
1 stop9h 41m
Tue 12/229:50 pm -
1 stop8h 47m
Deal found 10/29![Delta logo]()
$382
Best flights from Panama City to San DiegoDiscover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:38 pm -
1 stop8h 23m
Wed 12/169:50 pm -
1 stop8h 48m
Deal found 10/29![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:10 pm -
1 stop9h 00m
Sun 12/138:20 am -
1 stop7h 00m
Deal found 10/26![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:30 pm -
2 stops12h 49m
Sun 12/138:00 am -
1 stop6h 13m
Deal found 10/26![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:06 pm -
1 stop7h 13m
Wed 12/169:50 pm -
1 stop8h 48m
Deal found 10/29![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
1 stop7h 54m
Tue 12/159:50 pm -
1 stop8h 48m
Deal found 10/29![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop7h 38m
Sat 11/142:33 pm -
1 stop6h 51m
Deal found 10/26![Delta logo]()
$343
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:00 pm -
2 stops10h 25m
Sun 1/38:35 am -
2 stops8h 45m
Deal found 10/28![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/133:25 pm -
2 stops9h 35m
Sat 3/206:30 am -
2 stops9h 15m
Deal found 10/27![Southwest logo]()
$471
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:38 pm -
1 stop8h 23m
Thu 12/106:47 pm -
2 stops11h 51m
Deal found 10/29![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:05 pm -
1 stop8h 21m
Wed 11/1112:05 pm -
1 stop7h 31m
Deal found 10/27![United Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:58 pm -
1 stop10h 35m
Mon 12/212:45 pm -
2 stops18h 01m
Deal found 10/29![United Airlines logo]()
$569
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:10 am -
2 stops9h 50m
Mon 11/308:35 am -
2 stops8h 45m
Deal found 10/27![Southwest logo]()
$558
Last-minute flights from Panama City to San DiegoDiscover last-minute flight deals from Panama City to San Diego. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Diego. Data last updated October 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop7h 13m
Wed 11/1112:48 pm -
1 stop8h 36m
Deal found 10/28![Delta logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:30 am -
2 stops11h 06m
Wed 11/1112:05 pm -
1 stop7h 31m
Deal found 10/28![United Airlines logo]()
$487
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop7h 38m
Sat 11/142:33 pm -
1 stop6h 51m
Deal found 10/26![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:55 pm -
1 stop6h 31m
Sat 11/146:20 am -
2 stops7h 58m
Deal found 10/26![United Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am -
2 stops8h 35m
Sat 11/145:45 pm -
2 stops13h 50m
Deal found 10/26![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:05 pm -
1 stop7h 55m
Mon 11/169:15 am -
2 stops9h 20m
Deal found 10/28![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:05 pm -
2 stops9h 25m
Mon 11/166:20 am -
2 stops7h 58m
Deal found 10/28![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:05 pm -
1 stop8h 21m
Wed 11/1812:05 pm -
1 stop7h 31m
Deal found 10/26![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:55 am -
2 stops9h 25m
Wed 11/1810:55 am -
2 stops7h 40m
Deal found 10/26![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:25 pm -
1 stop9h 05m
Mon 11/3010:35 pm -
1 stop8h 55m
Deal found 10/27![Southwest logo]()
$446
One-way flights from Panama City to San DiegoSearch for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:06 am -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$163
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 pm -
1 stop5h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$172
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:50 pm -
2 stops9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$177
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:35 pm -
1 stop8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:30 am -
2 stops11h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$316
This deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:05 pm -
1 stop8h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:05 pm -
2 stops11h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:30 am -
3 stops14h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:00 am -
3 stops19h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$932
Find flight deals from Panama City to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $325 (Delta) |
One-way from | $163 (United Airlines) |
Popular in | January |
Cheapest in | December |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Thu 11/19
9:06 am-6:37 pm
2 stops11h 31m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$168
Quickest round-trip
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Wed 12/23
8:00 pm-11:55 pm
1 stop5h 55m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$172
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Wed 12/23
8:06 am-3:41 pm
1 stop9h 35m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$172
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Thu 11/12
3:05 pm-9:26 pm
1 stop8h 21m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$172
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Wed 12/23
4:50 pm-11:51 pm
2 stops9h 01m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$177
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Sat 11/7
1:35 pm-8:30 pm
1 stop8h 55m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$311
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Sat 11/7
11:30 am-8:36 pm
2 stops11h 06m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$316
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Wed 12/9
1:38 pm-8:01 pm
1 stop8h 23m
San Diego
Wed 12/16
9:50 pm-8:38 am
1 stop8h 48m
$325
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Thu 12/10
4:06 pm-9:19 pm
1 stop7h 13m
San Diego
Wed 12/16
9:50 pm-8:38 am
1 stop8h 48m
$325
Panama CitySan Diego
ECP Panama City NW Florida Beaches - SAN San Diego
ECPSAN
Panama City NW Florida Beaches
Tue 12/15
6:00 am-11:54 am
1 stop7h 54m
San Diego
Tue 12/15
9:50 pm-8:38 am
1 stop8h 48m
$325
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
ECP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Diego
What is the cheapest month to book a flight from Panama City, Florida to San Diego?
Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $260). Flying from Panama City, Florida to San Diego in January is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Diego?
Airfare is below average for this route at the moment.
Panama City, Florida to San Diego flights typically cost between $427 and $526 in December.The cheapest round-trip price found within the last 5 days was $325 on Delta (Dec 8-Dec 16).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 30, 2026.
Read through reviews of airlines operating flights from Panama City to San Diego, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
San Ysidro
Poway
Coronado
La Mesa
Julian
Santee
Lemon Grove
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Panama City and San Diego flights
Browse other Panama City and San Diego flight options. Last updated on October 30, 2026.
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Top 3 airlines flying from Panama City to San Diego
Discover the top 3 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$260 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$486 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$384 | Average$537 | FlexibilityNo cancel fee | On-time63% |