$156+ Cheap flights from Panama City, FL to San Diego (ECP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAN
Sep 1 — Sep 81
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to San Diego
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Best
Last-minute
One-way
Cheapest flights from Panama City to San DiegoExplore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:10 pm
ECP
- SAN
1 stop8h 50m
Delta
Sat 8/2912:34 pm
SAN
- ECP
1 stop7h 06m
Delta
Deal found 7/28![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 am
ECP
- SAN
2 stops9h 50m
Southwest
Tue 12/298:35 am
SAN
- ECP
2 stops8h 40m
Southwest
Deal found 7/28![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ECP
- SAN
1 stop7h 40m
Delta
Wed 9/912:52 pm
SAN
- ECP
1 stop8h 13m
Delta
Deal found 7/31![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:50 am
ECP
- SAN
2 stops8h 05m
Southwest
Wed 9/98:35 am
SAN
- ECP
1 stop10h 00m
Southwest
Deal found 7/31![Southwest logo]()
$340
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 pm
ECP
- SAN
1 stop6h 05m
Southwest
Fri 10/237:20 am
SAN
- ECP
1 stop7h 45m
Southwest
Deal found 7/30![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:11 am
ECP
- SAN
1 stop9h 39m
American Airlines
Mon 12/76:15 am
SAN
- ECP
1 stop6h 30m
American Airlines
Deal found 8/1![American Airlines logo]()
$377
Best flights from Panama City to San DiegoDiscover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
Discover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:10 pm
ECP
- SAN
1 stop8h 50m
Delta
Sat 8/2912:34 pm
SAN
- ECP
1 stop7h 06m
Delta
Deal found 7/28![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 am
ECP
- SAN
2 stops9h 50m
Southwest
Tue 12/296:35 am
SAN
- ECP
1 stop10h 40m
Southwest
Deal found 7/28![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:55 pm
ECP
- SAN
1 stop6h 31m
United Airlines
Sat 11/1412:05 pm
SAN
- ECP
1 stop7h 31m
United Airlines
Deal found 7/30![United Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 pm
ECP
- SAN
1 stop6h 05m
Southwest
Fri 10/237:20 am
SAN
- ECP
1 stop7h 45m
Southwest
Deal found 7/30![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:34 pm
ECP
- SAN
1 stop9h 44m
Delta
Thu 11/266:15 am
SAN
- ECP
1 stop6h 51m
Delta
Deal found 8/1![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:50 am
ECP
- SAN
2 stops8h 05m
Southwest
Wed 9/98:05 am
SAN
- ECP
2 stops8h 45m
Southwest
Deal found 7/31![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:31 am
ECP
- SAN
1 stop7h 34m
Delta
Fri 9/410:25 pm
SAN
- ECP
1 stop8h 06m
Delta
Deal found 8/1![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:30 am
ECP
- SAN
2 stops9h 50m
Southwest
Mon 12/76:30 am
SAN
- ECP
1 stop6h 40m
Southwest
Deal found 8/1![Southwest logo]()
$382
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
ECP
- SAN
1 stop7h 07m
Delta
Tue 8/2510:25 pm
SAN
- ECP
1 stop8h 06m
Delta
Deal found 8/1![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:50 pm
ECP
- SAN
1 stop6h 05m
Southwest
Fri 11/276:55 am
SAN
- ECP
1 stop7h 45m
Southwest
Deal found 8/1![Southwest logo]()
$409
Last-minute flights from Panama City to San DiegoDiscover last-minute flight deals from Panama City to San Diego. Data last updated August 2, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Diego. Data last updated August 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
ECP
- SAN
1 stop7h 07m
Delta
Tue 8/2510:25 pm
SAN
- ECP
1 stop8h 06m
Delta
Deal found 8/1![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:10 pm
ECP
- SAN
1 stop8h 50m
Delta
Sat 8/2912:34 pm
SAN
- ECP
1 stop7h 06m
Delta
Deal found 7/28![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:47 pm
ECP
- SAN
1 stop10h 23m
United Airlines
Sat 8/296:28 pm
SAN
- ECP
2 stops14h 36m
United Airlines
Deal found 7/29![United Airlines logo]()
$416
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:00 am
ECP
- SAN
1 stop8h 55m
Southwest
Sun 8/309:25 am
SAN
- ECP
1 stop6h 50m
Southwest
Deal found 7/30![Southwest logo]()
$389
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:00 am
ECP
- SAN
1 stop8h 55m
Southwest
Fri 9/410:40 pm
SAN
- ECP
1 stop8h 20m
Southwest
Deal found 7/31![Southwest logo]()
$433
One-way flights from Panama City to San DiegoSearch for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
Search for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
ECP
- SAN
1 stop8h 33m
Delta
Deal found 7/29![Delta logo]()
$156
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am
ECP
- SAN
1 stop6h 20m
Southwest
Deal found 7/31![Southwest logo]()
$174
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:40 am
ECP
- SAN
1 stop8h 08m
American Airlines
Deal found 7/31![American Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:25 pm
ECP
- SAN
1 stop7h 30m
Southwest
Deal found 7/31![Southwest logo]()
$234
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:41 am
ECP
- SAN
2 stops11h 04m
United Airlines
Deal found 7/31![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:17 pm
ECP
- SAN
1 stop6h 44m
American Airlines
Deal found 7/30![American Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:35 am
ECP
- SAN
1 stop6h 58m
Delta
Deal found 8/2![Delta logo]()
$371
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:27 pm
ECP
- SAN
2 stops10h 00m
United Airlines
Deal found 8/2![United Airlines logo]()
$376
Find flight deals from Panama City to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Delta) |
One-way from | $156 (Delta) |
Popular in | March |
Cheapest in | October |
Average price | $487 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Mon 8/24
4:10 pm-11:00 pm
1 stop8h 50m
San Diego
Sat 8/29
12:34 pm-9:40 pm
1 stop7h 06m
$311
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Tue 12/22
6:20 am-2:10 pm
2 stops9h 50m
San Diego
Tue 12/29
6:35 am-7:15 pm
1 stop10h 40m
$322
Quickest round-trip
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Wed 10/21
6:00 pm-10:05 pm
1 stop6h 05m
San Diego
Fri 10/23
7:20 am-5:05 pm
1 stop7h 45m
$359
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Sun 9/6
6:50 am-12:55 pm
2 stops8h 05m
San Diego
Wed 9/9
8:05 am-6:50 pm
2 stops8h 45m
$379
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Fri 12/4
7:30 am-3:20 pm
2 stops9h 50m
San Diego
Mon 12/7
6:30 am-3:10 pm
1 stop6h 40m
$382
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Fri 11/20
1:34 pm-9:18 pm
1 stop9h 44m
San Diego
Thu 11/26
6:15 am-3:06 pm
1 stop6h 51m
$389
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Tue 9/1
11:31 am-5:05 pm
1 stop7h 34m
San Diego
Fri 9/4
10:25 pm-8:31 am
1 stop8h 06m
$403
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Sun 8/23
6:00 am-11:07 am
1 stop7h 07m
San Diego
Tue 8/25
10:25 pm-8:31 am
1 stop8h 06m
$407
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Sat 11/21
7:50 pm-11:55 pm
1 stop6h 05m
San Diego
Fri 11/27
6:55 am-4:40 pm
1 stop7h 45m
$409
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Wed 11/11
4:55 pm-9:26 pm
1 stop6h 31m
San Diego
Sat 11/14
12:05 pm-9:36 pm
1 stop7h 31m
$411
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
ECP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Diego
What is the cheapest month to book a flight from Panama City, Florida to San Diego?
Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $347). Flying from Panama City, Florida to San Diego in March is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Diego?
Airfare is below average for this route at the moment.
Panama City, Florida to San Diego flights typically cost between $457 and $658 in January.The cheapest round-trip price found within the last 5 days was $311 on Delta (Jan 26-Feb 3).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated August 2, 2026.
Read through reviews of airlines operating flights from Panama City to San Diego, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
La Mesa
Coronado
Santee
San Ysidro
Julian
Lemon Grove
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Panama City and San Diego flights
Browse other Panama City and San Diego flight options. Last updated on August 2, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on August 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 2, 2026.
Top 4 airlines flying from Panama City to San Diego
Discover the top 4 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$256 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$260 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$455 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$384 | Average$505 | FlexibilityNo cancel fee | On-time63% |