$176+ Cheap flights from Panama City, FL to San Diego (ECP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SAN
Jul 7 — Jul 141
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Best
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Cheapest flights from Panama City to San DiegoExplore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:03 pm
ECP
- SAN
1 stop7h 54m
Delta
Thu 8/69:30 pm
SAN
- ECP
1 stop9h 01m
Delta
Deal found 6/7![Delta logo]()
$351
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:36 pm
ECP
- SAN
1 stop7h 59m
Delta
Wed 8/512:32 pm
SAN
- ECP
1 stop7h 08m
Delta
Deal found 6/4![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:45 am
ECP
- SAN
1 stop9h 56m
Delta
Tue 10/139:40 pm
SAN
- ECP
1 stop8h 37m
Delta
Deal found 6/4![Delta logo]()
$405
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:20 pm
ECP
- SAN
2 stops9h 35m
Southwest
Wed 8/57:20 am
SAN
- ECP
1 stop8h 50m
Southwest
Deal found 6/4![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:10 am
ECP
- SAN
1 stop8h 10m
Southwest
Sat 10/1010:40 pm
SAN
- ECP
1 stop8h 35m
Southwest
Deal found 6/4![Southwest logo]()
$410
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
ECP
- SAN
1 stop8h 33m
Delta
Sat 8/2912:34 pm
SAN
- ECP
1 stop7h 06m
Delta
Deal found 6/2![Delta logo]()
$425
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:56 pm
ECP
- SAN
1 stop7h 03m
American Airlines
Mon 7/1312:20 pm
SAN
- ECP
1 stop7h 19m
American Airlines
Deal found 6/3![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:56 pm
ECP
- SAN
1 stop7h 03m
American Airlines
Wed 8/510:59 am
SAN
- ECP
2 stops9h 41m
American Airlines
Deal found 6/4![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:17 pm
ECP
- SAN
1 stop7h 28m
American Airlines
Mon 7/610:28 pm
SAN
- ECP
1 stop9h 59m
American Airlines
Deal found 6/6![American Airlines logo]()
$434
Best flights from Panama City to San DiegoDiscover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
Discover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:03 pm
ECP
- SAN
1 stop7h 54m
Delta
Thu 8/69:30 pm
SAN
- ECP
1 stop9h 01m
Delta
Deal found 6/7![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:15 am
ECP
- SAN
2 stops10h 30m
Southwest
Wed 8/58:05 am
SAN
- ECP
2 stops8h 40m
Southwest
Deal found 6/4![Southwest logo]()
$411
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3011:00 am
ECP
- SAN
1 stop9h 50m
American Airlines
Wed 8/56:19 am
SAN
- ECP
1 stop9h 14m
American Airlines
Deal found 6/3![American Airlines logo]()
$426
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:36 pm
ECP
- SAN
1 stop7h 59m
Delta
Wed 8/512:32 pm
SAN
- ECP
1 stop7h 08m
Delta
Deal found 6/4![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:17 pm
ECP
- SAN
1 stop7h 28m
American Airlines
Mon 7/610:28 pm
SAN
- ECP
1 stop9h 59m
American Airlines
Deal found 6/6![American Airlines logo]()
$434
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:25 am
ECP
- SAN
1 stop8h 00m
Southwest
Mon 11/167:05 am
SAN
- ECP
1 stop9h 10m
Southwest
Deal found 6/6![Southwest logo]()
$457
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:10 pm
ECP
- SAN
1 stop8h 53m
Delta
Thu 10/89:40 pm
SAN
- ECP
1 stop8h 37m
Delta
Deal found 6/4![Delta logo]()
$420
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:55 am
ECP
- SAN
2 stops8h 15m
Southwest
Fri 7/171:55 pm
SAN
- ECP
1 stop5h 50m
Southwest
Deal found 6/3![Southwest logo]()
$462
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
ECP
- SAN
1 stop8h 33m
Delta
Sat 8/2912:34 pm
SAN
- ECP
1 stop7h 06m
Delta
Deal found 6/2![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:55 am
ECP
- SAN
2 stops8h 50m
Southwest
Fri 7/310:40 pm
SAN
- ECP
1 stop9h 00m
Southwest
Deal found 6/6![Southwest logo]()
$484
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:10 pm
ECP
- SAN
1 stop8h 53m
Delta
Mon 10/1210:40 pm
SAN
- ECP
1 stop7h 37m
Delta
Deal found 6/4![Delta logo]()
$451
Last-minute flights from Panama City to San DiegoDiscover last-minute flight deals from Panama City to San Diego. Data last updated June 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Diego. Data last updated June 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:17 pm
ECP
- SAN
1 stop7h 28m
American Airlines
Mon 7/610:28 pm
SAN
- ECP
1 stop9h 59m
American Airlines
Deal found 6/6![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:56 pm
ECP
- SAN
1 stop7h 03m
American Airlines
Mon 7/1312:20 pm
SAN
- ECP
1 stop7h 19m
American Airlines
Deal found 6/3![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:55 pm
ECP
- SAN
1 stop5h 55m
Southwest
Thu 7/2310:40 pm
SAN
- ECP
1 stop8h 55m
Southwest
Deal found 6/5![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/271:20 pm
ECP
- SAN
1 stop7h 25m
Southwest
Sun 8/210:40 pm
SAN
- ECP
1 stop10h 10m
Southwest
Deal found 6/4![Southwest logo]()
$454
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:03 pm
ECP
- SAN
1 stop7h 54m
Delta
Thu 8/69:30 pm
SAN
- ECP
1 stop9h 01m
Delta
Deal found 6/7![Delta logo]()
$351
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:36 pm
ECP
- SAN
1 stop7h 59m
Delta
Wed 8/512:32 pm
SAN
- ECP
1 stop7h 08m
Delta
Deal found 6/4![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:20 pm
ECP
- SAN
2 stops9h 35m
Southwest
Wed 8/57:20 am
SAN
- ECP
1 stop8h 50m
Southwest
Deal found 6/4![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:56 pm
ECP
- SAN
1 stop7h 03m
American Airlines
Wed 8/510:59 am
SAN
- ECP
2 stops9h 41m
American Airlines
Deal found 6/4![American Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:55 pm
ECP
- SAN
1 stop7h 20m
Southwest
Thu 8/610:15 am
SAN
- ECP
2 stops9h 20m
Southwest
Deal found 6/4![Southwest logo]()
$443
One-way flights from Panama City to San DiegoSearch for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
Search for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:41 am
ECP
- SAN
1 stop8h 05m
United Airlines
Deal found 6/5![United Airlines logo]()
$176
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:16 pm
ECP
- SAN
1 stop7h 32m
American Airlines
Deal found 6/3![American Airlines logo]()
$198
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:08 pm
ECP
- SAN
1 stop7h 52m
Delta
Deal found 6/6![Delta logo]()
$203
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:35 pm
ECP
- SAN
1 stop5h 40m
Southwest
Deal found 6/3![Southwest logo]()
$224
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:05 pm
ECP
- SAN
1 stop10h 29m
United Airlines
Deal found 6/6![United Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:00 am
ECP
- SAN
2 stops7h 15m
Southwest
Deal found 6/3![Southwest logo]()
$245
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:55 pm
ECP
- SAN
1 stop8h 25m
Southwest
Deal found 6/3![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:20 pm
ECP
- SAN
1 stop7h 25m
Southwest
Deal found 6/6![Southwest logo]()
$366
Find flight deals from Panama City to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $351 (Delta) |
One-way from | $176 (United Airlines) |
Popular in | March |
Cheapest in | September |
Average price | $447 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 7/30
5:03 pm-10:57 pm
1 stop7h 54m
San Diego
Thu 8/6
9:30 pm-8:31 am
1 stop9h 01m
$351
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 7/30
1:36 pm-7:35 pm
1 stop7h 59m
San Diego
Wed 8/5
12:32 pm-9:40 pm
1 stop7h 08m
$361
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 7/30
10:15 am-6:45 pm
2 stops10h 30m
San Diego
Wed 8/5
8:05 am-6:45 pm
2 stops8h 40m
$411
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Wed 10/7
4:10 pm-11:03 pm
1 stop8h 53m
San Diego
Thu 10/8
9:40 pm-8:17 am
1 stop8h 37m
$420
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Mon 8/24
6:00 am-12:33 pm
1 stop8h 33m
San Diego
Sat 8/29
12:34 pm-9:40 pm
1 stop7h 06m
$425
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 7/30
11:00 am-6:50 pm
1 stop9h 50m
San Diego
Wed 8/5
6:19 am-5:33 pm
1 stop9h 14m
$426
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 7/2
4:17 pm-9:45 pm
1 stop7h 28m
San Diego
Mon 7/6
10:28 pm-10:27 am
1 stop9h 59m
$434
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Fri 10/9
4:10 pm-11:03 pm
1 stop8h 53m
San Diego
Mon 10/12
10:40 pm-8:17 am
1 stop7h 37m
$451
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Thu 11/12
11:25 am-5:25 pm
1 stop8h 00m
San Diego
Mon 11/16
7:05 am-6:15 pm
1 stop9h 10m
$457
Quickest round-trip
Panama CitySan Diego
ECP - SAN
ECPSAN
Panama City NW Florida Beaches
Mon 7/13
6:55 am-1:10 pm
2 stops8h 15m
San Diego
Fri 7/17
1:55 pm-9:45 pm
1 stop5h 50m
$462
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
ECP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Diego
What is the cheapest month to book a flight from Panama City, Florida to San Diego?
Currently, September is the cheapest month in which you can book a flight from Panama City, Florida to San Diego (average of $326). Flying from Panama City, Florida to San Diego in March is currently the most expensive (average of $575). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 7, 2026.
Read through reviews of airlines operating flights from Panama City to San Diego, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Panama City and San Diego flights
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Top 4 airlines flying from Panama City to San Diego
Discover the top 4 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$256 | Average$500 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$260 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$439 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$483 | FlexibilityNo cancel fee | On-time63% |