$155+ Cheap flights from Fort Myers to San Francisco (RSW - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — SFO
Aug 29 — Sep 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Fort Myers to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to San Francisco are usually found in September or August, booked 54 days in advance, depart on a Saturday or Wednesday and return on a Tuesday
Cheap flight deals from Fort Myers to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Fort Myers to San FranciscoExplore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from Fort Myers to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
RSW
- SFO
1 stop9h 15m
Southwest
Tue 8/2511:40 pm
SFO
- RSW
1 stop10h 00m
Southwest
Deal found 7/27![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:22 pm
RSW
- SFO
1 stop7h 51m
American Airlines
Fri 9/1111:03 pm
SFO
- RSW
1 stop8h 21m
American Airlines
Deal found 7/26![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:30 am
RSW
- SFO
1 stop9h 48m
American Airlines
Tue 9/811:28 pm
SFO
- RSW
1 stop7h 56m
American Airlines
Deal found 7/25![American Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:21 pm
RSW
- SFO
1 stop8h 07m
American Airlines
Tue 10/275:53 am
SFO
- RSW
1 stop7h 26m
American Airlines
Deal found 7/27![American Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Tue 9/810:30 pm
SFO
- RSW
1 stop9h 20m
Southwest
Deal found 7/25![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Tue 9/2911:50 am
SFO
- RSW
1 stop7h 25m
Southwest
Deal found 7/28![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:29 pm
RSW
- SFO
1 stop8h 29m
Delta
Tue 8/256:00 am
SFO
- RSW
1 stop9h 58m
Delta
Deal found 7/28![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:45 pm
RSW
- SFO
2 stops9h 30m
Southwest
Tue 11/36:15 am
SFO
- RSW
2 stops9h 20m
Southwest
Deal found 7/25![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Wed 9/3011:05 pm
SFO
- RSW
1 stop11h 05m
Southwest
Deal found 7/28![Southwest logo]()
$332
Best flights from Fort Myers to San FranciscoDiscover carefully curated flight deals from Fort Myers to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from Fort Myers to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Tue 9/810:30 pm
SFO
- RSW
1 stop9h 20m
Southwest
Deal found 7/25![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:30 am
RSW
- SFO
Nonstop6h 06m
United Airlines
Sat 11/711:30 pm
SFO
- RSW
1 stop10h 38m
United Airlines
Deal found 7/26![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:19 pm
RSW
- SFO
1 stop8h 38m
Delta
Sun 11/19:00 pm
SFO
- RSW
1 stop11h 37m
Delta
Deal found 7/28![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Tue 10/2711:40 pm
SFO
- RSW
2 stops11h 50m
Southwest
Deal found 7/27![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:40 pm
RSW
- SFO
1 stop9h 15m
Southwest
Thu 9/245:35 am
SFO
- RSW
2 stops12h 25m
Southwest
Deal found 7/29![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:46 am
RSW
- SFO
1 stop8h 09m
Delta
Tue 8/256:00 am
SFO
- RSW
1 stop7h 44m
Delta
Deal found 7/30![Delta logo]()
$404
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 am
RSW
- SFO
2 stops10h 55m
Southwest
Mon 8/3111:05 pm
SFO
- RSW
1 stop13h 20m
Southwest
Deal found 7/29![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Tue 9/298:40 am
SFO
- RSW
2 stops10h 35m
Southwest
Deal found 7/27![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:10 am
RSW
- SFO
1 stop8h 45m
Southwest
Wed 9/26:35 am
SFO
- RSW
2 stops10h 15m
Southwest
Deal found 7/28![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:50 am
RSW
- SFO
2 stops15h 25m
Southwest
Sat 10/315:10 am
SFO
- RSW
2 stops9h 50m
Southwest
Deal found 7/28![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:25 pm
RSW
- SFO
1 stop9h 25m
Southwest
Fri 9/1810:30 pm
SFO
- RSW
1 stop9h 40m
Southwest
Deal found 7/27![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:05 pm
RSW
- SFO
2 stops11h 30m
Southwest
Tue 9/85:50 am
SFO
- RSW
2 stops11h 05m
Southwest
Deal found 7/28![Southwest logo]()
$420
Last-minute flights from Fort Myers to San FranciscoDiscover last-minute flight deals from Fort Myers to San Francisco. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to San Francisco. Data last updated July 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:24 am
RSW
- SFO
2 stops32h 33m
Multiple Airlines
Tue 8/188:56 pm
SFO
- RSW
1 stop19h 18m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:30 am
RSW
- SFO
1 stop9h 54m
American Airlines
Sun 8/235:05 am
SFO
- RSW
1 stop10h 40m
American Airlines
Deal found 7/25![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:10 am
RSW
- SFO
1 stop7h 25m
Southwest
Mon 8/245:35 am
SFO
- RSW
2 stops12h 20m
Southwest
Deal found 7/26![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:29 pm
RSW
- SFO
1 stop8h 29m
Delta
Tue 8/256:00 am
SFO
- RSW
1 stop9h 58m
Delta
Deal found 7/28![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:05 am
RSW
- SFO
1 stop8h 55m
Southwest
Mon 8/2410:30 pm
SFO
- RSW
1 stop9h 20m
Southwest
Deal found 7/26![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:04 pm
RSW
- SFO
1 stop8h 58m
Delta
Wed 8/2610:35 pm
SFO
- RSW
1 stop9h 52m
Delta
Deal found 7/27![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:40 pm
RSW
- SFO
1 stop9h 15m
Southwest
Tue 8/2511:40 pm
SFO
- RSW
1 stop10h 00m
Southwest
Deal found 7/27![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:50 am
RSW
- SFO
2 stops10h 20m
Southwest
Fri 8/2810:30 pm
SFO
- RSW
1 stop9h 40m
Southwest
Deal found 7/28![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 am
RSW
- SFO
2 stops10h 55m
Southwest
Mon 8/3111:05 pm
SFO
- RSW
1 stop13h 20m
Southwest
Deal found 7/29![Southwest logo]()
$354
One-way flights from Fort Myers to San FranciscoSearch for one-way flight options from Fort Myers to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from Fort Myers to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:05 am
RSW
- SFO
1 stop8h 55m
Southwest
Deal found 7/28![Southwest logo]()
$155
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:15 am
RSW
- SFO
2 stops10h 20m
Southwest
Deal found 7/29![Southwest logo]()
$160
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:30 am
RSW
- SFO
2 stops11h 55m
Southwest
Deal found 7/28![Southwest logo]()
$161
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:30 pm
RSW
- SFO
1 stop9h 30m
Delta
Deal found 7/29![Delta logo]()
$165
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:35 pm
RSW
- SFO
2 stops11h 45m
Southwest
Deal found 7/28![Southwest logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:31 am
RSW
- SFO
2 stops32h 57m
Breeze Airways
Deal found 7/28![Breeze Airways logo]()
$170
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:05 am
RSW
- SFO
1 stop13h 35m
JetBlue
Deal found 7/26![JetBlue logo]()
$183
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:05 am
RSW
- SFO
1 stop13h 35m
JetBlue
Deal found 7/28![JetBlue logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:24 am
RSW
- SFO
2 stops32h 33m
Breeze Airways
Deal found 7/26![Breeze Airways logo]()
$186
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:50 pm
RSW
- SFO
1 stop11h 28m
JetBlue
Deal found 7/29![JetBlue logo]()
$188
Find flight deals from Fort Myers to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Southwest) |
One-way from | $155 (Southwest) |
Popular in | March |
Cheapest in | September |
Average price | $437 |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Fort Myers to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Tue 9/1
2:35 pm-11:20 pm
2 stops11h 45m
San Francisco
Tue 9/8
10:30 pm-10:50 am
1 stop9h 20m
$325
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Tue 9/22
2:35 pm-11:20 pm
2 stops11h 45m
San Francisco
Tue 10/27
11:40 pm-2:30 pm
2 stops11h 50m
$331
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Thu 9/10
3:40 pm-9:55 pm
1 stop9h 15m
San Francisco
Thu 9/24
5:35 am-9:00 pm
2 stops12h 25m
$349
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Wed 8/26
6:10 am-2:05 pm
2 stops10h 55m
San Francisco
Mon 8/31
11:05 pm-3:25 pm
1 stop13h 20m
$354
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Tue 9/22
2:35 pm-11:20 pm
2 stops11h 45m
San Francisco
Tue 9/29
8:40 am-10:15 pm
2 stops10h 35m
$359
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Sun 11/1
9:30 am-12:36 pm
Nonstop6h 06m
San Francisco
Sat 11/7
11:30 pm-1:08 pm
1 stop10h 38m
$368
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Mon 9/28
6:19 pm-11:57 pm
1 stop8h 38m
San Francisco
Sun 11/1
9:00 pm-11:37 am
1 stop11h 37m
$379
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Wed 8/26
7:10 am-12:55 pm
1 stop8h 45m
San Francisco
Wed 9/2
6:35 am-7:50 pm
2 stops10h 15m
$382
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Mon 9/28
6:50 am-7:15 pm
2 stops15h 25m
San Francisco
Sat 10/31
5:10 am-6:00 pm
2 stops9h 50m
$393
Fort MyersSan Francisco
RSW - SFO
RSWSFO
Fort Myers SW Florida Intl
Mon 9/14
5:25 pm-11:50 pm
1 stop9h 25m
San Francisco
Fri 9/18
10:30 pm-11:10 am
1 stop9h 40m
$403
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Fort Myers to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to San Francisco in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Fort Myers-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Fort Myers-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Fort Myers to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Fort Myers with our price prediction graph.
RSW-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Fort Myers to San Francisco
Prices
More
How far ahead should I book a flight from Fort Myers to San Francisco?
To ensure you get the cheapest price possible for a flight from Fort Myers to San Francisco, you should look to book at least 53 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Fort Myers to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Fort Myers to San Francisco (average of $348). Flying from Fort Myers to San Francisco in March is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Fort Myers to San Francisco?
Airfare is typical for this route at the moment.
Fort Myers to San Francisco flights typically cost between $308 and $403 in August.The cheapest round-trip price found within the last 5 days was $309 on Southwest (Aug 21-Aug 25).
What’s the top layover airport for flights from Fort Myers to San Francisco?
Share of 1-stop round-trip flights from Fort Myers to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Fort Myers to San Francisco on Cheapflights.
What’s the cheapest layover airport for flights from Fort Myers to San Francisco?
Average round-trip fare for 1-stop flights from Fort Myers to San Francisco, chosen by Cheapflights users in the past 12 months, with the same layover each way.
St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $362.
What’s the fastest layover option from Fort Myers to San Francisco?
Shortest average travel time for 1-stop one-way flights from Fort Myers to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via St. Louis (STL) have the shortest average one-way travel time for 1-stop routes: 9h 06m.
Which airport typically offers the quickest layover for flights from Fort Myers to San Francisco?
Average layover duration for 1-stop one-way flights from Fort Myers to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 24m.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 30, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Fort Myers to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
San Bruno
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Turlock
Vallejo
San Lorenzo
Davis
Vacaville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes
Alternative routes for Fort Myers to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Fort Myers to San Francisco by cabin class
Find flights from Fort Myers to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Fort Myers and San Francisco flights
Browse other Fort Myers and San Francisco flight options. Last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 30, 2026.
Top 4 airlines flying from Fort Myers to San Francisco
Discover the top 4 airlines that operate flights from Fort Myers to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$256 | Average$397 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$410 | FlexibilityNo cancel fee | On-time63% |