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$124+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to San Diego are usually found in September or August, booked 70 days in advance, depart on a Tuesday or Friday and return on a Tuesday

Cheap flight deals from Myrtle Beach to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$320
(Mytrip)

One-way from

$124
(Mytrip)

Popular in

July

Cheapest in

September

Average price

$526
Provider with most accurate pricing for Myrtle Beach Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Diego flights.
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From Myrtle Beach Intl to San Diego
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One-way flight from Myrtle Beach Intl to San Diego
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Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Myrtle Beach to San Diego

Cheapest flights from Myrtle Beach to San Diego
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:32 pmMYR - SAN
2 stops27h 31mSpirit Airlines
Sat 5/178:48 pmSAN - MYR
3 stops11h 11mSpirit Airlines
Deal found 4/28$320
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/152:29 pmMYR - SAN
2 stops30h 57mMultiple Airlines
Wed 6/186:15 amSAN - MYR
2 stops25h 18mMultiple Airlines
Deal found 4/28$329
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/243:59 pmMYR - SAN
1 stop8h 20mDelta
Mon 6/306:15 amSAN - MYR
1 stop7h 25mDelta
Deal found 4/28$360
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/155:03 pmMYR - SAN
1 stop9h 23mAmerican Airlines
Wed 6/189:13 pmSAN - MYR
1 stop8h 28mAmerican Airlines
Deal found 4/28$370
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/314:50 pmMYR - SAN
1 stop8h 54mUnited Airlines
Mon 8/47:27 pmSAN - MYR
2 stops11h 35mUnited Airlines
Deal found 4/28$438
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:25 amMYR - SAN
1 stop7h 15mSouthwest
Sat 5/178:15 amSAN - MYR
1 stop6h 40mSouthwest
Deal found 4/28$527
This Alaska Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/133:56 pmMYR - SAN
2 stops20h 56mAlaska Airlines
Wed 5/212:03 pmSAN - MYR
3 stops17h 16mAlaska Airlines
Deal found 4/28$762

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.

Fly from

Myrtle Beach

Fly to

San Diego

Route

Depart

Return

Price

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Wed 5/14

5:32 pm-6:03 pm

2 stops27h 31m

San Diego

Sat 5/17

8:48 pm-10:59 am

3 stops11h 11m

$320

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sun 6/15

2:29 pm-6:26 pm

2 stops30h 57m

San Diego

Wed 6/18

6:15 am-10:33 am

2 stops25h 18m

$329

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 6/24

3:59 pm-9:19 pm

1 stop8h 20m

San Diego

Mon 6/30

6:15 am-4:40 pm

1 stop7h 25m

$360

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sun 6/15

5:03 pm-11:26 pm

1 stop9h 23m

San Diego

Wed 6/18

9:13 pm-8:41 am

1 stop8h 28m

$370

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 7/31

4:50 pm-10:44 pm

1 stop8h 54m

San Diego

Mon 8/4

7:27 pm-10:02 am

2 stops11h 35m

$438

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Wed 5/14

6:25 am-10:40 am

1 stop7h 15m

San Diego

Sat 5/17

8:15 am-5:55 pm

1 stop6h 40m

$527

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 5/13

3:56 pm-9:52 am

2 stops20h 56m

San Diego

Wed 5/21

2:03 pm-10:19 am

3 stops17h 16m

$762

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Fri 5/30

1:45 pm-7:53 pm

2 stops33h 08m

$124

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 5/27

11:33 am-6:08 pm

1 stop9h 35m

$157

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Fri 5/30

5:00 am-10:59 am

1 stop8h 59m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 13 results
1
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Compare providers for flights from Myrtle Beach to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Diego in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Diego

How far ahead should I book a flight from Myrtle Beach to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to San Diego. Price data was last updated on April 25, 2025.

The best time to book flights from Myrtle Beach to San Diego is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Myrtle Beach to San Diego?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SAN?

Find hourly flight availability from Myrtle Beach to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Myrtle Beach to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 13% versus a flight in the afternoon.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 29, 2025.
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,961 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,292 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,929 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to San Diego round-trip?

    Cheapflights users have booked flights from Myrtle Beach to San Diego round-trip from $320. Other airlines that can offer you cheap pricing are Delta, from $360, and American Airlines, from $370. Spirit Airlines is currently priced 31% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to San Diego one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $124. Delta flights start at $157 while deals on American Airlines start at $179 one-way.

  • Can I find deals for flights from Myrtle Beach to San Diego that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Diego.

  • Can I find deals for business class flights from Myrtle Beach to San Diego?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado

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Top 3 airlines flying from Myrtle Beach to San Diego

Discover the top 3 airlines that operate flights from Myrtle Beach to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$445FlexibilityNo cancel feeOn-time71%
DeltaCheapest$346Average$448FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$437Average$482FlexibilityNo cancel feeOn-time63%

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