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$131+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to San Diego are usually found in August or May, booked 71 days in advance, depart on a Tuesday or Friday and return on a Tuesday

Cheap flight deals from Myrtle Beach to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$257
(Mytrip)

One-way from

$131
(Mytrip)

Popular in

June

Cheapest in

August

Average price

$596
From Myrtle Beach Intl to San Diego
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One-way flight from Myrtle Beach Intl to San Diego
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Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Myrtle Beach to San Diego

Cheapest flights from Myrtle Beach to San Diego
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:09 amMYR - SAN
2 stops28h 04mSpirit Airlines
Sun 6/297:31 pmSAN - MYR
2 stops18h 05mSpirit Airlines
Deal found 6/10$257
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/712:11 pmMYR - SAN
2 stops24h 44mMultiple Airlines
Thu 8/2111:40 amSAN - MYR
2 stops32h 43mMultiple Airlines
Deal found 6/11$279
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:50 pmMYR - SAN
1 stop6h 31mDelta
Mon 8/182:00 pmSAN - MYR
1 stop6h 49mDelta
Deal found 6/10$297
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:06 pmMYR - SAN
1 stop9h 17mAmerican Airlines
Mon 8/189:45 amSAN - MYR
2 stops10h 26mAmerican Airlines
Deal found 6/12$302
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:00 pmMYR - SAN
1 stop7h 45mSouthwest
Mon 8/189:10 pmSAN - MYR
1 stop9h 45mSouthwest
Deal found 6/10$362
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/84:50 pmMYR - SAN
2 stops9h 54mUnited Airlines
Mon 8/189:40 pmSAN - MYR
1 stop9h 50mUnited Airlines
Deal found 6/11$367
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3111:00 amMYR - SAN
2 stops15h 53mAlaska Airlines
Sun 9/710:59 amSAN - MYR
3 stops20h 18mAlaska Airlines
Deal found 6/10$655

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.

Fly from

Myrtle Beach

Fly to

San Diego

Route

Depart

Return

Price

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Wed 6/25

6:09 am-7:13 am

2 stops28h 04m

San Diego

Sun 6/29

7:31 pm-4:36 pm

2 stops18h 05m

$257

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 8/7

12:11 pm-9:55 am

2 stops24h 44m

San Diego

Thu 8/21

11:40 am-11:23 pm

2 stops32h 43m

$279

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 8/7

7:50 pm-11:21 pm

1 stop6h 31m

San Diego

Mon 8/18

2:00 pm-11:49 pm

1 stop6h 49m

$297

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 8/7

5:06 pm-11:23 pm

1 stop9h 17m

San Diego

Mon 8/18

9:45 am-11:11 pm

2 stops10h 26m

$302

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Fri 8/8

6:00 pm-10:45 pm

1 stop7h 45m

San Diego

Mon 8/18

9:10 pm-9:55 am

1 stop9h 45m

$362

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Fri 8/8

4:50 pm-11:44 pm

2 stops9h 54m

San Diego

Mon 8/18

9:40 pm-10:30 am

1 stop9h 50m

$367

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sun 8/31

11:00 am-11:53 pm

2 stops15h 53m

San Diego

Sun 9/7

10:59 am-10:17 am

3 stops20h 18m

$655

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Mon 6/30

11:17 am-6:26 pm

2 stops34h 09m

$131

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sun 6/29

12:09 pm-7:13 am

2 stops22h 04m

$142

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Wed 10/29

5:33 am-9:14 am

1 stop6h 41m

$149

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 14 results
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Best time to book a flight from Myrtle Beach to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Diego

How far ahead should I book a flight from Myrtle Beach to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to San Diego. Price data was last updated on June 9, 2025.

The best time to book flights from Myrtle Beach to San Diego is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Myrtle Beach to San Diego?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SAN?

Find hourly flight availability from Myrtle Beach to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Myrtle Beach to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 13% versus a flight in the afternoon.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 12, 2025.
To help decide which airline to fly from Myrtle Beach to San Diego, see what other customers have to say about Alaska Airlines, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to San Diego round-trip?

    Cheapflights users have booked flights from Myrtle Beach to San Diego round-trip from $257. Other airlines that can offer you cheap pricing are Delta, from $297, and American Airlines, from $302. Spirit Airlines is currently priced 43% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to San Diego one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $131. American Airlines flights start at $149 while deals on United Airlines start at $204 one-way.

  • Can I find deals for flights from Myrtle Beach to San Diego that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Diego.

  • Can I find deals for business class flights from Myrtle Beach to San Diego?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Imperial Beach
La Mesa
Alpine
Lemon Grove
Poway
Santee
Coronado

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Top 3 airlines flying from Myrtle Beach to San Diego

Discover the top 3 airlines that operate flights from Myrtle Beach to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$433FlexibilityNo cancel feeOn-time71%
DeltaCheapest$331Average$436FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$437Average$492FlexibilityNo cancel feeOn-time63%

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