San Diego

$122+ Cheap flights from Lexington to San Diego (LEX - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — SAN
Oct 11 — Oct 181
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Cheapflights Tip: The best prices from Lexington Blue Grass to San Diego are usually found in August or July, booked 84 days in advance, depart on a Wednesday or Saturday and return on a Wednesday

Cheap flight deals from Lexington to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$217
(American Airlines)

One-way from

$122
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$358
From Lexington Blue Grass to San Diego
One-way flight from Lexington Blue Grass to San Diego
Highest demand for flights based on searches. 7% potential increase in price ($33 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Lexington to San Diego

Cheapest flights from Lexington to San Diego
Explore the most affordable flight options available from Lexington to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:29 amLEX - SAN
1 stop7h 27mAmerican Airlines
Sat 11/11:14 pmSAN - LEX
1 stop7h 07mAmerican Airlines
Deal found 9/9$218
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:29 amLEX - SAN
1 stop7h 27mAmerican Airlines
Mon 11/310:23 pmSAN - LEX
1 stop8h 53mAmerican Airlines
Deal found 9/10$253
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:22 pmLEX - SAN
1 stop6h 58mAmerican Airlines
Wed 11/1911:41 amSAN - LEX
1 stop8h 57mAmerican Airlines
Deal found 9/10$258
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:05 pmLEX - SAN
1 stop28h 43mMultiple Airlines
Sun 11/168:30 amSAN - LEX
1 stop9h 45mMultiple Airlines
Deal found 9/9$276
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:57 pmLEX - SAN
1 stop8h 17mDelta
Mon 11/310:20 pmSAN - LEX
1 stop8h 25mDelta
Deal found 9/11$283
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/291:59 pmLEX - SAN
1 stop7h 51mUnited Airlines
Mon 11/311:02 amSAN - LEX
2 stops9h 42mUnited Airlines
Deal found 9/10$288
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:22 pmLEX - SAN
1 stop8h 18mAmerican Airlines
Mon 11/310:23 pmSAN - LEX
1 stop8h 53mAmerican Airlines
Deal found 9/9$289
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/243:36 pmLEX - SAN
1 stop7h 14mAmerican Airlines
Fri 10/3110:31 pmSAN - LEX
1 stop9h 02mAmerican Airlines
Deal found 9/10$294
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:42 pmLEX - SAN
1 stop6h 45mDelta
Wed 10/2910:20 pmSAN - LEX
1 stop8h 25mDelta
Deal found 9/11$297
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:00 amLEX - SAN
1 stop7h 40mUnited Airlines
Tue 9/162:11 pmSAN - LEX
1 stop6h 26mUnited Airlines
Deal found 9/10$299
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:42 pmLEX - SAN
1 stop7h 44mDelta
Mon 11/310:30 pmSAN - LEX
1 stop7h 50mDelta
Deal found 9/11$303

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Lexington to San Diego that are best for you.

Fly from

Lexington

Fly to

San Diego

Route

Depart

Return

Price

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Thu 11/13

10:05 pm-11:48 pm

1 stop28h 43m

San Diego

Sun 11/16

8:30 am-9:15 pm

1 stop9h 45m

$276

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Sat 2/28

3:45 pm-8:56 pm

1 stop8h 11m

San Diego

Tue 3/3

10:40 pm-9:25 am

1 stop7h 45m

$277

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Wed 10/29

5:57 pm-11:14 pm

1 stop8h 17m

San Diego

Mon 11/3

10:30 pm-9:20 am

1 stop7h 50m

$283

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Wed 10/29

1:59 pm-6:50 pm

1 stop7h 51m

San Diego

Mon 11/3

11:02 am-11:44 pm

2 stops9h 42m

$288

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Thu 10/30

6:22 pm-11:40 pm

1 stop8h 18m

San Diego

Mon 11/3

10:23 pm-10:16 am

1 stop8h 53m

$289

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Tue 9/23

3:42 pm-7:27 pm

1 stop6h 45m

San Diego

Wed 10/29

10:20 pm-9:45 am

1 stop8h 25m

$297

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Tue 9/23

3:42 pm-7:27 pm

1 stop6h 45m

San Diego

Thu 10/30

10:20 pm-9:45 am

1 stop8h 25m

$303

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Wed 9/24

5:48 pm-9:47 pm

1 stop6h 59m

San Diego

Mon 11/3

10:30 pm-9:20 am

1 stop7h 50m

$303

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Thu 9/25

5:48 pm-9:47 pm

1 stop6h 59m

San Diego

Tue 10/28

10:30 pm-9:20 am

1 stop7h 50m

$308

LexingtonSan Diego

LEX - SAN

LEXSAN

Lexington Blue Grass

Sat 11/15

6:00 am-11:45 am

1 stop8h 45m

San Diego

Wed 11/19

10:56 am-10:37 am

2 stops20h 41m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 21 results
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Best time to book a flight from Lexington to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to San Diego

How far ahead should I book a flight from Lexington to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Lexington to San Diego. Price data was last updated on August 29, 2025.

The best time to book flights from Lexington to San Diego is 84 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Lexington to San Diego?

Currently, August is the cheapest month in which you can book a flight from Lexington to San Diego (average of $286). Flying from Lexington to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to SAN?

Find hourly flight availability from Lexington to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Lexington to San Diego in the afternoon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Lexington to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Lexington to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Lexington to San Diego flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Lexington to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good
8.0
Very good

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Lexington to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Lexington to San Diego?

    A quick flight from Lexington to San Diego can take about 7h 51m. Delta provides one of the quickest options available for as low as $288. The distance between Lexington and San Diego is about 1861 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Lexington to San Diego round-trip?

    According to our current data, American Airlines ($234), United Airlines ($276), and Delta ($282) offers the cheapest pricing from Lexington to San Diego. American Airlines is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Lexington to San Diego that include hotel bookings?

    Yes. In addition to deals on Lexington to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to San Diego.

  • Can I find deals for business class flights from Lexington to San Diego?

    Yes. Cheapflights offers flight deals from Lexington to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Lexington to San Diego (average of $286). Flying from Lexington to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

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Alternative routes for Lexington to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Lexington to San Diego

Discover the top 3 airlines that operate flights from Lexington to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$234Average$399FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$282Average$378FlexibilityNo cancel feeOn-timeN/A

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