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$72+ Cheap flights from Missouri to Pittsburgh (PIT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PIT
Feb 15 — Feb 221
Sun 2/15
Sun 2/22
1 adult, Economy
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Cheap flight deals from Missouri to Pittsburgh

Keep the following information in mind while searching for Missouri to Pittsburgh flight deals. Data was last updated January 16, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$175
(American Airlines)

One-way from

$72
(Trip.com)

Popular in

February

Cheapest in

December

Average price

$304

Good round-trip deal

$349 or less
Provider with most accurate pricing for Lambert-St Louis-Pittsburgh flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Pittsburgh flights.
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From Missouri to Pittsburgh
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One-way flight from Missouri to Pittsburgh
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Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Missouri to Pittsburgh.
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Find flight deals from Missouri to Pittsburgh

Cheapest flights from Missouri to Pittsburgh
Explore the most affordable flight options available from Missouri to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2026.

This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/77:00 am
STL
-
PIT
1 stop6h 41m
American Airlines
Tue 2/105:00 pm
PIT
-
STL
1 stop5h 15m
American Airlines
Deal found 1/15$175
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:40 am
STL
-
PIT
1 stop5h 42m
Delta
Tue 4/282:02 pm
PIT
-
STL
1 stop3h 40m
Delta
Deal found 1/14$184
This Priceline deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2311:26 am
MCI
-
PIT
1 stop11h 33m
Spirit Airlines
Tue 2/245:45 am
PIT
-
MCI
1 stop10h 44m
Spirit Airlines
Deal found 1/15$199
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:40 pm
STL
-
PIT
Nonstop1h 35m
Southwest
Tue 4/286:05 am
PIT
-
STL
1 stop6h 20m
Southwest
Deal found 1/14$207
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
-
PIT
2 stops12h 04m
Multiple Airlines
Tue 2/245:45 am
PIT
-
MCI
1 stop10h 44m
Multiple Airlines
Deal found 1/14$235
This Southwest deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:30 am
STL
-
PIT
2 stops7h 50m
Southwest
Tue 2/1012:15 pm
PIT
-
STL
1 stop3h 45m
Southwest
Deal found 1/15$236
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2311:26 am
MCI
-
PIT
1 stop11h 33m
Spirit Airlines
Thu 2/269:09 pm
PIT
-
MCI
1 stop14h 21m
Spirit Airlines
Deal found 1/15$246
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
-
PIT
2 stops28h 44m
Multiple Airlines
Thu 2/269:09 pm
PIT
-
MCI
1 stop14h 21m
Multiple Airlines
Deal found 1/15$248
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1211:26 am
MCI
-
PIT
1 stop7h 48m
Spirit Airlines
Thu 2/199:09 pm
PIT
-
MCI
1 stop14h 21m
Spirit Airlines
Deal found 1/15$251
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:00 am
STL
-
PIT
1 stop6h 41m
American Airlines
Sun 2/159:13 am
PIT
-
STL
1 stop5h 30m
American Airlines
Deal found 1/15$253
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/111:26 am
MCI
-
PIT
1 stop21h 14m
Multiple Airlines
Sat 2/215:45 pm
PIT
-
MCI
2 stops16h 44m
Multiple Airlines
Deal found 1/13$253
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/297:00 am
MCI
-
PIT
3 stops25h 40m
Spirit Airlines
Sun 2/16:15 pm
PIT
-
MCI
1 stop17h 16m
Spirit Airlines
Deal found 1/15$256

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Missouri to Pittsburgh that are best for you.

Fly from

Missouri

Fly to

Pittsburgh

Route

Depart

Return

Price

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Sat 2/7

7:00 am-2:41 pm

1 stop6h 41m

Pittsburgh

Tue 2/10

5:00 pm-9:15 pm

1 stop5h 15m

$175

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 4/23

9:40 am-4:22 pm

1 stop5h 42m

Pittsburgh

Tue 4/28

2:02 pm-4:42 pm

1 stop3h 40m

$184

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Mon 2/23

11:26 am-11:59 pm

1 stop11h 33m

Pittsburgh

Tue 2/24

5:45 am-3:29 pm

1 stop10h 44m

$199

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 4/23

7:40 pm-10:15 pm

Nonstop1h 35m

Pittsburgh

Tue 4/28

6:05 am-11:25 am

1 stop6h 20m

$207

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Mon 2/23

10:55 am-11:59 pm

2 stops12h 04m

Pittsburgh

Tue 2/24

5:45 am-3:29 pm

1 stop10h 44m

$235

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Sat 2/7

10:30 am-7:20 pm

2 stops7h 50m

Pittsburgh

Tue 2/10

12:15 pm-3:00 pm

1 stop3h 45m

$236

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Mon 2/23

11:26 am-11:59 pm

1 stop11h 33m

Pittsburgh

Thu 2/26

9:09 pm-10:30 am

1 stop14h 21m

$246

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Mon 2/23

10:55 am-4:39 pm

2 stops28h 44m

Pittsburgh

Thu 2/26

9:09 pm-10:30 am

1 stop14h 21m

$248

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Sun 2/1

11:26 am-9:40 am

1 stop21h 14m

Pittsburgh

Sat 2/21

5:45 pm-9:29 am

2 stops16h 44m

$253

Kansas CityPittsburgh

MCI - PIT

MCIPIT

Kansas City

Sun 2/1

11:26 am-9:40 am

1 stop21h 14m

Pittsburgh

Sat 2/21

6:00 am-10:30 am

1 stop29h 30m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 44 results
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Best time to book a flight from Missouri to Pittsburgh

Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Pittsburgh

What is the cheapest month to book a flight from Missouri to Pittsburgh?

Currently, April is the cheapest month in which you can book a flight from Missouri to Pittsburgh (average of $135). Flying from Missouri to Pittsburgh in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PIT?

Find hourly flight availability from Missouri to Pittsburgh. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 16, 2026.

It’s optimal to fly from Missouri to Pittsburgh in the afternoon. By choosing this option you can save up to 42% on the cost of your flight, compared to a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Pittsburgh from Missouri?

    Pittsburgh (PIT), located 13.5 mi from the city center, is the airport you fly into when you book flights from Missouri to Pittsburgh.

  • How popular is this Missouri to Pittsburgh flight route?

    The Missouri to Pittsburgh flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Pittsburgh?

    American Airlines, Delta, and Spirit Airlines can get you from Missouri to Pittsburgh in just under 5h 42m. Your travel time can differ by up to 5h 51m. There are 552 mi between Missouri and Pittsburgh. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Pittsburgh one-way?

    $118 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $125 and $129, respectively.

  • What are the most popular routes from Missouri to Pittsburgh?

    While some choose either Kansas City - Pittsburgh or Columbia Regional - Pittsburgh, Lambert-St Louis - Pittsburgh is the most popular route from Missouri to Pittsburgh.

  • What are the cheapest flights from Missouri to Pittsburgh?

    Looking at all options, your cheapest flight can be booked for $349. While the most popular route (Lambert-St Louis - Pittsburgh) can be booked for $184 on average, our data indicates $369 when flying from Missouri to Pittsburgh.

  • Can I find deals for flights from Missouri to Pittsburgh that include hotel bookings?

    Yes. In addition to deals on Missouri to Pittsburgh flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Pittsburgh?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Pittsburgh.

  • Can I find deals for business class flights from Missouri to Pittsburgh?

    Yes. Cheapflights offers flight deals from Missouri to Pittsburgh by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Pittsburgh?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Pittsburgh (average of $135). Flying from Missouri to Pittsburgh in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Pittsburgh?

Book flights to Pittsburgh if you plan to visit one of these locations
Mars
Steubenville
Washington
Monroeville
Wexford
Belle Vernon

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Alternative routes for Missouri to Pittsburgh

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Pittsburgh

Discover the top 4 airlines that operate flights from Missouri to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$108Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$419FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$241Average$370FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$248Average$402FlexibilityNo cancel feeOn-time69%

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