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$69+ Cheap flights from Missouri to Pittsburgh (PIT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PIT
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Missouri to Pittsburgh

Cheapest flights from Missouri to Pittsburgh
Explore the most affordable flight options available from Missouri to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amSTL - PIT
1 stop6h 09mAmerican Airlines
Mon 12/86:39 pmPIT - STL
1 stop5h 59mAmerican Airlines
Deal found 11/5$159
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amSTL - PIT
1 stop3h 55mDelta
Wed 12/175:26 pmPIT - STL
1 stop5h 31mDelta
Deal found 11/5$177
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:08 amSTL - PIT
1 stop7h 01mAmerican Airlines
Thu 1/18:15 amPIT - STL
1 stop9h 08mAmerican Airlines
Deal found 11/3$183
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:15 amSTL - PIT
1 stop8h 59mAmerican Airlines
Sun 12/76:30 amPIT - STL
1 stop9h 20mAmerican Airlines
Deal found 11/5$191
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:13 amSTL - PIT
1 stop4h 52mAmerican Airlines
Sat 1/1011:17 amPIT - STL
1 stop4h 47mAmerican Airlines
Deal found 11/6$194
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amSTL - PIT
1 stop3h 55mDelta
Tue 12/912:00 pmPIT - STL
1 stop5h 06mDelta
Deal found 11/4$199
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:39 amSTL - PIT
1 stop4h 27mDelta
Tue 12/910:17 amPIT - STL
1 stop6h 49mDelta
Deal found 11/4$203
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:56 pmSTL - PIT
1 stop5h 09mAmerican Airlines
Tue 12/96:30 pmPIT - STL
1 stop5h 36mAmerican Airlines
Deal found 11/3$214
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:05 pmSTL - PIT
1 stop4h 48mAmerican Airlines
Thu 11/278:15 amPIT - STL
1 stop9h 10mAmerican Airlines
Deal found 11/4$216
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:25 amSTL - PIT
Nonstop1h 35mSouthwest
Tue 12/166:45 pmPIT - STL
1 stop4h 35mSouthwest
Deal found 11/4$218
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:40 amSTL - PIT
1 stop6h 09mDelta
Mon 12/812:01 pmPIT - STL
1 stop5h 05mDelta
Deal found 11/4$221
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - PIT
1 stop6h 41mMultiple Airlines
Sun 12/73:10 pmPIT - MCI
2 stops21h 41mMultiple Airlines
Deal found 11/5$269

Cheap flight deals from Missouri to Pittsburgh

Keep the following information in mind while searching for Missouri to Pittsburgh flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$159
(American Airlines)

One-way from

$69
(Southwest)

Popular in

October

Cheapest in

May

Average price

$418

Good round-trip deal

$263 or less

Good one-way deal

$169 or less
Provider with most accurate pricing for Lambert-St Louis-Pittsburgh flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Pittsburgh flights.
Search Deals
From Missouri to Pittsburgh
Search Deals
One-way flight from Missouri to Pittsburgh
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Missouri to Pittsburgh.
Search Deals
Price to beat on a one-way flight from Missouri to Pittsburgh.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Pittsburgh that are best for you.

Fly from

Missouri

Fly to

Pittsburgh

Route

Depart

Return

Price

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Fri 12/5

6:00 am-1:09 pm

1 stop6h 09m

Pittsburgh

Mon 12/8

6:39 pm-11:38 pm

1 stop5h 59m

$159

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Sat 12/13

7:55 am-12:40 pm

1 stop3h 45m

Pittsburgh

Tue 12/16

6:45 pm-10:20 pm

1 stop4h 35m

$183

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 12/25

6:00 am-5:09 pm

1 stop10h 09m

Pittsburgh

Thu 1/1

7:24 am-4:23 pm

1 stop9h 59m

$183

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Tue 12/9

8:13 am-2:05 pm

1 stop4h 52m

Pittsburgh

Sat 1/10

11:17 am-3:04 pm

1 stop4h 47m

$194

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 12/4

6:00 am-10:55 am

1 stop3h 55m

Pittsburgh

Tue 12/9

12:00 pm-4:06 pm

1 stop5h 06m

$199

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Sat 1/17

11:05 am-9:12 pm

1 stop9h 07m

Pittsburgh

Mon 1/19

1:25 pm-5:23 pm

1 stop4h 58m

$202

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Fri 1/16

11:05 am-9:00 pm

1 stop8h 55m

Pittsburgh

Mon 1/19

3:25 pm-8:32 pm

1 stop6h 07m

$206

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 12/4

11:40 am-6:49 pm

1 stop6h 09m

Pittsburgh

Mon 12/8

12:01 pm-4:06 pm

1 stop5h 05m

$221

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Sat 12/6

1:35 pm-7:25 pm

1 stop4h 50m

Pittsburgh

Mon 12/8

7:45 pm-11:42 pm

1 stop4h 57m

$225

St. LouisPittsburgh

STL - PIT

STLPIT

Lambert-St Louis

Thu 12/4

2:47 pm-12:41 am

1 stop8h 54m

Pittsburgh

Sun 12/7

3:10 pm-9:52 am

2 stops19h 42m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 50 results
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Best time to book a flight from Missouri to Pittsburgh

Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Pittsburgh

What is the cheapest month to book a flight from Missouri to Pittsburgh?

Currently, April is the cheapest month in which you can book a flight from Missouri to Pittsburgh (average of $135). Flying from Missouri to Pittsburgh in July is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PIT?

Find hourly flight availability from Missouri to Pittsburgh. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s optimal to fly from Missouri to Pittsburgh at noon. By choosing this option you can save up to 22% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Missouri to Pittsburgh?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Pittsburgh from Missouri?

    Pittsburgh (PIT), located 13.5 mi from the city center, is the airport you fly into when you book flights from Missouri to Pittsburgh.

  • How long is the flight from Missouri to Pittsburgh?

    American Airlines, Southwest, and Delta can get you from Missouri to Pittsburgh in just under 3h 45m. Your travel time can differ by up to 2h 24m. There are 552 mi between Missouri and Pittsburgh. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Pittsburgh?

    While some choose either Kansas City - Pittsburgh or Springfield-Branson - Pittsburgh, Lambert-St Louis - Pittsburgh is the most popular route from Missouri to Pittsburgh.

  • What are the cheapest flights from Missouri to Pittsburgh?

    Looking at all options, your cheapest flight can be booked for $149. While the most popular route (Lambert-St Louis - Pittsburgh) can be booked for $177 on average, our data indicates $321 when flying from Missouri to Pittsburgh.

  • Can I find deals for flights from Missouri to Pittsburgh that include hotel bookings?

    Yes. In addition to deals on Missouri to Pittsburgh flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Pittsburgh?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Pittsburgh.

  • Can I find deals for business class flights from Missouri to Pittsburgh?

    Yes. Cheapflights offers flight deals from Missouri to Pittsburgh by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Pittsburgh?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Pittsburgh (average of $135). Flying from Missouri to Pittsburgh in July is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Pittsburgh?

Book flights to Pittsburgh if you plan to visit one of these locations
Mars
Steubenville
Monroeville
Washington
Wexford
Belle Vernon

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Alternative routes for Missouri to Pittsburgh

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Top 4 airlines flying from Missouri to Pittsburgh

Discover the top 4 airlines that operate flights from Missouri to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$234Average$403FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$362FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$248Average$376FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$248Average$426FlexibilityNo cancel feeOn-time69%

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