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$221+ Cheap flights from Spartanburg, SC to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
jun. 28 — jul. 51
sáb. 6/28
sáb. 7/5
1 adult, Economy
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Cheap flight deals from Spartanburg to Panama

Keep the following information in mind while searching for Spartanburg to Panama flight deals. Data was last updated junio 23, 2025.

Round-trip from

$460
(Kiwi.com)

One-way from

$221
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$569
From Spartanburg to Panama
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One-way flight from Spartanburg to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($111 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Spartanburg to Panama

Cheapest flights from Spartanburg to Panama
Explore the most affordable flight options available from Spartanburg to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/179:12 amCLT - PTY
1 stop11h 17mMultiple Airlines
dom. 8/249:33 pmPTY - CLT
1 stop14h 05mMultiple Airlines
Deal found 6/23$460
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/2810:25 pmCLT - PTY
1 stop17h 05mAmerican Airlines
mar. 9/23:30 pmPTY - CLT
1 stop16h 43mAmerican Airlines
Deal found 6/21$467
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/305:35 amCLT - PTY
1 stop8h 15mDelta
jue. 9/42:05 pmPTY - CLT
1 stop8h 46mDelta
Deal found 6/23$487
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/237:00 amCLT - PTY
1 stop8h 14mUnited Airlines
dom. 10/263:41 pmPTY - CLT
1 stop29h 18mUnited Airlines
Deal found 6/23$497

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 23, 2025.
Use the filters below to find and compare flights from Spartanburg to Panama that are best for you.

Fly from

Spartanburg

Fly to

Panama

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

dom. 8/17

9:12 am-7:29 pm

1 stop11h 17m

Panama City Tocumen Intl

dom. 8/24

9:33 pm-12:38 pm

1 stop14h 05m

$460

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 8/28

10:25 pm-2:30 pm

1 stop17h 05m

Panama City Tocumen Intl

mar. 9/2

3:30 pm-9:13 am

1 stop16h 43m

$467

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

sáb. 8/30

5:35 am-12:50 pm

1 stop8h 15m

Panama City Tocumen Intl

jue. 9/4

2:05 pm-11:51 pm

1 stop8h 46m

$487

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 7/24

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

lun. 7/28

3:30 pm-11:00 am

1 stop18h 30m

$507

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

mar. 9/9

10:25 am-12:10 am

2 stops14h 45m

Panama City Tocumen Intl

lun. 9/15

3:25 am-6:53 pm

2 stops14h 28m

$1,400

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

lun. 7/28

6:00 am-1:31 pm

1 stop8h 31m

Panama City Tocumen Intl

jue. 7/31

10:29 pm-9:48 am

1 stop10h 19m

$1,616

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 7/31

10:29 pm-12:54 pm

1 stop15h 25m

$221

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

sáb. 7/19

8:48 am-2:40 pm

2 stops30h 52m

$236

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

dom. 7/20

5:00 pm-2:14 pm

1 stop22h 14m

$237

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

sáb. 7/19

9:30 am-7:03 pm

1 stop10h 33m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Best time to book a flight from Spartanburg to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Panama

What is the cheapest month to book a flight from Spartanburg to Panama?

Currently, October is the cheapest month in which you can book a flight from Spartanburg to Panama (average of $478). Flying from Spartanburg to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to PA?

Find hourly flight availability from Spartanburg to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Spartanburg to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated junio 23, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines and United Airlines from Spartanburg to Panama to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,965 reviews
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,460 reviews
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,831 reviews
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,352 reviews
Delta
8.0
Very good
7,965 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Spartanburg to Panama one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $221. United Airlines flights start at $237 while deals on Delta start at $261 one-way.

  • Can I find deals for flights from Spartanburg to Panama that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Panama.

  • Can I find deals for business class flights from Spartanburg to Panama?

    Yes. Cheapflights offers flight deals from Spartanburg to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Panama?

    Currently, October is the cheapest month in which you can book a flight from Spartanburg to Panama (average of $478). Flying from Spartanburg to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Spartanburg to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Columbia to San Pedro Sula flights
Myrtle Beach to Panama City flights
Myrtle Beach to Guatemala City flights
Greenville to San Pedro Sula flights
Greenville to San Salvador flights
Augusta to Philip S.W.Goldson flights
Columbia to Liberia flights
Hilton Head Island to Liberia flights
Hilton Head Island to San José flights
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Top 3 airlines flying from Spartanburg to Panama

Discover the top 3 airlines that operate flights from Spartanburg to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$285Average$461FlexibilityNo cancel feeOn-time69%
DeltaCheapest$341Average$562FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$352Average$575FlexibilityNo cancel feeOn-time71%

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