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$174+ Cheap flights from Ohio to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Ohio to Panama

Keep the following information in mind while searching for Ohio to Panama flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$414
(United Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$570
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
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From Ohio to Panama
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One-way flight from Ohio to Panama
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Highest demand for flights based on searches. 8% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Ohio to Panama

Cheapest flights from Ohio to Panama
Explore the most affordable flight options available from Ohio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:25 pmCMH - PTY
2 stops22h 20mUnited Airlines
Sun 12/214:41 pmPTY - CMH
1 stop30h 48mUnited Airlines
Deal found 10/30$445
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/284:23 pmDTW - PTY
2 stops15h 43mMultiple Airlines
Fri 12/58:25 amPTY - DTW
1 stop9h 44mMultiple Airlines
Deal found 10/29$490
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:04 pmCVG - PTY
1 stop13h 36mMultiple Airlines
Thu 12/118:25 amPTY - CVG
1 stop9h 21mMultiple Airlines
Deal found 10/30$505
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amCVG - PTY
1 stop8h 15mUnited Airlines
Wed 12/1711:35 amPTY - CVG
1 stop12h 09mUnited Airlines
Deal found 10/28$510
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:30 amCVG - PTY
1 stop13h 08mUnited Airlines
Thu 12/184:41 pmPTY - CVG
2 stops20h 36mUnited Airlines
Deal found 10/27$514
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:47 amDTW - PTY
3 stops32h 08mMultiple Airlines
Sat 12/1311:25 amPTY - DTW
2 stops12h 54mMultiple Airlines
Deal found 10/28$515
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:05 pmCVG - PTY
1 stop21h 37mAmerican Airlines
Thu 12/184:55 pmPTY - CVG
1 stop8h 04mAmerican Airlines
Deal found 10/27$521
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:45 pmCAK - PTY
2 stops23h 22mUnited Airlines
Fri 12/1211:35 amPTY - CAK
2 stops25h 33mUnited Airlines
Deal found 10/28$522
This Avianca Connect deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:20 amDTW - PTY
2 stops19h 20mMultiple Airlines
Tue 12/22:55 amPTY - DTW
2 stops14h 38mMultiple Airlines
Deal found 10/29$527
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:30 amCVG - PTY
1 stop10h 37mUnited Airlines
Wed 12/1010:00 amPTY - CVG
1 stop11h 06mUnited Airlines
Deal found 10/30$530
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:00 amPIT - PTY
1 stop13h 38mUnited Airlines
Tue 12/98:55 amPTY - PIT
1 stop13h 19mUnited Airlines
Deal found 10/29$530
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3010:00 pmCVG - PTY
2 stops16h 45mUnited Airlines
Mon 12/811:55 pmPTY - CVG
2 stops13h 21mUnited Airlines
Deal found 10/30$534

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Ohio to Panama that are best for you.

Fly from

Ohio

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Wed 1/28

10:00 am-7:31 pm

1 stop9h 31m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/5

7:55 pm-12:55 pm

1 stop18h 00m

Panama City Tocumen Intl

Tue 4/7

2:20 pm-9:01 am

1 stop17h 41m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

8:25 pm-12:10 pm

2 stops16h 45m

Panama City Tocumen Intl

Tue 4/7

1:55 pm-9:08 am

2 stops18h 13m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

9:10 am-6:37 pm

2 stops10h 27m

Panama City Tocumen Intl

Tue 4/7

10:55 pm-3:14 pm

2 stops15h 19m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 1/27

7:00 am-7:38 pm

2 stops12h 38m

Panama City Tocumen Intl

Mon 2/2

10:00 am-8:58 pm

1 stop10h 58m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:45 am-4:12 pm

1 stop10h 27m

Panama City Tocumen Intl

Mon 4/6

10:55 pm-3:14 pm

2 stops15h 19m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/5

4:40 pm-2:14 pm

1 stop22h 34m

Panama City Tocumen Intl

Tue 4/7

10:55 pm-9:54 am

1 stop9h 59m

$423

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/4

5:30 am-5:07 pm

2 stops11h 37m

Panama City Tocumen Intl

Sun 3/8

10:55 pm-3:32 pm

2 stops15h 37m

$435

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 4/14

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 4/16

2:20 pm-9:11 am

1 stop17h 51m

$490

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Tue 3/10

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-9:13 am

1 stop17h 53m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 57 results
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Best time to book a flight from Ohio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Panama

What is the cheapest month to book a flight from Ohio to Panama?

Currently, May is the cheapest month in which you can book a flight from Ohio to Panama (average of $330). Flying from Ohio to Panama in September is currently the most expensive (average of $480). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to PA?

Find hourly flight availability from Ohio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Ohio to Panama at noon. If you’re flexible enough to do this you can expect to save up to 62% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ohio to Panama?

    Airlines like United Airlines and Delta fly from Ohio to Panama in about 8h 15m. The time it takes to get you to your destination can typically vary by up to 9h 45m. Ohio and Panama are separated by a distance of 2146 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Ohio to Panama one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $174. American Airlines flights start at $174 while deals on Delta start at $232 one-way.

  • Can I find deals for flights from Ohio to Panama that include hotel bookings?

    Yes. In addition to deals on Ohio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Panama.

  • Can I find deals for business class flights from Ohio to Panama?

    Yes. Cheapflights offers flight deals from Ohio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Panama?

    Currently, May is the cheapest month in which you can book a flight from Ohio to Panama (average of $330). Flying from Ohio to Panama in September is currently the most expensive (average of $480). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Ohio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Panama

Discover the top 3 airlines that operate flights from Ohio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$592FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$733FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$575FlexibilityNo cancel feeOn-time69%

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