HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$206+ Cheap flights from Ohio to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ohio to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to Panama

Keep the following information in mind while searching for Ohio to Panama flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$393
(Delta)

One-way from

$222
(Delta)

Popular in

December

Cheapest in

September

Average price

$568
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
Search Deals
From Ohio to Panama
Search Deals
One-way flight from Ohio to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Ohio to Panama

Cheapest flights from Ohio to Panama
Explore the most affordable flight options available from Ohio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:00 amCMH - PTY
1 stop7h 03mDelta
Thu 7/172:23 pmPTY - CMH
1 stop9h 17mDelta
Deal found 4/30$393
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/86:30 amCMH - PTY
1 stop13h 07mUnited Airlines
Thu 7/173:30 pmPTY - CMH
2 stops17h 07mUnited Airlines
Deal found 4/30$398
This Avianca Connect deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:00 amPIT - PTY
2 stops15h 10mMultiple Airlines
Tue 6/33:20 amPTY - PIT
2 stops19h 34mMultiple Airlines
Deal found 4/30$446
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/195:00 amDTW - PTY
1 stop12h 26mMultiple Airlines
Wed 5/289:33 pmPTY - DTW
1 stop13h 42mMultiple Airlines
Deal found 4/30$462
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:15 amCLE - PTY
1 stop9h 10mAmerican Airlines
Fri 7/111:55 pmPTY - CLE
1 stop9h 18mAmerican Airlines
Deal found 4/29$469
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:15 amPIT - PTY
1 stop13h 22mUnited Airlines
Tue 7/87:55 amPTY - PIT
1 stop13h 57mUnited Airlines
Deal found 4/30$469
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/254:57 pmPIT - PTY
2 stops21h 03mAmerican Airlines
Tue 7/81:55 pmPTY - PIT
1 stop8h 48mAmerican Airlines
Deal found 4/30$474
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/299:00 amCVG - PTY
1 stop8h 26mMultiple Airlines
Thu 6/510:25 amPTY - CVG
1 stop7h 39mMultiple Airlines
Deal found 4/29$475
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/296:22 pmCLE - PTY
1 stop22h 50mUnited Airlines
Thu 7/39:45 amPTY - CLE
1 stop11h 01mUnited Airlines
Deal found 4/29$479
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/87:00 amCVG - PTY
1 stop8h 14mUnited Airlines
Mon 8/187:55 amPTY - CVG
1 stop15h 04mUnited Airlines
Deal found 4/30$489
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/307:00 amCAK - PTY
2 stops12h 37mUnited Airlines
Tue 7/87:55 amPTY - CAK
2 stops14h 49mUnited Airlines
Deal found 4/29$502
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:13 amCVG - PTY
1 stop6h 35mDelta
Wed 6/42:13 pmPTY - CVG
1 stop8h 46mDelta
Deal found 4/30$509

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Ohio to Panama that are best for you.

Fly from

Ohio

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 7/8

7:00 am-1:03 pm

1 stop7h 03m

Panama City Tocumen Intl

Thu 7/17

2:23 pm-12:40 am

1 stop9h 17m

$393

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 7/8

6:30 am-6:37 pm

1 stop13h 07m

Panama City Tocumen Intl

Thu 7/17

3:30 pm-9:37 am

2 stops17h 07m

$398

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Wed 5/28

7:00 am-9:10 pm

2 stops15h 10m

Panama City Tocumen Intl

Tue 6/3

3:20 am-11:54 pm

2 stops19h 34m

$446

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 5/19

5:00 am-4:26 pm

1 stop12h 26m

Panama City Tocumen Intl

Wed 5/28

9:33 pm-12:15 pm

1 stop13h 42m

$462

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 7/4

6:15 am-2:25 pm

1 stop9h 10m

Panama City Tocumen Intl

Fri 7/11

1:55 pm-12:13 am

1 stop9h 18m

$469

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Wed 6/25

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Tue 7/8

7:55 am-10:52 pm

1 stop13h 57m

$469

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Wed 6/25

4:57 pm-1:00 pm

2 stops21h 03m

Panama City Tocumen Intl

Tue 7/8

1:55 pm-11:45 am

2 stops20h 50m

$474

CincinnatiPanama City

CVG - PTY

CVGPTY

Cincinnati Cinci./N. Kentucky

Thu 5/29

9:00 am-4:26 pm

1 stop8h 26m

Panama City Tocumen Intl

Thu 6/5

10:25 am-7:04 pm

1 stop7h 39m

$475

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 6/29

6:22 pm-4:12 pm

1 stop22h 50m

Panama City Tocumen Intl

Thu 7/3

9:45 am-9:46 pm

1 stop11h 01m

$479

CincinnatiPanama City

CVG - PTY

CVGPTY

Cincinnati Cinci./N. Kentucky

Fri 8/8

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Mon 8/18

7:55 am-11:59 pm

1 stop15h 04m

$489

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 34 results
1
2
3
4

Best time to book a flight from Ohio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Panama

What is the cheapest month to book a flight from Ohio to Panama?

Currently, October is the cheapest month in which you can book a flight from Ohio to Panama (average of $478). Flying from Ohio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to PA?

Find hourly flight availability from Ohio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Ohio to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from Ohio to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Ohio to Panama one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $222. American Airlines flights start at $228 while deals on Avianca start at $532 one-way.

  • Can I find deals for flights from Ohio to Panama that include hotel bookings?

    Yes. In addition to deals on Ohio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Panama.

  • Can I find deals for business class flights from Ohio to Panama?

    Yes. Cheapflights offers flight deals from Ohio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Panama?

    Currently, October is the cheapest month in which you can book a flight from Ohio to Panama (average of $478). Flying from Ohio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Panama City flights
John F Kennedy Intl to San José flights
Los Angeles to San Salvador flights
Newark to San José flights
Los Angeles to Guatemala City flights
Los Angeles to San José flights
Dulles Intl to San Salvador flights
Newark to Panama City flights
Hobby to San Salvador flights
Miami to Panama City flights
John F Kennedy Intl to San Salvador flights
Dulles Intl to Panama City flights
San Francisco to San José flights
George Bush Intcntl to San Salvador flights
John F Kennedy Intl to Guatemala City flights
LaGuardia to San José flights
Newark to Guatemala City flights
Dallas/Fort Worth to San Salvador flights
Dulles Intl to Guatemala City flights
Newark to Liberia flights
LaGuardia to Panama City flights
Miami to San Salvador flights
Newark to San Salvador flights
Orlando to Panama City flights
Los Angeles to Panama City flights
Hobby to Guatemala City flights
Miami to San José flights
Dallas/Fort Worth to San José flights
Hobby to San José flights
Los Angeles to Liberia flights
Miami to Managua flights
John F Kennedy Intl to Liberia flights
Atlanta to Panama City flights
Atlanta to San José flights
Dulles Intl to San José flights
Atlanta to Guatemala City flights
Reagan-National to San Salvador flights
Fort Lauderdale to San José flights
George Bush Intcntl to Guatemala City flights
Orlando to San José flights
Baltimore to San Salvador flights
George Bush Intcntl to San José flights
Los Angeles to Philip S.W.Goldson flights
O'Hare Intl to Guatemala City flights
LaGuardia to Guatemala City flights
San Francisco to Panama City flights
Dallas/Fort Worth to Philip S.W.Goldson flights
Boston to Guatemala City flights
Baltimore to San José flights
Boston to San Salvador flights

Top 3 airlines flying from Ohio to Panama

Discover the top 3 airlines that operate flights from Ohio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$375Average$588FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$384Average$641FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$449Average$569FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.