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$184+ Cheap flights from Indiana to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Feb 10 — Feb 171
Tue 2/10
Tue 2/17
1 adult, Economy
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Cheap flight deals from Indiana to Panama

Keep the following information in mind while searching for Indiana to Panama flight deals. Data was last updated January 11, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$423
(United Airlines)

One-way from

$184
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$584
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indiana to Panama
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One-way flight from Indiana to Panama
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Highest demand for flights based on searches. 23% potential increase in price ($194 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Indiana to Panama

Cheapest flights from Indiana to Panama
Explore the most affordable flight options available from Indiana to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.

This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:07 amSDF - PTY
2 stops11h 24mUnited Airlines
Sat 4/257:55 amPTY - SDF
2 stops11h 21mUnited Airlines
Deal found 1/9$423
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:00 amSDF - PTY
1 stop11h 07mUnited Airlines
Wed 2/49:55 amPTY - SDF
1 stop12h 04mUnited Airlines
Deal found 1/8$425
This Delta deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:35 pmSDF - PTY
1 stop20h 28mDelta
Thu 4/162:20 pmPTY - SDF
1 stop7h 34mDelta
Deal found 1/9$432
This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/49:00 amSDF - PTY
1 stop11h 02mUnited Airlines
Mon 2/94:41 pmPTY - SDF
1 stop20h 33mUnited Airlines
Deal found 1/9$433
This American Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:49 pmSDF - PTY
2 stops21h 51mAmerican Airlines
Mon 3/22:40 pmPTY - SDF
2 stops20h 13mAmerican Airlines
Deal found 1/9$436
This KAYAK deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 amSDF - PTY
1 stop14h 02mMultiple Airlines
Wed 4/19:45 amPTY - SDF
1 stop12h 27mMultiple Airlines
Deal found 1/10$437
This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/58:30 amSDF - PTY
1 stop11h 32mUnited Airlines
Sun 2/84:41 pmPTY - SDF
2 stops20h 43mUnited Airlines
Deal found 1/9$438
This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:15 amSDF - PTY
1 stop7h 57mUnited Airlines
Sun 4/123:30 pmPTY - SDF
1 stop29h 29mUnited Airlines
Deal found 1/9$440
This United Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 amSDF - PTY
1 stop11h 07mUnited Airlines
Tue 3/34:41 pmPTY - SDF
1 stop29h 05mUnited Airlines
Deal found 1/10$442
This United Airlines deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/49:00 amSDF - PTY
1 stop11h 02mUnited Airlines
Sun 2/84:41 pmPTY - SDF
1 stop27h 13mUnited Airlines
Deal found 1/9$443
This KAYAK deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:35 amSDF - PTY
2 stops14h 27mCopa Airlines
Mon 2/94:41 pmPTY - SDF
1 stop20h 33mCopa Airlines
Deal found 1/9$444
This Avianca Connect deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:28 amIND - PTY
2 stops15h 12mMultiple Airlines
Tue 3/32:55 amPTY - IND
2 stops19h 53mMultiple Airlines
Deal found 1/10$445

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 11, 2026.
Use the filters below to find and compare flights from Indiana to Panama that are best for you.

Fly from

Indiana

Fly to

Panama

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/21

7:20 am-6:37 pm

2 stops12h 17m

Panama City Tocumen Intl

Sat 4/25

7:55 am-8:16 pm

2 stops11h 21m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 3/17

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Thu 4/16

2:20 pm-11:59 pm

1 stop8h 39m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 3/17

6:00 am-1:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Wed 4/15

7:55 am-9:59 pm

1 stop13h 04m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/23

5:33 am-1:50 pm

1 stop8h 17m

Panama City Tocumen Intl

Wed 3/4

3:15 pm-11:58 pm

1 stop8h 43m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 3/18

6:00 am-4:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Wed 4/15

10:00 am-9:59 pm

1 stop10h 59m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 5/18

7:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 6/3

2:20 pm-11:59 pm

1 stop8h 39m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/16

6:00 am-6:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Tue 4/14

7:55 am-9:59 pm

1 stop13h 04m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/2

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Wed 2/4

9:55 am-9:59 pm

1 stop12h 04m

$425

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 2/25

5:35 am-5:07 pm

2 stops11h 32m

Panama City Tocumen Intl

Wed 3/4

10:00 am-7:55 pm

1 stop9h 55m

$429

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 2/25

9:28 am-12:40 am

2 stops15h 12m

Panama City Tocumen Intl

Tue 3/3

2:55 am-10:48 pm

2 stops19h 53m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/10

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Panama

What is the cheapest month to book a flight from Indiana to Panama?

Currently, September is the cheapest month in which you can book a flight from Indiana to Panama (average of $463). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Panama?

    Airlines like United Airlines, Delta, and American Airlines fly from Indiana to Panama in about 8h 03m. The time it takes to get you to your destination can typically vary by up to 9h 42m. Indiana and Panama are separated by a distance of 2048 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Indiana to Panama that include hotel bookings?

    Yes. In addition to deals on Indiana to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Panama.

  • Can I find deals for business class flights from Indiana to Panama?

    Yes. Cheapflights offers flight deals from Indiana to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Panama?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Panama (average of $463). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San José flights
John F Kennedy Intl to Panama City flights
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Reagan-National to San José flights
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Baltimore to San Salvador flights
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Atlanta to San José flights
Boston to San José flights
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LaGuardia to Liberia flights
Orlando to San José flights
Dallas/Fort Worth to Panama City flights
Miami to San José flights
O'Hare Intl to Panama City flights
Hobby to Panama City flights
Orlando to Panama City flights
Dulles Intl to Guatemala City flights
Denver to San José flights
Los Angeles to Liberia flights
Miami to Managua flights
Atlanta to Panama City flights
Denver to Liberia flights
San Francisco to Panama City flights

Top 3 airlines flying from Indiana to Panama

Discover the top 3 airlines that operate flights from Indiana to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$642FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$618FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$622FlexibilityNo cancel feeOn-timeN/A

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