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$179+ Cheap flights from Indiana to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Indiana to Panama

Keep the following information in mind while searching for Indiana to Panama flight deals. Data was last updated August 16, 2025.

Round-trip from

$388
(Avianca Connect)

One-way from

$194
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$630
From Indiana to Panama
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One-way flight from Indiana to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Indiana to Panama

Cheapest flights from Indiana to Panama
Explore the most affordable flight options available from Indiana to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:35 amIND - PTY
2 stops18h 25mMultiple Airlines
Tue 11/112:55 amPTY - IND
2 stops20h 01mMultiple Airlines
Deal found 8/15$388
This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/268:23 amSDF - PTY
2 stops13h 47mMultiple Airlines
Sun 9/283:20 amPTY - SDF
2 stops17h 44mMultiple Airlines
Deal found 8/14$397
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:00 pmSDF - PTY
1 stop19h 50mDelta
Tue 9/92:05 pmPTY - SDF
1 stop8h 51mDelta
Deal found 8/15$415
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amSDF - PTY
1 stop7h 56mDelta
Thu 10/232:21 pmPTY - SDF
1 stop7h 13mDelta
Deal found 8/14$423
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:35 pmORD - PTY
1 stop10h 10mAvianca
Sat 9/203:20 amPTY - ORD
1 stop9h 55mAvianca
Deal found 8/15$428
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/189:35 amSDF - PTY
1 stop7h 37mUnited Airlines
Wed 8/273:30 pmPTY - SDF
2 stops17h 32mUnited Airlines
Deal found 8/15$428
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:09 amSDF - PTY
1 stop6h 47mDelta
Wed 10/222:21 pmPTY - SDF
1 stop8h 38mDelta
Deal found 8/14$430
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:05 amORD - PTY
2 stops19h 55mMultiple Airlines
Sun 11/25:55 pmPTY - ORD
2 stops16h 27mMultiple Airlines
Deal found 8/14$434
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/195:02 pmSDF - PTY
2 stops22h 01mAmerican Airlines
Wed 10/223:15 pmPTY - SDF
2 stops22h 51mAmerican Airlines
Deal found 8/14$435
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1010:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Mon 9/156:16 pmPTY - ORD
1 stop15h 02mMultiple Airlines
Deal found 8/15$437
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:31 pmSDF - PTY
2 stops18h 05mAmerican Airlines
Sun 11/232:43 pmPTY - SDF
1 stop8h 56mAmerican Airlines
Deal found 8/15$440
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:56 pmORD - PTY
3 stops24h 14mMultiple Airlines
Sun 9/213:20 amPTY - ORD
2 stops19h 28mMultiple Airlines
Deal found 8/13$445

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Indiana to Panama that are best for you.

Fly from

Indiana

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 11/8

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Tue 11/11

2:55 am-10:56 pm

2 stops20h 01m

$388

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/26

8:23 am-9:10 pm

2 stops13h 47m

Panama City Tocumen Intl

Sun 9/28

3:20 am-10:04 pm

2 stops17h 44m

$397

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 9/1

6:00 pm-12:50 pm

1 stop19h 50m

Panama City Tocumen Intl

Tue 9/9

2:05 pm-11:56 pm

1 stop8h 51m

$415

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 10/23

9:40 am-6:37 pm

1 stop9h 57m

Panama City Tocumen Intl

Mon 10/27

7:55 am-9:57 pm

1 stop13h 02m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 11/4

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

Tue 11/18

8:55 am-9:57 pm

1 stop13h 02m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 10/20

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Thu 10/23

2:21 pm-10:34 pm

1 stop7h 13m

$423

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 10/28

11:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Sun 11/2

9:45 am-8:20 pm

1 stop11h 35m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 11/4

11:19 am-1:36 pm

2 stops26h 17m

Panama City Tocumen Intl

Tue 11/18

2:43 pm-10:45 am

2 stops20h 02m

$428

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 11/14

10:20 pm-4:55 pm

1 stop17h 35m

Panama City Tocumen Intl

Thu 11/20

2:55 am-8:20 pm

1 stop18h 25m

$428

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 11/7

10:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Mon 11/10

9:45 am-8:20 pm

1 stop11h 35m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 58 results
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Best time to book a flight from Indiana to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Panama

What is the cheapest month to book a flight from Indiana to Panama?

Currently, October is the cheapest month in which you can book a flight from Indiana to Panama (average of $478). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to PA?

Find hourly flight availability from Indiana to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Panama as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Indiana to Panama one-way?

    One-way options have recently been found by users for as low as $194 on Avianca. Other airlines that offer cheap prices include Delta from $221 and American Airlines from $248 one-way.

  • Can I find deals for flights from Indiana to Panama that include hotel bookings?

    Yes. In addition to deals on Indiana to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Panama.

  • Can I find deals for business class flights from Indiana to Panama?

    Yes. Cheapflights offers flight deals from Indiana to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indiana to Panama (average of $478). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Panama City flights
John F Kennedy Intl to San José flights
Dulles Intl to San Salvador flights
Newark to San José flights
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George Bush Intcntl to San Salvador flights
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LaGuardia to San José flights
Dallas/Fort Worth to Panama City flights
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Dulles Intl to San José flights
O'Hare Intl to San José flights
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Newark to Liberia flights
Atlanta to San José flights
San Francisco to San José flights
Newark to San Salvador flights
Baltimore to San Salvador flights
George Bush Intcntl to San José flights
O'Hare Intl to Panama City flights
Boston to Panama City flights
John F Kennedy Intl to Liberia flights
Los Angeles to Philip S.W.Goldson flights
Miami to San Salvador flights
Miami to Managua flights
Denver to San José flights
Dulles Intl to Guatemala City flights
Tampa to Panama City flights
Reagan-National to San Salvador flights
Orlando to Panama City flights
Boston to San José flights
Miami to San José flights
Cincinnati to Panama City flights
LaGuardia to San Salvador flights
O'Hare Intl to Guatemala City flights
Baltimore to San José flights
Dallas/Fort Worth to San José flights
Ontario to San Salvador flights

Top 3 airlines flying from Indiana to Panama

Discover the top 3 airlines that operate flights from Indiana to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$652FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$604FlexibilityNo cancel feeOn-time69%
DeltaCheapest$477Average$576FlexibilityNo cancel feeOn-timeN/A

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