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Panama City

$226+ Cheap flights from Syracuse (SYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
jan. 29 — feb. 51
tor. 1/29
tor. 2/5
1 adult, Economy
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Cheap flight deals from Syracuse to Panama City

Cheapest flights from Syracuse to Panama City
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on december 30, 2025.

This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/315:30 amSYR - PTY
1 stop8h 25mUnited Airlines
lør. 1/34:41 pmPTY - SYR
2 stops17h 38mUnited Airlines
Deal found 12/29$1,139
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/316:06 pmSYR - PTY
2 stops21h 48mAmerican Airlines
lør. 1/32:53 pmPTY - SYR
2 stops22h 00mAmerican Airlines
Deal found 12/29$1,164
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/315:29 pmSYR - PTY
2 stops20h 24mAmerican Airlines
søn. 1/44:55 pmPTY - SYR
2 stops18h 34mAmerican Airlines
Deal found 12/29$1,169
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons. 12/317:10 pmSYR - PTY
1 stop22h 45mMultiple Airlines
søn. 1/49:11 amPTY - SYR
1 stop10h 07mMultiple Airlines
Deal found 12/29$2,180

Find flight deals from Syracuse to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated december 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$573
(American Airlines)

One-way from

$226
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$2,176
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
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From Syracuse Hancock Intl to Panama City Tocumen Intl
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One-way flight from Syracuse Hancock Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($313 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 21% potential price decrease ($131 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated december 30, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Syracuse

Fly to

Panama City

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

4:45 pm-3:15 pm

2 stops22h 30m

Panama City Tocumen Intl

søn. 3/8

3:10 pm-11:39 am

2 stops19h 29m

$573

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

4:45 pm-3:15 pm

2 stops22h 30m

Panama City Tocumen Intl

lør. 3/7

4:05 pm-12:12 pm

2 stops20h 07m

$705

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

tor. 2/12

5:27 pm-2:45 pm

2 stops21h 18m

Panama City Tocumen Intl

tor. 2/19

11:35 am-9:42 am

2 stops22h 07m

$833

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

ons. 2/11

11:05 am-8:19 pm

1 stop9h 14m

Panama City Tocumen Intl

ons. 2/18

10:10 am-11:35 am

2 stops25h 25m

$839

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

6:25 am-8:02 pm

2 stops13h 37m

Panama City Tocumen Intl

lør. 3/7

10:00 am-8:18 pm

1 stop10h 18m

$879

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

6:25 am-8:02 pm

2 stops13h 37m

Panama City Tocumen Intl

søn. 3/8

9:30 am-8:18 pm

1 stop9h 48m

$879

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

6:09 am-1:50 pm

1 stop7h 41m

Panama City Tocumen Intl

søn. 3/8

2:28 pm-11:59 pm

1 stop8h 31m

$1,039

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lør. 3/28

5:55 pm-9:10 pm

2 stops28h 15m

Panama City Tocumen Intl

lør. 4/4

10:05 pm-11:57 pm

2 stops48h 52m

$1,104

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

fre. 2/27

7:55 pm-4:15 pm

1 stop20h 20m

Panama City Tocumen Intl

lør. 3/7

7:30 am-5:26 pm

1 stop9h 56m

$1,315

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lør. 3/28

6:02 am-1:03 pm

1 stop8h 01m

Panama City Tocumen Intl

lør. 4/4

2:28 pm-11:59 pm

1 stop8h 31m

$2,304

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 15 results
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Compare providers for flights from Syracuse to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Syracuse-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Syracuse-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama City

What is the cheapest month to book a flight from Syracuse to Panama City?

Currently, May is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $240). Flying from Syracuse to Panama City in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated december 30, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,017 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,017 reviews
Delta
7.9
Good
8,017 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,122 reviews
Delta
7.9
Good
8,017 reviews

Boarding

8.1

Crew

8.5

Entertainment

7.9

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Panama City?

    American Airlines and United Airlines can get you from Syracuse to Panama City in just under 21h 18m. Your travel time can differ by up to 1h 12m. The distance from Syracuse to Panama City is about 2359 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Syracuse to Panama City round-trip?

    United Airlines, at $308, was found to be the cheapest airline from Syracuse to Panama City. An alternate airline flying to your destination would be Delta. United Airlines is 58% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Syracuse to Panama City that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama City.

  • Can I find deals for business class flights from Syracuse to Panama City?

    Yes. Cheapflights offers flight deals from Syracuse to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $240). Flying from Syracuse to Panama City in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Syracuse to Panama City

Discover the top 2 airlines that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated december 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$490Average$611FlexibilityNo cancel feeOn-time69%
DeltaCheapest$491Average$551FlexibilityNo cancel feeOn-timeN/A

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