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Panama City

$517+ Cheap flights from Syracuse (SYR) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Aug 18 — Aug 251
Mon 8/18
Mon 8/25
1 adult, Economy
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Cheap flight deals from Syracuse to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2025.

Round-trip from

$517
(Delta)

Popular in

December

Cheapest in

November

Average price

$623
From Syracuse Hancock Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 4% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Syracuse to Panama City

Cheapest flights from Syracuse to Panama City
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2025.

This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amSYR - PTY
1 stop7h 56mDelta
Fri 10/242:21 pmPTY - SYR
1 stop8h 59mDelta
Deal found 8/11$517
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:20 amSYR - PTY
2 stops13h 17mUnited Airlines
Mon 8/187:55 amPTY - SYR
2 stops14h 53mUnited Airlines
Deal found 8/12$522
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:43 pmSYR - PTY
2 stops25h 54mUnited Airlines
Thu 10/29:45 amPTY - SYR
2 stops12h 57mUnited Airlines
Deal found 8/11$539
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:00 amSYR - PTY
1 stop8h 50mUnited Airlines
Wed 9/179:45 amPTY - SYR
2 stops12h 54mUnited Airlines
Deal found 8/13$610
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:30 amSYR - PTY
1 stop7h 20mDelta
Wed 9/172:10 pmPTY - SYR
1 stop8h 49mDelta
Deal found 8/13$753
This Mytrip deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:57 pmSYR - PTY
3 stops26h 13mMultiple Airlines
Fri 10/2411:00 amPTY - SYR
3 stops29h 11mMultiple Airlines
Deal found 8/11$765
This Avianca deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2910:30 amSYR - PTY
2 stops15h 15mMultiple Airlines
Sun 9/283:20 amPTY - SYR
2 stops14h 17mMultiple Airlines
Deal found 8/11$1,573
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:55 amSYR - PTY
1 stop7h 55mDelta
Mon 9/292:10 pmPTY - SYR
1 stop8h 49mDelta
Deal found 8/11$1,631

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Syracuse

Fly to

Panama City

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 10/20

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Fri 10/24

2:21 pm-12:20 am

1 stop8h 59m

$517

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 10/20

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Fri 10/24

3:30 pm-11:58 am

2 stops19h 28m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/10

5:43 pm-6:37 pm

2 stops25h 54m

Panama City Tocumen Intl

Wed 9/17

3:30 pm-10:18 am

2 stops17h 48m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

5:43 pm-2:14 pm

2 stops21h 31m

Panama City Tocumen Intl

Mon 9/29

10:00 am-9:44 am

2 stops22h 44m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 9/25

5:43 pm-6:37 pm

2 stops25h 54m

Panama City Tocumen Intl

Thu 10/2

9:45 am-11:42 pm

2 stops12h 57m

$539

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/10

6:30 am-12:50 pm

1 stop7h 20m

Panama City Tocumen Intl

Wed 9/17

2:10 pm-11:59 pm

1 stop8h 49m

$753

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 10/20

7:57 pm-9:10 pm

3 stops26h 13m

Panama City Tocumen Intl

Fri 10/24

11:00 am-5:11 pm

3 stops29h 11m

$765

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

10:30 am-12:45 am

2 stops15h 15m

Panama City Tocumen Intl

Sun 9/28

3:20 am-6:37 pm

2 stops14h 17m

$1,573

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Best time to book a flight from Syracuse to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama City

What is the cheapest month to book a flight from Syracuse to Panama City?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 13, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,920 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Panama City round-trip?

    Delta, at $517, was found to be the cheapest airline from Syracuse to Panama City. An alternate airline flying to your destination would be United Airlines. Delta is 19% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Syracuse to Panama City that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama City.

  • Can I find deals for business class flights from Syracuse to Panama City?

    Yes. Cheapflights offers flight deals from Syracuse to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Syracuse to Panama City

Discover the top 2 airlines that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$310Average$611FlexibilityNo cancel feeOn-time69%
DeltaCheapest$466Average$552FlexibilityNo cancel feeOn-timeN/A

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