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Panama City

$227+ Cheap flights from Syracuse (SYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Oct 27 — Nov 31
Mon 10/27
Mon 11/3
1 adult, Economy
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Cheap flight deals from Syracuse to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 27, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$522
(United Airlines)

One-way from

$227
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$597
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
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From Syracuse Hancock Intl to Panama City Tocumen Intl
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One-way flight from Syracuse Hancock Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 8% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Syracuse to Panama City

Cheapest flights from Syracuse to Panama City
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2025.

This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amSYR - PTY
1 stop7h 55mUnited Airlines
Mon 11/178:55 amPTY - SYR
2 stops25h 27mUnited Airlines
Deal found 9/26$522
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:31 amSYR - PTY
2 stops28h 14mUnited Airlines
Tue 11/188:55 amPTY - SYR
2 stops14h 18mUnited Airlines
Deal found 9/24$539
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amSYR - PTY
1 stop7h 56mDelta
Mon 10/272:21 pmPTY - SYR
1 stop8h 59mDelta
Deal found 9/25$544
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amSYR - PTY
1 stop8h 50mUnited Airlines
Mon 10/277:55 amPTY - SYR
2 stops14h 18mUnited Airlines
Deal found 9/25$564
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:40 pmSYR - PTY
2 stops20h 57mAmerican Airlines
Thu 1/84:40 pmPTY - SYR
2 stops19h 07mAmerican Airlines
Deal found 9/24$572
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:40 pmSYR - PTY
2 stops19h 07mAmerican Airlines
Sun 1/114:40 pmPTY - SYR
2 stops19h 07mAmerican Airlines
Deal found 9/26$577
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:40 pmSYR - PTY
2 stops20h 57mAmerican Airlines
Thu 1/82:45 pmPTY - SYR
2 stops20h 52mAmerican Airlines
Deal found 9/25$584
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:45 amSYR - PTY
2 stops13h 53mUnited Airlines
Thu 1/84:41 pmPTY - SYR
2 stops17h 51mUnited Airlines
Deal found 9/26$610
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:50 pmSYR - PTY
2 stops18h 55mUnited Airlines
Sun 11/164:41 pmPTY - SYR
2 stops17h 41mUnited Airlines
Deal found 9/25$611
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:55 pmSYR - PTY
1 stop31h 24mMultiple Airlines
Wed 1/72:55 amPTY - SYR
2 stops16h 29mMultiple Airlines
Deal found 9/25$700
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amSYR - PTY
1 stop8h 21mDelta
Mon 1/123:27 pmPTY - SYR
1 stop8h 32mDelta
Deal found 9/26$900
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amSYR - PTY
1 stop8h 21mDelta
Thu 1/83:27 pmPTY - SYR
1 stop8h 32mDelta
Deal found 9/25$930

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 27, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Syracuse

Fly to

Panama City

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 11/10

7:50 pm-2:45 pm

2 stops18h 55m

Panama City Tocumen Intl

Mon 11/17

8:55 am-11:13 pm

2 stops14h 18m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/10

5:45 am-7:38 pm

2 stops13h 53m

Panama City Tocumen Intl

Mon 1/12

4:41 pm-10:32 am

2 stops17h 51m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Tue 11/11

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 11/18

8:55 am-11:13 pm

2 stops14h 18m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 11/9

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 11/16

4:41 pm-10:22 am

2 stops17h 41m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 10/13

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Mon 10/27

7:55 am-11:13 pm

2 stops14h 18m

$564

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/10

6:40 pm-3:37 pm

2 stops20h 57m

Panama City Tocumen Intl

Thu 1/8

4:40 pm-11:47 am

2 stops19h 07m

$572

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/10

6:40 pm-1:47 pm

2 stops19h 07m

Panama City Tocumen Intl

Sun 1/11

4:40 pm-11:47 am

2 stops19h 07m

$577

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/10

5:45 am-7:38 pm

2 stops13h 53m

Panama City Tocumen Intl

Thu 1/8

4:41 pm-10:32 am

2 stops17h 51m

$610

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 3/14

7:59 pm-1:55 pm

2 stops18h 56m

$227

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 1/18

8:00 am-8:27 pm

2 stops12h 27m

$2,993

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/25

Compare providers for flights from Syracuse to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Panama City in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama City

What is the cheapest month to book a flight from Syracuse to Panama City?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 27, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Panama City?

    United Airlines can get you from Syracuse to Panama City in just under 18h 55m. Your travel time can differ by up to . The distance from Syracuse to Panama City is about 2359 mi.

  • What are the cheapest airlines flying from Syracuse to Panama City round-trip?

    United Airlines, at $490, was found to be the cheapest airline from Syracuse to Panama City. An alternate airline flying to your destination would be Delta. United Airlines is 25% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Syracuse to Panama City that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama City.

  • Can I find deals for business class flights from Syracuse to Panama City?

    Yes. Cheapflights offers flight deals from Syracuse to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Syracuse to Panama City

Discover the top 2 airlines that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$490Average$611FlexibilityNo cancel feeOn-time69%
DeltaCheapest$491Average$551FlexibilityNo cancel feeOn-timeN/A

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