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Panama City

$253+ Cheap flights from Syracuse (SYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Syracuse to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$522
(United Airlines)

One-way from

$253
(Delta)

Popular in

December

Cheapest in

March

Average price

$755
From Syracuse Hancock Intl to Panama City Tocumen Intl
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One-way flight from Syracuse Hancock Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 7% potential increase in price ($53 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Syracuse to Panama City

Cheapest flights from Syracuse to Panama City
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:43 pmSYR - PTY
2 stops25h 54mUnited Airlines
Mon 9/293:30 pmPTY - SYR
2 stops24h 17mUnited Airlines
Deal found 7/29$522
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:19 pmSYR - PTY
2 stops22h 11mAmerican Airlines
Mon 9/293:31 pmPTY - SYR
2 stops19h 00mAmerican Airlines
Deal found 7/28$547
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:05 amSYR - PTY
2 stops18h 15mMultiple Airlines
Sun 11/23:19 amPTY - SYR
2 stops15h 34mMultiple Airlines
Deal found 7/27$1,538
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:55 amSYR - PTY
1 stop7h 55mDelta
Mon 9/292:10 pmPTY - SYR
1 stop8h 49mDelta
Deal found 7/28$1,714
This Gotogate deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/296:10 amSYR - PTY
3 stops33h 35mAvianca
Mon 9/2910:05 pmPTY - SYR
2 stops19h 32mAvianca
Deal found 7/28$2,669

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Syracuse

Fly to

Panama City

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

5:43 pm-6:37 pm

2 stops25h 54m

Panama City Tocumen Intl

Mon 9/29

3:30 pm-4:47 pm

2 stops24h 17m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

5:19 pm-2:30 pm

2 stops22h 11m

Panama City Tocumen Intl

Mon 9/29

3:31 pm-11:31 am

2 stops19h 00m

$547

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 10/31

7:05 am-12:20 am

2 stops18h 15m

Panama City Tocumen Intl

Sun 11/2

3:19 am-6:53 pm

2 stops15h 34m

$1,538

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

5:55 am-12:50 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 9/29

2:10 pm-11:59 pm

1 stop8h 49m

$1,714

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 8/29

6:10 am-2:45 pm

3 stops33h 35m

Panama City Tocumen Intl

Mon 9/29

10:05 pm-6:37 pm

2 stops19h 32m

$2,669

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 12/15

6:50 pm-1:52 pm

1 stop19h 02m

$253

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Tue 12/16

5:21 am-3:25 pm

2 stops10h 04m

$275

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 12/20

11:55 am-8:19 pm

1 stop8h 24m

$860

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/18

11:00 am-8:02 pm

1 stop9h 02m

$997

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Syracuse to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama City

What is the cheapest month to book a flight from Syracuse to Panama City?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,386 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Panama City round-trip?

    United Airlines, at $522, was found to be the cheapest airline from Syracuse to Panama City.Alternate airlines to your destination round-trip include American Airlines and Delta. United Airlines is 16% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Syracuse to Panama City one-way?

    $253 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $275 and $997, respectively.

  • Can I find deals for flights from Syracuse to Panama City that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama City.

  • Can I find deals for business class flights from Syracuse to Panama City?

    Yes. Cheapflights offers flight deals from Syracuse to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $478). Flying from Syracuse to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Syracuse to Panama City

Discover the top airline that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$465Average$551FlexibilityNo cancel feeOn-timeN/A

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