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Panama City

$241+ Cheap flights from Syracuse (SYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
mar. 15 — mar. 221
dom. 3/15
dom. 3/22
1 adult, Economy
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Cheap flight deals from Syracuse to Panama City

Cheapest flights from Syracuse to Panama City
Explore the most affordable flight options available from Syracuse to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 13, 2026.

This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/96:11 pm
SYR
-
PTY
2 stops19h 29m
American Airlines
lun. 3/163:10 pm
PTY
-
SYR
2 stops19h 43m
American Airlines
Deal found 2/9$543
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/287:20 pm
SYR
-
PTY
2 stops17h 50m
American Airlines
sáb. 8/83:20 pm
PTY
-
SYR
2 stops18h 59m
American Airlines
Deal found 2/13$553
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/225:27 pm
SYR
-
PTY
2 stops26h 11m
United Airlines
jue. 3/58:55 am
PTY
-
SYR
2 stops24h 47m
United Airlines
Deal found 2/12$571
This Gurufare deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/202:47 pm
SYR
-
PTY
2 stops29h 15m
Copa Airlines
lun. 3/24:41 pm
PTY
-
SYR
2 stops28h 11m
Copa Airlines
Deal found 2/12$577
This BusinessClass deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/226:37 pm
SYR
-
PTY
1 stop19h 13m
LATAM Airlines
jue. 3/53:15 pm
PTY
-
SYR
1 stop8h 36m
LATAM Airlines
Deal found 2/12$636
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/124:54 pm
SYR
-
PTY
2 stops22h 26m
American Airlines
jue. 3/193:10 pm
PTY
-
SYR
2 stops22h 49m
American Airlines
Deal found 2/12$663
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/18:38 pm
SYR
-
PTY
2 stops28h 02m
Multiple Airlines
vie. 3/612:03 pm
PTY
-
SYR
1 stop25h 06m
Multiple Airlines
Deal found 2/10$671
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/911:39 am
SYR
-
PTY
1 stop9h 40m
Multiple Airlines
lun. 3/1612:03 pm
PTY
-
SYR
2 stops22h 22m
Multiple Airlines
Deal found 2/9$699
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/154:50 pm
SYR
-
PTY
2 stops20h 50m
American Airlines
mar. 2/172:40 pm
PTY
-
SYR
2 stops20h 30m
American Airlines
Deal found 2/11$703
This BusinessClass deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/126:15 am
SYR
-
PTY
1 stop13h 47m
Multiple Airlines
jue. 3/199:30 am
PTY
-
SYR
1 stop25h 53m
Multiple Airlines
Deal found 2/12$714
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/216:15 am
SYR
-
PTY
1 stop7h 47m
Delta
sáb. 4/252:27 pm
PTY
-
SYR
1 stop8h 32m
Delta
Deal found 2/11$723

Find flight deals from Syracuse to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated febrero 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$553
(American Airlines)

One-way from

$241
(American Airlines)

Popular in

February

Cheapest in

October

Average price

$948
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
Search Deals
From Syracuse Hancock Intl to Panama City Tocumen Intl
Search Deals
One-way flight from Syracuse Hancock Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($119 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 13, 2026.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Syracuse

Fly to

Panama City

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lun. 3/9

6:11 pm-12:40 pm

2 stops19h 29m

Panama City Tocumen Intl

lun. 3/16

3:10 pm-11:53 am

2 stops19h 43m

$543

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

mar. 4/21

6:00 am-7:31 pm

2 stops14h 31m

Panama City Tocumen Intl

sáb. 4/25

10:00 am-9:50 am

2 stops22h 50m

$553

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

dom. 3/1

6:11 pm-3:15 pm

2 stops21h 04m

Panama City Tocumen Intl

vie. 3/6

2:40 pm-12:02 pm

2 stops21h 22m

$553

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

mar. 7/28

7:33 pm-12:10 pm

2 stops17h 37m

Panama City Tocumen Intl

sáb. 8/8

3:20 pm-12:52 pm

2 stops20h 32m

$553

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

dom. 3/1

8:38 pm-12:40 am

2 stops28h 02m

Panama City Tocumen Intl

vie. 3/6

12:03 pm-1:09 pm

1 stop25h 06m

$671

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lun. 3/9

11:39 am-8:19 pm

1 stop9h 40m

Panama City Tocumen Intl

lun. 3/16

12:03 pm-11:25 am

2 stops22h 22m

$699

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

mié. 4/8

7:36 pm-12:46 pm

2 stops18h 10m

$241

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lun. 3/30

6:11 pm-12:40 pm

2 stops19h 29m

$241

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

mié. 2/18

5:27 pm-2:45 pm

2 stops21h 18m

$242

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

lun. 3/30

6:01 am-1:03 pm

1 stop8h 02m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 16 results
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Compare providers for flights from Syracuse to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Panama City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama City

What is the cheapest month to book a flight from Syracuse to Panama City?

Currently, March is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $261). Flying from Syracuse to Panama City in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated febrero 13, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,194 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,194 reviews
Delta
7.9
Good
8,194 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,283 reviews
Delta
7.9
Good
8,194 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Panama City?

    American Airlines and United Airlines can get you from Syracuse to Panama City in just under 14h 31m. Your travel time can differ by up to 4h 58m. The distance from Syracuse to Panama City is about 2359 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Syracuse to Panama City round-trip?

    United Airlines, at $308, was found to be the cheapest airline from Syracuse to Panama City. An alternate airline flying to your destination would be Delta. United Airlines is 50% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Syracuse to Panama City that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama City.

  • Can I find deals for business class flights from Syracuse to Panama City?

    Yes. Cheapflights offers flight deals from Syracuse to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Syracuse to Panama City (average of $261). Flying from Syracuse to Panama City in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Syracuse to Panama City

Discover the top 2 airlines that operate flights from Syracuse to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$308Average$623FlexibilityNo cancel feeOn-time69%
DeltaCheapest$491Average$551FlexibilityNo cancel feeOn-timeN/A

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