
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $702 (Avianca) |
One-way from | $396 (Avianca) |
Popular in | December |
Cheapest in | April |
Average price | $904 |
Good round-trip deal | $838 or less |
Good one-way deal | $804 or less |
Fly from
Fly to
Route
Depart
Return
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sun 2/14
7:05 am-1:20 am
2 stops24h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 1/23
8:00 pm-1:20 am
2 stops35h 20m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Tue 4/6
6:25 pm-9:15 am
2 stops21h 50m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sun 1/24
7:05 am-9:10 am
2 stops32h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sun 4/4
7:05 pm-9:15 am
2 stops21h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Tue 2/2
3:10 pm-7:45 pm
Nonstop10h 35m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Tue 4/6
3:05 pm-6:40 pm
Nonstop10h 35m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Tue 4/6
12:00 pm-4:05 pm
Nonstop11h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Thu 4/22
3:05 pm-6:40 pm
Nonstop10h 35m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 1/16
5:00 pm-4:30 pm
1 stop29h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-6:00 am
Nonstop0h 00m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
Everything you need to know about your flight from Madrid to Panama City
Entertainment
Food
Comfort
Boarding
Overall
Crew
Reviews
Kevin,Dec 2025
BOS - EWR
Entertainment
Food
Comfort
Boarding
Overall
Crew
Reviews
Kevin,Dec 2025
BOS - EWR
Entertainment
Food
Comfort
Boarding
Overall
Crew
Reviews
Kevin,Dec 2025
BOS - EWR
Entertainment
Food
Comfort
Boarding
Overall
Crew
Reviews
Kevin,Dec 2025
BOS - EWR
Entertainment
Food
Comfort
Boarding
Overall
Crew
Reviews
Kevin,Dec 2025
BOS - EWR
Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$642 | Average$847 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$644 | Average$1,196 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$732 | Average$1,322 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$757 | Average$1,150 | FlexibilityNo cancel fee | On-time77% |