$356+ Cheap flights from Madrid, Spain (MAD) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — PTY
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Find cheap flights from Madrid to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Madrid Barajas to Panama City Tocumen Intl are usually found in April or May, booked 35 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from Madrid to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madrid to Panama CityExplore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Air Europa deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:05 pm -
Nonstop10h 35m
Mon 9/218:25 pm -
Nonstop9h 50m
Deal found 8/12![Air Europa logo]()
$800
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:30 am -
2 stops36h 25m
Sat 9/52:30 pm -
2 stops56h 50m
Deal found 8/9![Delta logo]()
$801
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:00 am -
2 stops34h 05m
Tue 12/83:30 pm -
2 stops39h 50m
Deal found 8/9![Delta logo]()
$805
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:35 pm -
2 stops29h 23m
Sat 10/102:24 pm -
2 stops43h 21m
Deal found 8/7![Delta logo]()
$814
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am -
1 stop34h 05m
Fri 9/182:23 pm -
2 stops42h 12m
Deal found 8/11![Delta logo]()
$815
This KLM deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop17h 50m
Wed 10/76:50 pm -
1 stop17h 45m
Deal found 8/8![KLM logo]()
$816
This KLM deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop17h 50m
Wed 10/146:50 pm -
1 stop21h 35m
Deal found 8/11![KLM logo]()
$817
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:20 pm -
2 stops31h 38m
Fri 9/182:23 pm -
2 stops56h 57m
Deal found 8/12![Delta logo]()
$819
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
2 stops37h 58m
Thu 10/152:24 pm -
2 stops56h 56m
Deal found 8/11![Delta logo]()
$820
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:50 am -
1 stop34h 08m
Tue 10/62:24 pm -
1 stop14h 51m
Deal found 8/8![Delta logo]()
$822
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:35 pm -
2 stops53h 30m
Sun 9/202:23 pm -
2 stops32h 57m
Deal found 8/11![Delta logo]()
$823
This Iberia deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:55 pm -
Nonstop10h 40m
Wed 11/256:35 pm -
Nonstop10h 05m
Deal found 8/11![Iberia logo]()
$824
Best flights from Madrid to Panama CityDiscover carefully curated flight deals from Madrid to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Madrid to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:00 am -
2 stops60h 58m
Sun 9/272:23 pm -
2 stops56h 57m
Deal found 8/7![Delta logo]()
$826
This Air Europa deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:05 pm -
Nonstop10h 35m
Thu 11/269:30 pm -
Nonstop9h 35m
Deal found 8/11![Air Europa logo]()
$863
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:55 am -
2 stops20h 36m
Sun 9/273:30 pm -
3 stops34h 20m
Deal found 8/12![United Airlines logo]()
$998
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2712:20 pm -
2 stops55h 38m
Sat 10/102:24 pm -
2 stops37h 56m
Deal found 8/7![Delta logo]()
$871
This Air Europa deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/13:10 pm -
Nonstop10h 35m
Fri 2/129:30 pm -
Nonstop9h 35m
Deal found 8/10![Air Europa logo]()
$903
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:15 am -
2 stops38h 22m
Sun 10/49:45 am -
1 stop16h 15m
Deal found 8/7![United Airlines logo]()
$1,004
This Air Europa deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:05 pm -
Nonstop10h 35m
Mon 9/148:25 pm -
Nonstop9h 50m
Deal found 8/8![Air Europa logo]()
$966
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:15 am -
2 stops38h 22m
Sun 10/119:45 am -
1 stop16h 15m
Deal found 8/7![United Airlines logo]()
$1,004
This Air Europa deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:05 pm -
Nonstop10h 35m
Fri 9/188:25 pm -
Nonstop9h 50m
Deal found 8/12![Air Europa logo]()
$967
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:15 am -
2 stops38h 22m
Wed 9/309:45 am -
1 stop16h 15m
Deal found 8/9![United Airlines logo]()
$1,006
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:25 pm -
2 stops36h 37m
Sun 2/710:00 am -
1 stop17h 15m
Deal found 8/12![United Airlines logo]()
$1,012
Last-minute flights from Madrid to Panama CityDiscover last-minute flight deals from Madrid to Panama City. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Panama City. Data last updated August 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:30 am -
2 stops36h 25m
Sat 9/52:30 pm -
2 stops56h 50m
Deal found 8/9![Delta logo]()
$801
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am -
1 stop34h 05m
Fri 9/182:23 pm -
2 stops42h 12m
Deal found 8/11![Delta logo]()
$815
This Iberia deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:55 pm -
Nonstop10h 40m
Wed 11/256:35 pm -
Nonstop10h 05m
Deal found 8/11![Iberia logo]()
$824
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:35 pm -
2 stops53h 30m
Thu 9/242:23 pm -
2 stops56h 57m
Deal found 8/11![Delta logo]()
$823
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:20 pm -
2 stops31h 38m
Sun 9/202:23 pm -
2 stops32h 57m
Deal found 8/12![Delta logo]()
$819
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
2 stops37h 58m
Thu 10/152:24 pm -
2 stops56h 56m
Deal found 8/11![Delta logo]()
$820
This KLM deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop17h 50m
Wed 10/146:50 pm -
1 stop21h 35m
Deal found 8/11![KLM logo]()
$817
This Air Europa deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:05 pm -
Nonstop10h 35m
Mon 9/218:25 pm -
Nonstop9h 50m
Deal found 8/12![Air Europa logo]()
$800
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:00 am -
2 stops60h 58m
Sun 9/272:23 pm -
2 stops56h 57m
Deal found 8/11![Delta logo]()
$826
This KLM deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop17h 50m
Wed 10/76:50 pm -
1 stop17h 45m
Deal found 8/8![KLM logo]()
$816
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:50 am -
1 stop34h 08m
Tue 10/62:24 pm -
1 stop14h 51m
Deal found 8/8![Delta logo]()
$822
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:35 pm -
2 stops29h 23m
Sat 10/102:24 pm -
2 stops43h 21m
Deal found 8/7![Delta logo]()
$814
One-way flights from Madrid to Panama CitySearch for one-way flight options from Madrid to Panama City. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Madrid to Panama City. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:05 pm -
1 stop36h 50m
Deal found 8/9![Avianca logo]()
$356
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/111:25 am -
2 stops19h 15m
Deal found 8/12![Multiple Airlines logo]()
$426
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:20 pm -
2 stops21h 30m
Deal found 8/12![Multiple Airlines logo]()
$459
This Avianca deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/110:25 am -
2 stops20h 15m
Deal found 8/11![Avianca logo]()
$466
This Avianca deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:10 am -
1 stop23h 25m
Deal found 8/11![Avianca logo]()
$467
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:05 am -
1 stop34h 10m
Deal found 8/9![Avianca logo]()
$502
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:30 am -
2 stops24h 05m
Deal found 8/10![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:25 pm -
1 stop17h 40m
Deal found 8/8![Multiple Airlines logo]()
$563
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 am -
1 stop15h 50m
Deal found 8/10![Avianca logo]()
$564
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:20 pm -
2 stops18h 35m
Deal found 8/10![Multiple Airlines logo]()
$569
Find flight deals from Madrid to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $788 (Iberia) |
One-way from | $356 (Avianca) |
Popular in | December |
Cheapest in | April |
Average price | $1,051 |
Good round-trip deal | $1,048 or less |
Good one-way deal | $861 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sun 9/20
7:00 am-12:58 pm
2 stops60h 58m
Panama City Tocumen Intl
Sun 9/27
2:23 pm-6:20 am
2 stops56h 57m
$826
Quickest round-trip
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Mon 8/31
3:05 pm-6:40 pm
Nonstop10h 35m
Panama City Tocumen Intl
Thu 11/26
9:30 pm-1:05 pm
Nonstop9h 35m
$863
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sun 9/27
12:20 pm-12:58 pm
2 stops55h 38m
Panama City Tocumen Intl
Sat 10/10
2:24 pm-11:20 am
2 stops37h 56m
$871
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Mon 2/1
3:10 pm-7:45 pm
Nonstop10h 35m
Panama City Tocumen Intl
Fri 2/12
9:30 pm-1:05 pm
Nonstop9h 35m
$903
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 8/22
3:05 pm-6:40 pm
Nonstop10h 35m
Panama City Tocumen Intl
Mon 9/14
8:25 pm-1:15 pm
Nonstop9h 50m
$966
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 8/22
3:05 pm-6:40 pm
Nonstop10h 35m
Panama City Tocumen Intl
Fri 9/18
8:25 pm-1:15 pm
Nonstop9h 50m
$967
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Mon 9/21
5:55 am-7:31 pm
2 stops20h 36m
Panama City Tocumen Intl
Sun 9/27
3:30 pm-8:50 am
3 stops34h 20m
$998
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 9/26
11:15 am-6:37 pm
2 stops38h 22m
Panama City Tocumen Intl
Sun 10/4
9:45 am-9:00 am
1 stop16h 15m
$1,004
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Sat 9/26
11:15 am-6:37 pm
2 stops38h 22m
Panama City Tocumen Intl
Sun 10/11
9:45 am-9:00 am
1 stop16h 15m
$1,004
MadridPanama City
MAD Madrid Barajas - PTY Panama City Tocumen Intl
MADPTY
Madrid Barajas
Mon 9/14
11:15 am-6:37 pm
2 stops38h 22m
Panama City Tocumen Intl
Wed 9/30
9:45 am-9:00 am
1 stop16h 15m
$1,006
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Madrid to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Panama City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Madrid-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
MAD-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Madrid to Panama City
Prices
Delays
How far ahead should I book a flight from Madrid to Panama City?
The price you pay for your flight from Madrid to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Madrid to Panama City?
Currently, April is the cheapest month in which you can book a flight from Madrid to Panama City (average of $732). Flying from Madrid to Panama City in December is currently the most expensive (average of $1,106). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MAD to PTY?
Find hourly flight availability from Madrid to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 12, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Panama City as you normally would.
How often are flights from Madrid to Panama City delayed?
About 25% of weekly flights between Madrid and Panama City have experienced delays in the past year, with the average delay time being 127 minutes.
What is the most punctual flight time for Madrid to Panama City flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Madrid to Panama City flights?
Over the last year, Iberia have had the lowest number of delays on this route, with just 25% of flights being delayed.
The best insider tips for Madrid to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Madrid to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 12, 2026.
Get a feel of what it's like to fly with Air Europa,Iberia, andAvianca from Madrid to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
6.9
Entertainment
6.5
Overall
7.0
Boarding
7.1
Crew
7.5
Food
6.3
Reviews
1 / 18
6.0
GoodDaniel Alan,Jul 2026
MAD - MIA
Comfort
6.9
Entertainment
6.5
Overall
7.0
Boarding
7.1
Crew
7.5
Food
6.3
Reviews
1 / 18
6.0
GoodDaniel Alan,Jul 2026
MAD - MIA
Comfort
6.9
Entertainment
6.5
Overall
7.0
Boarding
7.1
Crew
7.5
Food
6.3
Reviews
1 / 18
6.0
GoodDaniel Alan,Jul 2026
MAD - MIA
Comfort
6.9
Entertainment
6.5
Overall
7.0
Boarding
7.1
Crew
7.5
Food
6.3
Reviews
1 / 18
6.0
GoodDaniel Alan,Jul 2026
MAD - MIA
Related info for your journey
Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Madrid and Panama City flights
Browse other Madrid and Panama City flight options. Last updated on August 12, 2026.
Other flights from Madrid
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Top 3 airlines flying from Madrid to Panama City
Discover the top 3 airlines that operate flights from Madrid to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$602 | Average$972 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$640 | Average$968 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$693 | Average$1,053 | FlexibilityNo cancel fee | On-time77% |