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Panama City

$322+ Cheap flights from Islip, NY (ISP) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Islip to Panama City

Cheapest flights from Islip to Panama City
Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:25 pm
ISP
-
PTY
2 stops42h 35m
Multiple Airlines
Sun 3/229:45 am
PTY
-
ISP
2 stops37h 01m
Multiple Airlines
Deal found 1/28$808
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2812:25 pm
ISP
-
PTY
2 stops36h 35m
Multiple Airlines
Sun 2/15:50 pm
PTY
-
ISP
2 stops41h 45m
Multiple Airlines
Deal found 1/27$983

Find flight deals from Islip to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$808
(Expedia)

One-way from

$322
(KAYAK)

Popular in

December

Cheapest in

September

Average price

$629
Provider with most accurate pricing for Islip Long Island-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Islip Long Island-Panama City Tocumen Intl flights.
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From Islip Long Island to Panama City Tocumen Intl
Search Deals
One-way flight from Islip Long Island to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Islip to Panama City that are best for you.

Fly from

Islip

Fly to

Panama City

Route

Depart

Return

Price

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Sun 3/15

4:34 pm-2:55 pm

2 stops23h 21m

Panama City Tocumen Intl

Sun 3/22

6:09 pm-12:33 pm

1 stop17h 24m

$997

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Tue 3/10

9:39 am-4:55 pm

2 stops32h 16m

$322

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Mon 3/9

9:39 am-8:50 am

2 stops24h 11m

$420

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Thu 3/12

9:45 am-1:00 am

2 stops16h 15m

$448

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Wed 3/11

9:39 am-2:00 pm

2 stops29h 21m

$485

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Sat 3/14

9:45 am-2:00 pm

2 stops29h 15m

$541

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Sun 3/8

9:39 am-8:50 am

2 stops24h 11m

$541

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Fri 3/13

9:45 am-4:55 pm

2 stops32h 10m

$694

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

  • Most accurate provider: When it comes to deals on Islip, New York-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Islip, New York-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama City

What is the cheapest month to book a flight from Islip, New York to Panama City?

Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in January is currently the most expensive (average of $452). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Islip to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Islip to Panama City that include hotel bookings?

    Yes. In addition to deals on Islip to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama City.

  • Can I find deals for business class flights from Islip to Panama City?

    Yes. Cheapflights offers flight deals from Islip to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in January is currently the most expensive (average of $452). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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