HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$259+ Cheap flights from Islip, NY (ISP) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — PTY
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,832
(Kiwi.com)

One-way from

$259
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$613
Provider with most accurate pricing for Islip Long Island-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Islip Long Island-Panama City Tocumen Intl flights.
Search Deals
From Islip Long Island to Panama City Tocumen Intl
Search Deals
One-way flight from Islip Long Island to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Islip to Panama City

Cheapest flights from Islip to Panama City
Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:40 pmISP - PTY
1 stop15h 53mMultiple Airlines
Sat 1/38:11 amPTY - ISP
2 stops28h 58mMultiple Airlines
Deal found 10/27$1,832

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Islip to Panama City that are best for you.

Fly from

Islip

Fly to

Panama City

Route

Depart

Return

Price

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Sat 12/27

6:40 pm-10:33 am

1 stop15h 53m

Panama City Tocumen Intl

Sat 1/3

8:11 am-1:09 pm

2 stops28h 58m

$1,832

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Thu 12/4

10:19 am-8:18 pm

2 stops33h 59m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Islip to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Panama City in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Islip, New York-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Islip, New York-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Islip, New York-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Islip, New York-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama City

What is the cheapest month to book a flight from Islip, New York to Panama City?

Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in November is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Islip to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Islip to Panama City that include hotel bookings?

    Yes. In addition to deals on Islip to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama City.

  • Can I find deals for business class flights from Islip to Panama City?

    Yes. Cheapflights offers flight deals from Islip to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in November is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.