In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What is the cheapest time of day to fly from ISP to PTY?

When flying from Islip, New York to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Islip, New York-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Panama City flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Islip, New York-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Islip to Panama City that include hotel bookings?

Yes. In addition to deals on Islip to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Islip to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama City.

Can I find deals for business class flights from Islip to Panama City?

Yes. Cheapflights offers flight deals from Islip to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$878+ Cheap Flights from Islip, NY to Panama City

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Cheap flight deals from Islip to Panama City

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Best

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Cheapest flights from Islip to Panama City
Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

Wed 3/258:25 am

ISP

PTY

2 stops17h 15m

Multiple Airlines

Tue 3/313:25 am

PTY

ISP

2 stops18h 10m

Multiple Airlines

Deal found 2/8

$878

Mon 3/238:25 pm

ISP

PTY

2 stops29h 35m

Multiple Airlines

Mon 3/303:10 pm

PTY

ISP

2 stops40h 59m

Multiple Airlines

Deal found 2/5

$905

Find flight deals from Islip to Panama City

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$878 (Expedia)
Popular in	December
Cheapest in	September
Average price	$633

Provider with most accurate pricing for Islip Long Island-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Islip Long Island-Panama City Tocumen Intl flights.

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From Islip Long Island to Panama City Tocumen Intl

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Highest demand for flights based on searches. 7% potential increase in price ($52 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

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Average for round-trip flights in February 2026

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Fly from

Fly to

Route

Depart

Return

Price

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Wed 3/25

8:25 am-12:40 am

2 stops17h 15m

Panama City Tocumen Intl

Tue 3/31

3:25 am-10:35 pm

2 stops18h 10m

$878

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Mon 3/23

8:25 pm-1:00 am

2 stops29h 35m

Panama City Tocumen Intl

Mon 3/30

3:10 pm-9:09 am

2 stops40h 59m

$905

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Most accurate provider: When it comes to deals on Islip, New York-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Islip, New York-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Islip, New York-Panama City flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Islip, New York-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Islip with our price prediction graph.

ISP-PTY

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama City

What is the cheapest month to book a flight from Islip, New York to Panama City?

Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in December is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Can I find deals for flights from Islip to Panama City that include hotel bookings?
Yes. In addition to deals on Islip to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Islip to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama City.
Can I find deals for business class flights from Islip to Panama City?
Yes. Cheapflights offers flight deals from Islip to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Islip, New York to Panama City?
Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in December is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$878+ Cheap flights from Islip, NY (ISP) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Islip to Panama City with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheap flight deals from Islip to Panama City

Cheapest flights from Islip to Panama CityExplore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

Best flights from Islip to Panama CityDiscover carefully curated flight deals from Islip to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.

Discover carefully curated flight deals from Islip to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.

Last-minute flights from Islip to Panama CityDiscover last-minute flight deals from Islip to Panama City. Data last updated February 9, 2026 and is based on user searches.

Discover last-minute flight deals from Islip to Panama City. Data last updated February 9, 2026 and is based on user searches.

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Use the filters below to find and compare flights from Islip to Panama City that are best for you.

Best time to book a flight from Islip to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Islip with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama City

What is the cheapest month to book a flight from Islip, New York to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Islip to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Islip to Panama City that include hotel bookings?

How can I find direct flights from Islip to Panama City?

Can I find deals for business class flights from Islip to Panama City?

What is the cheapest month to book a flight from Islip, New York to Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Islip to Panama City

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Complete your trip

Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Islip to Panama City by cabin class

Find flights from Islip to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Islip and Panama City flights

Browse other Islip and Panama City flight options. Last updated on February 9, 2026.

Other flights from Islip

Browse through other flights departing from Islip. Flights are based on user searches made on Cheapflights and were last updated on February 9, 2026.

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Cheapest flights from Islip to Panama City
Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

Best flights from Islip to Panama City
Discover carefully curated flight deals from Islip to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 9, 2026.

Last-minute flights from Islip to Panama City
Discover last-minute flight deals from Islip to Panama City. Data last updated February 9, 2026 and is based on user searches.