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Panama City

$772+ Cheap flights from Islip, NY (ISP) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — PTY
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Islip to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$771
(Expedia)

Popular in

December

Cheapest in

September

Average price

$618
Provider with most accurate pricing for Islip Long Island-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Islip Long Island-Panama City Tocumen Intl flights.
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From Islip Long Island to Panama City Tocumen Intl
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Highest demand for flights based on searches. 6% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Islip to Panama City

Cheapest flights from Islip to Panama City
Explore the most affordable flight options available from Islip to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:41 amISP - PTY
1 stop8h 46mMultiple Airlines
Sat 2/289:40 amPTY - ISP
1 stop9h 48mMultiple Airlines
Deal found 1/6$772
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2812:25 pmISP - PTY
2 stops44h 25mMultiple Airlines
Sun 2/19:45 amPTY - ISP
2 stops49h 48mMultiple Airlines
Deal found 1/8$774
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:22 pmISP - PTY
2 stops29h 38mMultiple Airlines
Sun 3/152:55 amPTY - ISP
2 stops15h 32mMultiple Airlines
Deal found 1/8$787
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:07 pmISP - PTY
2 stops33h 03mMultiple Airlines
Mon 4/1311:05 amPTY - ISP
2 stops52h 14mMultiple Airlines
Deal found 1/8$884
This Kiwi.com deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/97:25 amISP - PTY
1 stop13h 16mMultiple Airlines
Thu 1/152:55 amPTY - ISP
2 stops17h 14mMultiple Airlines
Deal found 1/8$1,337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Islip to Panama City that are best for you.

Fly from

Islip

Fly to

Panama City

Route

Depart

Return

Price

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Sat 2/21

11:41 am-8:27 pm

1 stop8h 46m

Panama City Tocumen Intl

Sat 2/28

9:40 am-7:28 pm

1 stop9h 48m

$772

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Wed 1/28

12:25 pm-8:50 am

2 stops44h 25m

Panama City Tocumen Intl

Sun 2/1

9:45 am-11:33 am

2 stops49h 48m

$774

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Fri 3/13

8:22 pm-1:00 am

2 stops29h 38m

Panama City Tocumen Intl

Sun 3/15

2:55 am-7:27 pm

2 stops15h 32m

$787

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

Wed 4/8

1:07 pm-9:10 pm

2 stops33h 03m

Panama City Tocumen Intl

Mon 4/13

11:05 am-4:19 pm

2 stops52h 14m

$884

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Compare providers for flights from Islip to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Panama City in January.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Islip, New York-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Islip, New York-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Islip, New York-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Islip, New York-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama City

What is the cheapest month to book a flight from Islip, New York to Panama City?

Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in January is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Islip to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Islip to Panama City that include hotel bookings?

    Yes. In addition to deals on Islip to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama City.

  • Can I find deals for business class flights from Islip to Panama City?

    Yes. Cheapflights offers flight deals from Islip to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama City (average of $201). Flying from Islip, New York to Panama City in January is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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