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$274+ Cheap flights from Lexington (LEX) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — PTY
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Lexington to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$526
(American Airlines)

One-way from

$274
(American Airlines)

Popular in

August

Cheapest in

January

Average price

$653
From Lexington Blue Grass to Panama City Tocumen Intl
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One-way flight from Lexington Blue Grass to Panama City Tocumen Intl
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Highest demand for flights based on searches. 36% potential increase in price ($465 potential increase over avg. RT price).
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Cheapest flight prices on average. 30% potential price decrease ($189 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Lexington to Panama City

Cheapest flights from Lexington to Panama City
Explore the most affordable flight options available from Lexington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:00 pmLEX - PTY
2 stops20h 00mAmerican Airlines
Tue 11/112:43 pmPTY - LEX
2 stops19h 50mAmerican Airlines
Deal found 7/29$526
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 amLEX - PTY
1 stop7h 56mDelta
Tue 11/113:17 pmPTY - LEX
1 stop7h 13mDelta
Deal found 7/29$561
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:48 pmLEX - PTY
2 stops21h 26mUnited Airlines
Sat 9/203:30 pmPTY - LEX
2 stops20h 54mUnited Airlines
Deal found 7/30$606
This United deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:05 amLEX - PTY
2 stops12h 32mMultiple Airlines
Fri 10/243:25 amPTY - LEX
2 stops16h 36mMultiple Airlines
Deal found 7/28$1,118
This Avianca deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:05 amLEX - PTY
2 stops28h 05mAvianca
Mon 11/103:19 amPTY - LEX
2 stops17h 35mAvianca
Deal found 7/29$1,595

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Lexington to Panama City that are best for you.

Fly from

Lexington

Fly to

Panama City

Route

Depart

Return

Price

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/14

7:00 pm-2:00 pm

2 stops20h 00m

Panama City Tocumen Intl

Tue 11/11

2:43 pm-10:33 am

2 stops19h 50m

$526

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/14

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Tue 11/11

3:17 pm-10:30 pm

1 stop7h 13m

$561

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 9/13

5:48 pm-2:14 pm

2 stops21h 26m

Panama City Tocumen Intl

Sat 9/20

3:30 pm-1:24 pm

2 stops20h 54m

$606

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 10/18

7:05 am-6:37 pm

2 stops12h 32m

Panama City Tocumen Intl

Fri 10/24

3:25 am-9:01 pm

2 stops16h 36m

$1,118

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/14

7:05 am-10:10 am

2 stops28h 05m

Panama City Tocumen Intl

Mon 11/10

3:19 am-8:54 pm

2 stops17h 35m

$1,595

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 9/5

4:41 pm-2:31 pm

2 stops22h 50m

$274

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 9/5

7:10 am-12:50 pm

1 stop6h 40m

$288

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 8/8

3:46 pm-2:34 pm

3 stops23h 48m

$3,290

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Lexington to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Panama City

What is the cheapest month to book a flight from Lexington to Panama City?

Currently, October is the cheapest month in which you can book a flight from Lexington to Panama City (average of $478). Flying from Lexington to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to PTY?

Find hourly flight availability from Lexington to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Lexington to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 43% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 31, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Lexington to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,388 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Lexington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Lexington to Panama City round-trip?

    Our cheapest airline available from Lexington to Panama City is American Airlines. Our recent data shows that you can find tickets from as low as $526 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $561 and $606 round-trip. You may be able to fly from Lexington to Panama City for 34% less than the average price by searching for these airlines.

  • Can I find deals for flights from Lexington to Panama City that include hotel bookings?

    Yes. In addition to deals on Lexington to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Panama City.

  • Can I find deals for business class flights from Lexington to Panama City?

    Yes. Cheapflights offers flight deals from Lexington to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Lexington to Panama City (average of $478). Flying from Lexington to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Lexington to Panama City

Discover the top 2 airlines that operate flights from Lexington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$331Average$726FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$386Average$505FlexibilityNo cancel feeOn-time69%

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