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$248+ Cheap flights from Lexington (LEX) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Lexington to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$526
(American Airlines)

One-way from

$248
(American Airlines)

Popular in

August

Cheapest in

January

Average price

$458
From Lexington Blue Grass to Panama City Tocumen Intl
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One-way flight from Lexington Blue Grass to Panama City Tocumen Intl
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Highest demand for flights based on searches. 37% potential increase in price ($483 potential increase over avg. RT price).
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Cheapest flight prices on average. 30% potential price decrease ($189 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Lexington to Panama City

Cheapest flights from Lexington to Panama City
Explore the most affordable flight options available from Lexington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:52 pmLEX - PTY
2 stops23h 11mAmerican Airlines
Tue 10/143:15 pmPTY - LEX
2 stops21h 36mAmerican Airlines
Deal found 9/10$586
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amLEX - PTY
1 stop7h 56mDelta
Wed 10/152:21 pmPTY - LEX
1 stop8h 25mDelta
Deal found 9/11$621
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:34 pmLEX - PTY
2 stops20h 57mAmerican Airlines
Wed 9/241:45 pmPTY - LEX
2 stops19h 47mAmerican Airlines
Deal found 9/10$641
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:20 pmLEX - PTY
2 stops20h 34mAmerican Airlines
Tue 12/304:56 pmPTY - LEX
2 stops20h 29mAmerican Airlines
Deal found 9/11$661
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:34 pmLEX - PTY
2 stops20h 57mAmerican Airlines
Sun 9/283:31 pmPTY - LEX
2 stops23h 05mAmerican Airlines
Deal found 9/9$674
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amLEX - PTY
1 stop7h 56mDelta
Tue 10/142:21 pmPTY - LEX
1 stop8h 25mDelta
Deal found 9/10$730
This United deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:00 amLEX - PTY
2 stops12h 37mMultiple Airlines
Tue 9/233:20 amPTY - LEX
2 stops16h 28mMultiple Airlines
Deal found 9/10$1,072
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amLEX - PTY
1 stop7h 55mDelta
Wed 9/242:10 pmPTY - LEX
1 stop7h 16mDelta
Deal found 9/10$1,151
This United deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:05 amLEX - PTY
2 stops12h 32mMultiple Airlines
Tue 10/710:05 pmPTY - LEX
2 stops21h 56mMultiple Airlines
Deal found 9/10$1,230
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/261:23 pmLEX - PTY
1 stop6h 37mDelta
Tue 12/308:00 amPTY - LEX
1 stop11h 03mDelta
Deal found 9/11$1,639
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amLEX - PTY
1 stop7h 55mDelta
Sun 9/282:10 pmPTY - LEX
1 stop8h 37mDelta
Deal found 9/9$1,660

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Lexington to Panama City that are best for you.

Fly from

Lexington

Fly to

Panama City

Route

Depart

Return

Price

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 1/14

3:50 pm-1:10 pm

2 stops21h 20m

Panama City Tocumen Intl

Fri 1/23

2:45 pm-10:20 am

2 stops19h 35m

$526

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/7

3:52 pm-2:03 pm

2 stops23h 11m

Panama City Tocumen Intl

Tue 10/14

3:15 pm-1:51 pm

2 stops21h 36m

$586

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 10/8

7:19 pm-2:03 pm

2 stops19h 44m

Panama City Tocumen Intl

Wed 10/15

3:15 pm-10:33 am

2 stops18h 18m

$586

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 1/14

5:55 am-2:02 pm

1 stop8h 07m

Panama City Tocumen Intl

Fri 1/23

3:27 pm-11:55 pm

1 stop8h 28m

$612

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 10/8

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Wed 10/15

2:21 pm-11:46 pm

1 stop8h 25m

$621

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 12/26

7:20 pm-3:54 pm

2 stops20h 34m

Panama City Tocumen Intl

Tue 12/30

4:56 pm-1:25 pm

2 stops20h 29m

$661

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/7

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Tue 10/14

2:21 pm-11:46 pm

1 stop8h 25m

$730

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/7

10:37 am-1:50 pm

2 stops28h 13m

Panama City Tocumen Intl

Mon 10/13

3:25 am-9:01 pm

2 stops16h 36m

$1,072

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Tue 10/7

7:05 am-6:37 pm

2 stops12h 32m

Panama City Tocumen Intl

Tue 10/7

10:05 pm-9:01 pm

2 stops21h 56m

$1,230

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 12/26

1:23 pm-8:00 pm

1 stop6h 37m

Panama City Tocumen Intl

Tue 12/30

8:00 am-7:03 pm

1 stop11h 03m

$1,639

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 15 results
1
2

Best time to book a flight from Lexington to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Panama City

What is the cheapest month to book a flight from Lexington to Panama City?

Currently, October is the cheapest month in which you can book a flight from Lexington to Panama City (average of $478). Flying from Lexington to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to PTY?

Find hourly flight availability from Lexington to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Lexington to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 43% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta from Lexington to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Lexington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Panama City?

    American Airlines and Delta can get you from Lexington to Panama City in just under 8h 07m. Your travel time can differ by up to 13h 13m. The distance from Lexington to Panama City is about 2026 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Lexington to Panama City round-trip?

    Our cheapest airline available from Lexington to Panama City is Delta. Our recent data shows that you can find tickets from as low as $530 on this airline. You may be able to fly from Lexington to Panama City for 34% less than the average price by searching for this airline.

  • Can I find deals for flights from Lexington to Panama City that include hotel bookings?

    Yes. In addition to deals on Lexington to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Panama City.

  • Can I find deals for business class flights from Lexington to Panama City?

    Yes. Cheapflights offers flight deals from Lexington to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Lexington to Panama City (average of $478). Flying from Lexington to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Lexington to Panama City

Discover the top airline that operate flights from Lexington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$530Average$776FlexibilityNo cancel feeOn-timeN/A

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