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$248+ Cheap flights from Lexington (LEX) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Lexington to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$526
(American Airlines)

One-way from

$248
(American Airlines)

Popular in

August

Cheapest in

February
Provider with most accurate pricing for Lexington Blue Grass-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Lexington Blue Grass-Panama City Tocumen Intl flights.
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From Lexington Blue Grass to Panama City Tocumen Intl
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One-way flight from Lexington Blue Grass to Panama City Tocumen Intl
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Highest demand for flights based on searches. 36% potential increase in price ($524 potential increase over avg. RT price).
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Cheapest flight prices on average. 27% potential price decrease ($198 potential savings vs. average RT price).
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Find flight deals from Lexington to Panama City

Cheapest flights from Lexington to Panama City
Explore the most affordable flight options available from Lexington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:47 pmLEX - PTY
2 stops20h 58mUnited Airlines
Thu 12/184:41 pmPTY - LEX
2 stops20h 35mUnited Airlines
Deal found 10/27$586
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Mon 1/124:41 pmPTY - LEX
2 stops20h 44mUnited Airlines
Deal found 10/29$604
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Fri 12/511:55 pmPTY - LEX
2 stops13h 27mUnited Airlines
Deal found 10/29$624
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/153:39 pmLEX - PTY
2 stops22h 10mAmerican Airlines
Fri 11/212:43 pmPTY - LEX
2 stops20h 04mAmerican Airlines
Deal found 10/27$626
This deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:05 amLEX - PTY
1 stop8h 16mDelta
Wed 12/318:00 amPTY - LEX
1 stop11h 03mDelta
Deal found 10/27$1,072
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Mon 1/54:41 pmPTY - LEX
2 stops20h 44mUnited Airlines
Deal found 10/29$1,082
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:05 pmLEX - PTY
1 stop6h 54mDelta
Fri 11/213:37 pmPTY - LEX
1 stop8h 27mDelta
Deal found 10/27$1,201
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:05 amLEX - PTY
1 stop13h 30mUnited Airlines
Fri 11/217:50 amPTY - LEX
1 stop15h 54mUnited Airlines
Deal found 10/27$5,105

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Lexington to Panama City that are best for you.

Fly from

Lexington

Fly to

Panama City

Route

Depart

Return

Price

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 3/5

5:02 pm-1:21 pm

2 stops20h 19m

Panama City Tocumen Intl

Wed 3/18

3:50 pm-2:27 pm

2 stops21h 37m

$526

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 12/11

5:47 pm-2:45 pm

2 stops20h 58m

Panama City Tocumen Intl

Thu 12/18

4:41 pm-1:16 pm

2 stops20h 35m

$586

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 11/28

1:59 pm-2:45 pm

2 stops24h 46m

Panama City Tocumen Intl

Mon 1/12

4:41 pm-1:25 pm

2 stops20h 44m

$604

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 11/28

1:59 pm-2:45 pm

2 stops24h 46m

Panama City Tocumen Intl

Fri 12/5

11:55 pm-1:22 pm

2 stops13h 27m

$624

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 11/15

3:39 pm-1:49 pm

2 stops22h 10m

Panama City Tocumen Intl

Fri 11/21

2:43 pm-10:47 am

2 stops20h 04m

$626

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

5:50 pm-4:12 pm

2 stops23h 22m

Panama City Tocumen Intl

Sun 4/12

3:20 pm-4:55 pm

2 stops24h 35m

$637

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

6:31 am-12:10 pm

1 stop6h 39m

Panama City Tocumen Intl

Sun 4/12

1:55 pm-10:32 am

2 stops19h 37m

$792

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 3/5

9:18 am-2:00 pm

2 stops28h 42m

Panama City Tocumen Intl

Wed 3/18

12:03 pm-8:35 am

1 stop19h 32m

$971

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 12/11

8:09 pm-3:42 pm

2 stops19h 33m

$248

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Mon 11/17

7:18 pm-1:49 pm

2 stops18h 31m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 15 results
1
2

Compare providers for flights from Lexington to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Lexington-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Lexington-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Panama City

What is the cheapest month to book a flight from Lexington to Panama City?

Currently, June is the cheapest month in which you can book a flight from Lexington to Panama City (average of $337). Flying from Lexington to Panama City in November is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to PTY?

Find hourly flight availability from Lexington to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Lexington to Panama City in the evening. If you’re flexible enough to do this you can expect to save up to 42% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Delta from Lexington to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Panama City?

    American Airlines and United Airlines can get you from Lexington to Panama City in just under 20h 19m. Your travel time can differ by up to 39m. The distance from Lexington to Panama City is about 2026 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Lexington to Panama City round-trip?

    Our cheapest airline available from Lexington to Panama City is Delta. Our recent data shows that you can find tickets from as low as $665 on this airline. You may be able to fly from Lexington to Panama City for 27% less than the average price by searching for this airline.

  • Can I find deals for flights from Lexington to Panama City that include hotel bookings?

    Yes. In addition to deals on Lexington to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Panama City.

  • Can I find deals for business class flights from Lexington to Panama City?

    Yes. Cheapflights offers flight deals from Lexington to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Lexington to Panama City (average of $337). Flying from Lexington to Panama City in November is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Lexington to Panama City

Discover the top airline that operate flights from Lexington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$665Average$757FlexibilityNo cancel feeOn-timeN/A

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