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Panama City

$194+ Cheap flights from Irvine, CA to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Panama City Tocumen Intl are usually found in August or September, booked 50 days in advance, depart on a Wednesday or Thursday and return on a Thursday

Find flight deals from Irvine to Panama City

Cheapest flights from Irvine to Panama City
Explore the most affordable flight options available from Irvine to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:20 pmLAX - PTY
1 stop8h 10mAvianca
Tue 11/183:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 11/2$527
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:20 pmLAX - PTY
1 stop8h 10mMultiple Airlines
Tue 11/1811:25 amPTY - LAX
3 stops23h 49mMultiple Airlines
Deal found 11/2$528
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:20 pmLAX - PTY
1 stop8h 10mAvianca
Sun 11/167:50 pmPTY - LAX
1 stop18h 45mAvianca
Deal found 11/1$537
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:00 pmLAX - PTY
1 stop18h 30mAvianca
Sun 11/167:50 pmPTY - LAX
1 stop18h 45mAvianca
Deal found 11/2$546
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:00 pmLAX - PTY
1 stop18h 30mAvianca
Mon 11/173:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 11/1$549
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:20 pmLAX - PTY
1 stop8h 10mAvianca
Sat 11/223:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 11/1$551
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:20 pmLAX - PTY
1 stop8h 10mAvianca
Wed 12/33:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 11/2$566
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:20 pmLAX - PTY
2 stops22h 20mMultiple Airlines
Wed 11/1911:25 amPTY - LAX
3 stops24h 45mMultiple Airlines
Deal found 10/31$568
This Gotogate deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:55 pmLAX - PTY
1 stop16h 00mAvianca
Fri 11/142:55 amPTY - LAX
2 stops21h 20mAvianca
Deal found 11/1$572
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:25 pmLAX - PTY
2 stops19h 05mAvianca
Fri 11/143:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 11/1$575

Cheap flight deals from Irvine to Panama City

Keep the following information in mind while searching for Irvine to Panama City flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(Gotogate)

One-way from

$194
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$610
Provider with most accurate pricing for Los Angeles-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Panama City Tocumen Intl flights.
Search Deals
From Irvine to Panama City Tocumen Intl
Search Deals
One-way flight from Irvine to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Irvine to Panama City that are best for you.

Fly from

Irvine

Fly to

Panama City

Route

Depart

Return

Price

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sun 2/8

1:06 am-10:25 am

Nonstop6h 19m

Panama City Tocumen Intl

Sun 2/22

7:55 am-12:05 pm

Nonstop7h 10m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 4/2

12:11 pm-8:39 pm

Nonstop6h 28m

Panama City Tocumen Intl

Mon 4/6

7:55 am-1:00 pm

Nonstop7h 05m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 4/2

12:11 pm-8:39 pm

Nonstop6h 28m

Panama City Tocumen Intl

Sat 4/11

6:24 pm-11:36 pm

Nonstop7h 12m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 2/24

1:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Sun 3/1

6:24 pm-10:39 pm

Nonstop7h 15m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 3/19

2:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Sun 3/29

6:24 pm-11:11 pm

Nonstop6h 47m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 3/10

2:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Sun 3/15

7:55 am-1:05 pm

Nonstop7h 10m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 2/10

1:06 am-10:25 am

Nonstop6h 19m

Panama City Tocumen Intl

Sat 2/28

7:55 am-12:05 pm

Nonstop7h 10m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Fri 4/17

2:11 am-10:25 am

Nonstop6h 14m

Panama City Tocumen Intl

Sat 4/25

7:55 am-1:00 pm

Nonstop7h 05m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Fri 1/9

1:25 am-10:40 am

Nonstop6h 15m

Panama City Tocumen Intl

Tue 1/13

6:24 pm-10:36 pm

Nonstop7h 12m

$608

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 12/25

11:05 am-8:39 pm

Nonstop6h 34m

Panama City Tocumen Intl

Sun 12/28

7:55 am-12:02 pm

Nonstop7h 07m

$608

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 19 results
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Best time to book a flight from Irvine to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Panama City

How far ahead should I book a flight from Irvine to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Panama City. Price data was last updated on October 31, 2025.

Booking 50 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Irvine to Panama City?

Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $300). Flying from Irvine to Panama City in April is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to PTY?

Find hourly flight availability from Irvine to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s typically best to fly out from Irvine to Panama City in the morning. Doing so could potentially save you 17% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Irvine to Panama City

Explore weekly flight availability from Irvine to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 3, 2025.

The most flights from IR9 to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (8 on average).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 3, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Irvine to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,561 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,036 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,467 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Irvine?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Irvine to Panama City. 5 airlines have flights to Tocumen Intl from Irvine on a regular basis. Booking flights from Irvine to Panama City Tocumen Intl should not be difficult; the airport handles an average of 8 inbound flights from Irvine per day.

  • How popular is this Irvine to Panama City flight route?

    Within the past month, 137 users have taken a look at flights from Irvine to Panama City Tocumen Intl.

  • How long is the flight from Irvine to Panama City?

    For as low as $598, Copa Airlines can have you in Panama City from Irvine in 6h 19m. Airlines will cover a distance of 3009 mi. All flights are typically nonstop.

  • What are the most reliable airlines from Irvine to Panama City?

    No one likes to see their flight delayed. When booking a flight from Irvine to Panama City consider choosing EVA Air (97%), Asiana Airlines (97%) or United Airlines (97%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Irvine to Panama City?

    While on average a flight from Irvine to Panama City is generally $1,175, our data shows the cheapest flight currently is $169. When looking at the most popular route, (Los Angeles - Panama City Tocumen Intl), you can expect to pay $526 for that flight.

  • Can I find deals for flights from Irvine to Panama City that include hotel bookings?

    Yes. In addition to deals on Irvine to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Panama City.

  • Can I find deals for business class flights from Irvine to Panama City?

    Yes. Cheapflights offers flight deals from Irvine to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $300). Flying from Irvine to Panama City in April is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Irvine to Panama City

Discover the top 5 airlines that operate flights from Irvine to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$203Average$542FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$299Average$652FlexibilityNo cancel feeOn-time69%
AviancaCheapest$320Average$501FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$504Average$639FlexibilityNo cancel feeOn-time70%
DeltaCheapest$519Average$716FlexibilityNo cancel feeOn-timeN/A

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