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Panama City

$391+ Cheap flights from Greenville (GSP) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Greenville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$391
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$485
From Greenville to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:37 pmGSP - PTY
2 stops18h 54mAmerican Airlines
Wed 10/83:15 pmPTY - GSP
2 stops20h 15mAmerican Airlines
Deal found 9/11$408
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:05 amGSP - PTY
1 stop8h 45mUnited Airlines
Wed 10/83:30 pmPTY - GSP
1 stop30h 09mUnited Airlines
Deal found 9/11$412
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:33 pmGSP - PTY
2 stops20h 58mAmerican Airlines
Wed 10/83:15 pmPTY - GSP
2 stops20h 15mAmerican Airlines
Deal found 9/11$428
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:05 amGSP - PTY
1 stop8h 45mUnited Airlines
Sat 11/13:41 pmPTY - GSP
1 stop30h 18mUnited Airlines
Deal found 9/10$510
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:30 amGSP - PTY
1 stop8h 25mDelta
Wed 10/82:21 pmPTY - GSP
1 stop8h 34mDelta
Deal found 9/11$558
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:08 pmGSP - PTY
1 stop17h 45mAmerican Airlines
Tue 1/62:45 pmPTY - GSP
2 stops21h 21mAmerican Airlines
Deal found 9/10$733
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:45 amGSP - PTY
1 stop12h 53mUnited Airlines
Sun 11/24:41 pmPTY - GSP
1 stop29h 18mUnited Airlines
Deal found 9/11$817
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:47 pmGSP - PTY
1 stop27h 53mMultiple Airlines
Tue 10/73:20 amPTY - GSP
2 stops34h 32mMultiple Airlines
Deal found 9/11$1,074

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Greenville

Fly to

Panama City

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/21

6:45 am-2:02 pm

1 stop7h 17m

Panama City Tocumen Intl

Wed 2/4

3:27 pm-11:36 pm

1 stop8h 09m

$391

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/21

5:38 am-3:35 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 2/4

4:40 pm-12:15 am

1 stop7h 35m

$391

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 1/20

5:21 am-3:35 pm

2 stops10h 14m

Panama City Tocumen Intl

Tue 1/27

2:45 pm-12:15 am

1 stop9h 30m

$396

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 9/25

8:37 pm-2:31 pm

2 stops18h 54m

Panama City Tocumen Intl

Wed 10/8

3:15 pm-12:30 pm

2 stops20h 15m

$408

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 2/12

7:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Fri 2/20

11:35 am-9:46 pm

1 stop10h 11m

$409

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 9/25

6:05 am-1:50 pm

1 stop8h 45m

Panama City Tocumen Intl

Wed 10/8

3:30 pm-10:39 pm

1 stop30h 09m

$412

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Fri 9/26

6:33 pm-2:31 pm

2 stops20h 58m

Panama City Tocumen Intl

Wed 10/8

3:15 pm-12:30 pm

2 stops20h 15m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City?

Currently, October is the cheapest month in which you can book a flight from Greenville to Panama City (average of $478). Flying from Greenville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to PTY?

Find hourly flight availability from Greenville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Greenville to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 35% versus a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Greenville to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Panama City?

    Delta and American Airlines can get you from Greenville to Panama City in just under 7h 17m. Your travel time can differ by up to 2h 40m. Greenville and Panama City are separated by a distance of 1792 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Greenville to Panama City round-trip?

    Flying on United Airlines is currently your cheapest option to Panama City, with prices starting at $352. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $371 and $376, respectively. United Airlines is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Panama City that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

  • Can I find deals for business class flights from Greenville to Panama City?

    Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Greenville to Panama City (average of $478). Flying from Greenville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Panama City

Discover the top 3 airlines that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$352Average$401FlexibilityNo cancel feeOn-time69%
DeltaCheapest$371Average$519FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$376Average$577FlexibilityNo cancel feeOn-time71%

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