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Panama City

$341+ Cheap flights from Greenville (GSP) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — PTY
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Greenville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$341
(Delta)

Popular in

March

Cheapest in

November

Average price

$424
From Greenville to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
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Find flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:30 amGSP - PTY
1 stop8h 26mDelta
Tue 10/142:21 pmPTY - GSP
1 stop8h 33mDelta
Deal found 7/29$341
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amGSP - PTY
1 stop9h 00mAmerican Airlines
Tue 10/143:15 pmPTY - GSP
2 stops19h 25mAmerican Airlines
Deal found 7/29$346
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:34 pmGSP - PTY
1 stop26h 03mUnited Airlines
Tue 8/193:30 pmPTY - GSP
1 stop29h 30mUnited Airlines
Deal found 7/29$420
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/229:34 pmGSP - PTY
3 stops27h 26mMultiple Airlines
Sat 11/295:55 pmPTY - GSP
2 stops22h 53mMultiple Airlines
Deal found 7/29$917

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Greenville

Fly to

Panama City

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 10/7

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Tue 10/14

2:21 pm-11:54 pm

1 stop8h 33m

$341

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 10/7

6:00 am-2:00 pm

1 stop9h 00m

Panama City Tocumen Intl

Tue 10/14

3:15 pm-11:40 am

2 stops19h 25m

$346

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 8/13

5:34 pm-4:12 pm

1 stop23h 38m

Panama City Tocumen Intl

Tue 8/19

3:30 pm-10:00 pm

1 stop29h 30m

$420

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 11/22

9:34 pm-1:00 am

3 stops27h 26m

Panama City Tocumen Intl

Sat 11/29

5:55 pm-4:48 pm

2 stops22h 53m

$917

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City?

Currently, October is the cheapest month in which you can book a flight from Greenville to Panama City (average of $478). Flying from Greenville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to PTY?

Find hourly flight availability from Greenville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Greenville to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 35% versus a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Greenville to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Greenville to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $341. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $346 and $420, respectively. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Panama City that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

  • Can I find deals for business class flights from Greenville to Panama City?

    Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Greenville to Panama City (average of $478). Flying from Greenville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Panama City

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Top 3 airlines flying from Greenville to Panama City

Discover the top 3 airlines that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$352Average$423FlexibilityNo cancel feeOn-time69%
DeltaCheapest$371Average$482FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$376Average$577FlexibilityNo cancel feeOn-time71%

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