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Panama City

$191+ Cheap flights from Denver (DEN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in October or August, booked 47 days in advance, depart on a Tuesday or Monday and return on a Saturday

Cheap flight deals from Denver to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$483
(Kiwi.com)

One-way from

$191
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$648

Good round-trip deal

$430 or less

Good one-way deal

$187 or less
From Denver Intl to Panama City Tocumen Intl
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One-way flight from Denver Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Denver Intl to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Denver Intl to Panama City Tocumen Intl.
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Find flight deals from Denver to Panama City

Cheapest flights from Denver to Panama City
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Sun 11/169:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 9/14$483
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:21 pmDEN - PTY
2 stops22h 08mMultiple Airlines
Wed 10/229:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/15$500
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amDEN - PTY
2 stops13h 37mMultiple Airlines
Fri 10/249:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/17$502
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Fri 10/109:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/15$513
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:34 amDEN - PTY
1 stop14h 32mMultiple Airlines
Mon 11/38:10 amPTY - DEN
2 stops13h 16mMultiple Airlines
Deal found 9/16$522
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:34 amDEN - PTY
1 stop16h 46mMultiple Airlines
Sun 11/236:34 pmPTY - DEN
1 stop16h 29mMultiple Airlines
Deal found 9/16$523
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:34 amDEN - PTY
1 stop14h 20mMultiple Airlines
Sat 11/89:43 pmPTY - DEN
1 stop12h 50mMultiple Airlines
Deal found 9/17$538
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Sat 11/1512:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 9/17$548
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:05 amDEN - PTY
1 stop10h 54mDelta
Sun 11/168:05 amPTY - DEN
1 stop9h 08mDelta
Deal found 9/14$552

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Denver

Fly to

Panama City

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Wed 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Mon 3/9

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

7:05 am-8:04 pm

1 stop10h 59m

Panama City Tocumen Intl

Tue 1/27

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Tue 1/27

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Fri 1/30

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 10/21

11:59 pm-9:10 pm

2 stops20h 11m

$191

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 11/8

11:59 pm-8:50 am

2 stops30h 51m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 16 results
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The best insider tips for Denver to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip
Airports
DEN

Use the A Line train for a quick 37-minute ride from Denver Union Station to DEN, avoiding traffic and parking hassles.

Read more about DENby Emily Zemler
PTY

For a quick city transfer, Uber is typically faster and cheaper than taxis from PTY to Panama City.

Read more about PTYby Taryn White
Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Emily Zemler

Emily Zemler

Expert on DEN

Emily Zemler

Emily Zemler

Emily is a freelance writer and book author based in London covering entertainment and travel. Her work has appeared in Los Angeles Times, Observer, and Conde Nast Traveler She has ventured to more than 40 countries and all seven continents, always in search of a great art museum. She has written extensively about hotels, luxury travel, and aviation.

Read more

Best time to book a flight from Denver to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama City

How far ahead should I book a flight from Denver to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Panama City. Price data was last updated on September 12, 2025.

The price you pay for your flight from Denver to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Panama City?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $478). Flying from Denver to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PTY?

Find hourly flight availability from Denver to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Denver to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 20% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,533 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Panama City?

    Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Denver Intl. Booking flights from Denver Intl (DEN) to Tocumen Intl (PTY) should be relatively easy as there is 1 daily flight to Panama City from 4 different airlines. 5h 45m is how long a flight from Denver to Panama City Tocumen Intl will take if you book a nonstop flight.

  • How popular is this Denver to Panama City flight route?

    Flights from Denver Intl to Panama City Tocumen Intl have been viewed 34 times in the past calendar month.

  • How long is the flight from Denver to Panama City?

    Airlines like Copa Airlines fly from Denver to Panama City in about 5h 45m. The time it takes to get you to your destination is usually consistent. Denver and Panama City are separated by a distance of 2634 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Denver to Panama City round-trip?

    Currently priced at $474, Copa Airlines will fly you from Denver to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $527 and $527, respectively. You may be able to fly from Denver to Panama City for 26% less than the average price by searching for these airlines.

  • What are the cheapest flights from Denver to Panama City?

    On average you can expect to pay $728 for a flight from Denver to Panama City. The cheapest flight overall is $138 while the most popular route, (Denver Intl - Panama City Tocumen Intl) is currently priced at $535.

  • Can I find deals for flights from Denver to Panama City that include hotel bookings?

    Yes. In addition to deals on Denver to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama City.

  • Can I find deals for business class flights from Denver to Panama City?

    Yes. Cheapflights offers flight deals from Denver to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $478). Flying from Denver to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Colorado Springs to Panama City flights

Top 4 airlines flying from Denver to Panama City

Discover the top 4 airlines that operate flights from Denver to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$474Average$633FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$825FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$695FlexibilityNo cancel feeOn-time69%

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