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Panama City

$158+ Cheap flights from Denver (DEN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Find cheap flights from Denver to Panama City with Cheapflights

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Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in August or May, booked 71 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Denver to Panama City

Cheapest flights from Denver to Panama City
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Tue 4/219:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/6$464
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:15 am
DEN
-
PTY
2 stops26h 00m
Multiple Airlines
Mon 4/279:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/5$480
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:09 pm
DEN
-
PTY
2 stops17h 57m
Multiple Airlines
Mon 5/119:33 pm
PTY
-
DEN
1 stop13h 57m
Multiple Airlines
Deal found 3/9$482
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
DEN
-
PTY
1 stop15h 49m
Multiple Airlines
Thu 4/239:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/8$489
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
DEN
-
PTY
2 stops13h 31m
Multiple Airlines
Tue 4/219:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/6$495
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Wed 4/226:15 pm
PTY
-
DEN
1 stop16h 25m
Multiple Airlines
Deal found 3/6$497
This Trip.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:05 pm
DEN
-
PTY
2 stops25h 00m
Multiple Airlines
Sun 5/33:05 am
PTY
-
DEN
2 stops32h 25m
Multiple Airlines
Deal found 3/6$502

Find flight deals from Denver to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$464
(Kiwi.com)

One-way from

$158
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$675

Good round-trip deal

$452 or less

Good one-way deal

$253 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Denver Intl to Panama City Tocumen Intl
Search Deals
One-way flight from Denver Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/29

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 5/6

12:56 pm-6:25 pm

Nonstop6h 29m

$547

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/26

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Fri 5/1

12:56 pm-6:25 pm

Nonstop6h 29m

$547

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 8/4

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Tue 8/11

7:55 am-6:06 pm

1 stop11h 11m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 7/16

8:28 pm-2:14 pm

1 stop16h 46m

Panama City Tocumen Intl

Sat 7/25

10:00 am-11:57 pm

1 stop14h 57m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 7/15

8:28 pm-2:14 pm

1 stop16h 46m

Panama City Tocumen Intl

Sat 7/25

3:30 pm-6:47 am

1 stop16h 17m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 4/28

12:55 am-1:02 pm

1 stop11h 07m

Panama City Tocumen Intl

Wed 5/6

2:27 pm-12:36 am

1 stop11h 09m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 5/15

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 5/20

12:56 pm-6:25 pm

Nonstop6h 29m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 5/6

5:10 am-6:37 pm

1 stop12h 27m

Panama City Tocumen Intl

Fri 5/8

7:55 am-10:15 pm

1 stop15h 20m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 4/28

7:45 am-6:37 pm

1 stop9h 52m

Panama City Tocumen Intl

Sun 5/3

3:30 pm-11:58 pm

1 stop9h 28m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/26

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Fri 5/1

3:30 pm-11:58 pm

1 stop9h 28m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Denver to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Panama City in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama City

How far ahead should I book a flight from Denver to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Panama City. Price data was last updated on March 6, 2026.

The price you pay for your flight from Denver to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Panama City?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $438). Flying from Denver to Panama City in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PTY?

Find hourly flight availability from Denver to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama City as you normally would.

How much does it cost to fly round-trip from Denver to Panama City?

The best insider tips for Denver to Panama City flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip
Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Emily Zemler

Emily Zemler

Expert on DEN

Emily is a freelance writer and book author based in London covering entertainment and travel. Her work has appeared in Los Angeles Times, Observer, and Conde Nast Traveler She has ventured to more than 40 countries and all seven continents, always in search of a great art museum. She has written extensively about hotels, luxury travel, and aviation.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 10, 2026.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAmerican Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,569 reviews

Entertainment

6.8

Crew

8.1

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,569 reviews
Copa Airlines
7.5
Good
1,569 reviews

Entertainment

6.8

Crew

8.1

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
United Airlines
7.4
Good
9,409 reviews
Copa Airlines
7.5
Good
1,569 reviews

Entertainment

6.8

Crew

8.1

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
American Airlines
7.1
Good
11,414 reviews
Copa Airlines
7.5
Good
1,569 reviews

Entertainment

6.8

Crew

8.1

Overall

7.5

Food

6.8

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Panama City?

    Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Denver Intl. Booking flights from Denver Intl (DEN) to Tocumen Intl (PTY) should be relatively easy as there is 1 daily flight to Panama City from 3 different airlines. 5h 42m is how long a flight from Denver to Panama City Tocumen Intl will take if you book a nonstop flight.

  • How popular is this Denver to Panama City flight route?

    Flights from Denver Intl to Panama City Tocumen Intl have been viewed 34 times in the past calendar month.

  • What are the cheapest airlines flying from Denver to Panama City round-trip?

    Currently priced at $465, Copa Airlines will fly you from Denver to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $473 and $527, respectively. You may be able to fly from Denver to Panama City for 25% less than the average price by searching for these airlines.

  • What are the cheapest flights from Denver to Panama City?

    On average you can expect to pay $854 for a flight from Denver to Panama City. The cheapest flight overall is $183 while the most popular route, (Denver Intl - Panama City Tocumen Intl) is currently priced at $515.

  • Can I find deals for flights from Denver to Panama City that include hotel bookings?

    Yes. In addition to deals on Denver to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama City.

  • Can I find deals for business class flights from Denver to Panama City?

    Yes. Cheapflights offers flight deals from Denver to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $438). Flying from Denver to Panama City in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Colorado Springs to Panama City flights

Top 3 airlines flying from Denver to Panama City

Discover the top 3 airlines that operate flights from Denver to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$465Average$600FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$473Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$682FlexibilityNo cancel feeOn-time69%

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