What are the cheapest airlines flying from Charlotte to Panama City round-trip?

Our cheapest airline available from Charlotte to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as $436 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $453 and $456 round-trip. United Airlines is 22% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Charlotte to Panama City?

Travelers seeking maximum savings on their Charlotte to Panama City flight should consider departing on Friday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Charlotte to Panama City?

When booking a flight from Charlotte to Panama City, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Charlotte to Panama City?

Flying to your destination on a Friday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Panama City. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Charlotte to Panama City?

To save up to 50% on this flight, we recommend booking at least 22 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Charlotte to Panama City from $558 1-2 weeks out and tickets from $706 for flights departing within the next 72 hours.

What is the cheapest month to fly from Charlotte to Panama City?

Flights from Charlotte to Panama City lean towards being more expensive in December. Prices are generally better when you fly from Charlotte to Panama City in September, with the cheapest ticket starting at $467.

Can I find deals for flights from Charlotte to Panama City that include hotel bookings?

Yes. In addition to deals on Charlotte to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Charlotte to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama City.

Can I find deals for business class flights from Charlotte to Panama City?

Yes. Cheapflights offers flight deals from Charlotte to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$166+ Flights from Charlotte to Panama City

Q: How much does it cost to fly round-trip from Charlotte to Panama City?

Airfare is below average for this route at the moment. Charlotte to Panama City flights typically cost between $514 and $595 in September. The cheapest round-trip price found within the last 3 days was $385 on Multiple Airlines (Sep 4-Sep 7).

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Find cheap flights from Charlotte to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Charlotte Douglas to Panama City Tocumen Intl are usually found in September or May, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Charlotte to Panama City

Round-trip from	$385 (Mytrip)
One-way from	$166 (Kiwi.com)
Popular in	December
Cheapest in	September
Average price	$551

From Charlotte Douglas to Panama City Tocumen Intl

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One-way flight from Charlotte Douglas to Panama City Tocumen Intl

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Highest demand for flights based on searches. 12% potential increase in price ($77 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Charlotte to Panama City

Cheapest flights from Charlotte to Panama City
Explore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Thu 9/410:17 amCLT - PTY

2 stops11h 53mMultiple Airlines

Sun 9/73:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$385

Thu 9/2510:17 amCLT - PTY

2 stops14h 53mMultiple Airlines

Sun 9/283:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/14

$388

Wed 9/105:45 amCLT - PTY

2 stops20h 00mMultiple Airlines

Fri 9/123:25 amPTY - CLT

2 stops18h 34mMultiple Airlines

Deal found 8/13

$389

Thu 9/255:45 amCLT - PTY

2 stops16h 25mMultiple Airlines

Sat 9/273:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/14

$409

Mon 9/17:00 amCLT - PTY

2 stops18h 45mMultiple Airlines

Sun 9/73:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$425

Fri 8/221:49 pmCLT - PTY

1 stop7h 48mMultiple Airlines

Sun 8/249:33 pmPTY - CLT

1 stop12h 29mMultiple Airlines

Deal found 8/14

$452

Mon 10/271:44 pmCLT - PTY

1 stop7h 53mMultiple Airlines

Thu 10/308:25 amPTY - CLT

1 stop12h 32mMultiple Airlines

Deal found 8/13

$459

Thu 11/610:42 pmCLT - PTY

1 stop9h 24mMultiple Airlines

Sun 11/912:33 pmPTY - CLT

1 stop9h 24mMultiple Airlines

Deal found 8/14

$463

Best flights from Charlotte to Panama City
Discover carefully curated flight deals from Charlotte to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Thu 9/410:17 amCLT - PTY

2 stops14h 53mMultiple Airlines

Mon 9/810:05 pmPTY - CLT

2 stops23h 54mMultiple Airlines

Deal found 8/13

$385

Thu 9/255:45 amCLT - PTY

2 stops19h 25mMultiple Airlines

Sun 9/283:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$388

Mon 10/276:00 amCLT - PTY

2 stops19h 40mMultiple Airlines

Wed 10/292:55 amPTY - CLT

2 stops19h 41mMultiple Airlines

Deal found 8/13

$389

Wed 9/105:45 amCLT - PTY

2 stops20h 00mMultiple Airlines

Fri 9/123:25 amPTY - CLT

2 stops18h 34mMultiple Airlines

Deal found 8/13

$389

Thu 9/255:45 amCLT - PTY

2 stops16h 25mMultiple Airlines

Sat 9/273:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/14

$409

Mon 9/17:00 amCLT - PTY

2 stops18h 45mMultiple Airlines

Sun 9/73:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$425

Wed 10/810:17 amCLT - PTY

2 stops11h 53mMultiple Airlines

Sun 10/125:25 pmPTY - CLT

2 stops17h 58mMultiple Airlines

Deal found 8/13

$431

Last-minute flights from Charlotte to Panama City
Discover last-minute flight deals from Charlotte to Panama City. Data last updated August 14, 2025 and is based on user searches.

Wed 8/207:00 amCLT - PTY

1 stop14h 19mMultiple Airlines

Wed 8/2712:03 pmPTY - CLT

1 stop9h 55mMultiple Airlines

Deal found 8/13

$560

Fri 8/221:49 pmCLT - PTY

1 stop7h 48mMultiple Airlines

Sun 8/249:33 pmPTY - CLT

1 stop12h 29mMultiple Airlines

Deal found 8/14

$452

Mon 9/17:00 amCLT - PTY

2 stops18h 45mMultiple Airlines

Sun 9/73:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$425

Thu 9/410:17 amCLT - PTY

2 stops11h 53mMultiple Airlines

Sun 9/73:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/13

$385

Wed 9/105:45 amCLT - PTY

2 stops20h 00mMultiple Airlines

Fri 9/123:25 amPTY - CLT

2 stops18h 34mMultiple Airlines

Deal found 8/13

$389

Thu 9/2510:17 amCLT - PTY

2 stops14h 53mMultiple Airlines

Sun 9/283:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/14

$388

Thu 9/255:45 amCLT - PTY

2 stops16h 25mMultiple Airlines

Sat 9/273:20 amPTY - CLT

2 stops18h 39mMultiple Airlines

Deal found 8/14

$409

One-way flights from Charlotte to Panama City
Search for one-way flight options from Charlotte to Panama City. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Mon 9/11:43 pmCLT - PTY

2 stops12h 02mMultiple Airlines

Deal found 8/13

$166

Sun 8/311:43 pmCLT - PTY

2 stops27h 47mMultiple Airlines

Deal found 8/13

$169

Wed 11/59:49 amCLT - PTY

2 stops23h 01mMultiple Airlines

Deal found 8/14

$172

Sat 8/301:43 pmCLT - PTY

2 stops27h 47mMultiple Airlines

Deal found 8/13

$192

Thu 11/610:42 pmCLT - PTY

2 stops15h 18mMultiple Airlines

Deal found 8/14

$206

Fri 8/291:49 pmCLT - PTY

2 stops11h 56mMultiple Airlines

Deal found 8/13

$210

Tue 11/45:30 amCLT - PTY

1 stop8h 26mDelta

Deal found 8/14

$221

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charlotte to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 9/4

10:17 am-12:10 am

2 stops14h 53m

Panama City Tocumen Intl

Mon 9/8

10:05 pm-10:59 pm

2 stops23h 54m

$385

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 9/25

5:45 am-12:10 am

2 stops19h 25m

Panama City Tocumen Intl

Sun 9/28

3:20 am-10:59 pm

2 stops18h 39m

$388

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 10/27

6:00 am-12:40 am

2 stops19h 40m

Panama City Tocumen Intl

Wed 10/29

2:55 am-11:36 pm

2 stops19h 41m

$389

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 9/10

5:45 am-12:45 am

2 stops20h 00m

Panama City Tocumen Intl

Fri 9/12

3:25 am-10:59 pm

2 stops18h 34m

$389

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 9/25

5:45 am-9:10 pm

2 stops16h 25m

Panama City Tocumen Intl

Sat 9/27

3:20 am-10:59 pm

2 stops18h 39m

$409

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 9/1

7:00 am-12:45 am

2 stops18h 45m

Panama City Tocumen Intl

Sun 9/7

3:20 am-10:59 pm

2 stops18h 39m

$425

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 10/8

10:17 am-9:10 pm

2 stops11h 53m

Panama City Tocumen Intl

Sun 10/12

5:25 pm-12:23 pm

2 stops17h 58m

$431

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 9/1

1:43 pm-12:45 am

2 stops12h 02m

$166

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 8/31

1:43 pm-4:30 pm

2 stops27h 47m

$169

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 11/5

9:49 am-8:50 am

2 stops23h 01m

$172

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 14 results

Best time to book a flight from Charlotte to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charlotte with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama City

How far ahead should I book a flight from Charlotte to Panama City?

Booking 21 days in advance of your planned departure date is, on average, the best time to get cheap flights from Charlotte to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Charlotte to Panama City?

Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama City (average of $478). Flying from Charlotte to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to PTY?

When flying from Charlotte to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 44% versus a flight in the afternoon.

How much does it cost to fly round-trip from Charlotte to Panama City?

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charlotte to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Charlotte to Panama City round-trip?
Our cheapest airline available from Charlotte to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as $436 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $453 and $456 round-trip. United Airlines is 22% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Charlotte to Panama City that include hotel bookings?
Yes. In addition to deals on Charlotte to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Charlotte to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama City.
Can I find deals for business class flights from Charlotte to Panama City?
Yes. Cheapflights offers flight deals from Charlotte to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Charlotte to Panama City?
Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama City (average of $478). Flying from Charlotte to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Charlotte to Panama City

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$436	Average$522	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$453	Average$571	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$456	Average$575	FlexibilityNo cancel fee	On-timeN/A

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$166+ Cheap flights from Charlotte (CLT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Charlotte to Panama City with Cheapflights

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3. Compare prices and book

Cheapflights Tip: The best prices from Charlotte Douglas to Panama City Tocumen Intl are usually found in September or May, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Charlotte to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Charlotte to Panama City

Cheapest flights from Charlotte to Panama CityExplore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charlotte to Panama City that are best for you.

Best time to book a flight from Charlotte to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charlotte with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama City

How far ahead should I book a flight from Charlotte to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Charlotte to Panama City. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Charlotte to Panama City?

What is the cheapest time of day to fly from CLT to PTY?

Find hourly flight availability from Charlotte to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

How much does it cost to fly round-trip from Charlotte to Panama City?

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charlotte to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Charlotte to Panama City round-trip?

Can I find deals for flights from Charlotte to Panama City that include hotel bookings?

How can I find direct flights from Charlotte to Panama City?

Can I find deals for business class flights from Charlotte to Panama City?

What is the cheapest month to book a flight from Charlotte to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charlotte to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charlotte to Panama City

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Cheapest flights from Charlotte to Panama City
Explore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.