$265+ Cheap flights from Charlotte (CLT) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Nov 5 — Nov 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Charlotte to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charlotte to Panama CityExplore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
Explore the most affordable flight options available from Charlotte to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 10/4![Delta logo]()
$595
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:48 am -
1 stop13h 14m
Mon 12/711:35 am -
1 stop10h 24m
Deal found 10/1![United Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:25 pm -
1 stop22h 09m
Fri 12/113:13 pm -
1 stop9h 02m
Deal found 10/6![American Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:45 am -
1 stop7h 14m
Fri 10/232:24 pm -
1 stop8h 30m
Deal found 10/5![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:40 am -
1 stop6h 19m
Tue 11/103:29 pm -
1 stop8h 28m
Deal found 10/5![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop14h 02m
Sat 12/54:41 pm -
1 stop18h 06m
Deal found 10/6![United Airlines logo]()
$639
Best flights from Charlotte to Panama CityDiscover carefully curated flight deals from Charlotte to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
Discover carefully curated flight deals from Charlotte to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 10/3![Delta logo]()
$595
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop13h 18m
Mon 12/1410:00 am -
1 stop11h 07m
Deal found 10/5![United Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:40 am -
1 stop6h 19m
Mon 11/93:29 pm -
1 stop8h 28m
Deal found 10/5![Delta logo]()
$595
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:30 am -
1 stop13h 08m
Mon 1/2510:00 am -
1 stop11h 59m
Deal found 10/5![United Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/198:15 am -
2 stops11h 47m
Tue 1/2610:00 am -
1 stop11h 40m
Deal found 10/1![United Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:45 am -
1 stop7h 14m
Fri 10/232:24 pm -
1 stop8h 30m
Deal found 10/5![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:40 am -
1 stop6h 19m
Tue 11/103:29 pm -
1 stop8h 28m
Deal found 10/5![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:52 am -
1 stop9h 10m
Sun 12/68:55 am -
1 stop13h 04m
Deal found 10/2![United Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
2 stops14h 02m
Sat 12/54:41 pm -
1 stop18h 06m
Deal found 10/3![United Airlines logo]()
$644
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:10 am -
2 stops11h 52m
Sun 11/88:55 am -
1 stop13h 05m
Deal found 10/4![United Airlines logo]()
$764
Last-minute flights from Charlotte to Panama CityDiscover last-minute flight deals from Charlotte to Panama City. Data last updated October 6, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Panama City. Data last updated October 6, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:45 am -
1 stop7h 14m
Fri 10/232:24 pm -
1 stop8h 30m
Deal found 10/5![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:40 am -
1 stop6h 19m
Tue 11/103:29 pm -
1 stop8h 28m
Deal found 10/5![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:48 am -
1 stop13h 14m
Mon 12/711:35 am -
1 stop10h 24m
Deal found 10/1![United Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 10/4![Delta logo]()
$595
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 11/264:25 pm -
1 stop22h 09m
Fri 12/113:13 pm -
1 stop9h 02m
Deal found 10/6![American Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop14h 02m
Sat 12/54:41 pm -
1 stop18h 06m
Deal found 10/6![United Airlines logo]()
$639
One-way flights from Charlotte to Panama CitySearch for one-way flight options from Charlotte to Panama City. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
Search for one-way flight options from Charlotte to Panama City. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:45 am -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:30 pm -
2 stops23h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![United Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:15 am -
2 stops11h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![United Airlines logo]()
$272
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:40 pm -
2 stops23h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/141:57 pm -
1 stop30h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![United Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:25 pm -
1 stop22h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:33 pm -
2 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![United Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:00 am -
2 stops14h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:40 pm -
2 stops24h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:40 pm -
2 stops21h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![United Airlines logo]()
$339
Find flight deals from Charlotte to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $595 (Delta) |
One-way from | $265 (Delta) |
Popular in | June |
Cheapest in | April |
Average price | $588 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
Use the filters below to find and compare flights from Charlotte to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 2/1
6:45 am-1:55 pm
1 stop7h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 10/28
6:45 am-12:59 pm
1 stop7h 14m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 12/2
5:30 am-2:03 pm
1 stop8h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Tue 10/27
6:45 am-12:59 pm
1 stop7h 14m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$265
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Tue 12/1
6:02 am-8:02 pm
1 stop14h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$267
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 2/4
6:00 am-1:26 pm
1 stop7h 26m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$272
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 2/1
8:00 am-8:02 pm
2 stops12h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$272
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 4/1
8:05 am-4:04 am
2 stops20h 59m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$272
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 11/25
6:40 am-7:38 pm
1 stop12h 58m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$272
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 11/26
6:00 am-2:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Sat 12/5
3:29 pm-11:56 pm
1 stop8h 27m
$595
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Charlotte to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Charlotte-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charlotte-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charlotte-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charlotte-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charlotte to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charlotte with our price prediction graph.
CLT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to Panama City
How far ahead should I book a flight from Charlotte to Panama City?
Booking 53 days in advance of your planned departure date is, on average, the best time to get cheap flights from Charlotte to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Charlotte to Panama City?
Currently, April is the cheapest month in which you can book a flight from Charlotte to Panama City (average of $541). Flying from Charlotte to Panama City in June is currently the most expensive (average of $788). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charlotte to Panama City?
Airfare is typical for this route at the moment.
Charlotte to Panama City flights typically cost between $577 and $698 in November.The cheapest round-trip price found within the last 5 days was $595 on Delta (Nov 26-Dec 5).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 6, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charlotte to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Charlotte
Panama City flight routes
Popular flights
Alternative routes for Charlotte to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Panama City by cabin class
Find flights from Charlotte to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Panama City flights
Browse other Charlotte and Panama City flight options. Last updated on October 6, 2026.
Other flights from Charlotte
Browse through other flights departing from Charlotte. Flights are based on user searches made on Cheapflights and were last updated on October 6, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charlotte to Panama City
Discover the top 3 airlines that operate flights from Charlotte to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$431 | Average$598 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$467 | Average$638 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$487 | Average$679 | FlexibilityNo cancel fee | On-time71% |