$205+ Cheap flights from Charlotte (CLT) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Charlotte to PanamaExplore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:30 am -
1 stop8h 34m
Tue 12/13:29 pm -
1 stop17h 17m
Deal found 11/6![Delta logo]()
$485
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 11/10![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 am -
1 stop13h 18m
Tue 12/154:41 pm -
1 stop18h 06m
Deal found 11/10![United Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:50 pm -
2 stops24h 12m
Wed 12/910:00 am -
1 stop11h 07m
Deal found 11/10![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:40 am -
1 stop8h 05m
Mon 12/710:00 am -
1 stop11h 07m
Deal found 11/9![United Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
2 stops14h 02m
Sat 12/54:41 pm -
1 stop18h 06m
Deal found 11/10![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:20 am -
1 stop13h 18m
Sun 12/2711:55 pm -
1 stop9h 19m
Deal found 11/9![United Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop14h 02m
Wed 11/254:41 pm -
1 stop18h 08m
Deal found 11/9![United Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop14h 02m
Mon 11/304:41 pm -
1 stop29h 18m
Deal found 11/10![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 pm -
2 stops38h 30m
Mon 12/149:48 am -
2 stops24h 59m
Deal found 11/9![United Airlines logo]()
$1,031
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:50 pm -
2 stops36h 55m
Sun 12/279:48 am -
2 stops24h 11m
Deal found 11/5![Copa Airlines logo]()
$1,335
Best flights from Charlotte to PanamaDiscover carefully curated flight deals from Charlotte to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Charlotte to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/78:00 am -
1 stop13h 51m
Sat 1/233:29 pm -
1 stop8h 28m
Deal found 11/10![Delta logo]()
$475
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 am -
1 stop10h 52m
Sun 12/610:00 am -
1 stop11h 07m
Deal found 11/9![United Airlines logo]()
$575
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 11/8![Delta logo]()
$494
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 11/10![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:00 am -
1 stop14h 02m
Sun 1/248:55 am -
1 stop13h 13m
Deal found 11/6![United Airlines logo]()
$575
This Ovago deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/87:47 pm -
2 stops12h 45m
Sun 3/148:10 pm -
2 stops45h 31m
Deal found 11/6![Copa Airlines logo]()
$1,232
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/310:25 am -
1 stop9h 37m
Wed 3/38:55 am -
1 stop13h 20m
Deal found 11/9![United Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/126:30 am -
1 stop13h 32m
Sun 3/2110:55 pm -
2 stops24h 04m
Deal found 11/5![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 am -
1 stop10h 52m
Tue 12/1510:00 am -
2 stops13h 59m
Deal found 11/8![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:40 pm -
2 stops24h 22m
Fri 1/228:55 am -
1 stop13h 13m
Deal found 11/6![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:40 pm -
2 stops24h 22m
Sat 1/238:55 am -
1 stop13h 13m
Deal found 11/6![United Airlines logo]()
$580
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:50 pm -
2 stops36h 55m
Sun 12/279:48 am -
2 stops24h 11m
Deal found 11/5![Copa Airlines logo]()
$1,335
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 pm -
2 stops38h 30m
Mon 12/149:48 am -
2 stops24h 59m
Deal found 11/9![United Airlines logo]()
$1,031
Last-minute flights from Charlotte to PanamaDiscover last-minute flight deals from Charlotte to Panama. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Panama. Data last updated November 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop14h 02m
Wed 11/254:41 pm -
1 stop18h 08m
Deal found 11/9![United Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop14h 02m
Mon 11/304:41 pm -
1 stop29h 18m
Deal found 11/10![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:40 am -
1 stop8h 05m
Mon 12/710:00 am -
1 stop11h 07m
Deal found 11/9![United Airlines logo]()
$594
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:30 am -
1 stop8h 34m
Tue 12/13:29 pm -
1 stop17h 17m
Deal found 11/6![Delta logo]()
$485
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 11/10![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:10 am -
2 stops11h 52m
Sat 12/510:00 am -
2 stops24h 05m
Deal found 11/10![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:50 pm -
2 stops24h 12m
Wed 12/910:00 am -
2 stops24h 22m
Deal found 11/10![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:20 am -
1 stop13h 18m
Sun 12/2711:55 pm -
1 stop9h 19m
Deal found 11/9![United Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 am -
1 stop13h 18m
Tue 12/154:41 pm -
1 stop18h 06m
Deal found 11/10![United Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 pm -
2 stops38h 30m
Mon 12/149:48 am -
2 stops24h 59m
Deal found 11/9![United Airlines logo]()
$1,031
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:50 pm -
2 stops36h 55m
Sun 12/279:48 am -
2 stops24h 11m
Deal found 11/5![Copa Airlines logo]()
$1,335
One-way flights from Charlotte to PanamaSearch for one-way flight options from Charlotte to Panama. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from Charlotte to Panama. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:30 am -
1 stop8h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Delta logo]()
$205
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:31 am -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Delta logo]()
$224
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:31 am -
1 stop7h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Delta logo]()
$236
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:31 am -
1 stop7h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Delta logo]()
$247
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:55 am -
1 stop9h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![United Airlines logo]()
$250
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:00 am -
2 stops12h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$255
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:40 pm -
2 stops24h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$260
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:45 pm -
1 stop26h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![United Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
2 stops14h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:48 pm -
1 stop20h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:55 pm -
2 stops24h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop14h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$286
Find flight deals from Charlotte to Panama
Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $475 (Delta) |
One-way from | $205 (Delta) |
Popular in | December |
Cheapest in | April |
Average price | $618 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 11/30
5:30 am-2:04 pm
1 stop8h 34m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Tue 3/16
5:30 am-1:00 pm
1 stop8h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 11/25
6:31 am-2:04 pm
1 stop7h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
Quickest round-trip
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Tue 11/17
6:31 am-2:02 pm
1 stop7h 31m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Tue 12/1
8:15 am-7:38 pm
2 stops11h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$250
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 2/4
9:30 pm-1:26 pm
1 stop15h 56m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 2/10
6:30 am-2:45 pm
1 stop8h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 1/20
10:25 am-8:02 pm
1 stop9h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 1/4
7:50 pm-5:12 pm
2 stops21h 22m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 1/7
8:00 am-9:51 pm
1 stop13h 51m
Panama City Tocumen Intl
Sat 1/23
3:29 pm-11:57 pm
1 stop8h 28m
$475
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Charlotte to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
CLT-PTY
CLT-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to Panama
CLT-PA0
CLT-PTY
CLT-DAV
What is the cheapest month to book a flight from Charlotte to Panama?
Currently, April is the cheapest month in which you can book a flight from Charlotte to Panama (average of $541). Flying from Charlotte to Panama in December is currently the most expensive (average of $796). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Charlotte to Panama?
To ensure you get the cheapest price possible for a flight from Charlotte to Panama, you should look to book at least 64 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charlotte to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Charlotte to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Panama by cabin class
Find flights from Charlotte to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Panama flights
Browse other Charlotte and Panama flight options. Last updated on November 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charlotte to Panama
Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$598 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$487 | Average$708 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$665 | FlexibilityNo cancel fee | On-time69% |