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$222+ Cheap flights from Charlotte (CLT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Charlotte to Panama

Cheapest flights from Charlotte to Panama
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:48 pm
CLT
-
PTY
2 stops29h 12m
Multiple Airlines
Thu 5/143:10 pm
PTY
-
CLT
2 stops19h 33m
Multiple Airlines
Deal found 4/27$396
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:45 am
CLT
-
PTY
1 stop7h 28m
Delta
Wed 9/162:21 pm
PTY
-
CLT
1 stop8h 36m
Delta
Deal found 4/26$449
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:15 am
CLT
-
PTY
2 stops14h 16m
United Airlines
Wed 9/169:45 am
PTY
-
CLT
1 stop9h 29m
United Airlines
Deal found 4/26$453
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:45 am
CLT
-
PTY
1 stop26h 28m
Delta
Wed 9/162:21 pm
PTY
-
CLT
1 stop8h 36m
Delta
Deal found 4/26$455
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:00 am
CLT
-
PTY
1 stop22h 04m
United Airlines
Mon 7/1310:55 pm
PTY
-
CLT
1 stop12h 12m
United Airlines
Deal found 4/28$456
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:16 am
CLT
-
PTY
1 stop9h 54m
American Airlines
Tue 9/223:40 pm
PTY
-
CLT
1 stop15h 42m
American Airlines
Deal found 4/25$459
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:00 am
CLT
-
PTY
1 stop13h 31m
United Airlines
Thu 7/3010:55 pm
PTY
-
CLT
1 stop9h 36m
United Airlines
Deal found 4/25$474
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am
CLT
-
PTY
1 stop6h 13m
Delta
Thu 9/172:21 pm
PTY
-
CLT
1 stop8h 36m
Delta
Deal found 4/26$479

Find flight deals from Charlotte to Panama

Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$396
(Mytrip)

One-way from

$222
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$562
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
Search Deals
From Charlotte Douglas to Panama
Search Deals
One-way flight from Charlotte Douglas to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 10/21

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Wed 10/28

2:21 pm-11:53 pm

1 stop8h 32m

$449

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 7/9

6:00 am-4:04 am

2 stops23h 04m

Panama City Tocumen Intl

Mon 7/13

9:45 am-9:02 pm

1 stop10h 17m

$453

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 7/12

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Wed 7/15

3:30 pm-11:02 am

1 stop18h 32m

$479

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 9/12

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Wed 9/16

2:21 pm-11:57 pm

1 stop8h 36m

$479

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 9/6

7:49 pm-7:31 pm

2 stops24h 42m

Panama City Tocumen Intl

Fri 9/18

3:30 pm-1:50 pm

2 stops21h 20m

$483

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 8/7

8:05 am-6:37 pm

2 stops11h 32m

Panama City Tocumen Intl

Sun 8/9

10:55 pm-11:59 pm

2 stops24h 04m

$526

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 5/27

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Sat 6/6

10:00 am-9:59 pm

1 stop10h 59m

$529

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 6/1

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Wed 6/10

9:45 am-11:59 pm

2 stops13h 14m

$533
Cheapest one-way

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 7/10

8:05 am-4:04 am

2 stops20h 59m

$222

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 5/7

9:07 pm-8:42 pm

2 stops24h 35m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Charlotte to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama

How far ahead should I book a flight from Charlotte to Panama?

To ensure you get the cheapest price possible for a flight from Charlotte to Panama, you should look to book at least 88 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Charlotte to Panama?

Currently, December is the cheapest month in which you can book a flight from Charlotte to Panama (average of $221). Flying from Charlotte to Panama in January is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charlotte to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,465 reviews

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,465 reviews
Delta
7.9
Good
8,465 reviews

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,680 reviews
Delta
7.9
Good
8,465 reviews

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,678 reviews
Delta
7.9
Good
8,465 reviews

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to Panama?

    If you book a flight to Panama from Charlotte, you will be flying from Douglas, which is the city’s only airport. Charlotte Douglas (CLT) is located 5.7 mi from the center of Charlotte.

  • How long is the flight from Charlotte to Panama?

    A quick flight from Charlotte to Panama can take about 8h 26m. Delta provides one of the quickest options available for as low as $449. Airlines will cover a distance of 1808 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Charlotte to Panama that include hotel bookings?

    Yes. In addition to deals on Charlotte to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama.

  • Can I find deals for business class flights from Charlotte to Panama?

    Yes. Cheapflights offers flight deals from Charlotte to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Panama?

    Currently, December is the cheapest month in which you can book a flight from Charlotte to Panama (average of $221). Flying from Charlotte to Panama in January is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Charlotte to Panama

Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$431Average$577FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$441Average$585FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$467Average$547FlexibilityNo cancel feeOn-time69%

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