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Panama City

$370+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Nov 25 — Dec 21
Tue 11/25
Tue 12/2
1 adult, Economy
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Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2025.

This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:30 amCHS - PTY
1 stop7h 51mDelta
Tue 12/163:46 pmPTY - CHS
1 stop8h 04mDelta
Deal found 10/25$370
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:12 pmCHS - PTY
2 stops20h 30mAmerican Airlines
Thu 12/112:50 pmPTY - CHS
1 stop9h 56mAmerican Airlines
Deal found 10/24$374
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:12 pmCHS - PTY
2 stops20h 30mAmerican Airlines
Sat 12/132:50 pmPTY - CHS
1 stop9h 56mAmerican Airlines
Deal found 10/24$394
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amCHS - PTY
1 stop9h 03mAmerican Airlines
Tue 11/252:43 pmPTY - CHS
2 stops17h 46mAmerican Airlines
Deal found 10/24$406
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:35 amCHS - PTY
1 stop8h 21mDelta
Wed 11/53:21 pmPTY - CHS
1 stop8h 38mDelta
Deal found 10/24$434
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:15 pmCHS - PTY
2 stops20h 48mAmerican Airlines
Wed 11/52:49 pmPTY - CHS
1 stop9h 10mAmerican Airlines
Deal found 10/24$438
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amCHS - PTY
1 stop7h 49mAmerican Airlines
Wed 11/122:49 pmPTY - CHS
1 stop17h 53mAmerican Airlines
Deal found 10/24$446
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:57 pmCHS - PTY
1 stop17h 52mAmerican Airlines
Tue 11/112:49 pmPTY - CHS
2 stops20h 46mAmerican Airlines
Deal found 10/25$447
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Sun 11/168:55 amPTY - CHS
1 stop13h 04mUnited Airlines
Deal found 10/24$454

Cheap flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$370
(Delta)

Popular in

March

Cheapest in

September

Average price

$463
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 12/9

6:30 am-2:21 pm

1 stop7h 51m

Panama City Tocumen Intl

Tue 12/16

3:46 pm-11:50 pm

1 stop8h 04m

$370

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 12/9

9:25 am-3:42 pm

1 stop6h 17m

Panama City Tocumen Intl

Tue 12/16

2:50 pm-11:25 am

2 stops20h 35m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 12/8

7:47 pm-3:42 pm

2 stops19h 55m

Panama City Tocumen Intl

Thu 12/11

2:50 pm-9:50 am

2 stops19h 00m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:25 pm-4:10 am

1 stop9h 45m

Panama City Tocumen Intl

Tue 3/17

10:55 pm-9:15 am

1 stop9h 20m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

10:59 am-7:02 pm

1 stop9h 03m

Panama City Tocumen Intl

Tue 3/24

10:55 pm-9:15 am

1 stop9h 20m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 12/8

5:05 pm-1:47 pm

2 stops20h 42m

Panama City Tocumen Intl

Sat 12/13

2:50 pm-8:38 am

2 stops17h 48m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

6:31 pm-12:10 pm

2 stops18h 39m

Panama City Tocumen Intl

Tue 3/17

3:50 pm-12:09 pm

2 stops19h 19m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Compare providers for flights from Charleston to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2025.

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 7% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 26, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,997 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    Delta, American Airlines, and United Airlines can get you from Charleston to Panama City in just under 6h 17m. Your travel time can differ by up to 3h 28m. The distance between Charleston and Panama City is about 1645 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $369. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $386 and $391, respectively. These flights start at 31% lower than the current average price 3 months from now.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Panama City

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Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$369Average$476FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$386Average$537FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$477FlexibilityNo cancel feeOn-time69%

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