$286+ Cheap flights from Charleston (CHS) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Nov 14 — Nov 211
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 15, 2026.
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:00 am -
1 stop13h 02m
Mon 12/78:55 am -
1 stop13h 04m
Deal found 10/13![United Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:21 am -
1 stop7h 13m
Wed 12/23:13 pm -
1 stop7h 00m
Deal found 10/11![American Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:52 pm -
2 stops23h 46m
Mon 11/168:55 am -
2 stops29h 01m
Deal found 10/12![United Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:45 am -
1 stop13h 17m
Tue 12/1511:35 am -
1 stop10h 24m
Deal found 10/13![United Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:00 am -
2 stops29h 34m
Thu 12/33:13 pm -
2 stops19h 17m
Deal found 10/12![American Airlines logo]()
$682
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 15, 2026.
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:00 am -
1 stop13h 02m
Thu 12/310:00 am -
1 stop13h 59m
Deal found 10/12![United Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/137:15 am -
1 stop6h 32m
Thu 2/182:47 pm -
1 stop9h 21m
Deal found 10/10![American Airlines logo]()
$681
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:34 am -
1 stop7h 28m
Mon 11/163:29 pm -
1 stop8h 30m
Deal found 10/12![Delta logo]()
$694
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:15 pm -
2 stops28h 57m
Mon 12/78:55 am -
2 stops26h 08m
Deal found 10/12![United Airlines logo]()
$671
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/36:05 am -
2 stops13h 32m
Thu 4/810:55 pm -
1 stop18h 11m
Deal found 10/10![United Airlines logo]()
$686
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:51 pm -
2 stops24h 11m
Tue 1/194:41 pm -
2 stops26h 27m
Deal found 10/13![United Airlines logo]()
$686
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/106:00 am -
1 stop14h 02m
Sun 2/148:55 am -
2 stops25h 00m
Deal found 10/13![United Airlines logo]()
$686
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/134:45 pm -
2 stops27h 17m
Thu 2/184:41 pm -
2 stops21h 17m
Deal found 10/10![United Airlines logo]()
$686
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated October 15, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated October 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:07 pm -
2 stops20h 06m
Thu 11/123:13 pm -
1 stop8h 46m
Deal found 10/11![American Airlines logo]()
$699
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:52 pm -
2 stops23h 46m
Mon 11/168:55 am -
2 stops29h 01m
Deal found 10/12![United Airlines logo]()
$676
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:34 am -
1 stop7h 28m
Mon 11/163:29 pm -
1 stop8h 30m
Deal found 10/12![Delta logo]()
$694
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:00 am -
2 stops29h 34m
Thu 12/33:13 pm -
2 stops19h 17m
Deal found 10/12![American Airlines logo]()
$682
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:21 am -
1 stop7h 13m
Wed 12/23:13 pm -
1 stop7h 00m
Deal found 10/11![American Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:16 pm -
2 stops22h 18m
Fri 12/43:13 pm -
2 stops18h 34m
Deal found 10/13![American Airlines logo]()
$712
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated October 15, 2026.
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop13h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Mon 2/226:56 pm -
2 stops18h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2210:59 am -
1 stop9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![United Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:00 am -
1 stop13h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:40 am -
3 stops47h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:45 am -
1 stop13h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:45 am -
3 stops25h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/224:22 pm -
3 stops42h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$496
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:27 pm -
3 stops34h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$855
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $647 (United Airlines) |
One-way from | $286 (United Airlines) |
Popular in | November |
Cheapest in | March |
Average price | $650 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 12/10
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 2/22
6:56 pm-1:47 pm
2 stops18h 51m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$291
Quickest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 2/22
10:59 am-8:02 pm
1 stop9h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Fri 12/11
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$320
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 12/10
6:45 am-7:49 am
3 stops25h 04m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$426
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 2/22
4:22 pm-10:40 am
3 stops42h 18m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$496
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 11/26
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Thu 12/3
10:00 am-11:59 pm
1 stop13h 59m
$659
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 12/2
12:15 pm-5:12 pm
2 stops28h 57m
Panama City Tocumen Intl
Mon 12/7
8:55 am-11:03 am
2 stops26h 08m
$671
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Sat 2/13
7:15 am-1:47 pm
1 stop6h 32m
Panama City Tocumen Intl
Thu 2/18
2:47 pm-12:08 am
1 stop9h 21m
$681
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Sat 4/3
6:05 am-6:37 pm
2 stops13h 32m
Panama City Tocumen Intl
Thu 4/8
10:55 pm-6:06 pm
1 stop18h 11m
$686
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
What is the cheapest month to book a flight from Charleston to Panama City?
Currently, March is the cheapest month in which you can book a flight from Charleston to Panama City (average of $487). Flying from Charleston to Panama City in November is currently the most expensive (average of $878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charleston to Panama City?
Airfare is typical for this route at the moment.
Charleston to Panama City flights typically cost between $510 and $793 in December.The cheapest round-trip price found within the last 5 days was $647 on United Airlines (Dec 2-Dec 7).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 15, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Panama City by cabin class
Find flights from Charleston to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Panama City flights
Browse other Charleston and Panama City flight options. Last updated on October 15, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on October 15, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Panama City
Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$690 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$369 | Average$644 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$458 | Average$650 | FlexibilityNo cancel fee | On-time71% |