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Panama City

$369+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
oct. 17 — oct. 241
ven. 10/17
ven. 10/24
1 adult, Economy
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Cheap flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 17, 2025.

Round-trip from

$369
(Delta)

Popular in

March

Cheapest in

November

Average price

$444
From Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/276:30 amCHS - PTY
1 stop13h 08mUnited Airlines
mar. 11/258:55 amPTY - CHS
1 stop13h 04mUnited Airlines
Deal found 9/14$369
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/35:39 pmCHS - PTY
2 stops20h 10mAmerican Airlines
ven. 11/72:49 pmPTY - CHS
2 stops17h 40mAmerican Airlines
Deal found 9/16$374
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/268:03 pmCHS - PTY
1 stop17h 53mDelta
lun. 11/243:37 pmPTY - CHS
1 stop7h 11mDelta
Deal found 9/14$376
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/306:30 amCHS - PTY
1 stop13h 08mUnited Airlines
jeu. 11/274:41 pmPTY - CHS
1 stop23h 35mUnited Airlines
Deal found 9/14$378
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 10/157:41 pmCHS - PTY
2 stops19h 22mAmerican Airlines
mer. 10/223:15 pmPTY - CHS
2 stops16h 01mAmerican Airlines
Deal found 9/16$382
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/275:35 amCHS - PTY
1 stop8h 21mDelta
sam. 11/223:37 pmPTY - CHS
1 stop8h 20mDelta
Deal found 9/14$389
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 10/296:30 amCHS - PTY
2 stops8h 33mAmerican Airlines
lun. 11/242:43 pmPTY - CHS
2 stops21h 12mAmerican Airlines
Deal found 9/14$394
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/268:03 pmCHS - PTY
1 stop17h 53mDelta
sam. 11/228:05 amPTY - CHS
1 stop7h 12mDelta
Deal found 9/14$396
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/27:57 pmCHS - PTY
1 stop17h 52mAmerican Airlines
ven. 11/72:49 pmPTY - CHS
1 stop9h 10mAmerican Airlines
Deal found 9/16$398
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/266:30 amCHS - PTY
1 stop13h 08mUnited Airlines
ven. 11/218:55 amPTY - CHS
1 stop13h 04mUnited Airlines
Deal found 9/14$409
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 10/316:30 amCHS - PTY
1 stop13h 08mUnited Airlines
lun. 11/248:55 amPTY - CHS
1 stop13h 04mUnited Airlines
Deal found 9/14$442

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 17, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mer. 10/29

6:40 am-12:56 pm

1 stop7h 16m

Panama City Tocumen Intl

jeu. 11/27

3:37 pm-10:48 pm

1 stop7h 11m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mer. 10/29

6:00 am-1:55 pm

1 stop8h 55m

Panama City Tocumen Intl

mar. 11/25

8:55 am-9:59 pm

1 stop13h 04m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mer. 10/29

6:40 am-12:56 pm

1 stop7h 16m

Panama City Tocumen Intl

lun. 11/24

3:37 pm-11:57 pm

1 stop8h 20m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

lun. 10/27

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

mar. 11/25

8:55 am-9:59 pm

1 stop13h 04m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 10/28

5:35 am-12:56 pm

1 stop8h 21m

Panama City Tocumen Intl

jeu. 11/27

3:37 pm-10:48 pm

1 stop7h 11m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

jeu. 10/30

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

mar. 11/25

8:55 am-9:59 pm

1 stop13h 04m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 10/28

5:35 am-12:56 pm

1 stop8h 21m

Panama City Tocumen Intl

mer. 11/26

3:37 pm-11:57 pm

1 stop8h 20m

$369

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

lun. 11/3

5:09 pm-1:49 pm

2 stops20h 40m

Panama City Tocumen Intl

ven. 11/7

2:49 pm-12:23 pm

2 stops21h 34m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 10/28

6:40 am-12:56 pm

1 stop7h 16m

Panama City Tocumen Intl

mar. 11/25

3:37 pm-9:31 am

1 stop17h 54m

$376

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

dim. 10/26

8:03 pm-12:56 pm

1 stop17h 53m

Panama City Tocumen Intl

jeu. 11/27

3:37 pm-10:48 pm

1 stop7h 11m

$376

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 12 results
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Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 17, 2025.

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 6% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated septembre 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    Delta and United Airlines can get you from Charleston to Panama City in just under 7h 16m. Your travel time can differ by up to 1h 39m. The distance between Charleston and Panama City is about 1645 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $361. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $369 and $391, respectively. These flights start at 33% lower than the current average price 3 months from now.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$361Average$537FlexibilityNo cancel feeOn-time71%
DeltaCheapest$369Average$476FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$391Average$477FlexibilityNo cancel feeOn-time69%

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