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Panama City

$178+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Mar 26 — Apr 21
Thu 3/26
Thu 4/2
1 adult, Economy
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Cheap flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.

This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:40 pm
CHS
-
PTY
1 stop9h 24m
United Airlines
Wed 4/227:55 am
PTY
-
CHS
1 stop13h 04m
United Airlines
Deal found 2/20$421
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:45 pm
CHS
-
PTY
2 stops18h 55m
American Airlines
Fri 4/31:50 pm
PTY
-
CHS
1 stop9h 09m
American Airlines
Deal found 2/23$425
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:20 pm
CHS
-
PTY
2 stops19h 26m
American Airlines
Thu 4/161:49 pm
PTY
-
CHS
2 stops17h 43m
American Airlines
Deal found 2/23$428
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:40 am
CHS
-
PTY
1 stop12h 57m
United Airlines
Thu 4/163:30 pm
PTY
-
CHS
1 stop29h 29m
United Airlines
Deal found 2/23$430
This BusinessClass deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:30 am
CHS
-
PTY
1 stop13h 32m
Copa Airlines
Mon 3/303:30 pm
PTY
-
CHS
1 stop23h 41m
Copa Airlines
Deal found 2/21$432
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:09 pm
CHS
-
PTY
1 stop17h 37m
American Airlines
Fri 4/171:49 pm
PTY
-
CHS
2 stops20h 50m
American Airlines
Deal found 2/24$434
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:40 am
CHS
-
PTY
1 stop12h 57m
United Airlines
Wed 4/157:55 am
PTY
-
CHS
1 stop13h 04m
United Airlines
Deal found 2/22$438
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:50 am
CHS
-
PTY
1 stop9h 30m
American Airlines
Mon 8/313:20 pm
PTY
-
CHS
2 stops21h 35m
American Airlines
Deal found 2/22$445
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:40 pm
CHS
-
PTY
1 stop9h 24m
United Airlines
Fri 4/1710:00 am
PTY
-
CHS
1 stop10h 59m
United Airlines
Deal found 2/24$447
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:15 pm
CHS
-
PTY
2 stops21h 21m
American Airlines
Sun 11/82:43 pm
PTY
-
CHS
2 stops21h 28m
American Airlines
Deal found 2/23$450

Find flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$421
(United Airlines)

One-way from

$178
(United Airlines)

Popular in

April

Cheapest in

September

Average price

$593
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama City Tocumen Intl
Search Deals
One-way flight from Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/15

6:00 am-4:12 pm

2 stops11h 12m

Panama City Tocumen Intl

Wed 4/22

10:00 am-9:59 pm

1 stop10h 59m

$421

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/18

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 6/22

7:55 am-10:15 pm

1 stop13h 20m

$421

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/28

11:18 am-7:31 pm

1 stop9h 13m

Panama City Tocumen Intl

Wed 6/3

7:55 am-10:15 pm

1 stop13h 20m

$421

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/28

4:13 pm-12:14 pm

2 stops21h 01m

Panama City Tocumen Intl

Wed 6/3

1:14 pm-11:40 am

2 stops21h 26m

$425

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/15

6:20 pm-12:46 pm

2 stops19h 26m

Panama City Tocumen Intl

Wed 4/22

1:49 pm-8:32 am

2 stops17h 43m

$428

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 4/9

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Thu 4/16

3:30 pm-9:59 pm

1 stop29h 29m

$430

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/8

6:40 am-6:37 pm

1 stop12h 57m

Panama City Tocumen Intl

Wed 4/15

7:55 am-9:59 pm

1 stop13h 04m

$438

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 5/15

7:50 pm-4:04 am

1 stop9h 14m

Panama City Tocumen Intl

Mon 5/25

10:00 am-10:15 pm

1 stop11h 15m

$441

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/1

6:40 am-6:37 pm

1 stop12h 57m

$178

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/1

6:45 pm-3:01 pm

2 stops21h 16m

$183

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 15 results
1
2

Compare providers for flights from Charleston to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $245). Flying from Charleston to Panama City in April is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Charleston to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 24, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,239 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,239 reviews
Delta
7.9
Good
8,239 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,344 reviews
Delta
7.9
Good
8,239 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,344 reviews
Delta
7.9
Good
8,239 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    United Airlines and American Airlines can get you from Charleston to Panama City in just under 11h 12m. Your travel time can differ by up to 9h 49m. The distance between Charleston and Panama City is about 1645 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $309. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $363 and $369, respectively. These flights start at 44% lower than the current average price 3 months from now.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $245). Flying from Charleston to Panama City in April is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$309Average$464FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$363Average$546FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$369Average$513FlexibilityNo cancel feeOn-time69%

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