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Panama City

$184+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:47 pmCHS - PTY
2 stops18h 00mAmerican Airlines
Mon 12/154:43 pmPTY - CHS
2 stops17h 07mAmerican Airlines
Deal found 11/10$414
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:46 pmCHS - PTY
2 stops22h 01mAmerican Airlines
Tue 12/232:53 pmPTY - CHS
2 stops19h 42mAmerican Airlines
Deal found 11/11$458
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amCHS - PTY
1 stop8h 15mUnited Airlines
Thu 12/2510:00 amPTY - CHS
1 stop9h 15mUnited Airlines
Deal found 11/11$473
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/169:25 amCHS - PTY
1 stop6h 17mAmerican Airlines
Wed 12/242:53 pmPTY - CHS
2 stops19h 48mAmerican Airlines
Deal found 11/11$477
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Wed 12/2411:55 pmPTY - CHS
1 stop9h 15mUnited Airlines
Deal found 11/11$493
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:30 amCHS - PTY
1 stop8h 15mUnited Airlines
Fri 12/268:55 amPTY - CHS
1 stop13h 02mUnited Airlines
Deal found 11/11$513
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Tue 12/2310:00 amPTY - CHS
1 stop9h 15mUnited Airlines
Deal found 11/11$530
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:00 amCHS - PTY
1 stop9h 42mAmerican Airlines
Tue 12/234:55 pmPTY - CHS
1 stop7h 42mAmerican Airlines
Deal found 11/11$532
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:00 amCHS - PTY
2 stops10h 42mAmerican Airlines
Thu 12/252:53 pmPTY - CHS
1 stop9h 44mAmerican Airlines
Deal found 11/11$536
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:46 pmCHS - PTY
2 stops22h 01mAmerican Airlines
Mon 12/224:55 pmPTY - CHS
1 stop7h 42mAmerican Airlines
Deal found 11/11$544
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:30 amCHS - PTY
1 stop8h 15mUnited Airlines
Thu 12/2510:00 amPTY - CHS
1 stop9h 15mUnited Airlines
Deal found 11/11$576

Cheap flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$370
(American Airlines)

Popular in

July

Cheapest in

September

Average price

$402
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 3/4

7:40 pm-3:14 pm

2 stops19h 34m

Panama City Tocumen Intl

Wed 3/11

1:50 pm-12:09 pm

2 stops21h 19m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

10:59 am-7:02 pm

1 stop9h 03m

Panama City Tocumen Intl

Tue 3/24

7:55 am-9:52 pm

1 stop12h 57m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/9

6:00 am-3:38 pm

1 stop9h 38m

Panama City Tocumen Intl

Sat 1/17

5:00 pm-11:58 pm

1 stop6h 58m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

6:31 pm-12:10 pm

2 stops18h 39m

Panama City Tocumen Intl

Tue 3/17

1:50 pm-10:59 am

2 stops20h 09m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

6:31 pm-12:10 pm

2 stops18h 39m

Panama City Tocumen Intl

Tue 3/24

1:50 pm-11:13 am

2 stops20h 23m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:25 pm-4:10 am

1 stop9h 45m

Panama City Tocumen Intl

Tue 3/17

3:41 pm-9:52 pm

1 stop29h 11m

$398

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 12/8

7:47 pm-1:47 pm

2 stops18h 00m

Panama City Tocumen Intl

Mon 12/15

4:43 pm-9:50 am

2 stops17h 07m

$414

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 12/3

5:05 pm-1:47 pm

2 stops20h 42m

$184

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 12/3

6:30 am-2:45 pm

1 stop8h 15m

$184

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 12/3

8:31 am-6:55 pm

3 stops34h 24m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 13 results
1
2

Compare providers for flights from Charleston to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 7% on airfare.

How much does it cost to fly round-trip from Charleston to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    American Airlines and United Airlines can get you from Charleston to Panama City in just under 9h 03m. Your travel time can differ by up to 10h 31m. The distance between Charleston and Panama City is about 1645 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $369. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $386 and $391, respectively. These flights start at 30% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Charleston to Panama City one-way?

    $184 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $184 and $603, respectively.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$369Average$476FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$386Average$533FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$477FlexibilityNo cancel feeOn-time69%

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