HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$152+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:15 amCHS - PTY
1 stop11h 45mDelta
Fri 12/268:00 amPTY - CHS
1 stop7h 08mDelta
Deal found 12/17$553
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:27 pmCHS - PTY
2 stops19h 26mAmerican Airlines
Fri 12/264:55 pmPTY - CHS
1 stop15h 52mAmerican Airlines
Deal found 12/17$588
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amCHS - PTY
1 stop8h 23mAmerican Airlines
Sun 12/282:53 pmPTY - CHS
1 stop9h 52mAmerican Airlines
Deal found 12/15$609
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Tue 1/64:41 pmPTY - CHS
1 stop23h 36mUnited Airlines
Deal found 12/16$669
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:08 pmCHS - PTY
2 stops19h 46mAmerican Airlines
Tue 1/64:31 pmPTY - CHS
2 stops21h 03mAmerican Airlines
Deal found 12/18$737

Find flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$374
(American Airlines)

One-way from

$152
(United Airlines)

Popular in

April

Cheapest in

September

Average price

$682
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
Search Deals
From Charleston to Panama City Tocumen Intl
Search Deals
One-way flight from Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/30

6:10 am-3:38 pm

2 stops9h 28m

Panama City Tocumen Intl

Fri 2/6

2:27 pm-9:48 am

2 stops19h 21m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 1/26

11:00 am-8:02 pm

1 stop9h 02m

Panama City Tocumen Intl

Thu 1/29

11:35 am-4:17 pm

1 stop28h 42m

$378

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:02 pm-2:22 pm

2 stops20h 20m

Panama City Tocumen Intl

Tue 3/17

3:13 pm-11:59 pm

1 stop7h 46m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 1/7

9:27 am-3:31 pm

1 stop6h 04m

Panama City Tocumen Intl

Fri 1/23

4:50 pm-11:58 pm

1 stop7h 08m

$402

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

6:37 pm-12:40 pm

2 stops19h 03m

Panama City Tocumen Intl

Sat 3/21

1:44 pm-10:17 am

2 stops19h 33m

$414

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/30

10:55 am-8:02 pm

1 stop9h 07m

Panama City Tocumen Intl

Fri 2/6

4:41 pm-4:20 pm

1 stop23h 39m

$418

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/16

5:41 pm-3:52 pm

2 stops22h 11m

Panama City Tocumen Intl

Sun 2/1

4:50 pm-8:47 am

1 stop15h 57m

$419

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 1/26

11:00 am-8:02 pm

1 stop9h 02m

$152

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 2/2

5:41 pm-1:27 pm

2 stops19h 46m

$152

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 2/2

11:00 am-8:02 pm

1 stop9h 02m

$152

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 13 results
1
2

Compare providers for flights from Charleston to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 7% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    American Airlines and United Airlines can get you from Charleston to Panama City in just under 9h 02m. Your travel time can differ by up to 26m. The distance between Charleston and Panama City is about 1645 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $349. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $363 and $369, respectively. These flights start at 35% lower than the current average price 3 months from now.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama City (average of $230). Flying from Charleston to Panama City in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Panama City flights
Myrtle Beach to Panama City flights
Greenville to Panama City flights
Columbia to Panama City flights
Savannah to Panama City flights
Augusta to Panama City flights

Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$469FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$363Average$523FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$369Average$473FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.