HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$374+ Cheap flights from Charleston (CHS) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
août 23 — août 301
sam. 8/23
sam. 8/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated août 18, 2025.

Round-trip from

$374
(American Airlines)

Popular in

March

Cheapest in

November

Average price

$456
From Charleston to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/207:54 pmCHS - PTY
2 stops19h 09mAmerican Airlines
lun. 10/273:15 pmPTY - CHS
2 stops19h 20mAmerican Airlines
Deal found 8/17$394
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 9/176:00 amCHS - PTY
1 stop8h 50mUnited Airlines
sam. 9/203:30 pmPTY - CHS
1 stop24h 05mUnited Airlines
Deal found 8/17$398
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 9/176:16 pmCHS - PTY
2 stops21h 15mAmerican Airlines
dim. 9/213:31 pmPTY - CHS
2 stops26h 11mAmerican Airlines
Deal found 8/17$399
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/199:42 amCHS - PTY
1 stop5h 21mAmerican Airlines
lun. 10/273:15 pmPTY - CHS
1 stop16h 46mAmerican Airlines
Deal found 8/17$409
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 10/1010:37 amCHS - PTY
1 stop28h 26mAmerican Airlines
lun. 10/133:15 pmPTY - CHS
2 stops17h 16mAmerican Airlines
Deal found 8/17$422
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/15:30 amCHS - PTY
1 stop8h 22mDelta
sam. 12/138:05 amPTY - CHS
1 stop15h 36mDelta
Deal found 8/17$426
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 9/105:37 pmCHS - PTY
2 stops21h 54mAmerican Airlines
dim. 9/143:31 pmPTY - CHS
2 stops24h 14mAmerican Airlines
Deal found 8/16$431
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/226:00 amCHS - PTY
2 stops9h 30mAmerican Airlines
ven. 8/293:30 pmPTY - CHS
2 stops26h 35mAmerican Airlines
Deal found 8/17$438
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 9/105:16 pmCHS - PTY
1 stop21h 58mUnited Airlines
dim. 9/143:30 pmPTY - CHS
1 stop24h 05mUnited Airlines
Deal found 8/17$439

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated août 18, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

jeu. 1/8

7:46 pm-1:10 pm

2 stops17h 24m

Panama City Tocumen Intl

ven. 1/30

2:45 pm-11:12 pm

1 stop8h 27m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

lun. 12/1

4:59 pm-1:36 pm

2 stops20h 37m

Panama City Tocumen Intl

sam. 12/13

2:45 pm-8:31 am

2 stops17h 46m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mer. 9/17

5:37 pm-2:31 pm

2 stops21h 54m

Panama City Tocumen Intl

sam. 9/20

3:31 pm-11:19 am

2 stops18h 48m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

lun. 10/20

7:54 pm-2:03 pm

2 stops19h 09m

Panama City Tocumen Intl

lun. 10/27

3:15 pm-11:35 am

2 stops19h 20m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PTY?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated août 18, 2025.

One of the essential ways to save on airfare from Charleston to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 6% on airfare.

How much does it cost to fly round-trip from Charleston to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated août 18, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City?

    American Airlines can get you from Charleston to Panama City in just under 17h 24m. Your travel time can differ by up to . The distance between Charleston and Panama City is about 1645 mi.

  • What are the cheapest airlines flying from Charleston to Panama City round-trip?

    Flying on Delta is currently your cheapest option to Panama City, with prices starting at $349. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $361 and $391, respectively. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Panama City (average of $478). Flying from Charleston to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Panama City flights
Columbia to Panama City flights
Greenville to Panama City flights
Augusta to Panama City flights
Myrtle Beach to Panama City flights
Savannah to Panama City flights

Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated août 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$476FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$361Average$539FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$476FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.