$276+ Cheap flights from Charleston (CHS) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:40 am -
2 stops18h 30m
Sat 12/123:55 pm -
2 stops19h 57m
Deal found 8/28![Multiple Airlines logo]()
$582
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:40 am -
3 stops31h 20m
Sat 12/125:30 am -
2 stops16h 51m
Deal found 8/28![Multiple Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop13h 08m
Tue 11/310:00 am -
1 stop13h 59m
Deal found 8/28![United Airlines logo]()
$597
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:43 pm -
2 stops14h 47m
Fri 10/233:50 pm -
2 stops17h 25m
Deal found 9/1![Multiple Airlines logo]()
$600
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:08 am -
2 stops24h 22m
Tue 9/293:50 pm -
2 stops17h 27m
Deal found 8/28![Multiple Airlines logo]()
$608
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:04 pm -
2 stops18h 58m
Tue 11/33:13 pm -
2 stops20h 11m
Deal found 9/1![American Airlines logo]()
$611
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am -
1 stop8h 29m
Mon 10/192:24 pm -
1 stop8h 35m
Deal found 8/28![Delta logo]()
$619
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop8h 02m
Fri 10/232:02 pm -
1 stop8h 57m
Deal found 9/1![American Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
1 stop13h 02m
Tue 11/2410:00 am -
1 stop13h 59m
Deal found 8/28![United Airlines logo]()
$631
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1410:10 am -
2 stops16h 00m
Tue 1/193:55 pm -
2 stops17h 25m
Deal found 9/1![Multiple Airlines logo]()
$582
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop13h 08m
Tue 11/310:00 am -
1 stop13h 59m
Deal found 8/28![United Airlines logo]()
$597
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop7h 59m
Mon 11/93:29 pm -
1 stop8h 30m
Deal found 8/29![Delta logo]()
$597
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:30 pm -
2 stops21h 06m
Thu 1/284:55 pm -
1 stop16h 59m
Deal found 8/30![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:04 pm -
2 stops18h 58m
Tue 11/33:13 pm -
2 stops20h 11m
Deal found 9/1![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
1 stop13h 02m
Tue 11/2410:00 am -
1 stop13h 59m
Deal found 8/28![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:19 pm -
2 stops24h 19m
Mon 11/98:55 am -
1 stop13h 04m
Deal found 8/29![United Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
1 stop13h 02m
Sat 12/128:55 am -
1 stop12h 59m
Deal found 8/28![United Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 pm -
2 stops21h 45m
Sat 12/1210:00 am -
1 stop13h 59m
Deal found 9/1![United Airlines logo]()
$669
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated September 2, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:08 am -
2 stops24h 22m
Tue 9/293:50 pm -
2 stops17h 27m
Deal found 8/28![Multiple Airlines logo]()
$608
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
1 stop13h 31m
Wed 10/79:45 am -
1 stop13h 14m
Deal found 9/1![United Airlines logo]()
$641
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am -
1 stop8h 29m
Mon 10/192:24 pm -
1 stop8h 35m
Deal found 8/28![Delta logo]()
$619
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:04 pm -
2 stops18h 58m
Mon 10/192:02 pm -
2 stops25h 42m
Deal found 8/28![American Airlines logo]()
$657
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:43 pm -
2 stops14h 47m
Fri 10/233:50 pm -
2 stops17h 25m
Deal found 9/1![Multiple Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop8h 02m
Fri 10/232:02 pm -
1 stop8h 57m
Deal found 9/1![American Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop13h 08m
Tue 11/310:00 am -
1 stop13h 59m
Deal found 8/28![United Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:04 pm -
2 stops18h 58m
Tue 11/33:13 pm -
2 stops20h 11m
Deal found 9/1![American Airlines logo]()
$611
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:43 pm -
2 stops14h 47m
Deal found 8/29![Multiple Airlines logo]()
$276
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:40 am -
2 stops26h 55m
Deal found 8/29![Multiple Airlines logo]()
$282
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
1 stop8h 02m
Deal found 8/29![American Airlines logo]()
$288
This KAYAK deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
2 stops13h 38m
Deal found 8/29![Copa Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:00 am -
1 stop7h 13m
Deal found 9/1![American Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1310:05 pm -
1 stop22h 14m
Deal found 8/29![Multiple Airlines logo]()
$417
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $582 (Expedia) |
One-way from | $276 (Expedia) |
Popular in | April |
Cheapest in | March |
Average price | $608 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 1/14
10:10 am-2:10 am
2 stops16h 00m
Panama City Tocumen Intl
Tue 1/19
3:55 pm-9:20 am
2 stops17h 25m
$582
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 10/29
6:30 am-6:38 pm
1 stop13h 08m
Panama City Tocumen Intl
Tue 11/3
10:00 am-11:59 pm
1 stop13h 59m
$597
Quickest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 11/5
6:00 am-1:59 pm
1 stop7h 59m
Panama City Tocumen Intl
Mon 11/9
3:29 pm-11:59 pm
1 stop8h 30m
$597
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 1/20
4:30 pm-1:36 pm
2 stops21h 06m
Panama City Tocumen Intl
Thu 1/28
4:55 pm-9:54 am
1 stop16h 59m
$606
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 10/29
7:04 pm-1:02 pm
2 stops18h 58m
Panama City Tocumen Intl
Tue 11/3
3:13 pm-11:24 am
2 stops20h 11m
$611
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Fri 11/20
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Tue 11/24
10:00 am-11:59 pm
1 stop13h 59m
$631
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 11/5
7:19 pm-7:38 pm
2 stops24h 19m
Panama City Tocumen Intl
Mon 11/9
8:55 am-9:59 pm
1 stop13h 04m
$635
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Fri 12/4
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Sat 12/12
8:55 am-9:54 pm
1 stop12h 59m
$665
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Sat 12/5
5:00 pm-2:45 pm
2 stops21h 45m
Panama City Tocumen Intl
Sat 12/12
10:00 am-11:59 pm
1 stop13h 59m
$669
Cheapest one-way
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Sat 12/12
7:40 am-10:35 am
2 stops26h 55m
$282
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 2, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for Charleston to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Panama City by cabin class
Find flights from Charleston to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Panama City flights
Browse other Charleston and Panama City flight options. Last updated on September 2, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Panama City
Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$612 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$369 | Average$630 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$399 | Average$629 | FlexibilityNo cancel fee | On-time71% |