$266+ Cheap flights from Charleston (CHS) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Sep 12 — Sep 191
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to Panama CityExplore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 pm -
2 stops15h 05m
Sun 11/111:25 am -
3 stops22h 34m
Deal found 8/9![Multiple Airlines logo]()
$559
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:25 pm -
3 stops18h 30m
Sun 11/811:25 am -
3 stops22h 34m
Deal found 8/10![Multiple Airlines logo]()
$566
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
2 stops15h 05m
Sat 10/317:50 pm -
2 stops38h 09m
Deal found 8/9![Multiple Airlines logo]()
$569
This Orbitz deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:08 am -
2 stops24h 22m
Sun 9/273:50 pm -
2 stops17h 27m
Deal found 8/9![Multiple Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops14h 31m
Mon 10/53:30 pm -
2 stops17h 57m
Deal found 8/10![United Airlines logo]()
$601
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:14 pm -
2 stops15h 16m
Sun 9/133:50 pm -
2 stops17h 27m
Deal found 8/10![Multiple Airlines logo]()
$608
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:10 am -
1 stop9h 21m
Wed 9/309:45 am -
1 stop13h 14m
Deal found 8/9![United Airlines logo]()
$609
This Travelocity deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:25 pm -
2 stops14h 05m
Mon 11/97:50 pm -
2 stops14h 09m
Deal found 8/10![Multiple Airlines logo]()
$611
Best flights from Charleston to Panama CityDiscover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
Discover carefully curated flight deals from Charleston to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
This Expedia deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2010:10 am -
3 stops28h 45m
Wed 1/273:50 pm -
2 stops17h 30m
Deal found 8/11![Multiple Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am -
1 stop13h 31m
Mon 10/53:30 pm -
2 stops21h 34m
Deal found 8/8![United Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
1 stop7h 27m
Wed 1/274:46 pm -
1 stop7h 09m
Deal found 8/11![American Airlines logo]()
$602
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:50 am -
1 stop6h 08m
Wed 9/232:23 pm -
1 stop8h 36m
Deal found 8/12![Delta logo]()
$621
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:55 am -
2 stops26h 50m
Wed 1/278:55 am -
1 stop12h 59m
Deal found 8/10![United Airlines logo]()
$601
This Expedia deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:08 am -
2 stops24h 22m
Mon 9/213:50 pm -
2 stops17h 27m
Deal found 8/8![Multiple Airlines logo]()
$616
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:00 am -
1 stop13h 31m
Wed 9/303:30 pm -
2 stops21h 34m
Deal found 8/9![United Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop12h 37m
Thu 9/1710:00 am -
2 stops23h 37m
Deal found 8/10![United Airlines logo]()
$625
Last-minute flights from Charleston to Panama CityDiscover last-minute flight deals from Charleston to Panama City. Data last updated August 13, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Panama City. Data last updated August 13, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:14 pm -
2 stops15h 16m
Sun 9/133:50 pm -
2 stops17h 27m
Deal found 8/10![Multiple Airlines logo]()
$608
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop12h 37m
Thu 9/1710:00 am -
2 stops23h 37m
Deal found 8/10![United Airlines logo]()
$625
This Expedia deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:08 am -
2 stops24h 22m
Mon 9/213:50 pm -
2 stops17h 27m
Deal found 8/8![Multiple Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:50 am -
1 stop6h 08m
Wed 9/232:23 pm -
1 stop8h 36m
Deal found 8/12![Delta logo]()
$621
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:52 pm -
1 stop19h 06m
Wed 9/232:23 pm -
1 stop8h 36m
Deal found 8/12![Delta logo]()
$628
This Orbitz deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:08 am -
2 stops24h 22m
Sun 9/273:50 pm -
2 stops17h 27m
Deal found 8/9![Multiple Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:10 am -
1 stop9h 21m
Wed 9/309:45 am -
1 stop13h 14m
Deal found 8/9![United Airlines logo]()
$609
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:08 am -
3 stops28h 47m
Wed 9/303:50 pm -
2 stops17h 27m
Deal found 8/9![Multiple Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am -
1 stop12h 37m
Thu 10/13:30 pm -
1 stop29h 51m
Deal found 8/10![United Airlines logo]()
$620
One-way flights from Charleston to Panama CitySearch for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
Search for one-way flight options from Charleston to Panama City. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:02 pm -
2 stops17h 49m
Deal found 8/12![American Airlines logo]()
$266
This Orbitz deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:50 am -
2 stops24h 40m
Deal found 8/12![Multiple Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:00 am -
1 stop14h 02m
Deal found 8/12![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:02 am -
1 stop6h 57m
Deal found 8/12![Delta logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:59 pm -
1 stop21h 06m
Deal found 8/8![Multiple Airlines logo]()
$401
Find flight deals from Charleston to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $559 (Expedia) |
One-way from | $266 (American Airlines) |
Popular in | April |
Cheapest in | March |
Average price | $616 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 1/20
10:10 am-2:55 pm
3 stops28h 45m
Panama City Tocumen Intl
Wed 1/27
3:50 pm-9:20 am
2 stops17h 30m
$567
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 10/1
7:00 am-7:31 pm
1 stop13h 31m
Panama City Tocumen Intl
Mon 10/5
3:30 pm-2:04 pm
2 stops21h 34m
$601
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 1/20
11:55 am-2:45 pm
2 stops26h 50m
Panama City Tocumen Intl
Wed 1/27
8:55 am-9:54 pm
1 stop12h 59m
$601
Quickest round-trip
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 1/20
6:00 am-1:27 pm
1 stop7h 27m
Panama City Tocumen Intl
Wed 1/27
4:46 pm-11:55 pm
1 stop7h 09m
$602
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 9/23
7:00 am-7:31 pm
1 stop13h 31m
Panama City Tocumen Intl
Wed 9/30
3:30 pm-2:04 pm
2 stops21h 34m
$613
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 9/16
11:08 am-10:30 am
2 stops24h 22m
Panama City Tocumen Intl
Mon 9/21
3:50 pm-10:17 am
2 stops17h 27m
$616
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Wed 9/16
7:50 am-12:58 pm
1 stop6h 08m
Panama City Tocumen Intl
Wed 9/23
2:23 pm-11:59 pm
1 stop8h 36m
$621
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Thu 9/10
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Thu 9/17
10:00 am-10:37 am
2 stops23h 37m
$625
Cheapest one-way
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 1/4
8:02 pm-1:51 pm
2 stops17h 49m
$266
CharlestonPanama City
CHS Charleston - PTY Panama City Tocumen Intl
CHSPTY
Charleston
Mon 1/4
6:00 am-8:02 pm
1 stop14h 02m
$276
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Charleston to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
CHS-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Panama City
What is the cheapest month to book a flight from Charleston to Panama City?
Currently, March is the cheapest month in which you can book a flight from Charleston to Panama City (average of $487). Flying from Charleston to Panama City in April is currently the most expensive (average of $809). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charleston to Panama City?
Airfare is typical for this route at the moment.
Charleston to Panama City flights typically cost between $488 and $750 in October.The cheapest round-trip price found within the last 5 days was $559 on Multiple Airlines (Oct 22-Nov 1).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 13, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charleston to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Charleston to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Panama City by cabin class
Find flights from Charleston to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Panama City flights
Browse other Charleston and Panama City flight options. Last updated on August 13, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Panama City
Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$363 | Average$551 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$369 | Average$615 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$390 | Average$612 | FlexibilityNo cancel fee | On-timeN/A |