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Panama City

$595+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Aug 13 — Aug 201
Thu 8/13
Thu 8/20
1 adult, Economy
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Cheap flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.

This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:14 pm
GPT
-
PTY
1 stop21h 00m
United Airlines
Thu 10/110:00 am
PTY
-
GPT
1 stop9h 38m
United Airlines
Deal found 7/9$595
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:08 am
GPT
-
PTY
1 stop11h 29m
United Airlines
Wed 8/2610:00 am
PTY
-
GPT
1 stop9h 38m
United Airlines
Deal found 7/13$627
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:50 pm
GPT
-
PTY
2 stops22h 49m
American Airlines
Wed 8/261:39 pm
PTY
-
GPT
2 stops21h 02m
American Airlines
Deal found 7/9$631
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:00 pm
GPT
-
PTY
1 stop24h 14m
United Airlines
Mon 9/213:30 pm
PTY
-
GPT
1 stop24h 42m
United Airlines
Deal found 7/13$634
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:36 pm
GPT
-
PTY
2 stops19h 18m
American Airlines
Mon 1/114:46 pm
PTY
-
GPT
2 stops20h 46m
American Airlines
Deal found 7/11$671
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:00 am
GPT
-
PTY
1 stop13h 00m
Delta
Mon 1/113:20 pm
PTY
-
GPT
1 stop7h 47m
Delta
Deal found 7/11$880
This KAYAK deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:59 pm
GPT
-
PTY
1 stop25h 38m
Copa Airlines
Wed 8/267:24 am
PTY
-
GPT
2 stops12h 14m
Copa Airlines
Deal found 7/9$1,196

Find flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated July 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$595
(United Airlines)

Popular in

December

Cheapest in

February
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 9/27

5:14 pm-2:14 pm

1 stop21h 00m

Panama City Tocumen Intl

Thu 10/1

10:00 am-7:38 pm

1 stop9h 38m

$595

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 8/24

7:08 am-6:37 pm

1 stop11h 29m

Panama City Tocumen Intl

Wed 8/26

10:00 am-7:38 pm

1 stop9h 38m

$627

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 8/24

1:50 pm-12:39 pm

2 stops22h 49m

Panama City Tocumen Intl

Wed 8/26

1:39 pm-10:41 am

2 stops21h 02m

$631

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 9/18

2:00 pm-2:14 pm

1 stop24h 14m

Panama City Tocumen Intl

Mon 9/21

3:30 pm-4:12 pm

1 stop24h 42m

$634

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 12/31

7:36 pm-3:54 pm

2 stops19h 18m

Panama City Tocumen Intl

Mon 1/11

4:46 pm-12:32 pm

2 stops20h 46m

$671
Quickest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 12/31

6:00 am-8:00 pm

1 stop13h 00m

Panama City Tocumen Intl

Mon 1/11

3:20 pm-10:07 pm

1 stop7h 47m

$880

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/11

Sorted by cheapest first

Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines can get you from Biloxi to Panama City in just under 21h. Your travel time can differ by up to . There are 1600 mi between Biloxi and Panama City.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$691FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$546FlexibilityNo cancel feeOn-time69%
DeltaCheapest$391Average$620FlexibilityNo cancel feeOn-timeN/A

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