$447+ Cheap flights from Biloxi, MS to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Biloxi to Panama CityExplore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/7![United Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:08 am -
1 stop11h 29m
Sun 11/14:41 pm -
1 stop21h 37m
Deal found 9/9![United Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:42 pm -
2 stops18h 34m
Wed 10/72:02 pm -
2 stops21h 11m
Deal found 9/9![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:00 pm -
1 stop6h 37m
Wed 10/73:30 pm -
1 stop19h 48m
Deal found 9/9![United Airlines logo]()
$728
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:49 pm -
2 stops24h 13m
Sun 11/83:13 pm -
2 stops23h 05m
Deal found 9/7![American Airlines logo]()
$729
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:39 pm -
2 stops19h 23m
Mon 10/122:02 pm -
2 stops21h 11m
Deal found 9/7![American Airlines logo]()
$762
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:47 am -
2 stops25h 15m
Sun 11/13:13 pm -
2 stops27h 33m
Deal found 9/9![American Airlines logo]()
$786
Best flights from Biloxi to Panama CityDiscover carefully curated flight deals from Biloxi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Biloxi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/8![United Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:42 pm -
2 stops18h 34m
Wed 10/72:02 pm -
2 stops21h 11m
Deal found 9/9![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:08 am -
1 stop11h 29m
Sun 11/14:41 pm -
1 stop21h 37m
Deal found 9/9![United Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:49 pm -
2 stops24h 13m
Sun 11/83:13 pm -
2 stops23h 05m
Deal found 9/8![American Airlines logo]()
$733
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:00 pm -
1 stop6h 37m
Wed 10/73:30 pm -
1 stop19h 48m
Deal found 9/9![United Airlines logo]()
$728
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:39 pm -
2 stops19h 23m
Mon 10/122:02 pm -
2 stops21h 11m
Deal found 9/7![American Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:08 am -
1 stop11h 29m
Mon 10/123:30 pm -
1 stop28h 08m
Deal found 9/7![United Airlines logo]()
$728
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:47 am -
2 stops25h 15m
Sun 11/13:13 pm -
2 stops27h 33m
Deal found 9/9![American Airlines logo]()
$786
Last-minute flights from Biloxi to Panama CityDiscover last-minute flight deals from Biloxi to Panama City. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Biloxi to Panama City. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:42 pm -
2 stops18h 34m
Wed 10/72:02 pm -
2 stops21h 11m
Deal found 9/9![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:00 pm -
1 stop6h 37m
Wed 10/73:30 pm -
1 stop19h 48m
Deal found 9/9![United Airlines logo]()
$728
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:39 pm -
2 stops19h 23m
Mon 10/122:02 pm -
2 stops21h 11m
Deal found 9/7![American Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:08 am -
1 stop11h 29m
Sun 11/14:41 pm -
1 stop21h 37m
Deal found 9/9![United Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:47 am -
2 stops25h 15m
Sun 11/13:13 pm -
2 stops27h 33m
Deal found 9/9![American Airlines logo]()
$786
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/7![United Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:49 pm -
2 stops24h 13m
Sun 11/83:13 pm -
2 stops23h 05m
Deal found 9/7![American Airlines logo]()
$729
One-way flights from Biloxi to Panama CitySearch for one-way flight options from Biloxi to Panama City. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Biloxi to Panama City. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:42 pm -
2 stops18h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:25 am -
1 stop6h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:59 pm -
3 stops41h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$831
Find flight deals from Biloxi to Panama City
Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $648 (United Airlines) |
One-way from | $447 (American Airlines) |
Popular in | December |
Cheapest in | February |
Cheapflights Fare Finder
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 9/29
5:42 pm-12:26 pm
2 stops18h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$447
Quickest round-trip
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 9/29
6:25 am-12:58 pm
1 stop6h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$452
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Fri 10/30
4:55 pm-1:45 pm
1 stop20h 50m
Panama City Tocumen Intl
Sun 11/8
8:55 am-4:08 pm
1 stop8h 13m
$648
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Fri 10/23
7:08 am-6:37 pm
1 stop11h 29m
Panama City Tocumen Intl
Sun 11/1
4:41 pm-1:18 pm
1 stop21h 37m
$665
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Thu 10/1
5:42 pm-12:16 pm
2 stops18h 34m
Panama City Tocumen Intl
Wed 10/7
2:02 pm-11:13 am
2 stops21h 11m
$723
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Thu 10/1
12:00 pm-6:37 pm
1 stop6h 37m
Panama City Tocumen Intl
Wed 10/7
3:30 pm-11:18 am
1 stop19h 48m
$728
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 10/6
7:08 am-6:37 pm
1 stop11h 29m
Panama City Tocumen Intl
Mon 10/12
3:30 pm-7:38 pm
1 stop28h 08m
$728
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Fri 10/30
12:49 pm-1:02 pm
2 stops24h 13m
Panama City Tocumen Intl
Sun 11/8
3:13 pm-1:18 pm
2 stops23h 05m
$733
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 10/6
5:39 pm-1:02 pm
2 stops19h 23m
Panama City Tocumen Intl
Mon 10/12
2:02 pm-11:13 am
2 stops21h 11m
$762
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Fri 10/23
11:47 am-1:02 pm
2 stops25h 15m
Panama City Tocumen Intl
Sun 11/1
3:13 pm-5:46 pm
2 stops27h 33m
$786
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Biloxi to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
GPT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Biloxi to Panama City
B1L-PTY
GPT-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 12, 2026.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Overall
7.4
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Overall
7.4
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Biloxi to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Biloxi to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Biloxi and Panama City flights
Browse other Biloxi and Panama City flight options. Last updated on September 12, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Biloxi to Panama City flights
Consider these flights traveling from Biloxi to Panama City.
Top 4 airlines flying from Biloxi to Panama City
Discover the top 4 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$385 | Average$691 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$391 | Average$681 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$419 | Average$770 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$494 | Average$688 | FlexibilityNo cancel fee | On-timeN/A |