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Panama City

$492+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated September 16, 2025.

Round-trip from

$492
(American Airlines)

Popular in

September

Cheapest in

April

Average price

$885
From Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:06 pmGPT - PTY
2 stops18h 57mAmerican Airlines
Thu 11/62:49 pmPTY - GPT
2 stops27h 51mAmerican Airlines
Deal found 9/15$492
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:05 amGPT - PTY
1 stop6h 40mUnited Airlines
Thu 11/68:55 amPTY - GPT
1 stop8h 07mUnited Airlines
Deal found 9/14$506
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/122:00 pmGPT - PTY
1 stop28h 37mUnited Airlines
Sun 10/193:30 pmPTY - GPT
1 stop19h 36mUnited Airlines
Deal found 9/14$562
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/127:06 pmGPT - PTY
2 stops18h 57mAmerican Airlines
Sun 10/193:15 pmPTY - GPT
2 stops26h 33mAmerican Airlines
Deal found 9/15$577
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:05 amGPT - PTY
1 stop7h 09mUnited Airlines
Wed 10/13:30 pmPTY - GPT
1 stop19h 36mUnited Airlines
Deal found 9/13$585
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:32 pmGPT - PTY
2 stops19h 23mAmerican Airlines
Wed 10/11:45 pmPTY - GPT
2 stops22h 37mAmerican Airlines
Deal found 9/13$636
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 amGPT - PTY
1 stop6h 56mDelta
Thu 11/63:21 pmPTY - GPT
1 stop7h 29mDelta
Deal found 9/15$687
This United deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:05 amGPT - PTY
2 stops27h 20mMultiple Airlines
Wed 10/13:30 pmPTY - GPT
1 stop21h 55mMultiple Airlines
Deal found 9/13$852
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:55 pmGPT - PTY
2 stops28h 45mMultiple Airlines
Thu 11/611:38 amPTY - GPT
1 stop22h 21mMultiple Airlines
Deal found 9/15$915

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Biloxi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 10/30

7:06 pm-2:03 pm

2 stops18h 57m

Panama City Tocumen Intl

Thu 11/6

2:49 pm-5:40 pm

2 stops27h 51m

$492

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 10/30

7:05 am-1:45 pm

1 stop6h 40m

Panama City Tocumen Intl

Thu 11/6

8:55 am-4:02 pm

1 stop8h 07m

$506

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 10/12

2:00 pm-6:37 pm

1 stop28h 37m

Panama City Tocumen Intl

Sun 10/19

3:30 pm-11:06 am

1 stop19h 36m

$562

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 10/12

7:06 pm-2:03 pm

2 stops18h 57m

Panama City Tocumen Intl

Sun 10/19

3:15 pm-5:48 pm

2 stops26h 33m

$577

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 10/30

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Thu 11/6

3:21 pm-9:50 pm

1 stop7h 29m

$687

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 10/30

7:55 pm-12:40 am

2 stops28h 45m

Panama City Tocumen Intl

Thu 11/6

11:38 am-8:59 am

1 stop22h 21m

$915

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, October is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $478). Flying from Biloxi to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to PTY?

Find hourly flight availability from Biloxi to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Biloxi to Panama City as you normally would.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    American Airlines and United Airlines can get you from Biloxi to Panama City in just under 6h 40m. Your travel time can differ by up to 12h 17m. There are 1600 mi between Biloxi and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $478). Flying from Biloxi to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$382Average$552FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$402Average$551FlexibilityNo cancel feeOn-time71%
DeltaCheapest$411Average$523FlexibilityNo cancel feeOn-timeN/A

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