HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$535+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Biloxi to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:15 am
GPT
-
PTY
1 stop11h 22m
United Airlines
Wed 8/263:30 pm
PTY
-
GPT
1 stop28h 12m
United Airlines
Deal found 3/19$535
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:09 pm
GPT
-
PTY
2 stops18h 37m
American Airlines
Wed 5/61:49 pm
PTY
-
GPT
2 stops20h 44m
American Airlines
Deal found 3/15$551
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:05 pm
GPT
-
PTY
1 stop26h 07m
United Airlines
Wed 5/610:00 am
PTY
-
GPT
1 stop9h 53m
United Airlines
Deal found 3/15$575
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:05 pm
GPT
-
PTY
1 stop28h 32m
United Airlines
Thu 4/167:55 am
PTY
-
GPT
1 stop8h 18m
United Airlines
Deal found 3/17$615
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:05 pm
GPT
-
PTY
1 stop28h 32m
United Airlines
Sun 5/103:30 pm
PTY
-
GPT
1 stop28h 23m
United Airlines
Deal found 3/15$623
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:00 am
GPT
-
PTY
1 stop11h 38m
United Airlines
Thu 4/167:55 am
PTY
-
GPT
1 stop8h 18m
United Airlines
Deal found 3/17$637
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:29 pm
GPT
-
PTY
2 stops21h 51m
American Airlines
Thu 4/161:49 pm
PTY
-
GPT
2 stops27h 44m
American Airlines
Deal found 3/17$640
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:04 pm
GPT
-
PTY
2 stops23h 36m
American Airlines
Thu 4/161:49 pm
PTY
-
GPT
2 stops27h 44m
American Airlines
Deal found 3/17$680
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:00 am
GPT
-
PTY
1 stop9h 07m
United Airlines
Tue 4/143:30 pm
PTY
-
GPT
1 stop28h 23m
United Airlines
Deal found 3/18$685
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:09 pm
GPT
-
PTY
2 stops18h 37m
American Airlines
Sun 5/101:49 pm
PTY
-
GPT
2 stops20h 44m
American Airlines
Deal found 3/15$686
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:36 pm
GPT
-
PTY
2 stops19h 25m
American Airlines
Mon 4/61:40 pm
PTY
-
GPT
2 stops20h 53m
American Airlines
Deal found 3/19$691

Find flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$535
(United Airlines)

Popular in

December

Cheapest in

June

Average price

$722
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($96 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 8/24

7:15 am-6:37 pm

1 stop11h 22m

Panama City Tocumen Intl

Wed 8/26

3:30 pm-7:42 pm

1 stop28h 12m

$535

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 4/29

6:09 pm-12:46 pm

2 stops18h 37m

Panama City Tocumen Intl

Wed 5/6

1:49 pm-10:33 am

2 stops20h 44m

$551
Quickest round-trip

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 4/29

2:05 pm-4:12 pm

1 stop26h 07m

Panama City Tocumen Intl

Wed 5/6

10:00 am-7:53 pm

1 stop9h 53m

$575

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 4/1

2:05 pm-6:37 pm

1 stop28h 32m

Panama City Tocumen Intl

Thu 4/16

7:55 am-4:13 pm

1 stop8h 18m

$615

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 4/24

2:05 pm-6:37 pm

1 stop28h 32m

Panama City Tocumen Intl

Sun 5/10

3:30 pm-7:53 pm

1 stop28h 23m

$623

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 4/24

6:09 pm-12:46 pm

2 stops18h 37m

Panama City Tocumen Intl

Sun 5/10

1:49 pm-10:33 am

2 stops20h 44m

$686

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Sorted by cheapest first

Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $334). Flying from Biloxi to Panama City in January is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 20, 2026.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,450 reviews

Comfort

7.3

Overall

7.4

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,450 reviews
United Airlines
7.4
Good
9,450 reviews

Comfort

7.3

Overall

7.4

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines and American Airlines can get you from Biloxi to Panama City in just under 11h 22m. Your travel time can differ by up to 7h 15m. There are 1600 mi between Biloxi and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $334). Flying from Biloxi to Panama City in January is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Memphis to Panama City flights
Baton Rouge to Panama City flights
Mobile to Panama City flights
Gulfport to Panama City flights
Jackson to Panama City flights

Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$433FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$543FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$521FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.