$187+ Cheap flights from Irvine, CA to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Mar 7 — Mar 141
1 adult, Economy
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Find cheap flights from Irvine to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Irvine to Panama City Tocumen Intl are usually found in August or September, booked 41 days in advance, depart on a Wednesday or Monday and return on a Thursday
Cheap flight deals from Irvine to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Irvine to Panama CityExplore the most affordable flight options available from Irvine to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
Explore the most affordable flight options available from Irvine to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:04 pm
LAX
- PTY
2 stops16h 12m
Multiple Airlines
Thu 3/126:46 am
PTY
- LAX
2 stops16h 41m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:20 pm
LAX
- PTY
1 stop8h 10m
Multiple Airlines
Fri 3/69:45 am
PTY
- LAX
2 stops39h 21m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$513
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Sun 3/155:50 pm
PTY
- LAX
3 stops29h 37m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$517
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Wed 3/1111:25 am
PTY
- LAX
2 stops12h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$523
This Mytrip deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 am
LAX
- PTY
2 stops29h 35m
Multiple Airlines
Tue 3/105:50 pm
PTY
- LAX
3 stops30h 30m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$529
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:20 pm
LAX
- PTY
1 stop8h 10m
Multiple Airlines
Wed 3/411:25 am
PTY
- LAX
2 stops26h 01m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$531
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:55 pm
LAX
- PTY
1 stop8h 35m
Avianca
Sun 6/215:30 am
PTY
- LAX
1 stop10h 05m
Avianca
Deal found 2/3![Avianca logo]()
$533
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Sun 5/107:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$537
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:20 pm
LAX
- PTY
1 stop8h 10m
Avianca
Mon 3/93:50 pm
PTY
- LAX
1 stop9h 10m
Avianca
Deal found 2/2![Avianca logo]()
$538
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:55 am
LAX
- PTY
2 stops14h 00m
Avianca
Thu 3/269:45 am
PTY
- LAX
2 stops14h 30m
Avianca
Deal found 2/3![Avianca logo]()
$539
This Avianca deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:20 am
LAX
- PTY
1 stop8h 10m
Avianca
Fri 3/209:45 am
PTY
- LAX
2 stops14h 30m
Avianca
Deal found 2/5![Avianca logo]()
$540
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Wed 3/411:25 am
PTY
- LAX
2 stops26h 01m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$541
Best flights from Irvine to Panama CityDiscover carefully curated flight deals from Irvine to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
Discover carefully curated flight deals from Irvine to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 5, 2026.
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Tue 5/267:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Sat 5/237:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/5![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Mon 5/116:10 pm
PTY
- LAX
Nonstop7h 09m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:19 am
LAX
- PTY
Nonstop6h 33m
Copa Airlines
Sun 8/27:55 am
PTY
- LAX
Nonstop6h 44m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Sat 5/167:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:02 am
LAX
- PTY
Nonstop6h 22m
Copa Airlines
Sun 5/107:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/4![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/21:51 am
LAX
- PTY
Nonstop6h 33m
Copa Airlines
Wed 9/26:10 pm
PTY
- LAX
Nonstop6h 48m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$537
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:09 am
LAX
- PTY
Nonstop6h 15m
Copa Airlines
Mon 4/277:55 am
PTY
- LAX
Nonstop7h 05m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$545
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:37 am
LAX
- PTY
Nonstop6h 15m
Copa Airlines
Mon 4/206:10 pm
PTY
- LAX
Nonstop7h 09m
Copa Airlines
Deal found 2/2![Copa Airlines logo]()
$545
Last-minute flights from Irvine to Panama CityDiscover last-minute flight deals from Irvine to Panama City. Data last updated February 5, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to Panama City. Data last updated February 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:20 pm
LAX
- PTY
1 stop8h 10m
Multiple Airlines
Fri 3/69:45 am
PTY
- LAX
2 stops39h 21m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$513
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:20 pm
LAX
- PTY
1 stop8h 10m
Multiple Airlines
Wed 3/411:25 am
PTY
- LAX
2 stops26h 01m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$531
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Wed 3/411:25 am
PTY
- LAX
2 stops26h 01m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$541
This Mytrip deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:20 am
LAX
- PTY
2 stops29h 35m
Multiple Airlines
Tue 3/105:50 pm
PTY
- LAX
3 stops30h 30m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$529
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Wed 3/1111:25 am
PTY
- LAX
2 stops12h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$523
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:20 pm
LAX
- PTY
1 stop8h 10m
Avianca
Mon 3/93:50 pm
PTY
- LAX
1 stop9h 10m
Avianca
Deal found 2/2![Avianca logo]()
$538
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:04 pm
LAX
- PTY
2 stops16h 12m
Multiple Airlines
Thu 3/126:46 am
PTY
- LAX
2 stops16h 41m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$512
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:04 pm
LAX
- PTY
2 stops13h 51m
Multiple Airlines
Sun 3/155:50 pm
PTY
- LAX
3 stops29h 37m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$517
This Avianca deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:20 am
LAX
- PTY
1 stop8h 10m
Avianca
Fri 3/209:45 am
PTY
- LAX
2 stops14h 30m
Avianca
Deal found 2/5![Avianca logo]()
$540
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:55 am
LAX
- PTY
2 stops14h 00m
Avianca
Thu 3/269:45 am
PTY
- LAX
2 stops14h 30m
Avianca
Deal found 2/3![Avianca logo]()
$539
One-way flights from Irvine to Panama CitySearch for one-way flight options from Irvine to Panama City. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
Search for one-way flight options from Irvine to Panama City. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:01 pm
LAX
- PTY
2 stops31h 49m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:30 pm
LAX
- PTY
2 stops35h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:15 am
LAX
- PTY
3 stops28h 45m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:16 pm
LAX
- PTY
3 stops32h 34m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1411:59 pm
LAX
- PTY
2 stops29h 51m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:28 pm
LAX
- PTY
3 stops32h 22m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:28 pm
LAX
- PTY
3 stops59h 02m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:30 pm
LAX
- PTY
2 stops23h 30m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:51 pm
LAX
- PTY
2 stops23h 14m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$225
Find flight deals from Irvine to Panama City
Keep the following information in mind while searching for Irvine to Panama City flight deals. Data was last updated February 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $512 (Mytrip) |
One-way from | $187 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $638 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Irvine to Panama City that are best for you.
Fly from
Irvine
Fly to
Panama City
Route
Depart
Return
Price
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Thu 5/21
2:02 am-10:24 am
Nonstop6h 22m
Panama City Tocumen Intl
Tue 5/26
7:55 am-1:00 pm
Nonstop7h 05m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Thu 5/14
2:02 am-10:24 am
Nonstop6h 22m
Panama City Tocumen Intl
Sat 5/23
7:55 am-1:00 pm
Nonstop7h 05m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Mon 5/4
2:02 am-10:24 am
Nonstop6h 22m
Panama City Tocumen Intl
Mon 5/11
6:10 pm-11:19 pm
Nonstop7h 09m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Tue 7/28
2:19 am-10:52 am
Nonstop6h 33m
Panama City Tocumen Intl
Sun 8/2
7:55 am-12:39 pm
Nonstop6h 44m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Thu 5/7
2:02 am-10:24 am
Nonstop6h 22m
Panama City Tocumen Intl
Sat 5/16
7:55 am-1:00 pm
Nonstop7h 05m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Mon 5/4
2:02 am-10:24 am
Nonstop6h 22m
Panama City Tocumen Intl
Sun 5/10
7:55 am-1:00 pm
Nonstop7h 05m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Sun 8/2
1:51 am-10:24 am
Nonstop6h 33m
Panama City Tocumen Intl
Wed 9/2
6:10 pm-10:58 pm
Nonstop6h 48m
$537
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Thu 4/16
2:09 am-10:24 am
Nonstop6h 15m
Panama City Tocumen Intl
Mon 4/27
7:55 am-1:00 pm
Nonstop7h 05m
$545
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Sun 4/12
2:37 am-10:52 am
Nonstop6h 15m
Panama City Tocumen Intl
Mon 4/20
6:10 pm-11:19 pm
Nonstop7h 09m
$545
Los AngelesPanama City
LAX - PTY
LAXPTY
Los Angeles
Tue 3/10
6:15 am-2:00 pm
3 stops29h 45m
$194
Showing 1-10 of 20 results
Best time to book a flight from Irvine to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Irvine with our price prediction graph.
LAX-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Panama City
IR9-PTY
LAX-PTY
How far ahead should I book a flight from Irvine to Panama City?
Use this chart to determine the optimal time to book a round-trip flight from Irvine to Panama City. Price data was last updated on January 30, 2026.
Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Irvine to Panama City?
Currently, July is the cheapest month in which you can book a flight from Irvine to Panama City (average of $297). Flying from Irvine to Panama City in December is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IR9 to PTY?
Find hourly flight availability from Irvine to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 5, 2026.
When flying from Irvine to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Irvine to Panama City
Explore weekly flight availability from Irvine to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 5, 2026.
The most flights from IR9 to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (8 on average).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 5, 2026.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and American Airlines from Irvine to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Food
6.8
Overall
7.5
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Irvine to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Irvine and Panama City flights
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Top 4 airlines flying from Irvine to Panama City
Discover the top 4 airlines that operate flights from Irvine to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$542 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$243 | Average$535 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$612 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$472 | Average$657 | FlexibilityNo cancel fee | On-time70% |