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Panama City

$204+ Cheap flights from Irvine, CA to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Panama City Tocumen Intl are usually found in August or September, booked 32 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Irvine to Panama City

Cheapest flights from Irvine to Panama City
Explore the most affordable flight options available from Irvine to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:55 pmLAX - PTY
2 stops14h 00mAvianca
Wed 12/313:50 pmPTY - LAX
1 stop9h 10mAvianca
Deal found 12/17$690
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:59 pmLAX - PTY
1 stop13h 55mAmerican Airlines
Tue 5/191:55 pmPTY - LAX
1 stop12h 32mAmerican Airlines
Deal found 12/17$713
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:50 amLAX - PTY
1 stop10h 48mUnited Airlines
Sun 1/184:41 pmPTY - LAX
1 stop9h 52mUnited Airlines
Deal found 12/15$746
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmLAX - PTY
1 stop8h 10mAvianca
Mon 1/57:50 pmPTY - LAX
1 stop18h 45mAvianca
Deal found 12/17$747
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:50 amLAX - PTY
1 stop8h 17mUnited Airlines
Thu 1/84:41 pmPTY - LAX
1 stop9h 52mUnited Airlines
Deal found 12/17$769
This Aeromexico deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:55 amLAX - PTY
2 stops24h 45mAeromexico
Wed 12/312:55 pmPTY - LAX
1 stop10h 35mAeromexico
Deal found 12/17$771
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:55 amLAX - PTY
1 stop8h 43mUnited Airlines
Thu 1/84:41 pmPTY - LAX
1 stop9h 52mUnited Airlines
Deal found 12/17$773
This Aeromexico deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:00 pmLAX - PTY
1 stop11h 40mAeromexico
Fri 1/93:00 pmPTY - LAX
1 stop28h 00mAeromexico
Deal found 12/17$778

Find flight deals from Irvine to Panama City

Keep the following information in mind while searching for Irvine to Panama City flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$506
(Cheapflightsfares)

One-way from

$204
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$751
Provider with most accurate pricing for Los Angeles-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Panama City Tocumen Intl flights.
Search Deals
From Irvine to Panama City Tocumen Intl
Search Deals
One-way flight from Irvine to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Irvine to Panama City that are best for you.

Fly from

Irvine

Fly to

Panama City

Route

Depart

Return

Price

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 2/5

11:55 pm-4:55 pm

2 stops14h 00m

Panama City Tocumen Intl

Wed 2/11

3:50 pm-10:00 pm

1 stop9h 10m

$532

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sun 2/1

12:25 pm-8:50 am

3 stops17h 25m

Panama City Tocumen Intl

Wed 2/4

2:55 pm-12:30 pm

3 stops24h 35m

$546

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 2/3

1:50 pm-2:00 pm

3 stops21h 10m

Panama City Tocumen Intl

Sun 2/8

5:50 pm-9:15 pm

2 stops30h 25m

$546

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Wed 3/18

5:27 pm-10:30 am

2 stops15h 03m

Panama City Tocumen Intl

Sat 3/21

7:50 pm-11:55 am

2 stops18h 05m

$587

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 4/2

12:24 pm-8:39 pm

Nonstop6h 15m

Panama City Tocumen Intl

Mon 4/6

6:10 pm-11:19 pm

Nonstop7h 09m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 3/19

2:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Sun 3/29

6:27 pm-11:42 pm

Nonstop7h 15m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 5/14

12:17 pm-8:39 pm

Nonstop6h 22m

Panama City Tocumen Intl

Fri 5/22

6:10 pm-11:19 pm

Nonstop7h 09m

$598

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 2/5

1:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Mon 2/23

6:14 pm-10:29 pm

Nonstop7h 15m

$608

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sat 2/7

1:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Fri 2/20

6:14 pm-10:29 pm

Nonstop7h 15m

$608

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 2/3

1:01 am-10:21 am

Nonstop6h 20m

Panama City Tocumen Intl

Wed 2/11

7:55 am-12:05 pm

Nonstop7h 10m

$608

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Irvine to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Panama City

How far ahead should I book a flight from Irvine to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Panama City. Price data was last updated on December 12, 2025.

Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Irvine to Panama City?

Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $297). Flying from Irvine to Panama City in December is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to PTY?

Find hourly flight availability from Irvine to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Irvine to Panama City in the morning. Doing so could potentially save you 16% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Irvine to Panama City

Explore weekly flight availability from Irvine to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 18, 2025.

The most flights from IR9 to PTY are scheduled on a Tuesday (10 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Irvine to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,556 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,093 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,490 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Irvine?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Irvine to Panama City. 5 airlines have flights to Tocumen Intl from Irvine on a regular basis. Booking flights from Irvine to Panama City Tocumen Intl should not be difficult; the airport handles an average of 9 inbound flights from Irvine per day.

  • How popular is this Irvine to Panama City flight route?

    Within the past month, 135 users have taken a look at flights from Irvine to Panama City Tocumen Intl.

  • How long is the flight from Irvine to Panama City?

    For as low as $598, Avianca can have you in Panama City from Irvine in 6h 15m. Airlines will cover a distance of 3009 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Irvine to Panama City one-way?

    One-way options have recently been found by users for as low as $179 on Avianca. Other airlines that offer cheap prices include United Airlines from $194 and Copa Airlines from $222 one-way.

  • What are the most reliable airlines from Irvine to Panama City?

    No one likes to see their flight delayed. When booking a flight from Irvine to Panama City consider choosing Copa Airlines (93%), EVA Air (89%) or Asiana Airlines (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Irvine to Panama City?

    While on average a flight from Irvine to Panama City is generally $1,253, our data shows the cheapest flight currently is $199. When looking at the most popular route, (Los Angeles - Panama City Tocumen Intl), you can expect to pay $481 for that flight.

  • Can I find deals for flights from Irvine to Panama City that include hotel bookings?

    Yes. In addition to deals on Irvine to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Panama City.

  • Can I find deals for business class flights from Irvine to Panama City?

    Yes. Cheapflights offers flight deals from Irvine to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $297). Flying from Irvine to Panama City in December is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Irvine to Panama City

Discover the top 5 airlines that operate flights from Irvine to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$203Average$542FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$646FlexibilityNo cancel feeOn-time69%
AviancaCheapest$322Average$568FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$504Average$652FlexibilityNo cancel feeOn-time70%
DeltaCheapest$519Average$716FlexibilityNo cancel feeOn-timeN/A

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