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Panama City

$156+ Cheap flights from Irvine, CA to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Panama City Tocumen Intl are usually found in August or September, booked 41 days in advance, depart on a Wednesday or Monday and return on a Thursday

Cheap flight deals from Irvine to Panama City

Cheapest flights from Irvine to Panama City
Explore the most affordable flight options available from Irvine to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Gotogate deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:50 pm
LAX
-
PTY
1 stop10h 05m
Avianca
Wed 4/153:50 pm
PTY
-
LAX
1 stop8h 50m
Avianca
Deal found 1/28$461
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:20 am
LAX
-
PTY
3 stops30h 35m
Multiple Airlines
Thu 3/192:55 am
PTY
-
LAX
2 stops21h 20m
Multiple Airlines
Deal found 1/27$462
This Gotogate deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/91:00 pm
LAX
-
PTY
2 stops16h 50m
Avianca
Wed 2/112:55 am
PTY
-
LAX
2 stops21h 20m
Avianca
Deal found 1/29$464
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:55 am
LAX
-
PTY
2 stops14h 00m
Avianca
Tue 3/247:50 pm
PTY
-
LAX
1 stop18h 45m
Avianca
Deal found 1/27$465
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:55 am
LAX
-
PTY
2 stops14h 00m
Avianca
Fri 3/203:50 pm
PTY
-
LAX
1 stop9h 10m
Avianca
Deal found 1/27$466
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:55 am
LAX
-
PTY
2 stops14h 00m
Avianca
Wed 3/259:45 am
PTY
-
LAX
2 stops15h 15m
Avianca
Deal found 1/27$467
This Gotogate deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/142:00 pm
LAX
-
PTY
2 stops22h 00m
Avianca
Mon 3/163:50 pm
PTY
-
LAX
1 stop9h 10m
Avianca
Deal found 1/28$468
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:20 pm
LAX
-
PTY
1 stop8h 10m
Avianca
Wed 3/113:50 pm
PTY
-
LAX
1 stop9h 10m
Avianca
Deal found 1/28$471
This Gotogate deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:50 pm
LAX
-
PTY
3 stops16h 00m
Avianca
Sun 3/225:50 pm
PTY
-
LAX
2 stops30h 25m
Avianca
Deal found 1/29$472

Find flight deals from Irvine to Panama City

Keep the following information in mind while searching for Irvine to Panama City flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$461
(Gotogate)

One-way from

$156
(Super.com)

Popular in

December

Cheapest in

August

Average price

$675
Provider with most accurate pricing for Los Angeles-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Panama City Tocumen Intl flights.
Search Deals
From Irvine to Panama City Tocumen Intl
Search Deals
One-way flight from Irvine to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Irvine to Panama City that are best for you.

Fly from

Irvine

Fly to

Panama City

Route

Depart

Return

Price

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Mon 4/6

12:15 am-10:30 am

1 stop8h 15m

Panama City Tocumen Intl

Wed 4/15

5:55 pm-12:25 pm

2 stops20h 30m

$466

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Wed 3/18

12:55 am-4:55 pm

2 stops14h 00m

Panama City Tocumen Intl

Wed 3/25

3:50 pm-11:00 pm

1 stop9h 10m

$467

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Mon 2/16

11:55 pm-4:55 pm

2 stops14h 00m

Panama City Tocumen Intl

Sun 2/22

5:50 pm-12:30 pm

2 stops21h 40m

$491

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Fri 2/20

12:25 pm-8:50 am

3 stops17h 25m

Panama City Tocumen Intl

Mon 2/23

2:55 pm-12:30 pm

3 stops24h 35m

$496

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sun 2/15

11:20 pm-10:30 am

1 stop8h 10m

Panama City Tocumen Intl

Wed 2/18

7:50 pm-11:35 am

1 stop18h 45m

$502

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Mon 6/15

3:05 pm-1:55 am

1 stop8h 50m

Panama City Tocumen Intl

Wed 6/24

10:10 am-10:10 pm

2 stops14h 00m

$522

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Mon 5/4

2:02 am-10:24 am

Nonstop6h 22m

Panama City Tocumen Intl

Mon 5/11

6:10 pm-11:19 pm

Nonstop7h 09m

$537

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sun 4/12

2:37 am-10:52 am

Nonstop6h 15m

Panama City Tocumen Intl

Mon 4/20

6:10 pm-11:19 pm

Nonstop7h 09m

$545

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Mon 4/6

2:09 am-10:24 am

Nonstop6h 15m

Panama City Tocumen Intl

Wed 4/15

6:10 pm-11:19 pm

Nonstop7h 09m

$545

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 4/21

12:24 pm-8:39 pm

Nonstop6h 15m

Panama City Tocumen Intl

Sun 4/26

6:27 pm-11:36 pm

Nonstop7h 09m

$545

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 19 results
1
2

Best time to book a flight from Irvine to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Panama City

How far ahead should I book a flight from Irvine to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Panama City. Price data was last updated on January 23, 2026.

Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Irvine to Panama City?

Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $300). Flying from Irvine to Panama City in December is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to PTY?

Find hourly flight availability from Irvine to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

When flying from Irvine to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Irvine to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,560 reviews
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,492 reviews
Delta
7.9
Good
8,127 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Irvine?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Irvine to Panama City. 5 airlines have flights to Tocumen Intl from Irvine on a regular basis. Booking flights from Irvine to Panama City Tocumen Intl should not be difficult; the airport handles an average of 5 inbound flights from Irvine per day.

  • How popular is this Irvine to Panama City flight route?

    Within the past month, 127 users have taken a look at flights from Irvine to Panama City Tocumen Intl.

  • How long is the flight from Irvine to Panama City?

    For as low as $466, Avianca can have you in Panama City from Irvine in 8h 15m. Airlines will cover a distance of 3009 mi.

  • What are the cheapest airlines to fly from Irvine to Panama City one-way?

    One-way options have recently been found by users for as low as $179 on Avianca. Other airlines that offer cheap prices include United Airlines from $194 and Copa Airlines from $222 one-way.

  • What are the most reliable airlines from Irvine to Panama City?

    No one likes to see their flight delayed. When booking a flight from Irvine to Panama City consider choosing Copa Airlines (82%), EVA Air (80%) or Asiana Airlines (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Irvine to Panama City?

    While on average a flight from Irvine to Panama City is generally $1,277, our data shows the cheapest flight currently is $195. When looking at the most popular route, (Los Angeles - Panama City Tocumen Intl), you can expect to pay $421 for that flight.

  • Can I find deals for flights from Irvine to Panama City that include hotel bookings?

    Yes. In addition to deals on Irvine to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Panama City.

  • Can I find deals for business class flights from Irvine to Panama City?

    Yes. Cheapflights offers flight deals from Irvine to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Irvine to Panama City (average of $300). Flying from Irvine to Panama City in December is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Irvine to Panama City

Discover the top 5 airlines that operate flights from Irvine to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$203Average$542FlexibilityNo cancel feeOn-time71%
AviancaCheapest$264Average$537FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$611FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$474Average$656FlexibilityNo cancel feeOn-time70%
DeltaCheapest$519Average$715FlexibilityNo cancel feeOn-timeN/A

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