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Panama City

$225+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:57 pmGPT - PTY
1 stop26h 10mUnited Airlines
Fri 12/198:55 amPTY - GPT
1 stop13h 42mUnited Airlines
Deal found 11/12$523
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:13 pmGPT - PTY
2 stops18h 34mAmerican Airlines
Fri 12/194:55 pmPTY - GPT
2 stops25h 33mAmerican Airlines
Deal found 11/12$550
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:15 pmGPT - PTY
1 stop20h 30mUnited Airlines
Sat 11/228:55 amPTY - GPT
1 stop13h 41mUnited Airlines
Deal found 11/11$644
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/164:54 pmGPT - PTY
2 stops19h 55mAmerican Airlines
Sat 11/222:43 pmPTY - GPT
2 stops21h 56mAmerican Airlines
Deal found 11/11$660
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:36 pmGPT - PTY
2 stops19h 18mAmerican Airlines
Sat 1/34:55 pmPTY - GPT
2 stops25h 33mAmerican Airlines
Deal found 11/12$1,038
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:55 pmGPT - PTY
1 stop20h 13mMultiple Airlines
Sat 11/2211:25 amPTY - GPT
2 stops32h 50mMultiple Airlines
Deal found 11/11$1,139
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:15 pmGPT - PTY
1 stop22h 52mUnited Airlines
Sat 1/38:55 amPTY - GPT
1 stop13h 42mUnited Airlines
Deal found 11/12$1,502
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:51 pmGPT - PTY
1 stop12h 31mMultiple Airlines
Fri 12/1911:15 pmPTY - GPT
2 stops45h 00mMultiple Airlines
Deal found 11/12$1,953

Cheap flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$443
(United Airlines)

One-way from

$225
(United Airlines)

Popular in

December

Cheapest in

April

Average price

$775
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama City Tocumen Intl
Search Deals
One-way flight from Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Biloxi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 1/18

5:13 pm-5:07 pm

1 stop22h 54m

Panama City Tocumen Intl

Wed 1/28

8:55 am-7:48 pm

1 stop11h 53m

$443

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 1/20

6:33 pm-1:27 pm

2 stops17h 54m

Panama City Tocumen Intl

Sat 1/31

5:00 pm-12:31 pm

2 stops20h 31m

$460

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 1/18

6:33 pm-3:38 pm

2 stops20h 05m

Panama City Tocumen Intl

Wed 1/28

2:27 pm-12:31 pm

2 stops23h 04m

$460

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 1/20

4:42 pm-5:07 pm

1 stop23h 25m

Panama City Tocumen Intl

Sat 1/31

8:55 am-7:48 pm

1 stop11h 53m

$463

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 1/16

5:29 pm-3:52 pm

2 stops21h 23m

Panama City Tocumen Intl

Mon 1/26

4:50 pm-12:31 pm

2 stops20h 41m

$480

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 12/12

1:57 pm-5:07 pm

1 stop26h 10m

Panama City Tocumen Intl

Fri 12/19

8:55 am-9:37 pm

1 stop13h 42m

$523

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 1/17

5:13 pm-2:45 pm

1 stop20h 32m

Panama City Tocumen Intl

Tue 1/27

8:55 am-7:48 pm

1 stop11h 53m

$534

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 1/16

1:57 pm-7:38 pm

1 stop28h 41m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-7:48 pm

1 stop28h 07m

$541

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 12/12

6:13 pm-1:47 pm

2 stops18h 34m

Panama City Tocumen Intl

Fri 12/19

4:55 pm-5:28 pm

2 stops25h 33m

$550

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 1/17

6:33 pm-3:38 pm

2 stops20h 05m

Panama City Tocumen Intl

Tue 1/27

2:27 pm-6:03 pm

2 stops28h 36m

$570

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 18 results
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Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to PTY?

Find hourly flight availability from Biloxi to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

One of the essential ways to save on airfare from Biloxi to Panama City is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 23% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,017 reviews

Entertainment

7.1

Crew

8.1

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,017 reviews
United Airlines
7.4
Good
9,017 reviews

Entertainment

7.1

Crew

8.1

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines and American Airlines can get you from Biloxi to Panama City in just under 17h 54m. Your travel time can differ by up to 5h. There are 1600 mi between Biloxi and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$489FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$535FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$526FlexibilityNo cancel feeOn-timeN/A

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