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Panama City

$386+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:10 am
GPT
-
PTY
1 stop9h 02m
United Airlines
Thu 4/307:55 am
PTY
-
GPT
1 stop29h 26m
United Airlines
Deal found 2/13$474
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:29 pm
GPT
-
PTY
2 stops21h 51m
American Airlines
Tue 3/311:40 pm
PTY
-
GPT
2 stops20h 33m
American Airlines
Deal found 2/11$511
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:55 pm
GPT
-
PTY
1 stop23h 12m
United Airlines
Tue 3/313:30 pm
PTY
-
GPT
1 stop21h 51m
United Airlines
Deal found 2/11$522
This KAYAK deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/162:00 pm
GPT
-
PTY
1 stop28h 38m
Copa Airlines
Tue 3/313:30 pm
PTY
-
GPT
1 stop24h 43m
Copa Airlines
Deal found 2/12$534
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:55 pm
GPT
-
PTY
1 stop20h 50m
United Airlines
Tue 3/177:55 am
PTY
-
GPT
1 stop8h 11m
United Airlines
Deal found 2/11$535
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/84:55 pm
GPT
-
PTY
1 stop23h 12m
United Airlines
Wed 4/13:30 pm
PTY
-
GPT
1 stop24h 43m
United Airlines
Deal found 2/12$542
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:36 pm
GPT
-
PTY
2 stops18h 44m
American Airlines
Wed 4/11:40 pm
PTY
-
GPT
2 stops20h 33m
American Airlines
Deal found 2/12$551
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:10 pm
GPT
-
PTY
2 stops18h 36m
American Airlines
Thu 4/301:49 pm
PTY
-
GPT
2 stops20h 51m
American Airlines
Deal found 2/13$561
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:55 pm
GPT
-
PTY
1 stop25h 43m
United Airlines
Fri 2/278:55 am
PTY
-
GPT
1 stop8h 06m
United Airlines
Deal found 2/10$605
This KAYAK deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:29 pm
GPT
-
PTY
2 stops20h 51m
GOL
Wed 4/13:51 pm
PTY
-
GPT
2 stops18h 22m
GOL
Deal found 2/12$673
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:55 pm
GPT
-
PTY
1 stop24h 43m
United Airlines
Wed 4/13:30 pm
PTY
-
GPT
1 stop21h 51m
United Airlines
Deal found 2/12$674

Find flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated February 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$474
(United Airlines)

One-way from

$386
(United Airlines)

Popular in

December

Cheapest in

June

Average price

$524
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama City Tocumen Intl
Search Deals
One-way flight from Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($96 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Biloxi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 4/15

7:10 am-4:12 pm

1 stop9h 02m

Panama City Tocumen Intl

Thu 4/30

7:55 am-1:21 pm

1 stop29h 26m

$474

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 3/16

4:29 pm-2:20 pm

2 stops21h 51m

Panama City Tocumen Intl

Tue 3/31

1:40 pm-10:13 am

2 stops20h 33m

$511

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 3/16

4:55 pm-4:07 pm

1 stop23h 12m

Panama City Tocumen Intl

Tue 3/31

3:30 pm-1:21 pm

1 stop21h 51m

$522

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 3/16

2:00 pm-6:38 pm

1 stop28h 38m

Panama City Tocumen Intl

Tue 3/31

3:30 pm-4:13 pm

1 stop24h 43m

$534

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 3/3

4:55 pm-2:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Tue 3/17

7:55 am-4:06 pm

1 stop8h 11m

$535

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Fri 3/27

4:55 pm-6:38 pm

1 stop25h 43m

Panama City Tocumen Intl

Fri 4/3

3:30 pm-7:53 pm

1 stop28h 23m

$542

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 3/8

4:55 pm-4:07 pm

1 stop23h 12m

Panama City Tocumen Intl

Wed 4/1

3:30 pm-4:13 pm

1 stop24h 43m

$542

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 3/8

7:36 pm-2:20 pm

2 stops18h 44m

Panama City Tocumen Intl

Wed 4/1

1:40 pm-10:13 am

2 stops20h 33m

$551

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 4/15

6:10 pm-12:46 pm

2 stops18h 36m

Panama City Tocumen Intl

Thu 4/30

1:49 pm-10:40 am

2 stops20h 51m

$561

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 3/7

4:55 pm-6:38 pm

1 stop24h 43m

Panama City Tocumen Intl

Wed 4/1

3:30 pm-1:21 pm

1 stop21h 51m

$674

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 13 results
1
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Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $334). Flying from Biloxi to Panama City in January is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 14, 2026.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,289 reviews

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,289 reviews
United Airlines
7.4
Good
9,289 reviews

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines, American Airlines, and Copa Airlines can get you from Biloxi to Panama City in just under 9h 02m. Your travel time can differ by up to 19h 36m. There are 1600 mi between Biloxi and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $334). Flying from Biloxi to Panama City in January is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$435FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$528FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$521FlexibilityNo cancel feeOn-timeN/A

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