HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$436+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Biloxi to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:11 pmGPT - PTY
1 stop22h 56mUnited Airlines
Mon 12/228:55 amPTY - GPT
1 stop13h 42mUnited Airlines
Deal found 12/2$554
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:00 amGPT - PTY
1 stop9h 07mUnited Airlines
Tue 12/168:55 amPTY - GPT
1 stop13h 27mUnited Airlines
Deal found 12/2$586
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:32 pmGPT - PTY
2 stops21h 10mAmerican Airlines
Tue 12/164:43 pmPTY - GPT
2 stops21h 30mAmerican Airlines
Deal found 12/2$590
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:38 pmGPT - PTY
2 stops22h 04mAmerican Airlines
Mon 12/224:55 pmPTY - GPT
2 stops24h 13mAmerican Airlines
Deal found 12/2$640
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:55 pmGPT - PTY
2 stops23h 35mMultiple Airlines
Mon 12/229:40 amPTY - GPT
1 stop24h 45mMultiple Airlines
Deal found 12/2$1,341

Find flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$436
(United Airlines)

Popular in

December

Cheapest in

April

Average price

$983
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Biloxi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 1/26

7:00 am-5:07 pm

1 stop9h 07m

Panama City Tocumen Intl

Thu 1/29

8:55 am-3:58 pm

1 stop8h 03m

$436

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 12/14

5:11 pm-5:07 pm

1 stop22h 56m

Panama City Tocumen Intl

Mon 12/22

8:55 am-9:37 pm

1 stop13h 42m

$554

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 3/16

4:28 pm-2:22 pm

2 stops21h 54m

Panama City Tocumen Intl

Sun 3/22

1:44 pm-12:34 pm

2 stops22h 50m

$575

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 3/16

4:55 pm-1:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Sun 3/22

7:55 am-7:45 pm

1 stop11h 50m

$613

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 3/14

4:28 pm-2:22 pm

2 stops21h 54m

Panama City Tocumen Intl

Sat 3/28

1:44 pm-10:13 am

2 stops20h 29m

$625

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 12/14

4:38 pm-3:42 pm

2 stops22h 04m

Panama City Tocumen Intl

Mon 12/22

4:55 pm-4:08 pm

2 stops24h 13m

$640

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 3/14

4:55 pm-6:38 pm

1 stop25h 43m

Panama City Tocumen Intl

Sat 3/28

7:55 am-4:06 pm

1 stop8h 11m

$757

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sun 12/14

7:55 pm-8:30 pm

2 stops23h 35m

Panama City Tocumen Intl

Mon 12/22

9:40 am-9:25 am

1 stop24h 45m

$1,341

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to PTY?

Find hourly flight availability from Biloxi to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

One of the essential ways to save on airfare from Biloxi to Panama City is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 23% on airfare.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,066 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,066 reviews
United Airlines
7.4
Good
9,066 reviews

Boarding

7.7

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines and American Airlines can get you from Biloxi to Panama City in just under 9h 07m. Your travel time can differ by up to 12h 47m. There are 1600 mi between Biloxi and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Memphis to Panama City flights
Jackson to Panama City flights
Baton Rouge to Panama City flights
Mobile to Panama City flights
Gulfport to Panama City flights

Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$443FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$535FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$527FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.