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Panama City

$481+ Cheap flights from Biloxi, MS to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Biloxi to Panama City

Keep the following information in mind while searching for Biloxi to Panama City flight deals. Data was last updated January 12, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$481
(American Airlines)

Popular in

December

Cheapest in

June
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
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From Biloxi to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($187 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($33 potential savings vs. average RT price).
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Find flight deals from Biloxi to Panama City

Cheapest flights from Biloxi to Panama City
Explore the most affordable flight options available from Biloxi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:29 pm
GPT
-
PTY
2 stops21h 46m
American Airlines
Thu 3/54:05 pm
PTY
-
GPT
2 stops19h 08m
American Airlines
Deal found 1/12$481
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:55 pm
GPT
-
PTY
1 stop25h 43m
United Airlines
Fri 2/274:41 pm
PTY
-
GPT
1 stop21h 39m
United Airlines
Deal found 1/11$512
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:05 am
GPT
-
PTY
1 stop9h 02m
United Airlines
Thu 3/58:55 am
PTY
-
GPT
1 stop8h 11m
United Airlines
Deal found 1/12$513
This United Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:55 pm
GPT
-
PTY
1 stop25h 43m
United Airlines
Tue 3/34:41 pm
PTY
-
GPT
1 stop27h 53m
United Airlines
Deal found 1/10$527
This American Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:31 am
GPT
-
PTY
2 stops30h 09m
American Airlines
Tue 3/32:40 pm
PTY
-
GPT
2 stops20h 33m
American Airlines
Deal found 1/10$551
This United Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:55 pm
GPT
-
PTY
1 stop20h 50m
United Airlines
Sat 3/287:55 am
PTY
-
GPT
1 stop11h 50m
United Airlines
Deal found 1/10$555
This KAYAK deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/191:57 pm
GPT
-
PTY
1 stop23h 48m
Copa Airlines
Sat 2/74:41 pm
PTY
-
GPT
1 stop24h 17m
Copa Airlines
Deal found 1/12$582
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/191:57 pm
GPT
-
PTY
1 stop28h 41m
United Airlines
Sat 2/74:41 pm
PTY
-
GPT
1 stop28h 07m
United Airlines
Deal found 1/12$583
This American Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:29 pm
GPT
-
PTY
2 stops20h 11m
American Airlines
Sat 3/283:10 pm
PTY
-
GPT
2 stops21h 24m
American Airlines
Deal found 1/10$626
This KAYAK deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/145:13 pm
GPT
-
PTY
1 stop20h 32m
Copa Airlines
Wed 1/2111:35 am
PTY
-
GPT
1 stop9h 13m
Copa Airlines
Deal found 1/11$732
This American Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:54 pm
GPT
-
PTY
2 stops19h 42m
American Airlines
Sat 11/282:43 pm
PTY
-
GPT
2 stops21h 56m
American Airlines
Deal found 1/10$741
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:20 pm
GPT
-
PTY
2 stops42h 35m
Multiple Airlines
Thu 3/56:17 pm
PTY
-
GPT
1 stop15h 43m
Multiple Airlines
Deal found 1/12$895

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Biloxi to Panama City that are best for you.

Fly from

Biloxi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Mon 2/23

4:55 pm-2:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Fri 2/27

4:41 pm-1:20 pm

1 stop21h 39m

$512

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 2/26

7:05 am-5:07 pm

1 stop9h 02m

Panama City Tocumen Intl

Thu 3/5

8:55 am-4:06 pm

1 stop8h 11m

$513

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 2/24

4:55 pm-7:38 pm

1 stop25h 43m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-7:34 pm

1 stop27h 53m

$527

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Tue 2/24

6:31 am-1:40 pm

2 stops30h 09m

Panama City Tocumen Intl

Tue 3/3

2:40 pm-10:13 am

2 stops20h 33m

$551

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 3/14

4:55 pm-1:45 pm

1 stop20h 50m

Panama City Tocumen Intl

Sat 3/28

7:55 am-7:45 pm

1 stop11h 50m

$555

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Sat 3/14

4:29 pm-12:40 pm

2 stops20h 11m

Panama City Tocumen Intl

Sat 3/28

3:10 pm-12:34 pm

2 stops21h 24m

$626

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Thu 2/26

7:20 pm-2:55 pm

2 stops42h 35m

Panama City Tocumen Intl

Thu 3/5

6:17 pm-9:00 am

1 stop15h 43m

$895

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/9

Best time to book a flight from Biloxi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama City

What is the cheapest month to book a flight from Biloxi to Panama City?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 12, 2026.
Read through reviews of airlines operating flights from Biloxi to Panama City, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,143 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,143 reviews
United Airlines
7.4
Good
9,143 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Biloxi?

    If you book a flight to Panama City from Biloxi, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Biloxi to Tocumen Intl per day from 3 different airlines.

  • How long is the flight from Biloxi to Panama City?

    United Airlines can get you from Biloxi to Panama City in just under 20h 50m. Your travel time can differ by up to . There are 1600 mi between Biloxi and Panama City.

  • Can I find deals for flights from Biloxi to Panama City that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama City.

  • Can I find deals for business class flights from Biloxi to Panama City?

    Yes. Cheapflights offers flight deals from Biloxi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama City (average of $346). Flying from Biloxi to Panama City in January is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Biloxi to Panama City

Discover the top 3 airlines that operate flights from Biloxi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$433FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$534FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$521FlexibilityNo cancel feeOn-timeN/A

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