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Palermo

$664+ Cheap flights from Missouri to Palermo (PMO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — PMO
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Missouri to Palermo

Cheapest flights from Missouri to Palermo
Explore the most affordable flight options available from Missouri to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This KLM deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:41 amMCI - PMO
2 stops19h 24mKLM
Fri 1/236:10 amPMO - MCI
2 stops24h 41mKLM
Deal found 12/19$664
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amMCI - PMO
2 stops52h 45mMultiple Airlines
Mon 12/299:30 amPMO - MCI
2 stops19h 20mMultiple Airlines
Deal found 12/21$2,375

Find flight deals from Missouri to Palermo

Keep the following information in mind while searching for Missouri to Palermo flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$722
(United Airlines)

Popular in

November

Cheapest in

March

Average price

$1,111
Provider with most accurate pricing for Lambert-St Louis-Palermo Punta Raisi flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Palermo Punta Raisi flights.
Search Deals
From Missouri to Palermo Punta Raisi
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Missouri to Palermo that are best for you.

Fly from

Missouri

Fly to

Palermo

Route

Depart

Return

Price

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Wed 2/4

5:45 pm-11:40 am

2 stops34h 55m

Palermo Punta Raisi

Sun 2/8

6:10 am-7:56 pm

2 stops20h 46m

$722

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sat 2/28

12:37 pm-1:10 pm

2 stops17h 33m

Palermo Punta Raisi

Sat 3/14

12:15 pm-8:41 pm

2 stops38h 26m

$806

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sat 2/28

12:37 pm-1:10 pm

2 stops17h 33m

Palermo Punta Raisi

Sat 3/14

9:45 am-9:59 pm

2 stops18h 14m

$821

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sun 3/15

6:30 pm-6:20 pm

2 stops41h 50m

Palermo Punta Raisi

Sun 3/22

6:25 pm-7:42 pm

2 stops55h 17m

$973

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sat 2/28

11:27 am-1:10 pm

3 stops18h 43m

Palermo Punta Raisi

Sat 3/14

6:10 am-9:59 pm

3 stops21h 49m

$1,243

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Mon 6/1

7:24 am-11:45 am

2 stops45h 21m

Palermo Punta Raisi

Tue 6/30

12:20 pm-11:47 pm

2 stops42h 27m

$1,261

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Fri 3/13

1:15 pm-11:25 am

2 stops16h 10m

Palermo Punta Raisi

Sun 3/22

6:25 pm-7:42 pm

2 stops55h 17m

$1,286

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Mon 6/1

7:24 am-11:45 am

2 stops45h 21m

Palermo Punta Raisi

Wed 6/17

12:55 pm-8:16 pm

2 stops38h 21m

$1,290

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sat 3/14

5:40 pm-11:40 am

2 stops36h 00m

Palermo Punta Raisi

Sat 3/21

12:15 pm-7:42 pm

2 stops37h 27m

$1,473

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Best time to book a flight from Missouri to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Palermo

What is the cheapest time of day to fly from MO to PMO?

Find hourly flight availability from Missouri to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

It’s optimal to fly from Missouri to Palermo in the evening. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from Missouri?

    Most people fly into Palermo Punta Raisi (PMO) if they book a flight to Palermo from Missouri. Punta Raisi is conveniently located just 15.2 mi from Palermo’s city center.

  • How long is the flight from Missouri to Palermo?

    A quick flight from Missouri to Palermo can take about 17h 33m. United Airlines provides one of the quickest options available for as low as $806. There are 5396 mi between Missouri and Palermo. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to Palermo that include hotel bookings?

    Yes. In addition to deals on Missouri to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Palermo.

  • Can I find deals for business class flights from Missouri to Palermo?

    Yes. Cheapflights offers flight deals from Missouri to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

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Alternative routes for Missouri to Palermo

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Missouri to Palermo

Discover the top airline that operate flights from Missouri to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$806Average$1,255FlexibilityNo cancel feeOn-time76%

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