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Palermo

$565+ Cheap flights from Missouri to Palermo (PMO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PMO
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Missouri to Palermo

Keep the following information in mind while searching for Missouri to Palermo flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$565
(KLM)

Popular in

December

Cheapest in

March

Average price

$1,123
Provider with most accurate pricing for Lambert-St Louis-Palermo Punta Raisi flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Palermo Punta Raisi flights.
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From Missouri to Palermo Punta Raisi
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Highest demand for flights based on searches. 34% potential increase in price ($753 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($155 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Palermo

Cheapest flights from Missouri to Palermo
Explore the most affordable flight options available from Missouri to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/283:25 pmMCI - PMO
2 stops15h 30mKLM
Sun 12/710:00 amPMO - MCI
2 stops20h 47mKLM
Deal found 10/27$565
This United deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:45 pmMCI - PMO
2 stops16h 20mMultiple Airlines
Sat 11/812:15 pmPMO - MCI
2 stops51h 41mMultiple Airlines
Deal found 10/28$957
This United deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:43 pmMCI - PMO
3 stops32h 42mMultiple Airlines
Sun 12/76:25 pmPMO - MCI
2 stops30h 00mMultiple Airlines
Deal found 10/27$983
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:36 pmMCI - PMO
2 stops19h 04mKLM
Sat 11/82:40 pmPMO - MCI
2 stops38h 55mKLM
Deal found 10/27$1,044
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:36 amMCI - PMO
3 stops39h 49mUnited Airlines
Sun 12/76:10 amPMO - MCI
3 stops44h 17mUnited Airlines
Deal found 10/27$1,196
This Air Canada deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:58 amMCI - PMO
3 stops19h 42mAir Canada
Sat 11/812:15 pmPMO - MCI
3 stops29h 25mAir Canada
Deal found 10/28$4,304

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Missouri to Palermo that are best for you.

Fly from

Missouri

Fly to

Palermo

Route

Depart

Return

Price

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Fri 11/28

3:25 pm-1:55 pm

2 stops15h 30m

Palermo Punta Raisi

Sun 12/7

10:00 am-11:47 pm

2 stops20h 47m

$565

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Fri 1/9

11:29 am-11:25 am

2 stops16h 56m

Palermo Punta Raisi

Sat 1/17

12:10 pm-9:59 pm

2 stops16h 49m

$755

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Fri 1/9

8:00 am-11:40 am

3 stops20h 40m

Palermo Punta Raisi

Sat 1/17

6:10 am-9:59 pm

3 stops22h 49m

$960

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Fri 11/28

6:43 pm-10:25 am

3 stops32h 42m

Palermo Punta Raisi

Sun 12/7

6:25 pm-5:25 pm

2 stops30h 00m

$983

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Tue 1/6

6:30 pm-1:55 pm

2 stops36h 25m

Palermo Punta Raisi

Sun 1/11

6:25 pm-9:59 pm

2 stops34h 34m

$996

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Tue 1/6

11:29 am-1:40 pm

3 stops19h 11m

Palermo Punta Raisi

Sun 1/11

10:00 am-10:32 am

3 stops31h 32m

$1,647

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Best time to book a flight from Missouri to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Palermo

What is the cheapest time of day to fly from MO to PMO?

Find hourly flight availability from Missouri to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Missouri to Palermo in the evening. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from Missouri?

    Most people fly into Palermo Punta Raisi (PMO) if they book a flight to Palermo from Missouri. Punta Raisi is conveniently located just 15.2 mi from Palermo’s city center.

  • How long is the flight from Missouri to Palermo?

    A quick flight from Missouri to Palermo can take about 15h 30m. KLM provides one of the quickest options available for as low as $565. There are 5396 mi between Missouri and Palermo. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to Palermo that include hotel bookings?

    Yes. In addition to deals on Missouri to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Palermo.

  • Can I find deals for business class flights from Missouri to Palermo?

    Yes. Cheapflights offers flight deals from Missouri to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

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Top airline flying from Missouri to Palermo

Discover the top airline that operate flights from Missouri to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$806Average$1,255FlexibilityNo cancel feeOn-time76%

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