HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$254+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated julio 3, 2025.

Round-trip from

$507
(Mytrip)

One-way from

$254
(Mytrip)

Popular in

May

Cheapest in

November

Average price

$1,176
From Missouri to Italy
Search Deals
One-way flight from Missouri to Italy
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($286 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/911:45 amSTL - FCO
1 stop13h 00mUnited Airlines
vie. 11/211:15 pmFCO - STL
2 stops32h 05mUnited Airlines
Deal found 7/3$484
This CheapOair deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/229:15 amSTL - FCO
1 stop19h 30mMultiple Airlines
vie. 11/77:05 amFCO - STL
1 stop13h 50mMultiple Airlines
Deal found 7/2$502
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/34:05 pmSTL - MXP
2 stops34h 50mMultiple Airlines
dom. 12/77:00 amMXP - STL
1 stop13h 55mMultiple Airlines
Deal found 7/3$507
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/229:15 amSTL - FCO
2 stops17h 00mAir Canada
vie. 11/71:35 pmFCO - STL
2 stops32h 54mAir Canada
Deal found 7/2$509
This CheapOair deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/34:05 pmSTL - MXP
2 stops34h 50mAir Canada
dom. 12/71:05 pmMXP - STL
2 stops40h 27mAir Canada
Deal found 7/3$509
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/97:20 amSTL - FCO
2 stops16h 45mDelta
vie. 11/219:20 amFCO - STL
2 stops21h 19mDelta
Deal found 7/3$511
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:24 pmSTL - MXP
1 stop12h 06mUnited Airlines
dom. 12/71:05 pmMXP - STL
2 stops32h 15mUnited Airlines
Deal found 7/2$511
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:00 amSTL - MXP
2 stops20h 45mDelta
mar. 11/1811:05 amMXP - STL
1 stop17h 54mDelta
Deal found 7/3$539
This KLM deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/67:20 amSTL - MXP
2 stops19h 25mKLM
mar. 11/1811:05 amMXP - STL
1 stop17h 54mKLM
Deal found 7/2$558
This Ovago deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/611:49 amSTL - MXP
1 stop12h 41mLufthansa
mar. 11/186:40 pmMXP - STL
1 stop26h 15mLufthansa
Deal found 7/1$560
This Norse deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Norse is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/116:00 amMCI - FCO
1 stop22h 10mMultiple Airlines
jue. 8/217:15 amFCO - MCI
1 stop37h 46mMultiple Airlines
Deal found 7/2$574
This Iberia deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/165:52 pmSTL - FCO
1 stop31h 13mIberia
jue. 9/117:35 amFCO - STL
2 stops19h 41mIberia
Deal found 7/2$575

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Missouri

Fly to

Italy

Route

Depart

Return

Price

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mié. 12/3

4:05 pm-9:55 am

2 stops34h 50m

Milan Malpensa

dom. 12/7

7:00 am-1:55 pm

1 stop13h 55m

$507

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mié. 12/3

4:05 pm-9:55 am

2 stops34h 50m

Milan Malpensa

dom. 12/7

1:05 pm-10:32 pm

2 stops40h 27m

$509

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mié. 12/3

12:24 pm-7:30 am

1 stop12h 06m

Milan Malpensa

dom. 12/7

1:05 pm-2:20 pm

2 stops32h 15m

$511

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mar. 8/19

1:30 pm-9:15 am

1 stop12h 45m

Rome Fiumicino

jue. 9/11

11:30 am-12:25 pm

2 stops31h 55m

$539

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

dom. 8/17

1:30 pm-9:15 am

1 stop12h 45m

Rome Fiumicino

jue. 9/11

2:30 pm-2:19 pm

2 stops30h 49m

$546

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mié. 12/3

1:30 pm-9:05 am

1 stop12h 35m

Milan Malpensa

dom. 12/7

12:00 pm-4:40 pm

1 stop35h 40m

$549

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mié. 10/1

1:30 pm-9:15 am

1 stop12h 45m

Rome Fiumicino

mié. 10/15

7:10 am-1:30 pm

1 stop13h 20m

$555

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

jue. 11/6

11:49 am-7:30 am

1 stop12h 41m

Milan Malpensa

mar. 11/18

6:40 pm-1:55 pm

1 stop26h 15m

$560

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

sáb. 8/16

5:11 pm-7:35 am

1 stop31h 24m

Rome Fiumicino

mié. 9/10

11:35 am-7:07 pm

1 stop14h 32m

$566

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

lun. 8/11

6:00 am-11:10 am

1 stop22h 10m

Rome Fiumicino

jue. 8/21

7:15 am-2:01 pm

1 stop37h 46m

$574

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, January is the cheapest month in which you can book a flight from Missouri to Italy (average of $703). Flying from Missouri to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IT?

Find hourly flight availability from Missouri to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Italy as you normally would.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated julio 3, 2025.
Read through reviews of airlines operating flights from Missouri to Italy, such as Delta, KLM, and Austrian Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,367 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Austrian Airlines
7.6
Good
809 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Finnair
7.6
Good
1,306 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,465 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Italy one-way?

    $326 is the cheapest one-way deal found within the past few days, from Air Canada. You may also be able to find cheap deals on United Airlines and Lufthansa, with prices starting from $424 and $508, respectively.

  • Can I find deals for flights from Missouri to Italy that include hotel bookings?

    Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

  • Can I find deals for business class flights from Missouri to Italy?

    Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Italy?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Italy (average of $703). Flying from Missouri to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Heathrow flights
Newark to Heathrow flights
John F Kennedy Intl to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Charles de Gaulle flights
John F Kennedy Intl to Istanbul flights
Newark to Charles de Gaulle flights
Newark to Leonardo da Vinci/Fiumicino flights
Newark to Orly flights
John F Kennedy Intl to Gatwick flights
Newark to Athens flights
John F Kennedy Intl to Lisbon flights
John F Kennedy Intl to Athens flights
Los Angeles to Heathrow flights
Dulles Intl to Heathrow flights
John F Kennedy Intl to London City flights
LaGuardia to Heathrow flights
Boston to Heathrow flights
Newark to Gatwick flights
O'Hare Intl to Heathrow flights
John F Kennedy Intl to Barcelona-El Prat flights
John F Kennedy Intl to Orly flights
Newark to Lisbon flights
John F Kennedy Intl to Madrid flights
Newark to Barcelona-El Prat flights
LaGuardia to Charles de Gaulle flights
San Francisco to Heathrow flights
Miami to Madrid flights
Seattle to Heathrow flights
Dulles Intl to Charles de Gaulle flights
Baltimore to Heathrow flights
O'Hare Intl to Charles de Gaulle flights
Newark to Madrid flights
Newark to Dublin flights
John F Kennedy Intl to Malpensa flights
LaGuardia to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Frederic Chopin flights
Newark to Malpensa flights
Dallas/Fort Worth to Heathrow flights
O'Hare Intl to Leonardo da Vinci/Fiumicino flights
LaGuardia to Gatwick flights
John F Kennedy Intl to Dublin flights
Boston to Charles de Gaulle flights
John F Kennedy Intl to Stansted flights
Dulles Intl to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Amsterdam flights
Dallas/Fort Worth to Charles de Gaulle flights
Boston to Leonardo da Vinci/Fiumicino flights
Newark to Frankfurt flights
LaGuardia to Istanbul flights
Boston to Dublin flights

Top 8 airlines flying from Missouri to Italy

Discover the top 8 airlines that operate flights from Missouri to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$554Average$1,042FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$573Average$1,021FlexibilityNo cancel feeOn-time75%
British AirwaysCheapest$586Average$1,137FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$633Average$1,170FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$675Average$1,303FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$707Average$1,187FlexibilityNo cancel feeOn-time71%
IberiaCheapest$739Average$1,285FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$784Average$1,206FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.