To save up to 32% on this flight, we recommend booking at least 46 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from New York LaGuardia Airport to Palermo from $867 1-2 weeks out and tickets from $954 for flights departing within the next 72 hours.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from New York LaGuardia Airport to Palermo as you normally would.