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$50+ Cheap flights from Mississippi to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — CVG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Mississippi to Ohio

Cheapest flights from Mississippi to Ohio
Explore the most affordable flight options available from Mississippi to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:04 pm
MEM
-
CLE
1 stop23h 50m
Frontier
Sun 3/17:00 am
CLE
-
MEM
1 stop12h 19m
Frontier
Deal found 1/28$133
This Travelocity deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
PIT
1 stop11h 10m
Spirit Airlines
Wed 3/45:45 am
PIT
-
MEM
1 stop5h 35m
Spirit Airlines
Deal found 1/28$138
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:04 pm
MEM
-
DTW
1 stop12h 03m
Frontier
Sat 3/711:54 am
DTW
-
MEM
1 stop27h 48m
Frontier
Deal found 1/28$142
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:04 pm
MEM
-
DTW
1 stop12h 03m
Multiple Airlines
Sun 3/12:35 pm
DTW
-
MEM
1 stop4h 44m
Multiple Airlines
Deal found 1/26$143
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:04 pm
MEM
-
CLE
1 stop27h 07m
Multiple Airlines
Mon 2/236:29 pm
CLE
-
MEM
1 stop16h 51m
Multiple Airlines
Deal found 1/28$175
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:12 pm
MEM
-
DTW
1 stop13h 47m
Frontier
Sun 3/159:02 am
DTW
-
MEM
1 stop10h 18m
Frontier
Deal found 1/27$177
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
DTW
1 stop11h 10m
Spirit Airlines
Wed 3/45:15 am
DTW
-
MEM
1 stop6h 05m
Spirit Airlines
Deal found 1/28$180
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:50 pm
MEM
-
DTW
1 stop14h 30m
Multiple Airlines
Sun 2/85:05 am
DTW
-
MEM
1 stop13h 05m
Multiple Airlines
Deal found 1/27$190
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:04 pm
MEM
-
CLE
1 stop23h 50m
Multiple Airlines
Mon 2/164:02 pm
CLE
-
MEM
1 stop19h 18m
Multiple Airlines
Deal found 1/27$190
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:07 pm
MEM
-
CMH
1 stop16h 37m
Multiple Airlines
Tue 2/248:02 pm
CMH
-
MEM
1 stop15h 18m
Multiple Airlines
Deal found 1/28$193
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:15 am
MEM
-
DTW
1 stop6h 23m
Multiple Airlines
Sun 2/222:35 pm
DTW
-
MEM
1 stop4h 44m
Multiple Airlines
Deal found 1/27$195
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
MEM
-
PIT
1 stop11h 10m
Multiple Airlines
Wed 3/46:00 am
PIT
-
MEM
2 stops35h 12m
Multiple Airlines
Deal found 1/28$197

Find flight deals from Mississippi to Ohio

Keep the following information in mind while searching for Mississippi to Ohio flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$133
(Kiwi.com)

One-way from

$50
(Expedia)

Popular in

March

Cheapest in

October
Provider with most accurate pricing for Jackson-Evers Intl-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Cleveland Hopkins Intl flights.
Search Deals
From Mississippi to Ohio
Search Deals
One-way flight from Mississippi to Ohio
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($35 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Mississippi to Ohio that are best for you.

Fly from

Mississippi

Fly to

Ohio

Route

Depart

Return

Price

MemphisPittsburgh

MEM - PIT

MEMPIT

Memphis

Wed 2/25

11:15 am-11:25 pm

1 stop11h 10m

Pittsburgh

Wed 3/4

5:45 am-10:20 am

1 stop5h 35m

$138

MemphisDetroit

MEM - DTW

MEMDTW

Memphis

Thu 2/26

7:04 pm-8:07 am

1 stop12h 03m

Detroit Metropolitan Wayne County

Sun 3/1

2:35 pm-6:19 pm

1 stop4h 44m

$143

MemphisCleveland

MEM - CLE

MEMCLE

Memphis

Thu 2/26

7:04 pm-5:47 pm

2 stops21h 43m

Cleveland Hopkins Intl

Sun 3/1

7:00 am-6:19 pm

1 stop12h 19m

$161

MemphisDetroit

MEM - DTW

MEMDTW

Memphis

Wed 2/25

11:15 am-11:25 pm

1 stop11h 10m

Detroit Metropolitan Wayne County

Wed 3/4

5:15 am-10:20 am

1 stop6h 05m

$180

MemphisCleveland

MEM - CLE

MEMCLE

Memphis

Thu 2/12

7:04 pm-7:54 pm

1 stop23h 50m

Cleveland Hopkins Intl

Mon 2/16

4:02 pm-10:20 am

1 stop19h 18m

$190

MemphisColumbus

MEM - CMH

MEMCMH

Memphis

Mon 2/23

5:07 pm-10:44 am

1 stop16h 37m

Columbus

Tue 2/24

8:02 pm-10:20 am

1 stop15h 18m

$193

MemphisPittsburgh

MEM - PIT

MEMPIT

Memphis

Wed 2/25

11:15 am-11:25 pm

1 stop11h 10m

Pittsburgh

Wed 3/4

6:00 am-4:12 pm

2 stops35h 12m

$197

MemphisCincinnati

MEM - CVG

MEMCVG

Memphis

Fri 2/20

5:00 pm-11:33 pm

2 stops29h 33m

Cincinnati Cinci./N. Kentucky

Sun 2/22

1:07 pm-6:19 pm

1 stop6h 12m

$203

MemphisCleveland

MEM - CLE

MEMCLE

Memphis

Thu 2/19

7:04 pm-5:47 pm

2 stops21h 43m

Cleveland Hopkins Intl

Mon 2/23

6:29 pm-10:20 am

1 stop16h 51m

$207

MemphisColumbus

MEM - CMH

MEMCMH

Memphis

Tue 3/31

9:50 am-8:29 pm

1 stop9h 39m

Columbus

Mon 4/6

5:59 pm-5:47 pm

1 stop24h 48m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Ohio

What is the cheapest month to book a flight from Mississippi to Ohio?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Ohio (average of $153). Flying from Mississippi to Ohio in December is currently the most expensive (average of $427). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Mississippi to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Ohio?

    For as low as $220, Spirit Airlines can have you in Ohio from Mississippi in 9h 39m. The distance from Mississippi to Ohio is about 517 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Ohio that include hotel bookings?

    Yes. In addition to deals on Mississippi to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Ohio.

  • Can I find deals for business class flights from Mississippi to Ohio?

    Yes. Cheapflights offers flight deals from Mississippi to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Ohio?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Ohio (average of $153). Flying from Mississippi to Ohio in December is currently the most expensive (average of $427). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Ohio

Discover the top 2 airlines that operate flights from Mississippi to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$153Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$466FlexibilityNo cancel feeOn-time71%

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