$90+ Cheap flights from Des Moines (DSM) to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CVG
Apr 13 — Apr 201
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to OhioExplore the most affordable flight options available from Des Moines to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.
Explore the most affordable flight options available from Des Moines to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
DSM
- CLE
1 stop13h 33m
Frontier
Sun 3/228:51 pm
CLE
- DSM
1 stop23h 25m
Frontier
Deal found 3/9![Frontier logo]()
$271
This Gotogate deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:21 pm
DSM
- CMH
1 stop21h 17m
Frontier
Sun 3/297:33 pm
CMH
- DSM
1 stop24h 43m
Frontier
Deal found 3/12![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:40 am
DSM
- DTW
1 stop8h 53m
Multiple Airlines
Mon 4/1311:54 am
DTW
- DSM
1 stop8h 20m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$286
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:16 pm
DSM
- DTW
1 stop21h 19m
Frontier
Sun 5/171:20 pm
DTW
- DSM
1 stop25h 11m
Frontier
Deal found 3/12![Frontier logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:09 am
DSM
- CAK
1 stop5h 34m
American Airlines
Tue 4/146:20 am
CAK
- DSM
1 stop6h 10m
American Airlines
Deal found 3/9![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:20 am
DSM
- DAY
1 stop3h 37m
United Airlines
Sun 4/511:32 am
DAY
- DSM
1 stop3h 53m
United Airlines
Deal found 3/8![United Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
DSM
- DTW
1 stop8h 24m
Multiple Airlines
Sun 4/2610:27 pm
DTW
- DSM
1 stop15h 42m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:30 am
DSM
- CMH
2 stops25h 45m
Multiple Airlines
Sun 4/268:19 pm
CMH
- DSM
1 stop17h 50m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- DTW
1 stop6h 38m
Multiple Airlines
Wed 4/2211:17 am
DTW
- DSM
1 stop27h 29m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:40 am
DSM
- DAY
1 stop4h 31m
American Airlines
Sun 4/55:47 am
DAY
- DSM
2 stops8h 20m
American Airlines
Deal found 3/8![American Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:00 pm
DSM
- DAY
1 stop7h 05m
American Airlines
Sat 3/285:35 pm
DAY
- DSM
1 stop5h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
- CLE
2 stops24h 09m
Multiple Airlines
Sun 5/37:43 pm
CLE
- DSM
1 stop24h 55m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$302
Best flights from Des Moines to OhioDiscover carefully curated flight deals from Des Moines to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 14, 2026.
Discover carefully curated flight deals from Des Moines to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 14, 2026.
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:20 am
DSM
- DAY
1 stop3h 37m
United Airlines
Sun 4/511:32 am
DAY
- DSM
1 stop3h 53m
United Airlines
Deal found 3/8![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:00 pm
DSM
- DAY
1 stop7h 05m
American Airlines
Sat 3/285:35 pm
DAY
- DSM
1 stop5h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
DSM
- PIT
1 stop3h 45m
Southwest
Wed 4/296:05 am
PIT
- DSM
1 stop9h 00m
Southwest
Deal found 3/10![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:33 pm
DSM
- CMH
1 stop6h 00m
Delta
Mon 5/186:44 pm
CMH
- DSM
1 stop4h 48m
Delta
Deal found 3/9![Delta logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:19 pm
DSM
- TOL
1 stop19h 00m
Allegiant Air
Mon 3/3011:09 am
TOL
- DSM
1 stop11h 10m
Allegiant Air
Deal found 3/10![Allegiant Air logo]()
$593
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:02 pm
DSM
- CAK
1 stop5h 43m
American Airlines
Tue 4/146:20 am
CAK
- DSM
1 stop5h 06m
American Airlines
Deal found 3/10![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:23 pm
DSM
- CVG
1 stop6h 21m
Delta
Sat 5/211:55 am
CVG
- DSM
1 stop6h 07m
Delta
Deal found 3/11![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:30 am
DSM
- CVG
2 stops10h 35m
Southwest
Wed 5/208:35 am
CVG
- DSM
1 stop3h 50m
Southwest
Deal found 3/13![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:21 pm
DSM
- PIT
1 stop4h 37m
United Airlines
Sun 4/268:54 am
PIT
- DSM
1 stop4h 35m
United Airlines
Deal found 3/11![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:35 am
DSM
- CLE
1 stop3h 40m
Southwest
Mon 4/67:50 pm
CLE
- DSM
1 stop4h 25m
Southwest
Deal found 3/9![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:23 pm
DSM
- PIT
1 stop6h 35m
Delta
Mon 5/45:41 pm
PIT
- DSM
1 stop4h 31m
Delta
Deal found 3/9![Delta logo]()
$327
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:25 pm
DSM
- PIT
1 stop4h 28m
American Airlines
Mon 5/47:12 pm
PIT
- DSM
1 stop5h 37m
American Airlines
Deal found 3/12![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:16 pm
DSM
- CVG
1 stop3h 42m
United Airlines
Mon 4/66:15 pm
CVG
- DSM
1 stop6h 02m
United Airlines
Deal found 3/13![United Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:47 pm
DSM
- PIT
1 stop3h 59m
Delta
Mon 4/66:30 am
PIT
- DSM
1 stop4h 16m
Delta
Deal found 3/9![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:30 am
DSM
- PIT
2 stops6h 20m
Southwest
Sat 4/48:30 am
PIT
- DSM
1 stop4h 00m
Southwest
Deal found 3/9![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:04 am
DSM
- CAK
1 stop4h 16m
United Airlines
Wed 4/228:15 am
CAK
- DSM
1 stop5h 14m
United Airlines
Deal found 3/8![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:00 pm
DSM
- PIT
1 stop5h 32m
American Airlines
Sun 5/36:12 am
PIT
- DSM
1 stop6h 18m
American Airlines
Deal found 3/14![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:35 am
DSM
- CVG
2 stops7h 25m
Southwest
Sat 5/22:35 pm
CVG
- DSM
1 stop7h 20m
Southwest
Deal found 3/11![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:44 pm
DSM
- PIT
1 stop5h 52m
Delta
Sun 5/36:40 am
PIT
- DSM
1 stop4h 14m
Delta
Deal found 3/9![Delta logo]()
$342
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:16 pm
DSM
- DAY
1 stop3h 43m
United Airlines
Tue 4/148:10 pm
DAY
- DSM
1 stop4h 07m
United Airlines
Deal found 3/8![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:20 pm
DSM
- CVG
1 stop3h 50m
Southwest
Thu 4/309:00 am
CVG
- DSM
1 stop3h 45m
Southwest
Deal found 3/9![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 am
DSM
- PIT
1 stop3h 58m
Delta
Thu 5/286:25 pm
PIT
- DSM
1 stop5h 07m
Delta
Deal found 3/12![Delta logo]()
$347
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:00 am
DSM
- CVG
2 stops7h 25m
American Airlines
Tue 6/165:28 pm
CVG
- DSM
1 stop7h 42m
American Airlines
Deal found 3/11![American Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:20 am
DSM
- CMH
1 stop5h 52m
United Airlines
Mon 4/276:10 am
CMH
- DSM
2 stops7h 19m
United Airlines
Deal found 3/11![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:50 am
DSM
- CLE
1 stop7h 25m
Southwest
Mon 4/208:05 pm
CLE
- DSM
1 stop4h 00m
Southwest
Deal found 3/9![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:10 pm
DSM
- CLE
1 stop6h 28m
United Airlines
Wed 4/87:54 pm
CLE
- DSM
1 stop4h 23m
United Airlines
Deal found 3/9![United Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:30 pm
DSM
- CVG
1 stop4h 25m
Delta
Fri 6/264:40 pm
CVG
- DSM
1 stop6h 46m
Delta
Deal found 3/9![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:30 am
DSM
- DTW
2 stops6h 30m
Southwest
Tue 4/141:20 pm
DTW
- DSM
2 stops9h 50m
Southwest
Deal found 3/11![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:15 am
DSM
- CVG
1 stop6h 46m
United Airlines
Tue 5/57:00 am
CVG
- DSM
1 stop4h 37m
United Airlines
Deal found 3/11![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:30 pm
DSM
- CMH
1 stop4h 29m
Delta
Sun 6/147:00 am
CMH
- DSM
1 stop4h 15m
Delta
Deal found 3/10![Delta logo]()
$387
Last-minute flights from Des Moines to OhioDiscover last-minute flight deals from Des Moines to Ohio. Data last updated March 14, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Ohio. Data last updated March 14, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
DSM
- CLE
1 stop13h 33m
Frontier
Sun 3/228:51 pm
CLE
- DSM
1 stop23h 25m
Frontier
Deal found 3/9![Frontier logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:40 am
DSM
- DTW
1 stop8h 53m
Multiple Airlines
Mon 4/1311:54 am
DTW
- DSM
1 stop8h 20m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:00 pm
DSM
- DAY
1 stop7h 05m
American Airlines
Sat 3/285:35 pm
DAY
- DSM
1 stop5h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$299
This Gotogate deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:21 pm
DSM
- CMH
1 stop21h 17m
Frontier
Sun 3/297:33 pm
CMH
- DSM
1 stop24h 43m
Frontier
Deal found 3/12![Frontier logo]()
$275
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:20 am
DSM
- DAY
1 stop3h 37m
United Airlines
Sun 4/511:32 am
DAY
- DSM
1 stop3h 53m
United Airlines
Deal found 3/8![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:40 am
DSM
- DAY
1 stop4h 31m
American Airlines
Sun 4/55:47 am
DAY
- DSM
2 stops8h 20m
American Airlines
Deal found 3/8![American Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:09 am
DSM
- CAK
1 stop5h 34m
American Airlines
Tue 4/146:20 am
CAK
- DSM
1 stop6h 10m
American Airlines
Deal found 3/9![American Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- DTW
1 stop6h 38m
Multiple Airlines
Wed 4/2211:17 am
DTW
- DSM
1 stop27h 29m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:30 am
DSM
- CMH
2 stops25h 45m
Multiple Airlines
Sun 4/268:19 pm
CMH
- DSM
1 stop17h 50m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
DSM
- DTW
1 stop8h 24m
Multiple Airlines
Sun 4/2610:27 pm
DTW
- DSM
1 stop15h 42m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
- CLE
2 stops24h 09m
Multiple Airlines
Sun 5/37:43 pm
CLE
- DSM
1 stop24h 55m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
DSM
- PIT
1 stop3h 45m
Southwest
Wed 4/296:05 am
PIT
- DSM
1 stop9h 00m
Southwest
Deal found 3/10![Southwest logo]()
$303
One-way flights from Des Moines to OhioSearch for one-way flight options from Des Moines to Ohio. Find affordable one-way fares based on user searches. Data last updated March 14, 2026.
Search for one-way flight options from Des Moines to Ohio. Find affordable one-way fares based on user searches. Data last updated March 14, 2026.
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- DTW
1 stop8h 43m
Frontier
Deal found 3/12![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
DSM
- CVG
1 stop16h 09m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:23 pm
DSM
- DTW
1 stop8h 09m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
- DTW
1 stop32h 04m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
DSM
- DTW
1 stop7h 59m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:45 am
DSM
- DTW
1 stop15h 53m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
DSM
- PIT
1 stop15h 58m
Allegiant Air
Deal found 3/13![Allegiant Air logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:53 pm
DSM
- CVG
1 stop15h 17m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$128
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
- DTW
1 stop6h 21m
Frontier
Deal found 3/9![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:56 pm
DSM
- DTW
2 stops36h 11m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$136
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:21 pm
DSM
- DTW
1 stop13h 38m
Frontier
Deal found 3/10![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:07 pm
DSM
- DTW
2 stops25h 39m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$140
Find flight deals from Des Moines to Ohio
Keep the following information in mind while searching for Des Moines to Ohio flight deals. Data was last updated March 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (Expedia) |
One-way from | $90 (Frontier) |
Popular in | August |
Cheapest in | February |
Average price | $578 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Des Moines to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesDayton
DSM - DAY
DSMDAY
Des Moines
Thu 4/2
6:20 am-10:57 am
1 stop3h 37m
Dayton
Sun 4/5
11:32 am-2:25 pm
1 stop3h 53m
$289
Des MoinesDayton
DSM - DAY
DSMDAY
Des Moines
Tue 3/24
2:00 pm-10:05 pm
1 stop7h 05m
Dayton
Sat 3/28
5:35 pm-10:34 pm
1 stop5h 59m
$299
Des MoinesPittsburgh
DSM - PIT
DSMPIT
Des Moines
Tue 4/28
5:30 am-10:15 am
1 stop3h 45m
Pittsburgh
Wed 4/29
6:05 am-2:05 pm
1 stop9h 00m
$303
Des MoinesAkron
DSM - CAK
DSMCAK
Des Moines
Wed 4/8
2:02 pm-8:45 pm
1 stop5h 43m
Akron/Canton
Tue 4/14
6:20 am-10:26 am
1 stop5h 06m
$309
Des MoinesColumbus
DSM - CMH
DSMCMH
Des Moines
Wed 5/13
2:33 pm-9:33 pm
1 stop6h 00m
Columbus
Mon 5/18
6:44 pm-10:32 pm
1 stop4h 48m
$316
Des MoinesCincinnati
DSM - CVG
DSMCVG
Des Moines
Sat 4/25
4:23 pm-11:44 pm
1 stop6h 21m
Cincinnati Cinci./N. Kentucky
Sat 5/2
11:55 am-5:02 pm
1 stop6h 07m
$317
Des MoinesCincinnati
DSM - CVG
DSMCVG
Des Moines
Wed 5/13
5:30 am-5:05 pm
2 stops10h 35m
Cincinnati Cinci./N. Kentucky
Wed 5/20
8:35 am-11:25 am
1 stop3h 50m
$322
Des MoinesCleveland
DSM - CLE
DSMCLE
Des Moines
Thu 4/2
5:35 am-10:15 am
1 stop3h 40m
Cleveland Hopkins Intl
Mon 4/6
7:50 pm-11:15 pm
1 stop4h 25m
$327
Des MoinesPittsburgh
DSM - PIT
DSMPIT
Des Moines
Thu 4/30
4:23 pm-11:58 pm
1 stop6h 35m
Pittsburgh
Mon 5/4
5:41 pm-9:12 pm
1 stop4h 31m
$327
Des MoinesPittsburgh
DSM - PIT
DSMPIT
Des Moines
Mon 3/30
5:47 pm-10:46 pm
1 stop3h 59m
Pittsburgh
Mon 4/6
6:30 am-9:46 am
1 stop4h 16m
$327
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from Des Moines with our price prediction graph.
DSM-DAY
DSM-PIT
DSM-CMH
DSM-TOL
DSM-CAK
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Ohio
DSM-USOH
DSM-DAY
DSM-PIT
DSM-CMH
DSM-TOL
What is the cheapest month to book a flight from Des Moines to Ohio?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Ohio (average of $108). Flying from Des Moines to Ohio in January is currently the most expensive (average of $309). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated March 14, 2026.
Read through reviews of airlines operating flights from Des Moines to Ohio, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Ohio
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Complete your trip
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Des Moines and Ohio flights
Browse other Des Moines and Ohio flight options. Last updated on March 14, 2026.
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Des Moines to Ohio flights
Consider these flights traveling from Des Moines to Ohio.
Top 4 airlines flying from Des Moines to Ohio
Discover the top 4 airlines that operate flights from Des Moines to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$405 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$381 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$250 | Average$344 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$386 | FlexibilityNo cancel fee | On-time63% |