Panama City

$412+ Cheap flights from South America to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — ECP
Jan 14 — Jan 211
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South America to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South America to Panama City

Cheapest flights from South America to Panama City
Explore the most affordable flight options available from South America to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:45 amMDE - ECP
2 stops51h 42mUnited Airlines
Thu 1/16:15 amECP - MDE
1 stop14h 50mUnited Airlines
Deal found 12/15$715
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:45 amMDE - ECP
2 stops51h 42mUnited Airlines
Wed 12/319:52 amECP - MDE
1 stop11h 13mUnited Airlines
Deal found 12/15$719
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:30 amMDE - ECP
2 stops22h 40mAmerican Airlines
Thu 1/17:15 amECP - MDE
2 stops15h 24mAmerican Airlines
Deal found 12/15$729
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:30 amBOG - ECP
1 stop13h 50mUnited Airlines
Wed 12/246:15 amECP - BOG
1 stop15h 20mUnited Airlines
Deal found 12/14$987
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:35 pmBOG - ECP
2 stops15h 02mDelta
Wed 12/242:20 pmECP - BOG
2 stops20h 45mDelta
Deal found 12/14$999
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:30 amBOG - ECP
2 stops36h 57mUnited Airlines
Fri 12/192:10 pmECP - BOG
2 stops31h 25mUnited Airlines
Deal found 12/13$1,320

Find flight deals from South America to Panama City

Keep the following information in mind while searching for South America to Panama City flight deals. Data was last updated December 15, 2025.

Round-trip from

$514
(Delta)

One-way from

$412
(American Airlines)
From South America to Panama City NW Florida Beaches
One-way flight from South America to Panama City NW Florida Beaches

Cheapflights Fare Finder

 
Customize your flight search to find flights from South America to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from South America to Panama City that are best for you.

Fly from

South America

Fly to

Panama City

Route

Depart

Return

Price

BogotáPanama City

BOG - ECP

BOGECP

Bogotá El Dorado

Tue 4/7

2:55 pm-8:39 am

1 stop17h 44m

Panama City NW Florida Beaches

Tue 4/14

6:00 am-7:25 pm

1 stop13h 25m

$514

BogotáPanama City

BOG - ECP

BOGECP

Bogotá El Dorado

Wed 3/11

3:55 pm-10:13 am

1 stop18h 18m

Panama City NW Florida Beaches

Tue 3/24

7:00 am-4:45 pm

2 stops9h 45m

$514

BogotáPanama City

BOG - ECP

BOGECP

Bogotá El Dorado

Thu 2/26

3:15 pm-9:55 am

2 stops19h 40m

Panama City NW Florida Beaches

Wed 3/18

4:34 pm-11:10 am

2 stops18h 36m

$550

MedellínPanama City

MDE - ECP

MDEECP

Medellín Jose Maria Cordova Intl

Sat 2/14

3:10 pm-12:07 pm

2 stops21h 57m

Panama City NW Florida Beaches

Sun 2/22

4:30 pm-2:06 pm

2 stops20h 36m

$552

BogotáPanama City

BOG - ECP

BOGECP

Bogotá El Dorado

Tue 3/10

1:30 am-1:14 pm

3 stops35h 44m

Panama City NW Florida Beaches

Tue 3/24

2:10 pm-5:10 am

2 stops15h 00m

$572

MedellínPanama City

MDE - ECP

MDEECP

Medellín Jose Maria Cordova Intl

Wed 1/28

3:10 pm-11:33 am

2 stops21h 23m

Panama City NW Florida Beaches

Wed 2/4

3:27 pm-2:06 pm

2 stops21h 39m

$572

MedellínPanama City

MDE - ECP

MDEECP

Medellín Jose Maria Cordova Intl

Sat 2/14

10:45 am-12:04 pm

1 stop26h 19m

Panama City NW Florida Beaches

Sun 2/22

6:30 am-10:05 pm

1 stop14h 35m

$597

MedellínPanama City

MDE - ECP

MDEECP

Medellín Jose Maria Cordova Intl

Sat 2/14

10:45 am-4:11 pm

1 stop30h 26m

Panama City NW Florida Beaches

Tue 2/17

6:30 am-10:05 pm

1 stop14h 35m

$612

BogotáPanama City

BOG - ECP

BOGECP

Bogotá El Dorado

Mon 4/20

12:14 am-4:17 pm

1 stop16h 03m

Panama City NW Florida Beaches

Sat 4/25

4:55 pm-7:20 pm

1 stop26h 25m

$660

LimaPanama City

LIM - ECP

LIMECP

Lima J Chavez Intl

Wed 1/28

12:45 am-5:33 pm

2 stops17h 48m

Panama City NW Florida Beaches

Wed 2/4

7:02 am-5:10 am

2 stops21h 08m

$802

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 30 results
1
2
3

Best time to book a flight from South America to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to Panama City

What is the cheapest month to book a flight from South America to Panama City, Florida?

Currently, March is the cheapest month in which you can book a flight from South America to Panama City, Florida (average of $109). Flying from South America to Panama City, Florida in October is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SA to ECP?

Find hourly flight availability from South America to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from South America to Panama City, Florida, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 32% versus a flight in the evening.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 15, 2025.
Peruse reviews from past customers who have flown with United Airlines from South America to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.7

Food

6.6

Comfort

7.3

Overall

7.4

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

AMS - EWR

It was good! The first 3/4 of the trip was uncomfortably cold. Only one option for lunch that I didn’t enjoy (vegetarian).

Boarding

7.7

Food

6.6

Comfort

7.3

Overall

7.4

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2025

AMS - EWR

It was good! The first 3/4 of the trip was uncomfortably cold. Only one option for lunch that I didn’t enjoy (vegetarian).

Related info for your journey

Find useful and relevant information for your journey from South America to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from South America?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly into when you book flights from South America to Panama City.

  • How long is the flight from South America to Panama City, Florida?

    Departing from South America to Panama City, Florida will take you 17h 44m. The distance between South America and Panama City, Florida is about 1927 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South America to Panama City, Florida?

  • Can I find deals for flights from South America to Panama City that include hotel bookings?

    Yes. In addition to deals on South America to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South America to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Panama City.

  • Can I find deals for business class flights from South America to Panama City?

    Yes. Cheapflights offers flight deals from South America to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South America to Panama City, Florida?

    Currently, March is the cheapest month in which you can book a flight from South America to Panama City, Florida (average of $109). Flying from South America to Panama City, Florida in October is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South America to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from South America to Panama City

Discover the top airline that operate flights from South America to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$496Average$528FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.