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Panama City

$170+ Cheap flights from Moline to Panama City, FL (MLI - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — ECP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Moline to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Moline (MLI) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$249
(Delta)

One-way from

$170
(Delta)

Popular in

December

Cheapest in

January

Average price

$363
From Moline Quad-City to Panama City NW Florida Beaches
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One-way flight from Moline Quad-City to Panama City NW Florida Beaches
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Moline to Panama City

Cheapest flights from Moline to Panama City
Explore the most affordable flight options available from Moline to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:04 pmMLI - ECP
1 stop6h 06mDelta
Sat 11/155:00 pmECP - MLI
1 stop5h 33mDelta
Deal found 9/13$249
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:43 pmMLI - ECP
1 stop6h 10mAmerican Airlines
Sat 11/152:37 pmECP - MLI
2 stops9h 18mAmerican Airlines
Deal found 9/13$254
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:59 pmMLI - ECP
1 stop6h 04mDelta
Wed 10/14:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 9/12$259
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:59 pmMLI - ECP
1 stop6h 04mDelta
Sat 10/45:02 pmECP - MLI
1 stop5h 40mDelta
Deal found 9/13$294
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/204:59 pmMLI - ECP
1 stop6h 04mDelta
Wed 9/244:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 9/13$309
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/164:59 pmMLI - ECP
1 stop6h 04mDelta
Tue 9/234:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 9/15$324
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amMLI - ECP
1 stop6h 30mDelta
Tue 10/215:32 pmECP - MLI
1 stop4h 48mDelta
Deal found 9/13$329
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2710:50 amMLI - ECP
2 stops10h 58mUnited Airlines
Wed 10/11:55 pmECP - MLI
1 stop7h 10mUnited Airlines
Deal found 9/13$334
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/164:59 pmMLI - ECP
1 stop6h 04mDelta
Sat 9/2011:00 amECP - MLI
1 stop5h 19mDelta
Deal found 9/15$339
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:00 amMLI - ECP
2 stops11h 36mAmerican Airlines
Fri 10/33:53 pmECP - MLI
1 stop5h 39mAmerican Airlines
Deal found 9/13$349

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Moline to Panama City that are best for you.

Fly from

Moline

Fly to

Panama City

Route

Depart

Return

Price

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 11/8

5:04 pm-11:10 pm

1 stop6h 06m

Panama City NW Florida Beaches

Sat 11/15

5:00 pm-10:33 pm

1 stop5h 33m

$249

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 11/8

5:43 pm-11:53 pm

1 stop6h 10m

Panama City NW Florida Beaches

Sat 11/15

2:37 pm-11:55 pm

2 stops9h 18m

$254

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

4:59 pm-11:03 pm

1 stop6h 04m

Panama City NW Florida Beaches

Wed 10/1

4:46 pm-10:42 pm

1 stop5h 56m

$259

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

4:59 pm-11:03 pm

1 stop6h 04m

Panama City NW Florida Beaches

Fri 10/3

4:46 pm-10:42 pm

1 stop5h 56m

$259

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 10/11

5:00 pm-10:41 pm

1 stop5h 41m

Panama City NW Florida Beaches

Wed 10/15

5:32 pm-10:20 pm

1 stop4h 48m

$294

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 10/1

4:59 pm-11:03 pm

1 stop6h 04m

Panama City NW Florida Beaches

Sat 10/4

5:02 pm-10:42 pm

1 stop5h 40m

$294

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 2/24

5:00 pm-10:42 pm

1 stop5h 42m

Panama City NW Florida Beaches

Sat 2/28

4:10 pm-10:34 pm

1 stop6h 24m

$294

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

10:50 am-9:48 pm

2 stops10h 58m

Panama City NW Florida Beaches

Wed 10/1

1:55 pm-9:05 pm

1 stop7h 10m

$334

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 12/24

4:59 pm-11:03 pm

1 stop6h 04m

$170

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Moline to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to Panama City

How far ahead should I book a flight from Moline to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Moline to Panama City. Price data was last updated on September 12, 2025.

The best time to book flights from Moline to Panama City, Florida is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Moline to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $346). Flying from Moline to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Moline to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Moline to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Moline to Panama City, Florida?

    There are many flights that can get you from Moline to Panama City, Florida in 6h 06m. Fly via Delta or American Airlines to get the fastest option. Moline and Panama City, Florida are separated by a distance of 809 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Moline to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Moline to Panama City, Florida round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and American Airlines, from $253. Delta is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Moline to Panama City that include hotel bookings?

    Yes. In addition to deals on Moline to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to Panama City.

  • Can I find deals for business class flights from Moline to Panama City?

    Yes. Cheapflights offers flight deals from Moline to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $346). Flying from Moline to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Moline to Panama City

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Top 3 airlines flying from Moline to Panama City

Discover the top 3 airlines that operate flights from Moline to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$345FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$368FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$398FlexibilityNo cancel feeOn-time71%

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