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Panama City

$279+ Cheap flights from Moline to Panama City, FL (MLI - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — ECP
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Moline to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Moline (MLI) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$279
(Delta)

Popular in

May

Cheapest in

January

Average price

$343
From Moline Quad-City to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Moline to Panama City

Cheapest flights from Moline to Panama City
Explore the most affordable flight options available from Moline to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:59 pmMLI - ECP
1 stop6h 04mDelta
Wed 10/14:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 8/13$279
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:06 pmMLI - ECP
1 stop5h 47mAmerican Airlines
Tue 10/143:41 pmECP - MLI
1 stop6h 48mAmerican Airlines
Deal found 8/14$314
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:00 amMLI - ECP
2 stops11h 36mAmerican Airlines
Wed 10/13:53 pmECP - MLI
1 stop5h 39mAmerican Airlines
Deal found 8/13$324
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/164:59 pmMLI - ECP
1 stop6h 07mDelta
Sun 8/176:54 pmECP - MLI
1 stop3h 54mDelta
Deal found 8/14$339
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:04 pmMLI - ECP
1 stop6h 06mDelta
Wed 10/155:32 pmECP - MLI
1 stop4h 48mDelta
Deal found 8/14$344
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:06 pmMLI - ECP
1 stop5h 47mAmerican Airlines
Wed 10/156:44 amECP - MLI
2 stops11h 18mAmerican Airlines
Deal found 8/14$353
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/164:59 pmMLI - ECP
1 stop6h 07mDelta
Thu 8/216:54 pmECP - MLI
1 stop3h 54mDelta
Deal found 8/14$369
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/54:59 pmMLI - ECP
1 stop6h 07mDelta
Mon 9/85:02 pmECP - MLI
1 stop5h 46mDelta
Deal found 8/12$374
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2610:42 amMLI - ECP
1 stop6h 12mAmerican Airlines
Tue 9/26:06 pmECP - MLI
1 stop4h 55mAmerican Airlines
Deal found 8/14$378

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Moline to Panama City that are best for you.

Fly from

Moline

Fly to

Panama City

Route

Depart

Return

Price

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

4:59 pm-11:03 pm

1 stop6h 04m

Panama City NW Florida Beaches

Wed 10/1

4:46 pm-10:42 pm

1 stop5h 56m

$279

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 10/7

5:06 pm-10:53 pm

1 stop5h 47m

Panama City NW Florida Beaches

Tue 10/14

3:41 pm-10:29 pm

1 stop6h 48m

$314

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

6:00 am-5:36 pm

2 stops11h 36m

Panama City NW Florida Beaches

Wed 10/1

3:53 pm-9:32 pm

1 stop5h 39m

$324

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 10/8

5:04 pm-11:10 pm

1 stop6h 06m

Panama City NW Florida Beaches

Wed 10/15

5:32 pm-10:20 pm

1 stop4h 48m

$344

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 10/8

5:06 pm-10:53 pm

1 stop5h 47m

Panama City NW Florida Beaches

Wed 10/15

6:44 am-6:02 pm

2 stops11h 18m

$353

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 9/5

4:59 pm-11:06 pm

1 stop6h 07m

Panama City NW Florida Beaches

Mon 9/8

5:02 pm-10:48 pm

1 stop5h 46m

$374

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 8/26

10:42 am-4:54 pm

1 stop6h 12m

Panama City NW Florida Beaches

Tue 9/2

6:06 pm-11:01 pm

1 stop4h 55m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Best time to book a flight from Moline to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to Panama City

How far ahead should I book a flight from Moline to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Moline to Panama City. Price data was last updated on August 8, 2025.

The best time to book flights from Moline to Panama City, Florida is 85 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Moline to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $346). Flying from Moline to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Moline to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 14, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Moline to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Moline to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Moline to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Moline to Panama City, Florida round-trip from $238. Another airline that can offer you cheap pricing is American Airlines. Delta is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Moline to Panama City that include hotel bookings?

    Yes. In addition to deals on Moline to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to Panama City.

  • Can I find deals for business class flights from Moline to Panama City?

    Yes. Cheapflights offers flight deals from Moline to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $346). Flying from Moline to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Moline to Panama City

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Top 2 airlines flying from Moline to Panama City

Discover the top 2 airlines that operate flights from Moline to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$364FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$399FlexibilityNo cancel feeOn-time71%

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