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Panama City

$204+ Cheap flights from Moline to Panama City, FL (MLI - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — ECP
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Moline to Panama City

Cheapest flights from Moline to Panama City
Explore the most affordable flight options available from Moline to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:12 pm
MLI
-
ECP
1 stop5h 53m
Delta
Wed 5/66:00 am
ECP
-
MLI
1 stop4h 26m
Delta
Deal found 1/20$269
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/212:02 pm
MLI
-
ECP
2 stops9h 47m
American Airlines
Sat 2/281:02 pm
ECP
-
MLI
1 stop5h 30m
American Airlines
Deal found 1/22$274
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:12 pm
MLI
-
ECP
1 stop5h 53m
Delta
Thu 5/76:00 am
ECP
-
MLI
1 stop4h 26m
Delta
Deal found 1/20$300
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/285:11 pm
MLI
-
ECP
1 stop5h 29m
Delta
Tue 2/39:24 am
ECP
-
MLI
1 stop7h 04m
Delta
Deal found 1/19$309
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/283:58 pm
MLI
-
ECP
1 stop5h 21m
American Airlines
Tue 2/312:03 pm
ECP
-
MLI
2 stops10h 23m
American Airlines
Deal found 1/19$314
This Delta deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:00 pm
MLI
-
ECP
1 stop5h 46m
Delta
Sat 8/16:00 am
ECP
-
MLI
1 stop4h 26m
Delta
Deal found 1/22$330
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:12 pm
MLI
-
ECP
1 stop5h 53m
Delta
Sat 5/26:00 am
ECP
-
MLI
1 stop4h 26m
Delta
Deal found 1/20$354

Find flight deals from Moline to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Moline (MLI) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$269
(Delta)

One-way from

$224
(Delta)

Popular in

December

Cheapest in

January

Average price

$319
Provider with most accurate pricing for Moline Quad-City-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Moline Quad-City-Panama City NW Florida Beaches flights.
Search Deals
From Moline Quad-City to Panama City NW Florida Beaches
Search Deals
One-way flight from Moline Quad-City to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Moline to Panama City that are best for you.

Fly from

Moline

Fly to

Panama City

Route

Depart

Return

Price

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Mon 2/16

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Tue 2/24

5:00 pm-10:24 pm

1 stop5h 24m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sun 2/15

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Tue 2/24

5:00 pm-10:24 pm

1 stop5h 24m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 4/4

2:02 pm-11:49 pm

2 stops9h 47m

Panama City NW Florida Beaches

Tue 4/7

7:21 am-12:27 pm

1 stop5h 06m

$274

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 5/2

11:00 am-6:00 pm

1 stop7h 00m

Panama City NW Florida Beaches

Thu 5/7

6:00 am-10:26 am

1 stop4h 26m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 4/4

5:14 pm-11:04 pm

1 stop5h 50m

Panama City NW Florida Beaches

Tue 4/7

5:30 pm-10:30 pm

1 stop5h 00m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 5/1

5:12 pm-11:05 pm

1 stop5h 53m

Panama City NW Florida Beaches

Thu 5/7

6:00 am-10:26 am

1 stop4h 26m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 5/1

5:12 pm-11:05 pm

1 stop5h 53m

Panama City NW Florida Beaches

Wed 5/6

6:00 am-10:26 am

1 stop4h 26m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 5/2

11:00 am-3:19 pm

1 stop4h 19m

Panama City NW Florida Beaches

Tue 5/5

6:00 am-10:26 am

1 stop4h 26m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 5/1

5:12 pm-11:05 pm

1 stop5h 53m

Panama City NW Florida Beaches

Fri 5/8

6:00 am-10:26 am

1 stop4h 26m

$300

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Fri 4/10

5:14 pm-11:04 pm

1 stop5h 50m

Panama City NW Florida Beaches

Tue 4/14

5:20 pm-10:35 pm

1 stop5h 15m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Showing 1-10 of 16 results
1
2

Compare providers for flights from Moline to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Moline to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Moline-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Moline-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Moline-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Moline-Panama City, Florida flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Moline-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Moline to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to Panama City

What is the cheapest month to book a flight from Moline to Panama City, Florida?

Currently, June is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $129). Flying from Moline to Panama City, Florida in August is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 22, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Moline to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,087 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,087 reviews
Delta
7.9
Good
8,087 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
9,190 reviews
Delta
7.9
Good
8,087 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,087 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Moline to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Moline to Panama City, Florida?

    There are many flights that can get you from Moline to Panama City, Florida in 5h 38m. Fly via Delta to get the fastest option. Moline and Panama City, Florida are separated by a distance of 809 mi.

  • What are the cheapest airlines flying from Moline to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Moline to Panama City, Florida round-trip from $232. Other airlines that can offer you cheap pricing are American Airlines, from $259, and United Airlines, from $278. Delta is currently priced 41% below the average price you’ll pay for this route.

  • Can I find deals for flights from Moline to Panama City that include hotel bookings?

    Yes. In addition to deals on Moline to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to Panama City.

  • Can I find deals for business class flights from Moline to Panama City?

    Yes. Cheapflights offers flight deals from Moline to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to Panama City, Florida?

    Currently, June is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $129). Flying from Moline to Panama City, Florida in August is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Alternative routes for Moline to Panama City

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Top 3 airlines flying from Moline to Panama City

Discover the top 3 airlines that operate flights from Moline to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$398FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$259Average$396FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$278Average$338FlexibilityNo cancel feeOn-time69%

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