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Panama City

$205+ Cheap flights from Moline to Panama City, FL (MLI - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — ECP
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Moline to Panama City

Cheapest flights from Moline to Panama City
Explore the most affordable flight options available from Moline to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:43 pmMLI - ECP
1 stop6h 10mAmerican Airlines
Mon 12/2911:11 amECP - MLI
2 stops8h 06mAmerican Airlines
Deal found 12/20$359
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:30 amMLI - ECP
1 stop6h 57mUnited Airlines
Mon 12/292:10 pmECP - MLI
1 stop7h 11mUnited Airlines
Deal found 12/20$369
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:35 pmMLI - ECP
2 stops9h 18mAmerican Airlines
Fri 1/26:46 amECP - MLI
1 stop8h 05mAmerican Airlines
Deal found 12/22$997
This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:50 amMLI - ECP
1 stop4h 27mDelta
Mon 12/299:22 amECP - MLI
1 stop6h 54mDelta
Deal found 12/20$1,058
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:30 amMLI - ECP
2 stops26h 47mUnited Airlines
Fri 1/26:15 amECP - MLI
2 stops15h 06mUnited Airlines
Deal found 12/21$1,144
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:43 pmMLI - ECP
1 stop6h 15mAmerican Airlines
Fri 1/22:52 pmECP - MLI
2 stops8h 48mAmerican Airlines
Deal found 12/21$1,181

Find flight deals from Moline to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Moline (MLI) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(Delta)

One-way from

$205
(Delta)

Popular in

December

Cheapest in

January

Average price

$488
Provider with most accurate pricing for Moline Quad-City-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Moline Quad-City-Panama City NW Florida Beaches flights.
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From Moline Quad-City to Panama City NW Florida Beaches
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One-way flight from Moline Quad-City to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 1% potential increase in price ($7 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Moline to Panama City that are best for you.

Fly from

Moline

Fly to

Panama City

Route

Depart

Return

Price

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Mon 2/16

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Tue 2/24

5:00 pm-10:24 pm

1 stop5h 24m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 1/28

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

Tue 2/3

9:24 am-4:28 pm

1 stop7h 04m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Wed 1/28

7:31 am-5:33 pm

2 stops10h 02m

Panama City NW Florida Beaches

Tue 2/3

12:03 pm-10:26 pm

2 stops10h 23m

$279

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Mon 1/26

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

Sat 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$299

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sun 2/15

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Sat 2/21

12:10 pm-4:16 pm

1 stop4h 06m

$299

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sun 1/25

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

Sat 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$299

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Tue 1/27

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

Sat 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$299

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Thu 1/1

5:43 pm-11:53 pm

1 stop6h 10m

Panama City NW Florida Beaches

Sat 2/28

6:44 am-3:04 pm

1 stop8h 20m

$334

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 2/14

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Thu 2/19

6:06 pm-10:24 pm

1 stop4h 18m

$334

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 2/14

5:01 pm-10:39 pm

1 stop5h 38m

Panama City NW Florida Beaches

Fri 2/20

6:06 pm-10:24 pm

1 stop4h 18m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 12 results
1
2

Compare providers for flights from Moline to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Moline to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Moline-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Moline-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Moline-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Moline-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Moline-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Moline to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to Panama City

What is the cheapest month to book a flight from Moline to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $116). Flying from Moline to Panama City, Florida in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 23, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Moline to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,014 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
9,105 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Moline to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Moline to Panama City, Florida?

    There are many flights that can get you from Moline to Panama City, Florida in 5h 38m. Fly via Delta or American Airlines to get the fastest option. Moline and Panama City, Florida are separated by a distance of 809 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Moline to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Moline to Panama City, Florida round-trip from $232. Other airlines that can offer you cheap pricing are American Airlines, from $259, and United Airlines, from $278. Delta is currently priced 41% below the average price you’ll pay for this route.

  • Can I find deals for flights from Moline to Panama City that include hotel bookings?

    Yes. In addition to deals on Moline to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to Panama City.

  • Can I find deals for business class flights from Moline to Panama City?

    Yes. Cheapflights offers flight deals from Moline to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from Moline to Panama City, Florida (average of $116). Flying from Moline to Panama City, Florida in November is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Top 3 airlines flying from Moline to Panama City

Discover the top 3 airlines that operate flights from Moline to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$259Average$400FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$278Average$345FlexibilityNo cancel feeOn-time69%

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